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Slide 1
Slide 1

... Only a small amount (percentage) of human DNA contains information that is ostensibly converted into proteins: these sequences are associated with genes. The proteins coded for by genes do biochemical work and regulate cell division, generate energy, respond to the environment, provide immunity to i ...
Chromatin modifying activity of leukaemia associated fusion proteins
Chromatin modifying activity of leukaemia associated fusion proteins

... DNA methylation represses gene transcription by creating docking site for methyl-CpG binding domain (MBD) proteins, which selectively recognize methylated CpG dinucleotides (16). The presence of MBD proteins within methylated promoters could prevent gene activation by precluding ...
Investigation of the role of expanded gene families
Investigation of the role of expanded gene families

... In addition to the InterPro data, complete protein sequences from each individual organism were clustered into related sets by running BlastClust at different percentage identities over varying lengths of the sequences. The proteins common to both InterPro duplicate gene clusters and sequence based ...
PPT: Genetics: From Mendel to Genome and Epigenome
PPT: Genetics: From Mendel to Genome and Epigenome

... hypothesis of Boveri and Sutton that genes are located on chromosomes. • Expanded the idea of genetic linkage and hypothesized the phenomenon of crossing over. • He proposed that the amount of crossing over between linked genes differs and that crossover frequency might indicate the distance between ...
BOLIVARIAN REPUBLIC OF VENEZUELA
BOLIVARIAN REPUBLIC OF VENEZUELA

... By definition, a selfish gene works only for itself, using any mean necessary for its survival in the next generations1. And by any mean, it includes the destruction of other genes while it is inserted in the DNA, and, the unique ability to multiply inside the genome so that the gene can have as man ...
Slide 1
Slide 1

... Transposable elements have the ability to move from one place in the genome to another. ...
EGAN - iPlant Pods
EGAN - iPlant Pods

... Can be configured and launched from a different application (e.g. GenePattern) Analyses can be scripted for automation ...
Diapositive 1
Diapositive 1

... characterize retinal genes. This protocol has been applied to the design of the preliminary list of RetChip and validated on an larger pool of genes (Genoret Genes). To query these information, querying forms have been developed allowing the user to retrieve the Genoret Gene Identity Card (GIC) by g ...
Gene Expression Changes in Goat Testes During Development and
Gene Expression Changes in Goat Testes During Development and

... the age is shown. Representative sections for the various age groups were hybridized with radiolabeled sense cRNA probe (Sense) serves as a negative control. ...
Readme file describing the networks/expression data
Readme file describing the networks/expression data

... In this directory you can download various data associated with the PlaNet database. Description of the files: -CelFileID.zip contains names of the cel files used to construct the PlaNet database. -PlaNetStandalone.zip: Stand-alone version of PlaNet implemented in Python. In addition, expression dat ...
Fish sampling - BioMed Central
Fish sampling - BioMed Central

... L37 are shown in Table 2. As an indication of tissue distribution of the studied genes, Ct values in the six tissues are shown in Fig. 5. All assays were based on ESTs we have sequenced as part of a largescale Atlantic cod sequencing effort and subsequently uploaded to the Genbank. Gene annotations ...
Genetics after Mendel
Genetics after Mendel

... dominance Lower organisms ...
MGG330 L1-2007
MGG330 L1-2007

... As name suggests for measuring expression Most genes in Genome covered From a variety of organisms ...
Chapter 12 Notes
Chapter 12 Notes

... – In gene therapy, a defective gene is replaced with a copy of a healthy gene. – Somatic cell gene therapy alters only body cells. – Germ cell gene therapy attempts to alter eggs or sperm. ...
genetic engineering - Skinners` School Science
genetic engineering - Skinners` School Science

... • Rice plants have the gene for beta carotene (photosynthetic pigment) but in the endosperm of rice it is not expressed • Need to add genes for “Phytoene synthetase” from daffodils and “Crt enzyme” from soil bacteria Erwinia uredovora for beta carotene to be made in endosperm • These 2 genes were in ...
Automatic Annotation of Gene Lists from Literature Analysis
Automatic Annotation of Gene Lists from Literature Analysis

... Coverage is not even in all areas. E.g. ecology and behavior; medicine; anatomy and physiology; etc. ...
A. Restriction Enzymes
A. Restriction Enzymes

... This technique is used to separate cut up segments of DNA based on size. The pattern that is created is called a DNA fingerprint ...
Leukaemia Section t(1;14)(q25;q32) Atlas of Genetics and Cytogenetics in Oncology and Haematology
Leukaemia Section t(1;14)(q25;q32) Atlas of Genetics and Cytogenetics in Oncology and Haematology

... the 5’ regulatory region of the Lhx4 gene in a head-tohead configuration. LHX4 mRNA is expressed at high levels; case 2: the breakpoint fuses the J4 segment of IgH to sequences located 16kb from LHX4 Exon 1 in a head-to-head configuration. LHX4 mRNA is expressed at high levels. ...
LINEs in Human Genome
LINEs in Human Genome

... Insertions of the Alu element into the intron of the NF-1 (neurofibromatosis type I) gene may lead to neurofibromatosis ...
Pedigree
Pedigree

... offspring • affected individuals can be male or female ...
Mathematical Modelling - Mathematical Association
Mathematical Modelling - Mathematical Association

... Hereditary traits are determined by genes, which occur on every cell of an organism, grouped together on the chromosomes. Except in the reproductive cells genes occur in pairs and appear on paired chromosomes. A particular gene with two alleles R and r. The genes of an offspring result from the pair ...
Identification of ORC1/CDC6-interacting factors in
Identification of ORC1/CDC6-interacting factors in

... -You work in teams of two, presenting groups are randomly chosen at each data* - Introductions (given in red letters) are presented by volunteers (who don´t have to prepare the paper seminars) - The group that presented one paper will not be presenting another on the same day - Imagine you did the s ...
Press release
Press release

... trial of AMT-060, its proprietary, investigational gene therapy, in patients with severe hemophilia B. The updated data show that all patients in the low-dose cohort have sustained improvements in their disease phenotype and continue to maintain durable levels of Factor IX (FIX) gene activity for up ...
Gene Duplication and Gene Families
Gene Duplication and Gene Families

... freed from the constraints of natural selection and allowed to accumulate mutational changes without phenotypic effect. They may evolve modified, or more rarely, completely different functions. Even when genes in a family have similar functions they may be expressed in different tissues and at diffe ...
Bacterial Transformation with (pGLO Plasmid)
Bacterial Transformation with (pGLO Plasmid)

... DNA in the form of a plasmid • Reinforce the following process: DNA  RNA  Protein  Trait • Observe how genes are regulated ...
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Epigenetics of diabetes Type 2

In recent years it has become apparent that the environment and underlying mechanisms affect gene expression and the genome outside of the central dogma of biology. It has been found that many Epigenetic mechanisms are involved in the regulation and expression of genes such as DNA methylation and chromatin remodeling. These epigenetic mechanisms are believed to be a contributing factor to pathological diseases such as Diabetes type II. An understanding of the epigenome of Diabetes patients may help to elucidate otherwise hidden causes of this disease.
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