Guidelines for the management of basal cell carcinoma
... margins but the recurrence rate varies from 17-58%. The lowest rates were for lateral margin involvement only. The higher rates were for deep and lateral margin involvement, for tumours which were previously recurrent and those which had been treated by radiotherapy. 28-29,31-34 In a series of 187 i ...
... margins but the recurrence rate varies from 17-58%. The lowest rates were for lateral margin involvement only. The higher rates were for deep and lateral margin involvement, for tumours which were previously recurrent and those which had been treated by radiotherapy. 28-29,31-34 In a series of 187 i ...
Characterizing the Grape Transcriptome
... The strategies outlined above will be aided by genomics efforts to characterize the gene content of grapes, such as those involving expressed sequence tag (EST) screens. ESTs currently represent the most abundant nucleotide commodity from plant genomes, providing a resource that can be exploited for ...
... The strategies outlined above will be aided by genomics efforts to characterize the gene content of grapes, such as those involving expressed sequence tag (EST) screens. ESTs currently represent the most abundant nucleotide commodity from plant genomes, providing a resource that can be exploited for ...
Chapter 18: Gene Mutation and DNA Repair
... Having discussed spontaneous mutations we now move on to induced mutations, which are those caused by environmental agents. These agents are called mutagens, and can be physical or chemical. As you proceed through this section, you should become familiar with the major classes of mutagens, which are ...
... Having discussed spontaneous mutations we now move on to induced mutations, which are those caused by environmental agents. These agents are called mutagens, and can be physical or chemical. As you proceed through this section, you should become familiar with the major classes of mutagens, which are ...
Identification of a Novel Point Mutation of Mouse Proto
... corpuscular volume (MCV, the average volume of individual RBC); mean corpuscular hemoglobin (MCH, the average weight of hemoglobin in a red blood cell); mean corpuscular hemoglobin concentration (MCHC, the ratio of MCH to MCV); platelet counts (PLT); and mean platelet volume (MPV, the average volume ...
... corpuscular volume (MCV, the average volume of individual RBC); mean corpuscular hemoglobin (MCH, the average weight of hemoglobin in a red blood cell); mean corpuscular hemoglobin concentration (MCHC, the ratio of MCH to MCV); platelet counts (PLT); and mean platelet volume (MPV, the average volume ...
P57: Beckwith-Wiedemann Syndrome
... p57 is paternally imprinted in the genome IGFII is maternally imprinted in the genome Genomic imprinting is the reversible modification of DNA that causes differential expression of maternally or paternally inherited genes A gene which is imprinted, is inactivated, by being methylated Impr ...
... p57 is paternally imprinted in the genome IGFII is maternally imprinted in the genome Genomic imprinting is the reversible modification of DNA that causes differential expression of maternally or paternally inherited genes A gene which is imprinted, is inactivated, by being methylated Impr ...
Temporal and Spatial Expression of Homeotic Genes Is Important for
... (Hosoya et al., 1995), and differentially regulates the expression of over 400 genes (Egger et al., 2002). gcm also regulates the expression of genes, such as, reverse polarity (repo) (Halter et al., 1995; Xiong et al., 1994), which encodes a homeodomain protein and is expressed exclusively in almos ...
... (Hosoya et al., 1995), and differentially regulates the expression of over 400 genes (Egger et al., 2002). gcm also regulates the expression of genes, such as, reverse polarity (repo) (Halter et al., 1995; Xiong et al., 1994), which encodes a homeodomain protein and is expressed exclusively in almos ...
Calcitonin
... Calcitonin is a 32-amino acid polypeptide hormone that is produced in humans primarily by the parafollicular (also known as C-cells) of the thyroid, and in many other animals in the ultimobranchia body. It acts to reduce blood calcium (Ca2+), opposing the effects of parathyroid hormone(PTH). It has ...
... Calcitonin is a 32-amino acid polypeptide hormone that is produced in humans primarily by the parafollicular (also known as C-cells) of the thyroid, and in many other animals in the ultimobranchia body. It acts to reduce blood calcium (Ca2+), opposing the effects of parathyroid hormone(PTH). It has ...
Cloning of a Novel Na+-Dependent L
... hydropathy patterns. Indeed, a serine transport activity was detected in WAT9 cells harboring the plasmid carrying the sdaC gene from H. influenzae (Fig. 1). However, a Na+stimulated serine activity was observed in WAT9/pSHC4 cells, though the SdaC of E. coli is the H+-coupled serine transport syste ...
