Dot Plot - APBioNET
... Homology is inferred from Similarity If two sequences are similar, then they are known as homologous sequences. Usually, at least 30% identity over 400 bp for DNA sequences and over 125 amino acids for proteins. ...
... Homology is inferred from Similarity If two sequences are similar, then they are known as homologous sequences. Usually, at least 30% identity over 400 bp for DNA sequences and over 125 amino acids for proteins. ...
Pharmacol Rev.2006;58(2):194-243
... clinical use (Table 1) (Robertson, 2001; Lakey et al., 2003; Ricordi and Strom, 2004). The major barrier to islet transplantation is the need for lifelong immunosuppression of the recipient. Once this barrier is overcome, the limitation of islet supply will hamper the use of this procedure (Larkin, ...
... clinical use (Table 1) (Robertson, 2001; Lakey et al., 2003; Ricordi and Strom, 2004). The major barrier to islet transplantation is the need for lifelong immunosuppression of the recipient. Once this barrier is overcome, the limitation of islet supply will hamper the use of this procedure (Larkin, ...
NOVEL SPERM-SPECIFIC GLYCOLYTIC ISOZYMES GENERATED
... mouse genomes. Each glycolytic enzyme is encoded by a family of genes, and there is frequent retrotransposition of a single gene in each family. The same orthologous gene is independently retroposed in both species. Results from this study identified an alternative form of Gpi1 transcribed during mo ...
... mouse genomes. Each glycolytic enzyme is encoded by a family of genes, and there is frequent retrotransposition of a single gene in each family. The same orthologous gene is independently retroposed in both species. Results from this study identified an alternative form of Gpi1 transcribed during mo ...
Glutathione Breakthrough: Advancement in
... GSH plays an important role in antioxidant defense, nutrient metabolism and is key in a vast number of cellular processes including gene expression, DNA and protein synthesis, cell proliferation and apoptosis, signal transduction, cytokine production, immune response, and protein glutathionylation. ...
... GSH plays an important role in antioxidant defense, nutrient metabolism and is key in a vast number of cellular processes including gene expression, DNA and protein synthesis, cell proliferation and apoptosis, signal transduction, cytokine production, immune response, and protein glutathionylation. ...
Export To Word
... Assortment This lesson plan includes excellent teacher support in the form of videos that explain how the pipe cleaners should be manipulated to demonstrate the concepts of mitosis, meiosis, and independent assortment. In this lesson, students demonstrate the law of segregation during meiosis, which ...
... Assortment This lesson plan includes excellent teacher support in the form of videos that explain how the pipe cleaners should be manipulated to demonstrate the concepts of mitosis, meiosis, and independent assortment. In this lesson, students demonstrate the law of segregation during meiosis, which ...
Genetic Control of Root Hair Development in
... appears to be required before either RHD3 or RHD4 because the rhd3 and rhd4 mutants produce hairs that are able to elongate (albeit abnormally), whereas the rhd2 hairs remain very short. Furthermore, the rhd2 rhd3 and rhd2 rhd4 double mutants produce hairs identical in phenotype to the rhd2 mutant a ...
... appears to be required before either RHD3 or RHD4 because the rhd3 and rhd4 mutants produce hairs that are able to elongate (albeit abnormally), whereas the rhd2 hairs remain very short. Furthermore, the rhd2 rhd3 and rhd2 rhd4 double mutants produce hairs identical in phenotype to the rhd2 mutant a ...
Comparative transcriptomics reveals key gene expression
... chemostat. This revealed that the human and bovine pathogens show differential expression of genes encoding a range of functions, including cell wall and secreted proteins, transcriptional regulators, PE/PPE proteins, lipid metabolism and toxin–antitoxin pairs. Furthermore, we probed the gene expres ...
... chemostat. This revealed that the human and bovine pathogens show differential expression of genes encoding a range of functions, including cell wall and secreted proteins, transcriptional regulators, PE/PPE proteins, lipid metabolism and toxin–antitoxin pairs. Furthermore, we probed the gene expres ...
Developmental fate and lineage commitment of singled mouse
... and FS blastomeres, from intact embryos of the corresponding stage, were collected concurrently as controls. At the 2- and 4-cell stages, we analyzed 1/2 and 1/4FS and LS blastomeres, and found that Oct4 expression is comparable between 1/2FS and LS, and 1/4FS and LS, whereas expression of Cdx2 in t ...
... and FS blastomeres, from intact embryos of the corresponding stage, were collected concurrently as controls. At the 2- and 4-cell stages, we analyzed 1/2 and 1/4FS and LS blastomeres, and found that Oct4 expression is comparable between 1/2FS and LS, and 1/4FS and LS, whereas expression of Cdx2 in t ...
