ANTIDIABETIC POTENTIAL OF MEDICINAL PLANTS
... sugar level in experimental animals. C. esculenta root extract has influence on protein metabolism and marker enzymes in streptozotocin-induced diabetic rats. The study revealed that C. esculenta root extract has the antihyperglycemic effect and it may elevate liver and renal damage associated with ...
... sugar level in experimental animals. C. esculenta root extract has influence on protein metabolism and marker enzymes in streptozotocin-induced diabetic rats. The study revealed that C. esculenta root extract has the antihyperglycemic effect and it may elevate liver and renal damage associated with ...
Expression of Phosphofructokinase in Skeletal Muscle Is
... that bimodality may be an underlying factor in disease development (1). In a more recent study, cis-eQTL effects were compared between blood and four nonblood tissues (including liver, subcutaneous, and visceral adipose tissue and skeletal muscle), which provided new insights into the mechanisms by ...
... that bimodality may be an underlying factor in disease development (1). In a more recent study, cis-eQTL effects were compared between blood and four nonblood tissues (including liver, subcutaneous, and visceral adipose tissue and skeletal muscle), which provided new insights into the mechanisms by ...
MPI-Plant-Katagiri
... strategy for a research community to deal with competing developments? Wolf-R Scheible Forward genetics had not been very successful with nitrogen-regulation studies due to functionally duplicated genes (recent duplication of the genome is common in plants). Therefore, a reverse genetic approach was ...
... strategy for a research community to deal with competing developments? Wolf-R Scheible Forward genetics had not been very successful with nitrogen-regulation studies due to functionally duplicated genes (recent duplication of the genome is common in plants). Therefore, a reverse genetic approach was ...
Genetic Associations of Obesity: The Fat-Mass and Obesity
... by Rodrigues et al.14 In a longitudinal study of 146 patients undergoing Roux-en-Y gastric bypass, researchers performed genotypic analysis of the rs9939609 SNP and assessed its role in postoperative weight gain. Patients without the risk allele (TT) were compared to patients with one (TA) or two (A ...
... by Rodrigues et al.14 In a longitudinal study of 146 patients undergoing Roux-en-Y gastric bypass, researchers performed genotypic analysis of the rs9939609 SNP and assessed its role in postoperative weight gain. Patients without the risk allele (TT) were compared to patients with one (TA) or two (A ...
Gene disruption-Why?
... Identification of the Dyclonine Target -Dyclonine: active ingredients of Sucrets -Give a profile like Ergosterol mutant Phenotype similar to Erg2 (sterol isomerase) -Human Sigma receptor is closest to Erg2 -Sigma receptor regulate K+ conductance ...
... Identification of the Dyclonine Target -Dyclonine: active ingredients of Sucrets -Give a profile like Ergosterol mutant Phenotype similar to Erg2 (sterol isomerase) -Human Sigma receptor is closest to Erg2 -Sigma receptor regulate K+ conductance ...
Chapter 11 Notes
... nucleus, but have ribosomes. Hemoglobin mRNA last the lifetime of the RBC (~ a month). B. Initiation of Translation 1. There are proteins that control the initiation of ...
... nucleus, but have ribosomes. Hemoglobin mRNA last the lifetime of the RBC (~ a month). B. Initiation of Translation 1. There are proteins that control the initiation of ...
Participation to Symposia (last 10 years) :
... First Doctoral Thesis in Molecular Biology, University of Paris Doctoral Thesis in Molecular Biology, University of Paris ...
... First Doctoral Thesis in Molecular Biology, University of Paris Doctoral Thesis in Molecular Biology, University of Paris ...
Email Submission: Robert Oppenheimer 1. Which option/s do you
... degeneration of the gene drive and any associated genes by random mutation, leading to complete silencing and less frequently to the reemergence of new gene drives with a different genetic sequence. We should expect synthetic gene drives will continue to evolve long after they have propagated a ‘use ...
