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Genes can encode proteins or non
Genes can encode proteins or non

... retrotransposon) and reinserted into the genome. This process is considered non-conservative, since each round makes a new DNA element. Excisions of transposons can be catalyzed by some transposases. These can be identified by loss of an associated marker. Often excision is imprecise and results in ...
Zhang-worms
Zhang-worms

... and gaps by X-ray, 12C, and 18Ar-ion beam irradiation. (3) A checkpoint kinase Ce-atl-1 (ATM/ATR like 1) was also involved in repair for X-ray and UV damages of mitotic and meiotic cells. ...
gene duplication
gene duplication

... chromosomes.  A polyploid organism has more than two sets of chromosomes.  E.g. A diploid (2n chromosomes) organism can become tetraploid (4n), [where n refers to one set of chromosomes]. ...
Genes can encode proteins or non
Genes can encode proteins or non

... retrotransposon) and reinserted into the genome. This process is considered non-conservative, since each round makes a new DNA element. Excisions of transposons can be catalyzed by some transposases. These can be identified by loss of an associated marker. Often excision is imprecise and results in ...
Diversity
Diversity

Gene Section GFI1B (growth factor independent 1B transcription repressor)
Gene Section GFI1B (growth factor independent 1B transcription repressor)

a genetic and epidemiological study of hereditary non
a genetic and epidemiological study of hereditary non

... Study the usefulness of MSI & IHC in diagnosing HNPCC To screen first degree relatives of HNPCC patients for MMR mutation ...
Transcription & Translation
Transcription & Translation

...  Produce proteins that control the action of other genes Example: Homeotic Genes in insects; HOX genes in Mammals. Actions of Regulator Genes ...
No Slide Title
No Slide Title

... (A) two non-polar molecules associate with each other in a polar environment (B) a positively charged particle is attracted to a negatively ...
ppt - Chair of Computational Biology
ppt - Chair of Computational Biology

Preventing Cancer
Preventing Cancer

... About 41% of the US population is expected to be diagnosed with cancer during their lifetime. In 2009, an estimated 562,340 people died from cancer-related causes. Obesity, lack of physical activity, and poor diet may account for about one-third of these deaths. What is cancer? Cancer is a group of ...
Pre – AP Biology
Pre – AP Biology

... before they could reproduce; thereby “wiping” out those genes and eventually causing the extinction of the old species. ...
Gene Technology
Gene Technology

... Issues associated with genetic engineering  There is a protein know as the lac repressor ...
DNA, RNA and Proteins
DNA, RNA and Proteins

... Proteins called DNA polymerases catalyze the formation of the DNA molecule. The polymerases add nucleotides that pair with each base to form two new double helixes. DNA polymerases also have a “proofreading” function. During DNA replication, errors sometimes occur, and the wrong nucleotide is added ...
Gene 5102-96
Gene 5102-96

... In the other, the RNA silencing strategy, non-homologous recombination resulted in the introduction into the chromosome of a DNA construct in which a constitutive promoter controls synthesis of an RNA containing an inverted repeat of the specific gene sequence. ...
The F plasmid and conjugation
The F plasmid and conjugation

... (e.g., Leu+ is a bacteria with that does not need leucine to grow, and Leu- is a bacteria that does need leucine to grow.) ...
Adult stem cells
Adult stem cells

Chapter 7
Chapter 7

Causes of Cancer
Causes of Cancer

Central Dogma: Molecular GeneKcs
Central Dogma: Molecular GeneKcs

... chromosomes are composed of genes alleles on different chromosomes assort independently Theory of natural selection heritable variation differential reproductive success ...
DNA Worksheet
DNA Worksheet

Multiple Endocrine Neoplasia, type 2 (MEN2)
Multiple Endocrine Neoplasia, type 2 (MEN2)

... What is my risk for cancer if I have a RET gene mutation? If you have a RET gene mutation, you have a greater risk of developing certain types of cancers and benign tumors of the endocrine system. The endocrine system is made up of endocrine glands, which secrete hormones to control important functi ...
first of four for Chapter 9
first of four for Chapter 9

... • Multiple-antibiotic resistance units can be assembled to form integron. • An integron is a DNA element which encodes a site-specific recombinase as well as a recognition sequence that allows other similar elements to join the integron. • A cassette is a circular antibiotic-resistancecoding region ...
Introduction Presentation
Introduction Presentation

... (similar to allelic differences in DNA sequence, different functional forms of a protein (allozymes) can sometimes be observed; allozymes were the predominant genetic marker used in fisheries from the 1970s to the 1990s) http://www.dnalc.org/resources/3d/17-sickle-cell.html ...
E. Coli - mrkeay
E. Coli - mrkeay

... 1. Heat DNA to 94-96°C to separate strands 2. Two primers (chunks of single-stranded DNA) are made which correspond to the beginning and end of DNA to be copied 3. Heat to 72°C to extend primers using Taq ...
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Cancer epigenetics



Cancer epigenetics is the study of epigenetic modifications to the genome of cancer cells that do not involve a change in the nucleotide sequence. Epigenetic alterations are as important as genetic mutations in a cell’s transformation to cancer, and their manipulation holds great promise for cancer prevention, detection, and therapy. In different types of cancer, a variety of epigenetic mechanisms can be perturbed, such as silencing of tumor suppressor genes and activation of oncogenes by altered CpG island methylation patterns, histone modifications, and dysregulation of DNA binding proteins. Several medications which have epigenetic impact are now used in several of these diseases.
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