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Genome Assembly and Annotation
Genome Assembly and Annotation

... – ~ 45% of the human genome consists of repeats interspersed with non-repetitive sequences • Transposon derived (LINEs, SINEs) • 3 – 4% segmental duplications (> 1kb, > 90% similar), ~ 40% believed to be misassembled • Multi-gene families ...
Gene Mapping using 3 Point Test Crosses: Outlined below are the
Gene Mapping using 3 Point Test Crosses: Outlined below are the

... 3) Determine which two groups belong in the DCO class. This information can then be used to determine the gene order. The gene order is determined by predicting the events resulting from a double cross over event. This is shown below. Try all three combinations, and make sure that you have the corre ...
800X400 pixel file here
800X400 pixel file here

... 1959 scientists discovered Down Syndrome was the result of an extra 21st chromosome. That means that much of the material you are studying has been discovered in your parent's lifetime. Since you are already aware that the genetic material in the nucleus is DNA, we can dispense with any lengthy expl ...
Honors Biology Unit Calendar Honors bio genetics-unit
Honors Biology Unit Calendar Honors bio genetics-unit

... Purpose: Now that you have background on how genes code for proteins, we can begin to study how genes influence traits. There will be many new vocabulary words, but the subject is fascinating and gives reasons for why organisms are the way they are. The field is related to the study of many diseases ...
The Moss Physcomitrella patens, a Model System
The Moss Physcomitrella patens, a Model System

... through a surface water film and down the neck of the archegonia. The zygote develops into a diploid sporophyte that in Physcomitrella is small, consisting of a short stalk a few millimeters long that bears a spore capsule -2 mm in diameter. Spore capsules have no specialized structuresfor dehiscenc ...
Mei-S332, a Drosophila Protein Required for Sister
Mei-S332, a Drosophila Protein Required for Sister

... Northern blot analysis both confirmed that the transcription unit within the 4.2 kb genomic region is that of the mei-S332 gene and revealed that there are sex-specific forms of the transcript. There are three testis transcripts of 1.55, 1.6, and 1.8 kb as well as a single 1.75 kb ovary transcript ( ...
autosomal inheritance
autosomal inheritance

... phenotypic splitting relation corresponds with genotypic splitting relation (1:2:1). ...
DNA barcoding: how it complements taxonomy, molecular
DNA barcoding: how it complements taxonomy, molecular

... usability and robustness of COI in a standard highthroughput barcoding analysis have been extensively assessed [16]. Other researchers have suggested that alternate loci might also serve as a basis for species identification. For example, 18S rDNA has been used for the identification of soil nematod ...
Gene Section FHIT (fragile histidine triad) Atlas of Genetics and Cytogenetics
Gene Section FHIT (fragile histidine triad) Atlas of Genetics and Cytogenetics

... enzyme-substrate complex appears to be the tumor suppressor signal. Restoration of Fhit expression in Fhit-deficient cancer cells causes death by apoptosis, involving the intrinsic caspase pathway, in cancerderived cells and in tumor xenografts. ...
Untitled Document Name: Date: 1. The picture below shows
Untitled Document Name: Date: 1. The picture below shows

... Which statement describes the primary advantage of sexual reproduction over asexual reproduction? A. ...
Slides
Slides

... •  Now we have groups of genes that best fit their annotation, find the best annotation(s) that fits those groups. ...
What is Sickle Cell Disease?
What is Sickle Cell Disease?

... Strokes are a blockage of blood flow to a part of the brain caused by the sickle cells. The symptoms include one sided weakness, numb feelings, seizures, slurred speech or facial weakness. Treatment is with chronic transfusion to maintain the Hb S level at less than 30% to prevent recurrences or eve ...
What is Sickle Cell Disease?
What is Sickle Cell Disease?

