Identifying 3D expression domains by graph clustering
... These expression levels help identify the state of the chromatin, as ‘closed’ chromatin will result in lower expression levels compared to ‘open’ chromatin. Before the publication of the TRIP method this generally required low throughput analyses as reporters could only target specific genomic l ...
... These expression levels help identify the state of the chromatin, as ‘closed’ chromatin will result in lower expression levels compared to ‘open’ chromatin. Before the publication of the TRIP method this generally required low throughput analyses as reporters could only target specific genomic l ...
Ingenuity Upstream Regulator Analysis in IPA®
... that can explain the observed gene expression changes in a user’s dataset, which can help illuminate the biological activities occurring in the tissues or cells being studied. IPA makes it easy to take this result even further by examining what biological processes, pathways, and diseases the tra ...
... that can explain the observed gene expression changes in a user’s dataset, which can help illuminate the biological activities occurring in the tissues or cells being studied. IPA makes it easy to take this result even further by examining what biological processes, pathways, and diseases the tra ...
PubMed Advanced: Linking PubMed to NCBI Genetics Databases
... Use “Links” to the right of the citation Choose the NCBI database of interest ...
... Use “Links” to the right of the citation Choose the NCBI database of interest ...
Agrobacterium-mediated transformation of banana Musa acuminata
... transgenic plants at first generation (T0) of transformation. To prove the existence of hpt gene in the fruits of transgenic banana plants, PCR analysis were also carried out. The data showed that the hpt gene could be amplified from banana fruits of tested samples. These result demonstrates that th ...
... transgenic plants at first generation (T0) of transformation. To prove the existence of hpt gene in the fruits of transgenic banana plants, PCR analysis were also carried out. The data showed that the hpt gene could be amplified from banana fruits of tested samples. These result demonstrates that th ...
Genetic or epigenetic difference causing discordance between
... may be selectively amplified in the healthy co-twin. It has been postulated that loss of imprinting itself caused twinning. This can explain the higher rate of twins in BWS. Recently, it was reported that children born by in vitro fertilization (IVF) is more frequently seen in BWS (4%, 6/149) compar ...
... may be selectively amplified in the healthy co-twin. It has been postulated that loss of imprinting itself caused twinning. This can explain the higher rate of twins in BWS. Recently, it was reported that children born by in vitro fertilization (IVF) is more frequently seen in BWS (4%, 6/149) compar ...
Inflorescence Meristem Identity in Rice Is Specified
... domain proteins usually function in complexes with other, related MADS domain proteins (reviewed in Gramzow and Theissen, 2010), we postulated that the effects of the loss of PAP2 activity during reproductive phase transition may be masked by redundancy with other gene(s). To test this idea, we sear ...
... domain proteins usually function in complexes with other, related MADS domain proteins (reviewed in Gramzow and Theissen, 2010), we postulated that the effects of the loss of PAP2 activity during reproductive phase transition may be masked by redundancy with other gene(s). To test this idea, we sear ...
Imprinting capacity of gamete lineages in C. elegans
... When two or more plasmids are mixed, the extra-chromosomal transgene array consists of tandem mixed arrays of the two sequences, with a total copy number of 100-200. By rearing populations at 23°C, we select for pha-1(+) animals that harbor the transgene array. A single clonal line from the plasmid ...
... When two or more plasmids are mixed, the extra-chromosomal transgene array consists of tandem mixed arrays of the two sequences, with a total copy number of 100-200. By rearing populations at 23°C, we select for pha-1(+) animals that harbor the transgene array. A single clonal line from the plasmid ...
AthaMap web tools for database-assisted identification of
... behind the factor name (Table 1). The binding sites were taken directly from the published literature, which is regularly screened in the process of updating the TRANSFAC1 database with plant transcription factor data (2). The screens were performed on the most recent version of the A.thaliana genom ...
... behind the factor name (Table 1). The binding sites were taken directly from the published literature, which is regularly screened in the process of updating the TRANSFAC1 database with plant transcription factor data (2). The screens were performed on the most recent version of the A.thaliana genom ...