... degeneration of the gene drive and any associated genes by random mutation, leading to complete silencing and less frequently to the reemergence of new gene drives with a different genetic sequence. We should expect synthetic gene drives will continue to evolve long after they have propagated a ‘use ...
Genes
... Only a fraction of eukaryotic DNA codes for proteins or RNA molecules: 1.1% of human genome represents protein-coding genes Coding regions are not continuous ( Split genes), contains exons and introns. Introns often account for most of the gene size.: BRCA-1 (Chr 17) 100,000 bp. Codes for a protein ...
... Only a fraction of eukaryotic DNA codes for proteins or RNA molecules: 1.1% of human genome represents protein-coding genes Coding regions are not continuous ( Split genes), contains exons and introns. Introns often account for most of the gene size.: BRCA-1 (Chr 17) 100,000 bp. Codes for a protein ...
Chapter Outline
... 2. Tumor-suppressor genes normally act as brakes on cell division when it begins to occur abnormally. 3. When proto-oncogenes mutate, they become oncogenes. 4. Tumor-suppressor genes and proto-oncogenes often code for transcription factors or proteins that control transcription factors. 5. P53, a ma ...
... 2. Tumor-suppressor genes normally act as brakes on cell division when it begins to occur abnormally. 3. When proto-oncogenes mutate, they become oncogenes. 4. Tumor-suppressor genes and proto-oncogenes often code for transcription factors or proteins that control transcription factors. 5. P53, a ma ...
Data/hora: 06/05/2017 09:28:36 Biblioteca(s): Embrapa Soja. Data
... Of the 100 tribes formed, 50 of them contained more than three unisequences. A list of the 169 unisequences were obtained, that combine defining features to be common between effectors, such as small open reading frame ORF size (<250aa), no intracellular function described, enrichement of cystein re ...
... Of the 100 tribes formed, 50 of them contained more than three unisequences. A list of the 169 unisequences were obtained, that combine defining features to be common between effectors, such as small open reading frame ORF size (<250aa), no intracellular function described, enrichement of cystein re ...
1) In a single molecule of water, the two hydrogen atoms are bonded
... Central Dogma + Endomembrane System = Your Quiz Starting at the level of the gene, describe how a secretory protein called pepsinogen, a digestive enzyme, is made, modified and secreted into the stomach. Be sure to discuss how and where every macromolecule is made starting at the gene level includin ...
... Central Dogma + Endomembrane System = Your Quiz Starting at the level of the gene, describe how a secretory protein called pepsinogen, a digestive enzyme, is made, modified and secreted into the stomach. Be sure to discuss how and where every macromolecule is made starting at the gene level includin ...
Section 3 - Applying statistical Tests to Microarray Data
... Self-self hybridization • Need for normalization seen in self-self hybridizations in which the same mRNA sample is labelled red & green: ...
... Self-self hybridization • Need for normalization seen in self-self hybridizations in which the same mRNA sample is labelled red & green: ...
Big data mining yields novel insights on cancer
... Figure 1 PCA of gene expression. (a) PCA is applied to array profiles to decompose them into different PCs. (b) Pearson correlation of PC coefficients helps infer genes with similar functions. (c) Consecutive genes on a chromosome with high or low PC coefficients reflect SCNAs in cancer samples. ...
... Figure 1 PCA of gene expression. (a) PCA is applied to array profiles to decompose them into different PCs. (b) Pearson correlation of PC coefficients helps infer genes with similar functions. (c) Consecutive genes on a chromosome with high or low PC coefficients reflect SCNAs in cancer samples. ...
Regulation of Eukaryotic Genes
... Illustrative example: promoters 3B.1a.2: A regulatory gene is a sequence of DNA encoding a regulatory protein or RNA. 3B.1c: In eukaryotes, gene expression is complex and control involves regulatory genes, regulatory elements and transcription factors act in concert. 3B.1c.1: Transcription factors b ...
