and GvpD-mediated transcription regulation of the p
... The transcription of the 14 p-gvp genes involved in gas vesicle formation of Halobacterium salinarum PHH1 is driven by the four promoters pA, pD, pF and pO. The regulation of these promoters was investigated in Haloferax volcanii transformants with respect to the endogenous regulatory proteins GvpE ...
... The transcription of the 14 p-gvp genes involved in gas vesicle formation of Halobacterium salinarum PHH1 is driven by the four promoters pA, pD, pF and pO. The regulation of these promoters was investigated in Haloferax volcanii transformants with respect to the endogenous regulatory proteins GvpE ...
ch 11_4
... frequency of crossing-over between genes during meiosis might be a clue to the genes’ locations. Sturtevant reasoned that the farther apart two genes were on a chromosome, the more likely it would be that a crossover event would occur between them. If two genes are close together, then crossovers be ...
... frequency of crossing-over between genes during meiosis might be a clue to the genes’ locations. Sturtevant reasoned that the farther apart two genes were on a chromosome, the more likely it would be that a crossover event would occur between them. If two genes are close together, then crossovers be ...
Review Article
... infant mouse model of infection. Aside from establishing the importance of certain individual virulence factors in pathogenicity, this work identified a pleiotropically negative avirulent phenotype, designated Vir-, where a single Tn5 insertion prevented the expression of multiple virulence factors, ...
... infant mouse model of infection. Aside from establishing the importance of certain individual virulence factors in pathogenicity, this work identified a pleiotropically negative avirulent phenotype, designated Vir-, where a single Tn5 insertion prevented the expression of multiple virulence factors, ...
Meiosis I - scecinascience
... frequency of crossing-over between genes during meiosis might be a clue to the genes’ locations. Sturtevant reasoned that the farther apart two genes were on a chromosome, the more likely it would be that a crossover event would occur between them. If two genes are close together, then crossovers be ...
... frequency of crossing-over between genes during meiosis might be a clue to the genes’ locations. Sturtevant reasoned that the farther apart two genes were on a chromosome, the more likely it would be that a crossover event would occur between them. If two genes are close together, then crossovers be ...
Collaborative coupling between polymerase and helicase for
... separate activities at high forces or low dNTP concentration. We propose a collaborative model in which the helicase releases the fork regression pressure on the holoenzyme allowing it to adopt a processive polymerization conformation and the holoenzyme destabilizes the first few base pairs of the f ...
... separate activities at high forces or low dNTP concentration. We propose a collaborative model in which the helicase releases the fork regression pressure on the holoenzyme allowing it to adopt a processive polymerization conformation and the holoenzyme destabilizes the first few base pairs of the f ...
Comparative Analysis of Structural Diversity and
... clear genes. Pearson’s correlation test was used to determine if there is any significant correlation between Ks and GC3s or Ks and ENC. The statistically significant level was set at 95%. The statistical analyses were conducted using the program R (http://www.r-project.org/). Results and Discussion ...
... clear genes. Pearson’s correlation test was used to determine if there is any significant correlation between Ks and GC3s or Ks and ENC. The statistically significant level was set at 95%. The statistical analyses were conducted using the program R (http://www.r-project.org/). Results and Discussion ...
Mitochondrial DNA (mtDNA) Biogenesis: Visualization and Duel
... and Mitchison 2008). In addition, the labeling procedure for EdU does not involve the harsh acid or enzyme digests needed for BrdU epitope recovery, and therefore allows greater flexibility and more comprehensive results by comparing its incorporation with that of other intracellular markers (Cappel ...
... and Mitchison 2008). In addition, the labeling procedure for EdU does not involve the harsh acid or enzyme digests needed for BrdU epitope recovery, and therefore allows greater flexibility and more comprehensive results by comparing its incorporation with that of other intracellular markers (Cappel ...
Integrated genome sequence and linkage map of physic nut
... generated in this work is similar to that reported by Hirakawa et al. (2012) (298 Mbp). However, the mean scaffold length (>100 bp) and the N50 in this study are 13 861 bp and 0.746 Mbp, respectively, which are approximately 1.8 and 46.8 times longer, respectively, than the reported physic nut genom ...
... generated in this work is similar to that reported by Hirakawa et al. (2012) (298 Mbp). However, the mean scaffold length (>100 bp) and the N50 in this study are 13 861 bp and 0.746 Mbp, respectively, which are approximately 1.8 and 46.8 times longer, respectively, than the reported physic nut genom ...
Horizontal transfer of non-LTR retrotransposons: artifact or rare event
... can greatly expand opportunities to observe the distribution and evolutionary history of non-LTR retrotransposons in various eukaryotic taxa and to identify novel cases of HT. The most suitable eukaryotic group for such investigations proved to be Fungi. More than 100 fungal genomes are available fo ...
... can greatly expand opportunities to observe the distribution and evolutionary history of non-LTR retrotransposons in various eukaryotic taxa and to identify novel cases of HT. The most suitable eukaryotic group for such investigations proved to be Fungi. More than 100 fungal genomes are available fo ...
