Stochastic Gene Expression:
... fixed. A simple and possibly common way to do this is if [P] activates a process that makes further fluctuation in [P] irrelevant. P could, for instance, be a transcription factor that activates another gene with a more stable activation kinetics. Such a mechanism would require that the response to ...
... fixed. A simple and possibly common way to do this is if [P] activates a process that makes further fluctuation in [P] irrelevant. P could, for instance, be a transcription factor that activates another gene with a more stable activation kinetics. Such a mechanism would require that the response to ...
The transformation suppressor protein Pdcd4 shuttles
... eucaryotic translation initiation factors (eIFs) eIF4A and eIF4G (Göke et al., 2002; Kang et al., 2002; Yang et al., 2003), suggesting that it might be involved in regulating protein translation. In support of this idea, Yang et al. (2003) have localized the protein to the cytoplasm and have demons ...
... eucaryotic translation initiation factors (eIFs) eIF4A and eIF4G (Göke et al., 2002; Kang et al., 2002; Yang et al., 2003), suggesting that it might be involved in regulating protein translation. In support of this idea, Yang et al. (2003) have localized the protein to the cytoplasm and have demons ...
Red blood cells
... No easily overt detectable signs of sickle pain So children known to have sickle cell disorder who say they are in pain must be trusted If they can rely on the adults around them to take them seriously, they are less likely to take advantage of their condition to seek attention or avoid distaste ...
... No easily overt detectable signs of sickle pain So children known to have sickle cell disorder who say they are in pain must be trusted If they can rely on the adults around them to take them seriously, they are less likely to take advantage of their condition to seek attention or avoid distaste ...
Chapter 4 The role of mutation in evolution
... many higher organisms are on the order of one mistake per billion nucleotides copied. As fantastically low as this error rate seems, it might seem that mutations could not be terribly important. But an organism that was able to copy its DNA perfectly every time would find its supply of variation wou ...
... many higher organisms are on the order of one mistake per billion nucleotides copied. As fantastically low as this error rate seems, it might seem that mutations could not be terribly important. But an organism that was able to copy its DNA perfectly every time would find its supply of variation wou ...
Construction and Characterization of a Highly Regulable Expression
... Minimal M9 and rich LB media used in this study were prepared as described by Miller (1972). The antibiotics ampicillin, kanamycin, streptomycin, and tetracycline were used in rich media at final concentrations of 100, 40, 200, and 20 g/ml, respectively. When used in minimal media, tetracycline was ...
... Minimal M9 and rich LB media used in this study were prepared as described by Miller (1972). The antibiotics ampicillin, kanamycin, streptomycin, and tetracycline were used in rich media at final concentrations of 100, 40, 200, and 20 g/ml, respectively. When used in minimal media, tetracycline was ...
ABG505
... Polledness In general, the presence or absence of horns can be attributed to the action of two alleles at an autosomal locus with the polled (P) being dominant to the horned (p). Many breeds of domestic livestock are horned and are therefore homozygous for p. ...
... Polledness In general, the presence or absence of horns can be attributed to the action of two alleles at an autosomal locus with the polled (P) being dominant to the horned (p). Many breeds of domestic livestock are horned and are therefore homozygous for p. ...
![[ 19] Saccharomyces Genome Database - SGD-Wiki](http://s1.studyres.com/store/data/012906934_1-a4c322e0bc64d409034f1882ecf44124-300x300.png)
[ 19] Saccharomyces Genome Database - SGD-Wiki
... This chapter describes the organization of SGD, the sources of the data stored in SGD, some methods for retrieving information from the database, connections SGD has with outside databases and non-yeast research communities, and SGD's repository of yeast community information. This is not a complete ...
... This chapter describes the organization of SGD, the sources of the data stored in SGD, some methods for retrieving information from the database, connections SGD has with outside databases and non-yeast research communities, and SGD's repository of yeast community information. This is not a complete ...
Slide 1
... recognises the SNP at site 4257G>A. In both gels, Lanes 1 and 6 represent 100 bp DNA ladder as molecular marker. Lane 2 represent undigested PCR products. Lane 3 represents RFLP patterns seen when only the respective wild-type alleles are present. Lane 4 shows RFLP patterns when only the respective ...