Using Drosophila to Understand the Genetics of Circadian Rhythms
... of logical limits, despite their proven utility. In using a mutant adult to study behavior, one must avoid making the unwarranted assumption that any interesting phenotype is due to the absence of the gene product at the time of the assay, without regard to developmental roles for the gene product. ...
... of logical limits, despite their proven utility. In using a mutant adult to study behavior, one must avoid making the unwarranted assumption that any interesting phenotype is due to the absence of the gene product at the time of the assay, without regard to developmental roles for the gene product. ...
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... and FS blastomeres, from intact embryos of the corresponding stage, were collected concurrently as controls. At the 2- and 4-cell stages, we analyzed 1/2 and 1/4FS and LS blastomeres, and found that Oct4 expression is comparable between 1/2FS and LS, and 1/4FS and LS, whereas expression of Cdx2 in t ...
... and FS blastomeres, from intact embryos of the corresponding stage, were collected concurrently as controls. At the 2- and 4-cell stages, we analyzed 1/2 and 1/4FS and LS blastomeres, and found that Oct4 expression is comparable between 1/2FS and LS, and 1/4FS and LS, whereas expression of Cdx2 in t ...
The daily rhythm of mice
... of genetically modified adeno-associated viruses [19]. Tissue-specific knock out mice of the Bmal1 gene in the liver had no functional oscillator in this tissue [20]. In addition, the glucose metabolism in the liver was disturbed. Consequently, these mice exhibited time-restricted hypoglycemia on the ...
... of genetically modified adeno-associated viruses [19]. Tissue-specific knock out mice of the Bmal1 gene in the liver had no functional oscillator in this tissue [20]. In addition, the glucose metabolism in the liver was disturbed. Consequently, these mice exhibited time-restricted hypoglycemia on the ...
Novel p53 mutants selected in BRCA
... transfection assay of p53-dependent growth arrest in Saos-2 (p537/7) cells. Of the 13 mutants tested, only four (163N, 168Y, 234C and 248W) were completely negative for growth arrest whereas the remaining nine mutants exhibited reproducible growth suppressor activity (Figure 2). Mutants with wild-ty ...
... transfection assay of p53-dependent growth arrest in Saos-2 (p537/7) cells. Of the 13 mutants tested, only four (163N, 168Y, 234C and 248W) were completely negative for growth arrest whereas the remaining nine mutants exhibited reproducible growth suppressor activity (Figure 2). Mutants with wild-ty ...
Homeotic genes regulate the spatial expression
... been found to autoregulate, including one, Ubx, that activates its own expression in the visceral mesoderm (Bienz and Tremml, 1988). There must, however, be other genes that are controlled by homeotic genes but are more directly linked to the processes of cell differentiation and morphogenesis. In a ...
... been found to autoregulate, including one, Ubx, that activates its own expression in the visceral mesoderm (Bienz and Tremml, 1988). There must, however, be other genes that are controlled by homeotic genes but are more directly linked to the processes of cell differentiation and morphogenesis. In a ...
of Lactobacillus pentosus
... demonstrated in 8. subtilis, B. licheniformis, and S. xylosus by gel mobility experiments and DNA-footprinting studies (Gârtner et al., 1992, Scheler and Hillen, 1994, Sizemore et al., 1992). The 8. subtilis xyl operator sequence consists of two XyIR binding sites, °L and O, which are spaced by 4 bp ...
... demonstrated in 8. subtilis, B. licheniformis, and S. xylosus by gel mobility experiments and DNA-footprinting studies (Gârtner et al., 1992, Scheler and Hillen, 1994, Sizemore et al., 1992). The 8. subtilis xyl operator sequence consists of two XyIR binding sites, °L and O, which are spaced by 4 bp ...
MyGene.info Documentation
... “refseq” and “accession” fields now contain accession number including version. Data can be search with and without version. Version is available for “genomic”, “rna” and “protein” accession number keys. Note: “genomic” field is returned but is not searchable v2: http://mygene.info/v2/query?q=NM_052 ...
... “refseq” and “accession” fields now contain accession number including version. Data can be search with and without version. Version is available for “genomic”, “rna” and “protein” accession number keys. Note: “genomic” field is returned but is not searchable v2: http://mygene.info/v2/query?q=NM_052 ...
UB_GO_Apr_2004 - Buffalo Ontology Site
... 1372 component terms 7271 function terms 8069 process terms http:// ifomis.de ...
... 1372 component terms 7271 function terms 8069 process terms http:// ifomis.de ...
CURRICULUM VITAE Name: Antonella Spinazzola Nationality
... The study showed that MNGIE results from a deficiency of thymidine phosphorylase, an enzyme that catalyzes the reversible breakdown of thymidine to thymine plus deoxyribose-1-phosphate. The report underlies the importance of understanding the nature and sources of mitochondrial DNA precursor pools s ...
