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Genetics Vocabulary
Genetics Vocabulary

... Genetics Vocabulary ...
Name Date “Bill Nye: Genes” Video Worksheet 1. Where do your
Name Date “Bill Nye: Genes” Video Worksheet 1. Where do your

... 11. What do genes do? They tell cells what to do 12. Mom tells Richie: Genes are the set of chemical instructions that get passed down from Parent to child. In the process, of course, the genetic material is recombined in new ways, which is why some people bear resemblance to their Parents and Grand ...
Introduction to Genetic - Home
Introduction to Genetic - Home

... Errors in recombination are responsible for mutations called translocations, such as occur in leukemias and other cancers. Normal recombination produces genetic variation by the exchange of genetic material between paired chromosomes. ...
Cancer - Siegel Science
Cancer - Siegel Science

... GENE changes and this causes the cell to function and develop differently from a normal cell. • Carcinogens = cancer causing agents • Examples? • UV light, X-rays, chemicals in cigarette smoke • Inheritance = mutations that are passed from parent to child • Examples? • Colon cancer, breast cancer, o ...
BioSc 231 Exam 5 2008
BioSc 231 Exam 5 2008

Mutations
Mutations

... "latent" effects. These variations, found in coding regions, are not harmful on their own, However, such mutations cause some people to be at higher risk for some diseases such as cancer, but only after exposure to certain environmental agents. They may also explain why one person responds to a drug ...
Histone Modifications
Histone Modifications

... during development. Homeobox genes are defined as those that contain an 180-base-pair sequence that encodes a DNA-binding helix–lturn–helix motif (a homeodomain). (Nature) • The remaining orthologous regions between human and mouse ...
View a technical slide presentation
View a technical slide presentation

... EXZACTTM is Based on Zinc-Finger Proteins • ZFPs are the most abundant class of transcription factors occurring in nature — DNA binding proteins - αββ — sequence specificity is determined by key residues in the protein structure ...
Chapter 13 – Genetic Engineering
Chapter 13 – Genetic Engineering

... producing a successful mutant. – Ex – bacteria that can digest oil have been produced this way ...
Chapter 13 – Genetic Engineering
Chapter 13 – Genetic Engineering

... producing a successful mutant. – Ex – bacteria that can digest oil have been produced this way ...
Chapter 13 – Genetic Engineering
Chapter 13 – Genetic Engineering

... – Ex – bananas, citrus fruit, strawberries, many ornamental flowers Diploid corn Tetraploid corn ...
Transcription is the process by which RNA polymerase copies a
Transcription is the process by which RNA polymerase copies a

... Scientists were experimenting with different DNA stains other than DAPI. They found that when they used Pyronin Y they stained another substance called RNA. The picture below shows a group of cells that were stained with both DAPI (blue) and Pyronin Y (Red in high concentrations, orange in low conce ...
组蛋白甲基化
组蛋白甲基化

... 组蛋白磷酸化 Serine (S), Threonine (T) Phosphorylation 组蛋白泛素化 Lysine (K) Ubiquitination 组蛋白SUMO化 Lysine (K) Sumoylation 组蛋白糖基化 Glutamate, Arginine (R) ADP-Ribosylation ...
Students Visit DNA Learning Center
Students Visit DNA Learning Center

... The size of the genome is about 165 million bases and contains and estimated 12,000 genes (by comparison, the human genome has 3,300 million bases and may have about 70,000 genes; yeast has about 5800 genes in 13.5 million base bases). ...
Gene Section SASH1 (SAM and SH3 domain containing 1)
Gene Section SASH1 (SAM and SH3 domain containing 1)

... The mRNA as well as protein expression of SASH1 was strongly and significantly reduced in colon cancer of UICC stage II, III, and IV, as well as in colorectal liver metastases. In contrast, SASH1 expression was not significantly altered in benign adenomas and in early stage lesions (UICC I). Around ...
Genetics Online Scavenger Hunt
Genetics Online Scavenger Hunt

The Structure of DNA
The Structure of DNA

...  DNA - the genetic material required for the ...
Abstract Submission Form
Abstract Submission Form

Concerning mitochondrial DNA:
Concerning mitochondrial DNA:

... 2. Mutations in which gene are least likely to be associated with breast cancer if inherited in the germ-line? A. B. C. D. E. ...
Common types of DNA damage Different types of repair fix different
Common types of DNA damage Different types of repair fix different

... DNA repair by the baseexcision repair pathway (BER). (a) A DNA glycosylase recognizes a damaged base and cleaves between the base and deoxyribose in the backbone. (b) An AP endonuclease cleaves the phosphodiester backbone near the AP site. (c) DNA polymerase I initiates repair synthesis from the fre ...
Central Dogma.pptx
Central Dogma.pptx

... DNA’s message (gene) is expressed (turned on) by first being transcribed into RNA (mRNA, tRNA or rRNA) mRNA=messenger RNA, carries DNA’s message to be later translated into proteins with the help of tRNA and the ribosome. ...
Nucleic Acids DNA & RNA
Nucleic Acids DNA & RNA

... • RNA is similar to DNA except: 1. has one strand instead of two strands. 2. has uracil instead of thymine 3. has ribose instead of deoxyribose ...
Genetic Control of Metabolism
Genetic Control of Metabolism

... Improvements made to microbes include; • Amplifying specific steps in a metabolic pathway or removing inhibitors to increase the yield of desired product. • The ability to secrete product into the surrounding medium. This allows it to be collected easily, saving resources. • Ensuring it can’t surviv ...
3.1 Teacher Notes
3.1 Teacher Notes

... b. Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product. i. These are often proteins ...
Biotechnological Methods and Products
Biotechnological Methods and Products

... and avoid damage Technically more difficult to construct than recombinant plasmid Disabled virus may regain diseasecausing properties ...
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Cancer epigenetics



Cancer epigenetics is the study of epigenetic modifications to the genome of cancer cells that do not involve a change in the nucleotide sequence. Epigenetic alterations are as important as genetic mutations in a cell’s transformation to cancer, and their manipulation holds great promise for cancer prevention, detection, and therapy. In different types of cancer, a variety of epigenetic mechanisms can be perturbed, such as silencing of tumor suppressor genes and activation of oncogenes by altered CpG island methylation patterns, histone modifications, and dysregulation of DNA binding proteins. Several medications which have epigenetic impact are now used in several of these diseases.
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