Cancer Prone Disease Section Retinoblastoma Atlas of Genetics and Cytogenetics
... of the RB1 gene are mutated (two-step inactivation mechanism typical of tumor suppressor genes). Nature and localization of individual mutations are heterogeneous regarding their nature: 20% deletions larger 1kb; 30% small deletions or insertions; 45% point mutations. And location: mutations have be ...
... of the RB1 gene are mutated (two-step inactivation mechanism typical of tumor suppressor genes). Nature and localization of individual mutations are heterogeneous regarding their nature: 20% deletions larger 1kb; 30% small deletions or insertions; 45% point mutations. And location: mutations have be ...
Evolution of Closely Linked Gene Pairs in
... However, close juxtaposition of 2 autonomous promoters does result in promoter cross talk (Hampf and Gossen 2007), unless an insulator is interposed (see e.g., Xie et al. 2007). It is therefore likely that the members of a closely linked h2h gene pair are no longer independently expressed. Indeed, m ...
... However, close juxtaposition of 2 autonomous promoters does result in promoter cross talk (Hampf and Gossen 2007), unless an insulator is interposed (see e.g., Xie et al. 2007). It is therefore likely that the members of a closely linked h2h gene pair are no longer independently expressed. Indeed, m ...
A viability-linked metagenomic analysis of
... the transfer of potential pathogenic organisms, be it via aerosols, fomites, surgical instruments, or medications. As human cycloviruses are frequently involved in disease [21], their observed presence in the cleanroom environment presents an unappreciated potential risk to human health in these typ ...
... the transfer of potential pathogenic organisms, be it via aerosols, fomites, surgical instruments, or medications. As human cycloviruses are frequently involved in disease [21], their observed presence in the cleanroom environment presents an unappreciated potential risk to human health in these typ ...
News from the west: Ancient DNA from a French megalithic burial
... a Paleolithic ancestry for modern Europeans. Nonetheless, two recent publications (Bramanti et al., 2009; Malmström et al., 2009) reported sequences from late European hunter-gatherers that demonstrated genetic differentiation between ancient hunter-gatherers, early Neolithic farmers, and modern Eu ...
... a Paleolithic ancestry for modern Europeans. Nonetheless, two recent publications (Bramanti et al., 2009; Malmström et al., 2009) reported sequences from late European hunter-gatherers that demonstrated genetic differentiation between ancient hunter-gatherers, early Neolithic farmers, and modern Eu ...
Possibilities and Limitations of Genetic Engineering
... the species of interest can by hybridized. The gene can come from another plant species, or from a non-plant species, such as a bacterium. In alfalfa, the most commonly used method of gene transfer is Agrobacterium tumefaciens mediated gene transfer. A. tumefaciens is a naturally occurring soil bact ...
... the species of interest can by hybridized. The gene can come from another plant species, or from a non-plant species, such as a bacterium. In alfalfa, the most commonly used method of gene transfer is Agrobacterium tumefaciens mediated gene transfer. A. tumefaciens is a naturally occurring soil bact ...
Myriad--Ambry -- Final Version of Ambry Preliminary Injunction
... sequence similarity with any particular gene requires an application of detailed knowledge from the discovery of that gene’s structure.2 A genetic variant is a change in the gene sequence. Any change, even one nucleotide, can constitute a variant. Some variants are harmless, but some—termed “mutatio ...
... sequence similarity with any particular gene requires an application of detailed knowledge from the discovery of that gene’s structure.2 A genetic variant is a change in the gene sequence. Any change, even one nucleotide, can constitute a variant. Some variants are harmless, but some—termed “mutatio ...
DNA breathing dynamics distinguish binding from nonbinding
... position of the restriction enzymes cleavage sites in the ssChIP assay are indicated at the top. The crystal structure of the YY1-P5 DNA complex (21) and the base-specific YY1 contacts on both strands (arrows) are shown below the diagram. The YY1 PWM is shown on the right. (B) Gel shift assays demons ...
... position of the restriction enzymes cleavage sites in the ssChIP assay are indicated at the top. The crystal structure of the YY1-P5 DNA complex (21) and the base-specific YY1 contacts on both strands (arrows) are shown below the diagram. The YY1 PWM is shown on the right. (B) Gel shift assays demons ...
Mutations affecting development of the zebrafish retina
... We inspected retinae of the mutant embryos at 3 dpf on histological sections. At this stage, wild-type retinal neurons form an easily recognizable pattern of nuclear and plexiform layers (Fig. 1C). In all three mutants the laminar arrangement of retinal neurons is disorganized (Fig. 3A-C). Instead o ...
... We inspected retinae of the mutant embryos at 3 dpf on histological sections. At this stage, wild-type retinal neurons form an easily recognizable pattern of nuclear and plexiform layers (Fig. 1C). In all three mutants the laminar arrangement of retinal neurons is disorganized (Fig. 3A-C). Instead o ...
