Two-Component System of Mycobacterium Tuberculosis
... MprAB TCS activates the SigE, which is one of the most studied sigma factors of Mycobacterium tuberculosis [55]. It contributes to maintaining basal expression levels of these genes during exponential growth. Moreover, MprA directly regulates acr2 and that the interactions of MprA with the acr2 prom ...
... MprAB TCS activates the SigE, which is one of the most studied sigma factors of Mycobacterium tuberculosis [55]. It contributes to maintaining basal expression levels of these genes during exponential growth. Moreover, MprA directly regulates acr2 and that the interactions of MprA with the acr2 prom ...
unit 20 inheritance and cell division
... inherited. But how does inheritance work? In what ways do offspring resemble their parents, and what causes such resemblances? As you also discovered in Unit 19, DNA plays a fundamental role in the lives of animals and plants. It can replicate, it is responsible for the synthesis of other chemicals ...
... inherited. But how does inheritance work? In what ways do offspring resemble their parents, and what causes such resemblances? As you also discovered in Unit 19, DNA plays a fundamental role in the lives of animals and plants. It can replicate, it is responsible for the synthesis of other chemicals ...
Model information sheet - EU
... E14 clone of embryonic stem cells was derived from mice of 129P2 substrain. (Hooper et al, 1987; Papaioanou and Johnson, 1993). Substrain 129S2 is widely used in gene targeting experiments because most of the available embryonic stem cell lines have been developed from strain 129S2. The D3 clone of ...
... E14 clone of embryonic stem cells was derived from mice of 129P2 substrain. (Hooper et al, 1987; Papaioanou and Johnson, 1993). Substrain 129S2 is widely used in gene targeting experiments because most of the available embryonic stem cell lines have been developed from strain 129S2. The D3 clone of ...
Slide - Gerstein Lab
... molecules (in the sense of physical-chemistry) and then applying “informatics” techniques (derived from disciplines such as applied math, CS, and statistics) to understand and organize the information associated with these molecules, on a large-scale. • Bioinformatics is a practical discipline with ...
... molecules (in the sense of physical-chemistry) and then applying “informatics” techniques (derived from disciplines such as applied math, CS, and statistics) to understand and organize the information associated with these molecules, on a large-scale. • Bioinformatics is a practical discipline with ...
Maintenance of genomic integrity by p53: complementary
... seems to be mainly required for the DNA damageinduced G1 arrest, as p21Waf1 clearly is not essential for the immediate G2 checkpoint response (Brugarolas et al., 1995; Levedakou et al., 1995; Paules et al., 1995). Nevertheless, several studies have suggested that the G2/M arrest following DNA damage ...
... seems to be mainly required for the DNA damageinduced G1 arrest, as p21Waf1 clearly is not essential for the immediate G2 checkpoint response (Brugarolas et al., 1995; Levedakou et al., 1995; Paules et al., 1995). Nevertheless, several studies have suggested that the G2/M arrest following DNA damage ...
Signal Transduction and the Chemically Addressed Nervous System
... unique brain chemicals. In this book, however, only a half dozen or so particular neurotransmitters are emphasized, because psychotropic drugs utilized in clinical practice act largely on serotonin, norepinephrine, and dopamine as well as acetylcholine, glutamate, and GABA (gamma-aminobutyric acid). ...
... unique brain chemicals. In this book, however, only a half dozen or so particular neurotransmitters are emphasized, because psychotropic drugs utilized in clinical practice act largely on serotonin, norepinephrine, and dopamine as well as acetylcholine, glutamate, and GABA (gamma-aminobutyric acid). ...
Charge Transport in DNA - Insights from
... experimental investigations are conducted under conditions not represented accurately in most theoretical approaches until now. A common feature of charge transport experiments is to attach the DNA strand to electrodes with varying distances. Moreover, single-molecule experiments are conducted in mo ...
... experimental investigations are conducted under conditions not represented accurately in most theoretical approaches until now. A common feature of charge transport experiments is to attach the DNA strand to electrodes with varying distances. Moreover, single-molecule experiments are conducted in mo ...
MCScanX`s manual
... homologous relationships detected by third party software. In this case, users should use MCScanX_h instead. The executation of MCScanX_h is very similar to that of MCScanX, except that the "xyz.blast" file should be replaced by "xyz.homology" file. At the bottom of screen output, statistics on numb ...
... homologous relationships detected by third party software. In this case, users should use MCScanX_h instead. The executation of MCScanX_h is very similar to that of MCScanX, except that the "xyz.blast" file should be replaced by "xyz.homology" file. At the bottom of screen output, statistics on numb ...
