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Gene Ontology (GO) Tutorial
... Occasionally, one will come across gene products that have been annotated to Process, Function, and/or Component Unknown. These three terms are used when a curator has looked over the available literature and has found that none of it is adequate to assign a term. A good example is Dab2ip. As shown ...
... Occasionally, one will come across gene products that have been annotated to Process, Function, and/or Component Unknown. These three terms are used when a curator has looked over the available literature and has found that none of it is adequate to assign a term. A good example is Dab2ip. As shown ...
Sickle cell anemia, thalassemia, and congenital hemolytic
... group of 2048 control children in Ghana. In this study, AC was only associated with a decrease in cerebral malaria. Although AS is clearly protective against severe malaria, it is not known how sickle hemoglobin provides this protection. There are several mechanisms that could account for the protec ...
... group of 2048 control children in Ghana. In this study, AC was only associated with a decrease in cerebral malaria. Although AS is clearly protective against severe malaria, it is not known how sickle hemoglobin provides this protection. There are several mechanisms that could account for the protec ...
Antibiotic susceptibility pattern among Staphylococcus spp. with
... means isolates with MIC≥512µg/ml harbor a high copy number of mecA genes and regulatory elements (4,17). For achieving this hypothesis, all PCR tests were performed using same amount of template DNA and with similar concentration. It may also be due to the availability of sites of DNA amplification. ...
... means isolates with MIC≥512µg/ml harbor a high copy number of mecA genes and regulatory elements (4,17). For achieving this hypothesis, all PCR tests were performed using same amount of template DNA and with similar concentration. It may also be due to the availability of sites of DNA amplification. ...
The role of Pax-1 in axial skeleton development
... boundaries. By cell labelling experiments it has been shown that one vertebral body is derived from cells originating from two adjacent somites (Bagnall, 1992; Ewan and Everett, 1992). The mechanisms that control these morphological events in axial and lateral regions have not been studied, however. ...
... boundaries. By cell labelling experiments it has been shown that one vertebral body is derived from cells originating from two adjacent somites (Bagnall, 1992; Ewan and Everett, 1992). The mechanisms that control these morphological events in axial and lateral regions have not been studied, however. ...
antiviral drugs – aspects of clinical use and recent advances
... antiviral therapy in such cases. Peginterferon-ribavirin combination therapy is known to have limited efficacy in decompensated cirrhotics.4,5 Also, compared to non-cirrhotics, such patients are more prone to develop hematologic side effects (neutropenia, thrombocytopenia & anemia) with antiviral th ...
... antiviral therapy in such cases. Peginterferon-ribavirin combination therapy is known to have limited efficacy in decompensated cirrhotics.4,5 Also, compared to non-cirrhotics, such patients are more prone to develop hematologic side effects (neutropenia, thrombocytopenia & anemia) with antiviral th ...
Red cell pyruvate kinase deficiency: molecular and clinical aspects
... the product pyruvate are involved in a number of energetic and biosynthetic pathways and the tight regulation of PK activity has been shown to be of great importance not only for glycolysis itself, but also for the entire cellular metabolism. Thus, one of the main features of this enzyme is its allo ...
... the product pyruvate are involved in a number of energetic and biosynthetic pathways and the tight regulation of PK activity has been shown to be of great importance not only for glycolysis itself, but also for the entire cellular metabolism. Thus, one of the main features of this enzyme is its allo ...
Tandem Genetic Duplications in Phage and Bacteria
... of a RDH constitutive strain, using xylitol as the sole carbon source, has yielded evolved strains that utilize xylitol much faster. The increased fitness exhibited by these strains appears to be due to quantitative increases in RDH activity. In all cases, the increased activity was due to duplicati ...
... of a RDH constitutive strain, using xylitol as the sole carbon source, has yielded evolved strains that utilize xylitol much faster. The increased fitness exhibited by these strains appears to be due to quantitative increases in RDH activity. In all cases, the increased activity was due to duplicati ...
PHARMACOLOGICAL APPROACHES TO TREAT VIRAL
... establishing the right diagnosis, isolation and studying viruses. However, in recent years, with the advancement in molecular technique, discovery of highly sensitive and specific viral quantitative method, more antiviral agents are available for the treatment of these diseases. ...
... establishing the right diagnosis, isolation and studying viruses. However, in recent years, with the advancement in molecular technique, discovery of highly sensitive and specific viral quantitative method, more antiviral agents are available for the treatment of these diseases. ...
Preview the material
... establishing the right diagnosis, isolation and studying viruses. However, in recent years, with the advancement in molecular technique, discovery of highly sensitive and specific viral quantitative method, more antiviral agents are available for the treatment of these diseases. ...
... establishing the right diagnosis, isolation and studying viruses. However, in recent years, with the advancement in molecular technique, discovery of highly sensitive and specific viral quantitative method, more antiviral agents are available for the treatment of these diseases. ...