... Strokes are a blockage of blood flow to a part of the brain caused by the sickle cells. The symptoms include one sided weakness, numb feelings, seizures, slurred speech or facial weakness. Treatment is with chronic transfusion to maintain the Hb S level at less than 30% to prevent recurrences or eve ...
Extended Phenotype – But Not Too Extended
Extended Phenotype – But Not Too Extended

... speculation need not worry us at this stage. The point is to be precise about the genetic nature of the speculation. Adaptive hypotheses, however wild and speculative, must not be vaguely Panglossian but precisely limited to specified alleles (or other replicators) which vary and which exert a causa ...
Embryo and Endosperm Inherit Distinct Chromatin
Embryo and Endosperm Inherit Distinct Chromatin

... 1B). This was particularly evident at the one-cell embryo stage (Figures 1A and 1B), where the number of endosperm nuclei was less than half of the wild-type count. We interpreted these phenotypes as resulting from partial downregulation of transcriptional activity. Our results indicate that levels ...
The coordination of ploidy and cell size differs
The coordination of ploidy and cell size differs

... mesophyll cells, a novel technique that renders tissues transparent was developed to avoid scattering light and autofluorescence from cell walls and chloroplasts by treating the samples with 2,2′thiodiethanol after fixation (Fig. 1D,E). This new optical technique enabled deep imaging using normal co ...
Bio Frames - Lee County School District
Bio Frames - Lee County School District

... Define a problem based on a specific body of knowledge for example: biology, chemistry, physics, and earth/space science and do the following: (DOK High) (1) pose quesons about the natural world, (2) conduct systemic observa ons, (3) examine books and other sources of informa on to see what is already ...
Slide 1
Slide 1

... The mutations in the cot1 gene can results in compact morphologies ...
Terauchi, R., Abe, A., Takagi, H., Tamiru, M
Terauchi, R., Abe, A., Takagi, H., Tamiru, M

... The first is applied to progeny derived from a cross between known parents; therefore, it is most widely used for gene isolation from crop species that are amenable to artificial crossing. Typically, crossing of two inbred parental lines results in F1, which is self-fertilized to generate F2 progeny ...
Transcription Translation 2017 p2.notebook
Transcription Translation 2017 p2.notebook

... A. Goal: Take a gene from DNA and make a mRNA copy B. Location: Nucleus (eukaryotic cell) C. Steps to Transcription: 1. Initiation: RNA Polymerase binds to the promoter          (start sequence) of a gene on a DNA strand 2. Elongation:  RNA Polymerase build a new RNA      strand off the template str ...
16_Lecture_Presentation
16_Lecture_Presentation

... inactivate the 3 likely “agents of transformation” – RNA -they added Rnase to inactivate it ...
Processes for producing lactic acid using yeast transformed with a
Processes for producing lactic acid using yeast transformed with a

... metabolic activities of the producing microorganism. Besides the presence of lactic acid, loWering the pH value also inhibits cell groWth and metabolic activity. As a result, the extent of lactic acid production is greatly reduced. Therefore, the addition of Ca(OH)2, CaCO3, NaOH, or NH4OH to neutral ...
Nucleotide Sequence of the SAC2 Gene of Saccharomyces cerevisiae .
Nucleotide Sequence of the SAC2 Gene of Saccharomyces cerevisiae .

... (1974). Cold-sensitivity of sac mutants was as- Sequencing of the SAC2 gene sessed at 11, 14 and 16°C.Plates were incubated up The 3.8 kb EcoRV-SalI fragment was subcloned to 10 days at 11°C. Temperature-sensitivity of into M13 derivatives (Messing, 1983) and seactl-1 and suppression by SAC2 mutatio ...
Read the first chapter
Read the first chapter

... An exact determination of the laws of heredity will probably work more change in man’s outlook on the world, and in his power over nature, than any other advance in natural knowledge that can be foreseen. —William Bateson ...
Cells
Cells

... The shape of a cell is related to its function. Where do you see this idea in sport? Why are the players in a rugby team often different shapes and sizes? The players in a rugby team are different shapes and sizes because each player does a different job for the team. Like rugby players, cells are d ...
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Vectors in gene therapy

Gene therapy utilizes the delivery of DNA into cells, which can be accomplished by several methods, summarized below. The two major classes of methods are those that use recombinant viruses (sometimes called biological nanoparticles or viral vectors) and those that use naked DNA or DNA complexes (non-viral methods).
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