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Glossary OF terms in Spinal Cord Injury Research
Glossary OF terms in Spinal Cord Injury Research

... term to refer to a period when there is still continuing damage. This time period is controversial. Some investigators consider the period to be relatively short, i.e. several hours during which treatments can be given to prevent progressive or secondary tissue damage. Other investigators may consid ...
Targeting Axonal Protein Synthesis in Neuroregeneration and Degeneration REVIEW Jimena Baleriola
Targeting Axonal Protein Synthesis in Neuroregeneration and Degeneration REVIEW Jimena Baleriola

NG2 cells response to axonal alteration in the spinal cord white
NG2 cells response to axonal alteration in the spinal cord white

... two phenomena are still not fully understood, especially at the early stage of neuropathogenesis. Previous studies have reported that abnormal neurofilament aggregates are often associated with decreases in the level of NFL mRNA, for instance, more than 70% downregulation of NFL mRNA was detected in ...
Text S1.
Text S1.

The mechanical control of nervous system development
The mechanical control of nervous system development

Biology 211 Anatomy & Physiology I
Biology 211 Anatomy & Physiology I

Lab Activity Sheets
Lab Activity Sheets

...  Unfortunately, materials such as viruses and bacterial toxins might also be transported from the synaptic knobs to the cell bodies (which are usually in the brain or spinal cord) where they can do extensive damage. Several diseases enter the CNS (central nervous system) this way e.g. polio, rabies ...
ppt file
ppt file

... the pyramids, they decussate, which means that the axons within this fiber bundle cross from the left side of the brain to the right side of the brain. The cortex on the right side of the brain send and receives information from the left side of the body. I do not know why this is the case but it me ...
tissue homework
tissue homework

... 3- Relate the functions of epithelial tissue to its structure. 4- Contrast the three shapes of epithelial tissue. 5- Describe how epithelial tissue may be arranged. 6- Describe the main types of covering epithelium. 7- Compare the different types of exocrine glands. 8- List the main types of connect ...
Organization of Somatic Nervous system, Spinal nerve and Reflex arc
Organization of Somatic Nervous system, Spinal nerve and Reflex arc

... 3, Axon hillock;Origin 4. No rough ER--No protein synthesis 5. Axon terminal 6. Chromatophilic-----no Nissl body ...
Spontaneous plasticity in the injured spinal cord
Spontaneous plasticity in the injured spinal cord

Neuropilin-2 Regulates the Development of Select Cranial and
Neuropilin-2 Regulates the Development of Select Cranial and

Synapse formation in developing neural circuits.
Synapse formation in developing neural circuits.

... There are two general categories of synapses: electrical synapses and chemical synapses. Physiologists and neuropharmacologists functionally defined these two categories of synapses well before they were visualized by cell biologists (Cowan and Kandel, 2001). But the cell biological work that procee ...
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text

... cells in these ganglia project their axons back into the spinal nerves to innervate smooth muscle and glands at the periphery (Purves, Fig. 21.2). At sacral levels S2-S4- the intermediolateral cell column contains the preganglionic, parasympathetic neurons (Purves, Fig. 21.1). Neural pathways in th ...
FIGURE LEGENDS FIGURE 34.1 Somatic and autonomic styles of
FIGURE LEGENDS FIGURE 34.1 Somatic and autonomic styles of

... vulgaris) innervating myenteric ganglion neurons (blue, stained with Cuprolinic blue) in the stomach ...
A horizontal spinal cord slice preparation for studying descending
A horizontal spinal cord slice preparation for studying descending

... A horizontal spinal cord slice preparation for studying descending synaptic inputs to neurons in the mouse spinal cord J.R. Flynn,1 M.P. Galea,2 A.M. Brichta,1 R.J. Callister1 and B.A. Graham ,1 1School of Biomedical Sciences, University of Newcastle, Callaghan, NSW 2308, Australia and Hunter Medica ...
Physiology2 - Sheet#2 - Dr.Loai Alzgoul
Physiology2 - Sheet#2 - Dr.Loai Alzgoul

... Physiology2 - Sheet#2 - Dr.Loai Alzgoul - Done By: Maryam Breik The brain receives all the sensations from the whole body (zlma msh'3ol :P ) , but its response differs according to the type of sensation. Some senses go through slow sensation pathway, while others take the fast sensation pathway. Wh ...
Untitled - inetTeacher
Untitled - inetTeacher

Neuronal Migration
Neuronal Migration

... Experiments on brain slices provided evidence that Slit can regulate migration of SVZa cells in their natural migratory pathway. Functional blocking of Slit using the extracellular part of Robo reduced the repulsive effect of the septum on SVZa cells, indicating that Slit contributes to the endogeno ...
Can regenerating axons recapitulate developmental
Can regenerating axons recapitulate developmental

Abstract
Abstract

Bursting the unfolded protein response accelerates axonal
Bursting the unfolded protein response accelerates axonal

Cellular localization of RNA expression in central and peripheral
Cellular localization of RNA expression in central and peripheral

... (DA)-related CNS disorders. Zhang et al. have studied the cellular mechanisms underlying these actions and have found that CB2R genes and receptors are expressed in midbrain DA neurons, and that activation of CB2Rs receptors inhibits DA neuronal firing and intravenous cocaine self administration11. ...
Lecture - Lawrence Moon
Lecture - Lawrence Moon

... • e.g. contralateral red nucleus • e.g. ipsilateral spinal cord • If we can understand why not, it may be possible to exploit spared axons to cause repair. • Possible new therapies! ...
MicroRNA ablation affects Bergmann glial morphology and disrupts
MicroRNA ablation affects Bergmann glial morphology and disrupts

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Netrin



Netrins are a class of proteins involved in axon guidance. They are named after the Sanskrit word ""netr"", which means ""one who guides."" Netrins are genetically conserved across nematode worms, fruit flies, frogs, mice, and humans. Structurally, netrin resembles the extracellular matrix protein laminin.Netrins are chemotropic; a growing axon will either move towards or away from a higher concentration of netrin. Though the detailed mechanism of axon guidance is not fully understood, it is known that netrin attraction is mediated through UNC-40/DCC cell surface receptors and repulsion is mediated through UNC-5 receptors. Netrins also act as growth factors, encouraging cell growth activities in target cells. Mice deficient in netrin fail to form the hippocampal comissure or the corpus callosum.A proposed model for netrin activity in the spinal column of developing human embryos is that netrins are released by the floor plate and then are picked up by receptor proteins embedded in the growth cones of axons belonging to neurons in the developing spinal column. The bodies of these neurons remain stationary while the axons follow a path defined by netrins, eventually connecting to neurons inside the embryonic brain by developing synapses. Research supports that new axons tend to follow previously traced pathways, rather than being guided by netrins or related chemotropic factors.
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