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Managing Diabetes
Managing Diabetes

... 2003. Nearly 21 million Americans have diabetes. The breakdown by age group shows that of Americans who have diabetes, 2 percent are ages 20 to 39 and 40 percent are 65 or older. However, the number of children with type 2 diabetes is increasing rapidly. About 5 million Americans have diabetes but d ...
Drs. Xiangqin Cui and Rui Feng Awarded Faculty Development Grant
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... Drs. Xiangqin Cui and Rui Feng Awarded Faculty Development Grant July 22, 2008 Kudos go to Drs. Xiangqin Cui and Rui Feng who have been awarded a $30,000 Faculty Development Grant for the 2008-09 academic year for their proposal, entitled “Toward the Integration of Genomics and Epigenomics – a Pilot ...
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... tissue sample is valuable information about a person s health. By studying the language of cells, genes and proteins, researchers can better understand disease development, including how cancer progresses. DNA methylation, which helps control gene expression, and chromatin structures, protein-DNA in ...
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... Diabetes Mellitus is a disease that occurs when the body is not able to use sugar as it should. The body needs sugar for growth and energy for daily activities, and it gets sugar when it changes food into glucose (a form of sugar). A hormone called insulin is needed for the glucose to be used by the ...
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... as genes and proteins, and interactions between them that collectively carry out some cellular function. A genetic regulatory network refers to the network of controls that turn on/off gene transcription. ...
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... exons of the INSR gene were screened for variation. Several changes were reported including some novel polymorphisms. However, there was no report of the polymorphisms at codon 233, 234 and 276 [18]. Thus, our observations on INSR gene polymorphism are in conformity with the studies conducted on sev ...
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Epigenetics and the exposomes: Obesity and beyond

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... 8. Regulation of gene expression in eukaryotes is considered much more complex than in prokaryotes. Why do you think that is? 9. What is the role of enhancers and silencers in transcriptional regulation? 10. Describe the three different DNA binding motifs associated with transcription factors. 11. U ...
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Use of methylation profiling to identify genes involved in relapse in
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... are usually methylation free. In cancerous cells these same regions frequently exhibit hypermethylation, leading to stable gene inactivation. ...
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Epigenetics of diabetes Type 2

In recent years it has become apparent that the environment and underlying mechanisms affect gene expression and the genome outside of the central dogma of biology. It has been found that many Epigenetic mechanisms are involved in the regulation and expression of genes such as DNA methylation and chromatin remodeling. These epigenetic mechanisms are believed to be a contributing factor to pathological diseases such as Diabetes type II. An understanding of the epigenome of Diabetes patients may help to elucidate otherwise hidden causes of this disease.
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