SHY2/IAA3 regulates root development
... demonstrated to be IAA17 (Rouse et al., 1998). shy2 and axr3 mutants share several phenotypes, such as short hypocotyls, curled-up leaves and leaf formation in darkness. However, unlike shy2 mutants, axr3 mutants have few shoot branches and highly agravitropic roots that lack root hairs (Leyser et a ...
... demonstrated to be IAA17 (Rouse et al., 1998). shy2 and axr3 mutants share several phenotypes, such as short hypocotyls, curled-up leaves and leaf formation in darkness. However, unlike shy2 mutants, axr3 mutants have few shoot branches and highly agravitropic roots that lack root hairs (Leyser et a ...
Plant speciation through chromosome instability and ploidy change
... Multivalent: Physical linkage of three or more chromosomes at the meiotic diakinesis-metaphase I stages through establishment of genetic cross-overs or chiasmata. Neo-functionalization: The acquisition of novel function in one of a pair of genes resulting from a gene or a whole genome duplication ev ...
... Multivalent: Physical linkage of three or more chromosomes at the meiotic diakinesis-metaphase I stages through establishment of genetic cross-overs or chiasmata. Neo-functionalization: The acquisition of novel function in one of a pair of genes resulting from a gene or a whole genome duplication ev ...
Unit II presentation
... • Also presents as neonatal jaundice anaemia Chronic non-spherocytic haemolytic anaemia • The precise mechanism by which increased sensitivity to oxidative damage leads to haemolysis is not fully known. • The sequence of events after an exogenous trigger factor is present is also unknown ...
... • Also presents as neonatal jaundice anaemia Chronic non-spherocytic haemolytic anaemia • The precise mechanism by which increased sensitivity to oxidative damage leads to haemolysis is not fully known. • The sequence of events after an exogenous trigger factor is present is also unknown ...
Study Guide from DOE
... A student wants to determine the effect of a certain brand of liquid fertilizer on the growth of ivy. Ivy plants of the same length are planted in the same amount of soil in three identical containers. To one container, 5 mL of fertilizer is added: in the second container, 10 mL of the fertilizer i ...
... A student wants to determine the effect of a certain brand of liquid fertilizer on the growth of ivy. Ivy plants of the same length are planted in the same amount of soil in three identical containers. To one container, 5 mL of fertilizer is added: in the second container, 10 mL of the fertilizer i ...
Taurine 10 sample chapter
... to isolate the pancreas without the surrounding adipose tissue of the peritoneum. Each pancreas yielded approximately 150 sections. Quantification of the number of islets was based on determining the number of islets per section. Histological examination of pancreas from taurine-fed mice revealed a ...
... to isolate the pancreas without the surrounding adipose tissue of the peritoneum. Each pancreas yielded approximately 150 sections. Quantification of the number of islets was based on determining the number of islets per section. Histological examination of pancreas from taurine-fed mice revealed a ...
SOD is an enzyme with four different types of metal
... SOD is an enzyme with four different types of metal ions, dividing this family into Cu,Zn-, Fe-, Mn- and Ni-SODs. About 2 billion years ago during the oxygenation of biosphere the evolution of SOD and other antioxidant enzymes was probably triggered by production of O2 by photosynthetic organisms. ...
... SOD is an enzyme with four different types of metal ions, dividing this family into Cu,Zn-, Fe-, Mn- and Ni-SODs. About 2 billion years ago during the oxygenation of biosphere the evolution of SOD and other antioxidant enzymes was probably triggered by production of O2 by photosynthetic organisms. ...
Gene Section CYP2A6 (cytochrome P450, family 2, subfamily A, polypeptide 6)
... CYP2A6 is an enzyme responsible for the metabolism of clinically used pharmaceuticals such as coumarin and valproic acid, several carcinogens such as 4(methylnitrosamine)-1-(3-pyridyl)-1-butanone and aflatoxin B1, nicotine and for the bioactivation process of tegafur to 5-FU. The formation of 5-FU f ...
... CYP2A6 is an enzyme responsible for the metabolism of clinically used pharmaceuticals such as coumarin and valproic acid, several carcinogens such as 4(methylnitrosamine)-1-(3-pyridyl)-1-butanone and aflatoxin B1, nicotine and for the bioactivation process of tegafur to 5-FU. The formation of 5-FU f ...
Getting Started With Gel Electrophoresis
... TBE buffer is supplied as a 20x concentrate. Prepare diluted (1x) working solutions as required. Re-dissolve any solids that precipitate out during storage by heating in a water bath. SCIENCE: The composition of this buffer is designed to keep the pH slightly alkaline. This ensures that the DNA mole ...
... TBE buffer is supplied as a 20x concentrate. Prepare diluted (1x) working solutions as required. Re-dissolve any solids that precipitate out during storage by heating in a water bath. SCIENCE: The composition of this buffer is designed to keep the pH slightly alkaline. This ensures that the DNA mole ...