Biotechnology/Cloning poster - SPARK: Scholarship at Parkland
... develop both patient and disease specific therapies for certain conditions. The procedure could also potentially use a patient’s own cells for tissue replacement. Although the science is exciting, it will likely take many decades of research before scientists are able to create transplantable tissu ...
... develop both patient and disease specific therapies for certain conditions. The procedure could also potentially use a patient’s own cells for tissue replacement. Although the science is exciting, it will likely take many decades of research before scientists are able to create transplantable tissu ...
CYP2B6 NESTED PCR: A GOOD APPROACH FOR PATIENTS ON METHADONE Original Article
... attributed primarily to the CYP3A4, CYP2B6, and CYP2D6 proteins in humans [2,9–12]. The detection of various single nucleotide polymorphisms (SNPs) involved in methadone action in vivo could help to identify an individual’s susceptibility to methadone toxicity and improve toxicological interpretatio ...
... attributed primarily to the CYP3A4, CYP2B6, and CYP2D6 proteins in humans [2,9–12]. The detection of various single nucleotide polymorphisms (SNPs) involved in methadone action in vivo could help to identify an individual’s susceptibility to methadone toxicity and improve toxicological interpretatio ...
Genetic tools for manipulating Acinetobacter baumannii genome: an
... carry a selectable marker, usually an antibiotic resistance gene. Sometimes integration vectors also contain oriT so that the construct can be transferred to other bacteria by conjugation. This is especially helpful when the other transfer methods, such as natural transformation or electroporation, ...
... carry a selectable marker, usually an antibiotic resistance gene. Sometimes integration vectors also contain oriT so that the construct can be transferred to other bacteria by conjugation. This is especially helpful when the other transfer methods, such as natural transformation or electroporation, ...
Regulation of Bacterial Conjugation in Microaerobiosis by
... (Camacho and Casadesus 2002, 2005). Post-transcriptional control of tra operon expression has been shown to involve the RNA chaperone Hfq (Will and Frost 2006), the GroEL heat-shock chaperone (Zahrl et al. 2007), and the extracytoplasmic stress CpxAR system (Gubbins et al. 2002; Zahrl et al. 2006; L ...
... (Camacho and Casadesus 2002, 2005). Post-transcriptional control of tra operon expression has been shown to involve the RNA chaperone Hfq (Will and Frost 2006), the GroEL heat-shock chaperone (Zahrl et al. 2007), and the extracytoplasmic stress CpxAR system (Gubbins et al. 2002; Zahrl et al. 2006; L ...
Leukaemia Section Atypical chronic myeloid leukemia (aCML) Atlas of Genetics and Cytogenetics
... been recurrently observed. Other abnormalities are: idic(Xq); del(5q); t(6;8)(p23;q22); -9; del(11q); del(12q); del(15q); del(17p); t(17;20) and add(21q). No specific cytogenetic changes have been associated with aCML. Recently a t(5;10)(q33;q22) has been described in a patient. ...
... been recurrently observed. Other abnormalities are: idic(Xq); del(5q); t(6;8)(p23;q22); -9; del(11q); del(12q); del(15q); del(17p); t(17;20) and add(21q). No specific cytogenetic changes have been associated with aCML. Recently a t(5;10)(q33;q22) has been described in a patient. ...
Hemoglobin A2: origin, evolution, and aftermath
... Current concepts of how the Lepore SP fusion gene variants produce the phenotype of thalassemia are that the Measurement of HbA,. The &chain of HbA, contains &globin gene sequences located at the 5’ portion of these two additional positive charges compared with the P-chain fusion genes result in the ...
... Current concepts of how the Lepore SP fusion gene variants produce the phenotype of thalassemia are that the Measurement of HbA,. The &chain of HbA, contains &globin gene sequences located at the 5’ portion of these two additional positive charges compared with the P-chain fusion genes result in the ...
Giraud-speciation-review-2010
... in novel host–pathogen combinations [17]. Horizontal gene transfer and inter-specific hybridization have been invoked to explain how pathogens might achieve an enhanced adaptive potential that allows the emergence of new fungal diseases on novel hosts [7], but such adaptation is usually the result o ...
... in novel host–pathogen combinations [17]. Horizontal gene transfer and inter-specific hybridization have been invoked to explain how pathogens might achieve an enhanced adaptive potential that allows the emergence of new fungal diseases on novel hosts [7], but such adaptation is usually the result o ...
Linking the emergence of fungal plant diseases with ecological
... in novel host–pathogen combinations [17]. Horizontal gene transfer and inter-specific hybridization have been invoked to explain how pathogens might achieve an enhanced adaptive potential that allows the emergence of new fungal diseases on novel hosts [7], but such adaptation is usually the result o ...
... in novel host–pathogen combinations [17]. Horizontal gene transfer and inter-specific hybridization have been invoked to explain how pathogens might achieve an enhanced adaptive potential that allows the emergence of new fungal diseases on novel hosts [7], but such adaptation is usually the result o ...