... hydropathy patterns. Indeed, a serine transport activity was detected in WAT9 cells harboring the plasmid carrying the sdaC gene from H. influenzae (Fig. 1). However, a Na+stimulated serine activity was observed in WAT9/pSHC4 cells, though the SdaC of E. coli is the H+-coupled serine transport syste ...
- California State University
... necessitates willingness to accept that firm conclusions cannot be drawn about the exact nature of any functional significance of amino acid changes. However, educated speculations can be made based on the chemical properties of a substituted amino acid, whether it falls within any of the protein’s ...
... necessitates willingness to accept that firm conclusions cannot be drawn about the exact nature of any functional significance of amino acid changes. However, educated speculations can be made based on the chemical properties of a substituted amino acid, whether it falls within any of the protein’s ...
X-Linked Dominant Control of F-Cells in Normal
... some has not been determined. In healthy Japanese adults, far ...
... some has not been determined. In healthy Japanese adults, far ...
novel nucleotide carrier proteins of Protochlamydia
... general the obligate intracellular lifestyle correlates with a drastically reduced genome of the bacteria, typically showing defects in essential biosynthetic pathways (Moran, 2002) and compensatory transport mechanisms for the import of key metabolites from the host cytosol (Moulder, 1991). For exa ...
... general the obligate intracellular lifestyle correlates with a drastically reduced genome of the bacteria, typically showing defects in essential biosynthetic pathways (Moran, 2002) and compensatory transport mechanisms for the import of key metabolites from the host cytosol (Moulder, 1991). For exa ...
exploring genetics - Cold Spring Harbor Laboratory
... designed with you in mind. Our team of university scientists, middle grades classroom teachers, middle school students, and museum educators developed and tested the activities in a school setting. The activities are easily implemented and follow the North Carolina Standard Course of Study in both a ...
... designed with you in mind. Our team of university scientists, middle grades classroom teachers, middle school students, and museum educators developed and tested the activities in a school setting. The activities are easily implemented and follow the North Carolina Standard Course of Study in both a ...
Role of virulence factors, cell components and adhesion in
... other investigators who did not ¢nd di¡erences in iNOS induction using either epithelial cells [18] or murine macrophages [19] when cagA-positive and -negative strains were compared in stimulation assays. To gain further insight into other mechanisms that might be involved in iNOS upregulation, we m ...
... other investigators who did not ¢nd di¡erences in iNOS induction using either epithelial cells [18] or murine macrophages [19] when cagA-positive and -negative strains were compared in stimulation assays. To gain further insight into other mechanisms that might be involved in iNOS upregulation, we m ...
Pax6 lights-up the way for eye development Ruth Ashery
... Eye development in vertebrates has been an excellent model system to investigate fundamental processes in developmental biology from tissue induction to the formation of highly specialized structures such as the lens and the retina. This complex optic system develops primarily from three embryonic p ...
... Eye development in vertebrates has been an excellent model system to investigate fundamental processes in developmental biology from tissue induction to the formation of highly specialized structures such as the lens and the retina. This complex optic system develops primarily from three embryonic p ...
Bundle sheath suberization in grass leaves
... lamellae constrict the aperture of the pore (Haas and Carothers, 1975). Following SL development, a tertiary wall forms asymmetrically (State III). The tertiary wall is then enriched with lignin with the thickest region lying on the inner tangential wall in a characteristic “U-shape” (State IV; van ...
... lamellae constrict the aperture of the pore (Haas and Carothers, 1975). Following SL development, a tertiary wall forms asymmetrically (State III). The tertiary wall is then enriched with lignin with the thickest region lying on the inner tangential wall in a characteristic “U-shape” (State IV; van ...
Gene Section BAX (BCL2-associated X protein) Atlas of Genetics and Cytogenetics
... Colorectal cancer, T-cell acute lymphoblastic leukemia, chronic lymphocytic leukemia (CLL), B cell chronic lymphocytic leukemia, osteomyelitis. Prognosis BAX mutations have been found to be associated with positive prognosis in Dukes B2 patients, concerning survival. The G(-248)A polymorphism in the ...
... Colorectal cancer, T-cell acute lymphoblastic leukemia, chronic lymphocytic leukemia (CLL), B cell chronic lymphocytic leukemia, osteomyelitis. Prognosis BAX mutations have been found to be associated with positive prognosis in Dukes B2 patients, concerning survival. The G(-248)A polymorphism in the ...
Intracellular killing of bacteria: is Dictyostelium a model macrophage
... killing mechanisms. It is possible that combining alyA knockout with other mutations will reveal better its specific role in bacterial killing. Cathepsins are another important group of lysosomal hydrolases involved in protein degradation and recycling, and playing a role in several physiological pr ...