Unveiling the physiological and molecular basis of Mycobacterium
... The Mycobacterium tuberculosis complex (MTC) includes several closely-related pathogenic species, namely M. tuberculosis, the main etiological agent of human tuberculosis (TB), and M. bovis, the causative agent of bovine tuberculosis (bTB), one of the most relevant zoonosis in the world. The complex ...
... The Mycobacterium tuberculosis complex (MTC) includes several closely-related pathogenic species, namely M. tuberculosis, the main etiological agent of human tuberculosis (TB), and M. bovis, the causative agent of bovine tuberculosis (bTB), one of the most relevant zoonosis in the world. The complex ...
World Index of BioMolecular Visualization Resources
... sizes proportional to the atomic, ionic and van der Waals radii. The different neutral and ionic states are presented on different planes. The site is designed to be viewed with Chime and there is also a set of buttons to create displays of only particular planes, elements, groups, periods, and colo ...
... sizes proportional to the atomic, ionic and van der Waals radii. The different neutral and ionic states are presented on different planes. The site is designed to be viewed with Chime and there is also a set of buttons to create displays of only particular planes, elements, groups, periods, and colo ...
Regulation of Ovule Development
... the focus of classic and molecular genetic analyses in recent years. This has been an exciting time to be involved in plant developmental biology, because many genetic pathways and regulatory mechanisms have been elucidated. Continued studies of ovule mutants have contributed to and benefited from t ...
... the focus of classic and molecular genetic analyses in recent years. This has been an exciting time to be involved in plant developmental biology, because many genetic pathways and regulatory mechanisms have been elucidated. Continued studies of ovule mutants have contributed to and benefited from t ...
NEET-2017 Solved Paper
... Thalassemia and sickle cell anemia are caused due to a problem in globin molecules synthesis. Select the CORRECT statement. (1) Both are due to a qualitative defect in globin chain synthesis. (2) Both are due to a quantitative defect in globin chain synthesis. (3) Thalassemia is due to less synthesi ...
... Thalassemia and sickle cell anemia are caused due to a problem in globin molecules synthesis. Select the CORRECT statement. (1) Both are due to a qualitative defect in globin chain synthesis. (2) Both are due to a quantitative defect in globin chain synthesis. (3) Thalassemia is due to less synthesi ...
Full Text - Universiteit Leiden
... through fetal and then postnatal life (4) (Figure 1.2). Furthermore with respect to hemoglobin expression there are also two main switches during prenatal development. The first switch from embryonic-to-fetal hemoglobin expression takes place early in gestation. The second from fetal-to-postnatal he ...
... through fetal and then postnatal life (4) (Figure 1.2). Furthermore with respect to hemoglobin expression there are also two main switches during prenatal development. The first switch from embryonic-to-fetal hemoglobin expression takes place early in gestation. The second from fetal-to-postnatal he ...
Genotype C of hepatitis B virus can be classified into at least two
... southern end of Japan) and two from China. Two databasederived isolates found in Australian Aborigines and New Caledonia formed an outgroup of the genotype. Phylogenetic analysis based on full genomic sequences of 10 HBV isolates from Vietnam (3), Myanmar (3), Thailand (2) and Okinawa (2) also confi ...
... southern end of Japan) and two from China. Two databasederived isolates found in Australian Aborigines and New Caledonia formed an outgroup of the genotype. Phylogenetic analysis based on full genomic sequences of 10 HBV isolates from Vietnam (3), Myanmar (3), Thailand (2) and Okinawa (2) also confi ...
mic.sgmjournals.org
... (cg2120), with primers Fruca-1 and Fruca-2 (plasmid pAG1032) and the chromosomal fruR gene (cg2118) with primers FruR-1 and FruR-2 (plasmid pAG1035). As fruR is the first cistron of the cg2118-cg2119cg2120 operon (Gaigalat et al., 2007), the orientation of the fruR fragment in pAG1035 was chosen in ...
... (cg2120), with primers Fruca-1 and Fruca-2 (plasmid pAG1032) and the chromosomal fruR gene (cg2118) with primers FruR-1 and FruR-2 (plasmid pAG1035). As fruR is the first cistron of the cg2118-cg2119cg2120 operon (Gaigalat et al., 2007), the orientation of the fruR fragment in pAG1035 was chosen in ...
Premature stop codons involved in muscular dystrophies
... in which a given mutation is embedded in a unique nucleotide context, and differs between patients. Several reasons indicated an investigation of gentamicin: its effect on readthrough is the best documented to date, and it is known to present a much lower toxicity than other suppressive molecules li ...
... in which a given mutation is embedded in a unique nucleotide context, and differs between patients. Several reasons indicated an investigation of gentamicin: its effect on readthrough is the best documented to date, and it is known to present a much lower toxicity than other suppressive molecules li ...