The evolution of genomic imprinting and X
... Another similarity between the PWS-AS domain and the XIC is that both their evolutionary histories were demarcated by genomic rearrangement. I discovered that the protein coding genes in the region homologous to the XIC of marsupials and monotremes independently underwent fission (Figures 3.3 and 3. ...
... Another similarity between the PWS-AS domain and the XIC is that both their evolutionary histories were demarcated by genomic rearrangement. I discovered that the protein coding genes in the region homologous to the XIC of marsupials and monotremes independently underwent fission (Figures 3.3 and 3. ...
Nucleotide Sequence of the SAC2 Gene of Saccharomyces cerevisiae .
... to 10 days at 11°C. Temperature-sensitivity of into M13 derivatives (Messing, 1983) and seactl-1 and suppression by SAC2 mutations were quenced by standard dideoxy sequencing methods scored after 3 days at 37°C. Growth tests were (Sanger et al., 1977). performed by spotting suspensions of cells in w ...
... to 10 days at 11°C. Temperature-sensitivity of into M13 derivatives (Messing, 1983) and seactl-1 and suppression by SAC2 mutations were quenced by standard dideoxy sequencing methods scored after 3 days at 37°C. Growth tests were (Sanger et al., 1977). performed by spotting suspensions of cells in w ...
Proceedings of the National Academy of Sciences
... intracellular zinc may be in the range of 1025 M. Zinc transport was induced by growth in zinc. The cadA gene is regulated by the CadC repressor (32), a member of the ArsR family of metalloregulatory proteins (33). However, no genes for homologs of CadC or ArsR are located near zntA, and there are n ...
... intracellular zinc may be in the range of 1025 M. Zinc transport was induced by growth in zinc. The cadA gene is regulated by the CadC repressor (32), a member of the ArsR family of metalloregulatory proteins (33). However, no genes for homologs of CadC or ArsR are located near zntA, and there are n ...
Transferrin receptor 2 (TfR2) and HFE mutational analysis in non
... mixed ethnic backgrounds. Several sequence variants were identified within the TfR2 gene, including a homozygous missense change in exon 17, c2069 A3C, which changes a glutamine to a proline residue at position 690. This putative mu- ...
... mixed ethnic backgrounds. Several sequence variants were identified within the TfR2 gene, including a homozygous missense change in exon 17, c2069 A3C, which changes a glutamine to a proline residue at position 690. This putative mu- ...
Comparative Genetic Mapping Revealed Powdery Mildew
... isolates collected from different regions of China. These Bgt isolates were also used to test the reactions of Pm36 and MlWE4. Both Pm36 and MlWE4 showed same resistance reaction patterns as that of Ml3D232 and PmAS846, indicating that Ml3D232, PmAS846, Pm36, and MlWE4 are most likely the same gene ...
... isolates collected from different regions of China. These Bgt isolates were also used to test the reactions of Pm36 and MlWE4. Both Pm36 and MlWE4 showed same resistance reaction patterns as that of Ml3D232 and PmAS846, indicating that Ml3D232, PmAS846, Pm36, and MlWE4 are most likely the same gene ...
Centronuclear Myopathy Testing for Families
... If someone does not have any changes in MTM1, DNM2, BIN1 or RYR1, then his/her CNM is most likely not caused by problems in the gene that was tested. There are probably changes in other genes that cause CNM that we do not yet know about, so negative MTM1, DNM2, BIN1 and/or RYR1 testing does not rule ...
... If someone does not have any changes in MTM1, DNM2, BIN1 or RYR1, then his/her CNM is most likely not caused by problems in the gene that was tested. There are probably changes in other genes that cause CNM that we do not yet know about, so negative MTM1, DNM2, BIN1 and/or RYR1 testing does not rule ...
Divining Biological Pathway Knowledge from High
... has edges connecting it to LDHB and AKR1B1. These edges indicate that those genes belong to the Pyruvate metabolism pathway. ...
... has edges connecting it to LDHB and AKR1B1. These edges indicate that those genes belong to the Pyruvate metabolism pathway. ...
