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Evolution of Gene Expression
Evolution of Gene Expression

... global trends in the evolution of gene expression. Rather, microarrays, which are short DNA sequences complementary to transcribed sequences from a particular species arrayed onto a filter or a microchip, have been used to quantitatively compare the abundance of RNA from hundreds to thousands of exp ...
Outline Why? Fold change Statistical testing with the t-test
Outline Why? Fold change Statistical testing with the t-test

Creating a Gene Map - Southington Public Schools
Creating a Gene Map - Southington Public Schools

... In prophase I of meiosis, homologous chromosomes pair up and tangle together to form a “tetrad”. In a tetrad the two chromosomes undergo a process known as crossing over. Because of crossing over, genes on the same chromosome can end up with different arrangements of alleles than they had before mei ...
Slide 1
Slide 1

... ‘But you know what? In which ways a woman is just like us and in which ways she is very different – nu, on this I am still working’.” (Amos Oz, A Tale of Love and Darkness) ...
1 - western undergrad. by the students, for the students.
1 - western undergrad. by the students, for the students.

... regulating the expression of the gene from which they were transcribed. the association of nucleotides with the elongating RNA transcript. ...
Computational methods for the analysis of bacterial gene regulation
Computational methods for the analysis of bacterial gene regulation

... of all the annotated genes in an organism. Most of these experiments are performed using DNA microarrays, but other techniques such as DNA macroarrays and large scale quantitative rtPCR are also available 21. A new technique that is currently up and coming is RNA sequencing 2 ...
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File

Interpretation of Arabidopsis Thaliana and T
Interpretation of Arabidopsis Thaliana and T

Presentation - University of Warwick
Presentation - University of Warwick

... Deregulation of the c-Myc (Carcinoma Myelocytomatosis) proto-oncogene is seen in many human cancers. The protein product is a transcription factor that works in a heterodimeric complex with the protein Max (figure 1). This complex controls cell cycle progression (G1 to S phase), inhibits terminal di ...
Multifarious microarray-based gene expression patterns in response
Multifarious microarray-based gene expression patterns in response

How do I find a list of genes in a genomic region using the UCSC
How do I find a list of genes in a genomic region using the UCSC

Supplementary Figures
Supplementary Figures

... lincRNAs to investigate a role for TEs in lincRNA transcriptional regulation. Validating our TSS predictions, we observed similar profiles of the known activating histone modification H3K4me3 for lincRNAs and protein coding genes (Supplementary Figure 4). We compared and contrasted the TE compositio ...
Answer Key
Answer Key

Clock-Controlled Genes
Clock-Controlled Genes

... phosphorylation in the mitochondria. The detailed analysis of this pathway suggested a circadian rhythm in the energy metabolism and redox state of SCN neurons. A major surprise was the relatively small overlap of rhythmic transcripts between different tissues examined. In the study by Panda et al. ...
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T. caerulescens

Christine Yiwen Yeh - The Second Draft: The Human Epigenome for novel Diagnoses and Therapies
Christine Yiwen Yeh - The Second Draft: The Human Epigenome for novel Diagnoses and Therapies

... genome annotation on this second level of gene expression it is more possible to pinpoint functional or cell type-specific regions in studies. (2) Cell Identity Epigenomic maps can also provide more information than simple gene expression data. With epigenetics, it is possible to deduce chromatin st ...
Biol 1406 notes Ch 18 8thed
Biol 1406 notes Ch 18 8thed

...  A cluster of proteins called a transcription initiation complex assembles on the promoter sequence at the upstream end of the gene.  One component, RNA polymerase II, transcribes the gene, synthesizing a primary RNA transcript or pre-mRNA.  RNA processing includes enzymatic addition of a 5 cap ...
Gene Regulation and Genetics
Gene Regulation and Genetics

... Abnormal placement of the DNA methylation tags also develops with aging. The tags can decrease in number in some genes, and increase in others, causing inappropriate decreases or increases in the activity of the genes affected. The changes in the placement of the methyl tags may be responsible for a ...
chapter 19 the organization and control of eukaryotic genomes
chapter 19 the organization and control of eukaryotic genomes

...  Interactions between enhancers and specific transcription factors called activators or repressors are important in controlling gene expression.  An activator is a protein that binds to an enhancer to stimulate transcription of a gene.  Protein-mediated bending of DNA brings bound activators in c ...
Differential Gene Expression
Differential Gene Expression

Lecture 6
Lecture 6

Gene Section LOXL3 (lysyl oxidase-like 3) Atlas of Genetics and Cytogenetics
Gene Section LOXL3 (lysyl oxidase-like 3) Atlas of Genetics and Cytogenetics

... This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 2.0 France Licence. © 2009 Atlas of Genetics and Cytogenetics in Oncology and Haematology ...
Protein Synthesis Powerpoint
Protein Synthesis Powerpoint

... - 5’ cap is added (a single G nucleotide) - A poly A tail is added to the 3’ end (50-250 adenine nucleotides) * These are both added for protection against cellular enzymes and also facilitate ribosomal binding. * They are NOT translated as part of the protein. ...
Chapter 15: The Chromosomal Basis of Inheritance
Chapter 15: The Chromosomal Basis of Inheritance

... black and one orange. A female can end up with cells that have both active X with orange alleles or active X with black alleles. Males typically cannot be calico because they only inherit one X chromosome. • Genomic imprinting - certain genes can be imprinted depending on whether the gene resides in ...
Slide 1
Slide 1

... information flow from genes to proteins – Mainly controlled at the level of transcription – A gene that is “turned on” is being transcribed to produce mRNA that is translated to make its corresponding protein – Organisms respond to environmental changes by controlling gene expression ...
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Long non-coding RNA

Long non-coding RNAs (long ncRNAs, lncRNA) are non-protein coding transcripts longer than 200 nucleotides. This somewhat arbitrary limit distinguishes long ncRNAs from small regulatory RNAs such as microRNAs (miRNAs), short interfering RNAs (siRNAs), Piwi-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs), and other short RNAs.
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