... recognises the SNP at site 4257G>A. In both gels, Lanes 1 and 6 represent 100 bp DNA ladder as molecular marker. Lane 2 represent undigested PCR products. Lane 3 represents RFLP patterns seen when only the respective wild-type alleles are present. Lane 4 shows RFLP patterns when only the respective ...
J Biol Chem, v 275, pp 12237-12242
... T-type family, or Cav3, encoded by ␣1G (Cav3.1), ␣1H, and ␣1I (2). The  subunit family is less diverse, with only four genes cloned so far (3). Co-expression studies have established two physiological roles of  subunits in high voltage-activated Ca2⫹ channels: they dramatically increase ␣1 express ...
... T-type family, or Cav3, encoded by ␣1G (Cav3.1), ␣1H, and ␣1I (2). The  subunit family is less diverse, with only four genes cloned so far (3). Co-expression studies have established two physiological roles of  subunits in high voltage-activated Ca2⫹ channels: they dramatically increase ␣1 express ...
Saccharomyces Genome Database.
... This chapter describes the organization of SGD, the sources of the data stored in SGD, some methods for retrieving information from the database, connections SGD has with outside databases and non-yeast research communities, and SGD's repository of yeast community information. This is not a complete ...
... This chapter describes the organization of SGD, the sources of the data stored in SGD, some methods for retrieving information from the database, connections SGD has with outside databases and non-yeast research communities, and SGD's repository of yeast community information. This is not a complete ...
Supplementary Information (doc 63K)
... biallelic ATM (ATM mutation + 11q deletion) defects were included. In addition, TP53-mutant CLL samples were to a large extent derived from patients with chemorefractory disease. In total, the training cohort consisted of 14 TP53/ATM wild type (WT), 9 TP53- and 7 ATM-defective samples (Supplemental ...
... biallelic ATM (ATM mutation + 11q deletion) defects were included. In addition, TP53-mutant CLL samples were to a large extent derived from patients with chemorefractory disease. In total, the training cohort consisted of 14 TP53/ATM wild type (WT), 9 TP53- and 7 ATM-defective samples (Supplemental ...
Alpha -antitrypsin alleles in patients with ... emphysema, detected by DNA amplification ...
... with determination of the AAT concentration in serum, been the method of choice for AAT phenotyping. The technique is rather simple but interpretation of the bands can be difficult and demands skilled personnel. The method can identify about 60 protein variants including the deficient AAT types, PiZ ...
... with determination of the AAT concentration in serum, been the method of choice for AAT phenotyping. The technique is rather simple but interpretation of the bands can be difficult and demands skilled personnel. The method can identify about 60 protein variants including the deficient AAT types, PiZ ...
From DNA to Protein Structure and Function - Science Take-Out
... shape. It is this specific shape that allows each protein to perform a specific job. The combination of specific proteins that your body makes gives you your traits. ...
... shape. It is this specific shape that allows each protein to perform a specific job. The combination of specific proteins that your body makes gives you your traits. ...
mutations that affect an entire chromosomes Chromosomal
... • A point mutation may not change the amino acid that is coded for • Even if a change occurs, the change may be in an intron that is removed & this has no effect • A change may not significantly affect the function of a protein if the new amino acid is similar to the correct one or occurs away from ...
... • A point mutation may not change the amino acid that is coded for • Even if a change occurs, the change may be in an intron that is removed & this has no effect • A change may not significantly affect the function of a protein if the new amino acid is similar to the correct one or occurs away from ...
Gene as the unit of genetic material - E
... of two copies of ribosomal DNA sequence mostly found as inverted repeats. The symbiotic origin of the chloroplast: Due to certain characteristics the chloroplast is comparable to a symbiotic organism living inside the plant cell. They divide, grow and differentiate. They contain circular DNA, ...
... of two copies of ribosomal DNA sequence mostly found as inverted repeats. The symbiotic origin of the chloroplast: Due to certain characteristics the chloroplast is comparable to a symbiotic organism living inside the plant cell. They divide, grow and differentiate. They contain circular DNA, ...