Analyses of 16S rRNA and RuBisCO large subunit genes from an
... His-291, Arg-292, His-324, Lys-331, and Leu332 were conserved in the current ORUs except Loihi-cbbL-4 and -5 in which some of these catalytic amino acid residues were replaced by conserved or dissimilar amino acid residues. Substitution of absolutely conserved catalytic amino acid residues by dissim ...
... His-291, Arg-292, His-324, Lys-331, and Leu332 were conserved in the current ORUs except Loihi-cbbL-4 and -5 in which some of these catalytic amino acid residues were replaced by conserved or dissimilar amino acid residues. Substitution of absolutely conserved catalytic amino acid residues by dissim ...
Sphingolipids and lysosomal pathologies - Limes-Institut-Bonn
... pathway by endolysosomal enzymes with the assistance of small lipid binding proteins [1]. Inherited metabolic defects in one of the steps lead to a block of degradation and accumulation of the corresponding substrates, resulting in a group of lysosomal storage diseases, the sphingolipidoses. Detaile ...
... pathway by endolysosomal enzymes with the assistance of small lipid binding proteins [1]. Inherited metabolic defects in one of the steps lead to a block of degradation and accumulation of the corresponding substrates, resulting in a group of lysosomal storage diseases, the sphingolipidoses. Detaile ...
Codon usage in the Mycobacterium tuberculosis corn
... although its genomic G C content is rather lower than in these other species (about 65 mol%, compared to about 75 mol YO). Second, M. tuberculosis multiplies almost exclusively in macrophages, with a doubling time of about 24 h : if codon selection were mediated by the need for efficient use of ribo ...
... although its genomic G C content is rather lower than in these other species (about 65 mol%, compared to about 75 mol YO). Second, M. tuberculosis multiplies almost exclusively in macrophages, with a doubling time of about 24 h : if codon selection were mediated by the need for efficient use of ribo ...
Introduction to Genetics
... female is XX genetic makeup. She must inherit two O genes to be a ginger cat. The O gene is called a sex-linked gene because it is carried on a sex chromosome. If the female cat inherits only one O gene, she will be tortoiseshell (heterozygous for red colour). The formation of red and black patches ...
... female is XX genetic makeup. She must inherit two O genes to be a ginger cat. The O gene is called a sex-linked gene because it is carried on a sex chromosome. If the female cat inherits only one O gene, she will be tortoiseshell (heterozygous for red colour). The formation of red and black patches ...
A genetic linkage map for watermelon based on
... in the temperate regions of Africa, central Asia, and the Mediterranean (Jeffrey, 1975; Whitaker and Bemis, 1976; Whitaker and Davis, 1962), and has a haploid genome size of 4.25 × 108 base pairs (bp) (Arumuganathan and Earle, 1991). The cultivated watermelon (2n = 2x = 22) (Shimotsuma, 1963) appear ...
... in the temperate regions of Africa, central Asia, and the Mediterranean (Jeffrey, 1975; Whitaker and Bemis, 1976; Whitaker and Davis, 1962), and has a haploid genome size of 4.25 × 108 base pairs (bp) (Arumuganathan and Earle, 1991). The cultivated watermelon (2n = 2x = 22) (Shimotsuma, 1963) appear ...
Journal of Biotechnology
... antibiotics share a common mode of synthesis, the multicarrier thiotemplate mechanism (Stein et al., 1996). They are biosynthesized by multi-modular proteins termed non-ribosomal peptide synthetases. Each elongation cycle in non-ribosomal peptide biosynthesis needs the cooperation of three basic dom ...
... antibiotics share a common mode of synthesis, the multicarrier thiotemplate mechanism (Stein et al., 1996). They are biosynthesized by multi-modular proteins termed non-ribosomal peptide synthetases. Each elongation cycle in non-ribosomal peptide biosynthesis needs the cooperation of three basic dom ...
Genetic recombination in plants
... 0 Current Biology Ltd ISSN 1369-5266 Abbreviation DSB double-strand break ...
... 0 Current Biology Ltd ISSN 1369-5266 Abbreviation DSB double-strand break ...
Chromosomal Mutations - Virtual Learning Environment
... These extra copies can undergo mutations to take on altered roles in the cell, or they can become pseudogenes, which are the inactive forms of the gene. Unequal crossing over happens during the prophase of meiosis one. Homologous chromosomes pair at this stage, and sometimes pairing occurs between t ...
... These extra copies can undergo mutations to take on altered roles in the cell, or they can become pseudogenes, which are the inactive forms of the gene. Unequal crossing over happens during the prophase of meiosis one. Homologous chromosomes pair at this stage, and sometimes pairing occurs between t ...