... The study showed that MNGIE results from a deficiency of thymidine phosphorylase, an enzyme that catalyzes the reversible breakdown of thymidine to thymine plus deoxyribose-1-phosphate. The report underlies the importance of understanding the nature and sources of mitochondrial DNA precursor pools s ...
SOLUTIONS TO NEET 2017 - (7-5-2017) - Code P
... Thalassemia and sickle cell anemia are caused due to a problem in globin molecules synthesis. Select the CORRECT statement. (1) Both are due to a qualitative defect in globin chain synthesis. (2) Both are due to a quantitative defect in globin chain synthesis. (3) Thalassemia is due to less synthesi ...
... Thalassemia and sickle cell anemia are caused due to a problem in globin molecules synthesis. Select the CORRECT statement. (1) Both are due to a qualitative defect in globin chain synthesis. (2) Both are due to a quantitative defect in globin chain synthesis. (3) Thalassemia is due to less synthesi ...
Finding New Clock Components: Past and Future
... Drosophilia double-time, and hamster tau mutants fall into this category in which mutations caused ≥4-h period changes and null mutations were not available. One could of course argue that this analysis is biased—we have only gone after the extreme mutations, and so these are the ones that we know a ...
... Drosophilia double-time, and hamster tau mutants fall into this category in which mutations caused ≥4-h period changes and null mutations were not available. One could of course argue that this analysis is biased—we have only gone after the extreme mutations, and so these are the ones that we know a ...
pyrimidine
... Uses short primer that attaches to the 3’ end of the ssDNA, after which a specially engineered DNA polymerase Each vial includes one dideoxyXTP and 3 ordinary dXTPs; the dideoxyXTP will be incorporated but will halt synthesis because the 3’ position is blocked. See figs. 11.3 & 11.4 for how these ar ...
... Uses short primer that attaches to the 3’ end of the ssDNA, after which a specially engineered DNA polymerase Each vial includes one dideoxyXTP and 3 ordinary dXTPs; the dideoxyXTP will be incorporated but will halt synthesis because the 3’ position is blocked. See figs. 11.3 & 11.4 for how these ar ...
the lkb1 tumor suppressor - E
... The first oncogenes (e.g. src, Ha-ras) were originally discovered in the DNA of retrovirus genomes having the capacity to induce malignant transformation of cultured cells. Subsequently, the same oncogenes were found also in human cancer cells (Bishop, 1981) (Parada et al., 1982). Surprisingly, even ...
... The first oncogenes (e.g. src, Ha-ras) were originally discovered in the DNA of retrovirus genomes having the capacity to induce malignant transformation of cultured cells. Subsequently, the same oncogenes were found also in human cancer cells (Bishop, 1981) (Parada et al., 1982). Surprisingly, even ...
Dysfunction of Wild-Type Huntingtin in Huntington
... expressed wild-type huntingtin may include a protective mechanism from various apoptotic stimuli. Huntingtin also affects neuronal stability because its deletion in mice causes degeneration of axon fibers (3). Various evidence has converged to indicate that wild-type huntingtin may be involved in ce ...
... expressed wild-type huntingtin may include a protective mechanism from various apoptotic stimuli. Huntingtin also affects neuronal stability because its deletion in mice causes degeneration of axon fibers (3). Various evidence has converged to indicate that wild-type huntingtin may be involved in ce ...
Chapter 4 - DORAS
... grown in LB broth and the appropriate antibiotics, was used to inoculate 5 ml aliquots of M63 minimal media (section 2.2). These M63 cultures were then incubated at 37oC overnight and used to seed the M63 bioassays. To prepare the bioassays, M63 agar (25 ml) supplemented with 100 μM of the iron chel ...
... grown in LB broth and the appropriate antibiotics, was used to inoculate 5 ml aliquots of M63 minimal media (section 2.2). These M63 cultures were then incubated at 37oC overnight and used to seed the M63 bioassays. To prepare the bioassays, M63 agar (25 ml) supplemented with 100 μM of the iron chel ...
Math of Genetics - College of William & Mary
... How Genes Are Inherited The average human had 46 chromosomes (2 sets of ...
... How Genes Are Inherited The average human had 46 chromosomes (2 sets of ...
A conserved N-‐terminal domain of Rif2 regulates telomere length in
... Telomere sequence DNA repeats are bound by a set of proteins that mediate two essential functions; first to protect the ends from degradation, recombination, and initiation of a damage response, and second ...
... Telomere sequence DNA repeats are bound by a set of proteins that mediate two essential functions; first to protect the ends from degradation, recombination, and initiation of a damage response, and second ...