Chromosome Band 1p36 Contains a Putative Tumor
... region 1p36. Cloning of candidate gene(s) will define whether either a single or multiple tumor suppressor genes are clustered on 1p and are commonly involved in these types of tumors. The p18INK4c gene is located on 1p32 and it is regarded as a tumor suppressor gene.24 Homozygous deletions of the p ...
... region 1p36. Cloning of candidate gene(s) will define whether either a single or multiple tumor suppressor genes are clustered on 1p and are commonly involved in these types of tumors. The p18INK4c gene is located on 1p32 and it is regarded as a tumor suppressor gene.24 Homozygous deletions of the p ...
Evolutionary relationships and diversification of barhl genes within
... mutations and are functionally lost (non-functionalization [3,4]) or acquire a new function (neo-functionalization), or split the ancestral function between the paralogs (sub-functionalization) [2]), therefore adding complexity to the developmental gene network that shapes organ formation. The genes ...
... mutations and are functionally lost (non-functionalization [3,4]) or acquire a new function (neo-functionalization), or split the ancestral function between the paralogs (sub-functionalization) [2]), therefore adding complexity to the developmental gene network that shapes organ formation. The genes ...
New Construct Approaches for Efficient Gene Silencing in Plants
... Hua Yan, Robert Chretien, Jingsong Ye, and Caius M. Rommens* Simplot Plant Sciences, J.R. Simplot Company, Boise, Idaho 83706 ...
... Hua Yan, Robert Chretien, Jingsong Ye, and Caius M. Rommens* Simplot Plant Sciences, J.R. Simplot Company, Boise, Idaho 83706 ...
clinchem.org - Clinical Chemistry
... deletions or duplications and decreases costs because it does not require expensive fluorescent reagents. © 2006 American Association for Clinical Chemistry ...
... deletions or duplications and decreases costs because it does not require expensive fluorescent reagents. © 2006 American Association for Clinical Chemistry ...
Information Encoding in Biological Molecules: DNA and protein
... • Current methods for classifying human malignancies rely on a variety of morphological, clinical, and molecular variables. • In spite of recent progress, there are still uncertainties in diagnosis. Also, it is likely that the existing classes are heterogeneous. • DNA microarrays may be used to char ...
... • Current methods for classifying human malignancies rely on a variety of morphological, clinical, and molecular variables. • In spite of recent progress, there are still uncertainties in diagnosis. Also, it is likely that the existing classes are heterogeneous. • DNA microarrays may be used to char ...
Evaluation of Nyholt`s Procedure for Multiple Testing Correction
... in a haplotype block or gene) whose union is S. Nyholt (2004) mentions that his approach may be conservative in the presence of very strong LD. Our empirical results, on the other hand, show that it tends to become anti-conservative. The website of the SNPSpD program contains a note describing a wa ...
... in a haplotype block or gene) whose union is S. Nyholt (2004) mentions that his approach may be conservative in the presence of very strong LD. Our empirical results, on the other hand, show that it tends to become anti-conservative. The website of the SNPSpD program contains a note describing a wa ...
UvA-DARE (Digital Academic Repository)
... is shown in Figure 1A. The family history further revealed that an uncle died unexpectedly at the age of 48 years late in the evening while he was out to inspect his cattle and a great grandfather also died suddenly at young age. Because of this impressive family history the 44 year old woman receiv ...
... is shown in Figure 1A. The family history further revealed that an uncle died unexpectedly at the age of 48 years late in the evening while he was out to inspect his cattle and a great grandfather also died suddenly at young age. Because of this impressive family history the 44 year old woman receiv ...
AAV-mediated Gene Therapy Restores Cone Function In A Rat With
... and the causative mutation. To develop a gene therapy, two AAV vectors were constructed. The first was a serotype 5 AAV with the human red opsin promoter (PR2.1) driving expression of a human L-opsin cDNA (hROps). The second was a serotype 8 AAV containing a Y-F mutation at capsid position 733 (AAV8 ...
... and the causative mutation. To develop a gene therapy, two AAV vectors were constructed. The first was a serotype 5 AAV with the human red opsin promoter (PR2.1) driving expression of a human L-opsin cDNA (hROps). The second was a serotype 8 AAV containing a Y-F mutation at capsid position 733 (AAV8 ...