Exploring Genetics Across the Middle School Science
... University, which funded the development of this manual. Genetic scientists generate raw data through their research. They must work in collaboration with statisticians and computer scientists to process and analyze the data in order to draw conclusions. If students can grasp the overlap of the two ...
... University, which funded the development of this manual. Genetic scientists generate raw data through their research. They must work in collaboration with statisticians and computer scientists to process and analyze the data in order to draw conclusions. If students can grasp the overlap of the two ...
World of Microbiology and Immunology Vol 2
... capable of triggering an immune response. Although this list is not exhaustive, antigens can be derived from toxins, protein, carbohydrates, DNA, or other molecules from viruses, bacteria, cellular parasites, or cancer cells. The natural immune response will hold an infection at bay as the next line ...
... capable of triggering an immune response. Although this list is not exhaustive, antigens can be derived from toxins, protein, carbohydrates, DNA, or other molecules from viruses, bacteria, cellular parasites, or cancer cells. The natural immune response will hold an infection at bay as the next line ...
2- pcr primer design and reaction optimisation
... The specific complementary association due to hydrogen bonding of singlestranded nucleic acids is referred to as "annealing": two complementary sequences will form hydrogen bonds between their complementary bases (G to C, and A to T or U) and form a stable double-stranded, anti-parallel "hybrid" mol ...
... The specific complementary association due to hydrogen bonding of singlestranded nucleic acids is referred to as "annealing": two complementary sequences will form hydrogen bonds between their complementary bases (G to C, and A to T or U) and form a stable double-stranded, anti-parallel "hybrid" mol ...
Metabolomics based gene function annotation in Escherichia coli
... the growth and metabolic consequences of KASII and KASIII single and double mutants in E. coli are presented. The third chapter describes a functional genomics effort to develop a gene function annotation method. This method relied on metabolomics and NMR ligand binding assays to assign function to ...
... the growth and metabolic consequences of KASII and KASIII single and double mutants in E. coli are presented. The third chapter describes a functional genomics effort to develop a gene function annotation method. This method relied on metabolomics and NMR ligand binding assays to assign function to ...
Intelligent Icons: Integrating Lite-Weight Data Mining
... the substring AT appears 3 times in the first 30 base pairs of the human mitochondrial DNA, which is GATCACAGGTCTATCACCCTATTAACCACT. If we attempt this strategy, we must consider the best way to map the new features to our 32 by 32 bitmap. We could do this arbitrarily as before, for example we could ...
... the substring AT appears 3 times in the first 30 base pairs of the human mitochondrial DNA, which is GATCACAGGTCTATCACCCTATTAACCACT. If we attempt this strategy, we must consider the best way to map the new features to our 32 by 32 bitmap. We could do this arbitrarily as before, for example we could ...
An Introduction to RNA Interference (RNAi)
... To be sure, the discovery of RNAi comes at a good time. Less than five years after the sequencing of the human genome, genetic research is booming with a record number of potential drug targets being uncovered, all of which can theoretically be addressed through RNAi. An example of one such gene th ...
... To be sure, the discovery of RNAi comes at a good time. Less than five years after the sequencing of the human genome, genetic research is booming with a record number of potential drug targets being uncovered, all of which can theoretically be addressed through RNAi. An example of one such gene th ...
Joachim Denner, Ralf R. Tönjes. Infection Barriers to Successful
... that infection of humans with human immunodeficiency virus (HIV) and the AIDS pandemic were the result of a transspecies transmission of a retrovirus, simian immunodeficiency virus (SIV), to humans. Thus, the same potential was perceived for PERVs, because PERVs are also retroviruses; however, they ...
... that infection of humans with human immunodeficiency virus (HIV) and the AIDS pandemic were the result of a transspecies transmission of a retrovirus, simian immunodeficiency virus (SIV), to humans. Thus, the same potential was perceived for PERVs, because PERVs are also retroviruses; however, they ...
PHANTASTICA Regulates Development of the Adaxial Mesophyll in
... is shown in Figure 1 with identical residues shaded. All have a highly conserved MYB DNA binding domain at the N terminus, consisting of two imperfect repeats (55 and 51 residues), both of which are essential for sequence-specific DNA binding based on structural analysis of c-MYB (Jin and Martin, 19 ...
... is shown in Figure 1 with identical residues shaded. All have a highly conserved MYB DNA binding domain at the N terminus, consisting of two imperfect repeats (55 and 51 residues), both of which are essential for sequence-specific DNA binding based on structural analysis of c-MYB (Jin and Martin, 19 ...