... killing mechanisms. It is possible that combining alyA knockout with other mutations will reveal better its specific role in bacterial killing. Cathepsins are another important group of lysosomal hydrolases involved in protein degradation and recycling, and playing a role in several physiological pr ...
Myeloid Leukemias - Current and Future Approaches to Targeted
... from hematopoietic progenitor or stem cells that acquire genetic defects which in turn lead to decreased or abnormal cell maturation, increased growth and survival. The survival advantage conferred by these genetic changes allow leukemic cells the ability to replace normal bone marrow and peripheral ...
... from hematopoietic progenitor or stem cells that acquire genetic defects which in turn lead to decreased or abnormal cell maturation, increased growth and survival. The survival advantage conferred by these genetic changes allow leukemic cells the ability to replace normal bone marrow and peripheral ...
The genetics of deafness - Archives of Disease in Childhood
... type II" have been 'mapped' to the long arms of chromosomes 2 and 1 respectively. Now that the responsible genes have been roughly localised, they will in due course be cloned and their protein products become available for ...
... type II" have been 'mapped' to the long arms of chromosomes 2 and 1 respectively. Now that the responsible genes have been roughly localised, they will in due course be cloned and their protein products become available for ...
The pruned gene encodes the Drosophila serum response factor and regulates cytoplasmic outgrowth during terminal branching of the tracheal system. Development 122, 1353-1362. pdf
... number of angiogenic factors have been identified in cell culture assays, such as acidic and basic fibroblast growth factors and vascular endothelial growth factor (Folkman and Shing, 1992). It is not yet known how these signaling molecules are involved in angiogenesis in vivo or how such signals ar ...
... number of angiogenic factors have been identified in cell culture assays, such as acidic and basic fibroblast growth factors and vascular endothelial growth factor (Folkman and Shing, 1992). It is not yet known how these signaling molecules are involved in angiogenesis in vivo or how such signals ar ...
Handbook on Sickle Cell Disease - English
... Pradesh, Kerala, Karnataka, Tamil Nadu and some Northeastern states. Initial screening for sickle cell allele across the state of Chhattisgarh has revealed that its prevalence as 10% in Chhattisgarh population. In some communities, the prevalence of the sickle cell allele is as high as 30%. Although ...
... Pradesh, Kerala, Karnataka, Tamil Nadu and some Northeastern states. Initial screening for sickle cell allele across the state of Chhattisgarh has revealed that its prevalence as 10% in Chhattisgarh population. In some communities, the prevalence of the sickle cell allele is as high as 30%. Although ...
Genetic and Molecular Diagnostics – Next Generation Sequencing
... these genes will result in an entire panel to be denied. These excluded genes are listed in Table 2. ii. Unless indicated otherwise, genetic testing panels which include any of the gene components in Table 2 are denied as statutorily excluded and not medically necessary tests under the MolDX Program ...
... these genes will result in an entire panel to be denied. These excluded genes are listed in Table 2. ii. Unless indicated otherwise, genetic testing panels which include any of the gene components in Table 2 are denied as statutorily excluded and not medically necessary tests under the MolDX Program ...
A Maize Glutaredoxin Gene, Abphyl2, Regulates
... maxima in Abph2 mutant meristems, compared with one maximum in the wild type (Figures 1E and 1F). Abph2 mutants also had dramatically enlarged SAMs; for example, in embryos 26 d after pollination (DAP), meristem width in Abph2 (185 6 5 mm, n = 10) was nearly 2-fold that of the wild type (96 6 12 mm, ...
... maxima in Abph2 mutant meristems, compared with one maximum in the wild type (Figures 1E and 1F). Abph2 mutants also had dramatically enlarged SAMs; for example, in embryos 26 d after pollination (DAP), meristem width in Abph2 (185 6 5 mm, n = 10) was nearly 2-fold that of the wild type (96 6 12 mm, ...
- eScholarship@UMMS - University of Massachusetts
... fibroblast cell lines were used in this study: an HGPS patient fibroblast (HGPS), a normal cell line from the father of the HGPS patient (Father), and an age-matched normal fibroblast line (Age Control). Two biological replicates were performed at different passages, since some changes in HGPS may p ...
... fibroblast cell lines were used in this study: an HGPS patient fibroblast (HGPS), a normal cell line from the father of the HGPS patient (Father), and an age-matched normal fibroblast line (Age Control). Two biological replicates were performed at different passages, since some changes in HGPS may p ...