... Illustrative example: promoters 3B.1a.2: A regulatory gene is a sequence of DNA encoding a regulatory protein or RNA. 3B.1c: In eukaryotes, gene expression is complex and control involves regulatory genes, regulatory elements and transcription factors act in concert. 3B.1c.1: Transcription factors b ...
View Poster - Technology Networks
... Apomixis is a trait which confers to flowering plants the ability to produce seeds by asexual mechanisms. One of its most studied forms is gametophytic apomixis, in which a diploid embryo sac develops parthenogenetically (without meiosis) to form a viable embryo. The evidence for genetic basis of th ...
... Apomixis is a trait which confers to flowering plants the ability to produce seeds by asexual mechanisms. One of its most studied forms is gametophytic apomixis, in which a diploid embryo sac develops parthenogenetically (without meiosis) to form a viable embryo. The evidence for genetic basis of th ...
Presentation - people.vcu.edu
... Weng, Y.-I., Huang, T. H.-M., & Yan, P. S. (2009). Methylated DNA Immunoprecipitation and Microarray-Based Analysis: Detection of DNA Methylation in Breast Cancer Cell Lines. Methods in Molecular Biology (Clifton, N.J.), 590, 165–176. ...
... Weng, Y.-I., Huang, T. H.-M., & Yan, P. S. (2009). Methylated DNA Immunoprecipitation and Microarray-Based Analysis: Detection of DNA Methylation in Breast Cancer Cell Lines. Methods in Molecular Biology (Clifton, N.J.), 590, 165–176. ...
Supplementary Materials (doc 54K)
... multiplexed assay, total RNA (3 μL) was reverse transcribed into cDNA and amplified by PCR using biotin-modified primers (35 cycles of 94°C for 30 sec, 55°C for 30 sec, 72°C for 30 sec). GAPDH transcripts were co-detected in the same reaction as endogenous internal controls. The PCR products were th ...
... multiplexed assay, total RNA (3 μL) was reverse transcribed into cDNA and amplified by PCR using biotin-modified primers (35 cycles of 94°C for 30 sec, 55°C for 30 sec, 72°C for 30 sec). GAPDH transcripts were co-detected in the same reaction as endogenous internal controls. The PCR products were th ...
Functional genomics strategy from gene discovery to evaluation of
... comparison to control cells. SAT2 cDNA encodes a 70-kDa protein which is 67 % identical to the Arabidopsis GA MYB-binding protein (AtSAT2). To further examine salinity tolerance in Arabidopsis, we functionally characterized the AtSAT2 gene and found that dehydration as well as abscisic acid (ABA) in ...
... comparison to control cells. SAT2 cDNA encodes a 70-kDa protein which is 67 % identical to the Arabidopsis GA MYB-binding protein (AtSAT2). To further examine salinity tolerance in Arabidopsis, we functionally characterized the AtSAT2 gene and found that dehydration as well as abscisic acid (ABA) in ...
Is it on or off? The Use of Microarrays in Functional Genomics
... of all patients currently do not respond to standard therapy for diffuse large B cell lymphoma; the reason is that there are various forms of the disease caused by aberrant molecular abnormalities, thus making the cancer more potent than usual. By using microarrays, physicians hope to be able to id ...
... of all patients currently do not respond to standard therapy for diffuse large B cell lymphoma; the reason is that there are various forms of the disease caused by aberrant molecular abnormalities, thus making the cancer more potent than usual. By using microarrays, physicians hope to be able to id ...
Supplementary Materials and methods (doc 46K)
... threshold value across the ten permutations. When similar CV values were obtained, we selected the threshold yielding the smallest set of genes and lowest FDR given by pamr. Similarly, ten permutations of three fold CV were performed for determining the threshold in the BCP multivariate comparisons ...
... threshold value across the ten permutations. When similar CV values were obtained, we selected the threshold yielding the smallest set of genes and lowest FDR given by pamr. Similarly, ten permutations of three fold CV were performed for determining the threshold in the BCP multivariate comparisons ...