Expression of Wnt-1 in PC12 Cells Results in Modulation of
... level of Armadillo protein is found in a broad stripe of cells including those which express wingless (60, 63). This localized increase in Armadillo protein is dependent on wingless function and so appears to be a specific cellular response to the wingless signal (58, 60, 63). Armadillo protein is c ...
... level of Armadillo protein is found in a broad stripe of cells including those which express wingless (60, 63). This localized increase in Armadillo protein is dependent on wingless function and so appears to be a specific cellular response to the wingless signal (58, 60, 63). Armadillo protein is c ...
4. Inducers of apoptosis
... The mass cells we loseduring each year close to our entire brain body weight! brain for nine months, finally contriving the one model that could be human, equipped for language. ...
... The mass cells we loseduring each year close to our entire brain body weight! brain for nine months, finally contriving the one model that could be human, equipped for language. ...
GUEST COMMENTARY
... From what I had just been taught at the university the possibility of isolating such fusions was an obvious corollary of what was known of operons. For me, the operon was a fact. For Francois Jacob, it was still a theory.” Part of the reason for this less than enthusiastic endorsement of genetic fus ...
... From what I had just been taught at the university the possibility of isolating such fusions was an obvious corollary of what was known of operons. For me, the operon was a fact. For Francois Jacob, it was still a theory.” Part of the reason for this less than enthusiastic endorsement of genetic fus ...
BWS - Beckwith-Wiedemann Syndrome support
... or in women. Sometimes gene expression must be restricted to different parts of the body e.g. the genes responsible for sight must only be expressed in your eyes. Gene activity is controlled by chemical switches. As we have discussed, you inherit two copies of each gene: one copy from your mother ( ...
... or in women. Sometimes gene expression must be restricted to different parts of the body e.g. the genes responsible for sight must only be expressed in your eyes. Gene activity is controlled by chemical switches. As we have discussed, you inherit two copies of each gene: one copy from your mother ( ...
a recent publication illustrating this here
... easy to see for asynchronous populations of cycling cells in which all biochemical states are extant at any given time. Analysis of the ‘‘regulatory’’ cell cycle within this context is more easily digested when layered on a backbone of phases and stages that we ‘‘understand’’ from kinetics and morph ...
... easy to see for asynchronous populations of cycling cells in which all biochemical states are extant at any given time. Analysis of the ‘‘regulatory’’ cell cycle within this context is more easily digested when layered on a backbone of phases and stages that we ‘‘understand’’ from kinetics and morph ...
Overview of molecular methods in immunohematology
... to the IgG removal treatment; and 4) diagnostic antibodies require the indirect antiglobulin test and IgG removal techniques are not effective at removing bound immunoglobulin. DNA-based assays are also useful as a tool to distinguish alloantibodies from autoantibodies and to identify the molecular ...
... to the IgG removal treatment; and 4) diagnostic antibodies require the indirect antiglobulin test and IgG removal techniques are not effective at removing bound immunoglobulin. DNA-based assays are also useful as a tool to distinguish alloantibodies from autoantibodies and to identify the molecular ...
Biol 415 Quiz #1 Study Outline Mechanisms of Evolution
... -What influences spatial patterns of genetic variation? slides 8-9 -What is reticulate evolution? Does it occur? slide 10 -What’s the difference between population genetics, phylogenetics and phylogeography? slides 11-12 -What are the pros and cons of using mitochondrial, chloroplast or nuclear ...
... -What influences spatial patterns of genetic variation? slides 8-9 -What is reticulate evolution? Does it occur? slide 10 -What’s the difference between population genetics, phylogenetics and phylogeography? slides 11-12 -What are the pros and cons of using mitochondrial, chloroplast or nuclear ...
The Cyclin-Dependent Kinase Inhibitor KRP2
... correlation was found between the amount of transgenic KRP2 protein and the level of CDK inhibition. This observation points toward the presence of a KRP2-resistant fraction of CDK/cyclin complexes that cannot be inhibited by KRP2, even at high levels. As reported previously, strong KRP2OE lines had ...
... correlation was found between the amount of transgenic KRP2 protein and the level of CDK inhibition. This observation points toward the presence of a KRP2-resistant fraction of CDK/cyclin complexes that cannot be inhibited by KRP2, even at high levels. As reported previously, strong KRP2OE lines had ...