Biophysics 101 Genomics and Computational Biology
... Sugar-binding and crystallographic studies of an arabinose-binding protein mutant (Met108Leu) that exhibits enhanced affinity & altered T7 RNA polymerase mutants with altered promoter specificities. The specificity of carboxypeptidase Y may be altered by changing the hydrophobicity of the S'1 bindin ...
... Sugar-binding and crystallographic studies of an arabinose-binding protein mutant (Met108Leu) that exhibits enhanced affinity & altered T7 RNA polymerase mutants with altered promoter specificities. The specificity of carboxypeptidase Y may be altered by changing the hydrophobicity of the S'1 bindin ...
A global picture of tRNA genes in plant genomes
... are found in animals but are absent in fungi or higher plants. However, Sec-containing proteins were found in the green algae C. reinhardtii (Novoselov et al., 2002). As incorporation of selenocysteine into proteins requires a specific tRNA designated tRNASec, such a tRNA is present in C. reinhardti ...
... are found in animals but are absent in fungi or higher plants. However, Sec-containing proteins were found in the green algae C. reinhardtii (Novoselov et al., 2002). As incorporation of selenocysteine into proteins requires a specific tRNA designated tRNASec, such a tRNA is present in C. reinhardti ...
gmod-update-07nov - IUBio Archive for Biology
... http://eugenes.org/gmod/docs/gmod-intro-07oct.pdf ...
... http://eugenes.org/gmod/docs/gmod-intro-07oct.pdf ...
Bioinformatics Sequencing
... – Phylogenetic trees can be constructed based on comparison of the sequences of a molecule (example: 16S rRNA) taken from different species – Residues conserved during evolution play an important role ...
... – Phylogenetic trees can be constructed based on comparison of the sequences of a molecule (example: 16S rRNA) taken from different species – Residues conserved during evolution play an important role ...
Document
... Finding SNPs: HapMap Browser 1. HapMap data sets are useful because individual genotype data in deeply sampled populations can be used to determine optimal genotyping strategies (tagSNPs) or perform population genetic analyses (linkage disequilbrium) ...
... Finding SNPs: HapMap Browser 1. HapMap data sets are useful because individual genotype data in deeply sampled populations can be used to determine optimal genotyping strategies (tagSNPs) or perform population genetic analyses (linkage disequilbrium) ...
Pedigree vs. Genomic Inbreeding
... • Adjusting for base level of homozygosity in population • 10% homozygosity ...
... • Adjusting for base level of homozygosity in population • 10% homozygosity ...
Import of genetically modified carnation `Moonaqua`
... genes and theoretically give rise to the formation of new open reading frames (ORFs) consisting of host and donor sequences. Therefore, applicants are required to analyse the border and bordering sequences of the insertion for the presence of chimer ORFs. The applicant characterised the T-DNA coding ...
... genes and theoretically give rise to the formation of new open reading frames (ORFs) consisting of host and donor sequences. Therefore, applicants are required to analyse the border and bordering sequences of the insertion for the presence of chimer ORFs. The applicant characterised the T-DNA coding ...
Document
... Every cell in the human body contains the entire human genome: 3.3 Gb or ~30K genes. The investigation of gene expression is meaningful because different cells, in different environments, doing different jobs express different genes. Tasks necessary for gene expression analysis: Define what a gene i ...
... Every cell in the human body contains the entire human genome: 3.3 Gb or ~30K genes. The investigation of gene expression is meaningful because different cells, in different environments, doing different jobs express different genes. Tasks necessary for gene expression analysis: Define what a gene i ...
Requirements for Human Medical Genome
... (Refer to Standard 1 and Standard 2 in Requirements for Medical Pathology Services) Medical testing by genomic methods shares many ethical, legal and social issues with other forms of clinical investigation. Existing issues of informed consent, incidental findings, the right not to know, family stud ...
... (Refer to Standard 1 and Standard 2 in Requirements for Medical Pathology Services) Medical testing by genomic methods shares many ethical, legal and social issues with other forms of clinical investigation. Existing issues of informed consent, incidental findings, the right not to know, family stud ...
Expression of phosphofructokinase in Neisseria meningitidis
... thus function in both glycolysis and gluconeogenesis. PPiPFK (EC 2.7.1.90) has a more limited distribution, but is also found in eukaryotes and bacteria (Bapteste et al., 2003). ATP-PFK and PPi-PFK share a common ancestry, but phylogenies show a very complex evolutionary pattern (Muller et al., 2001 ...
... thus function in both glycolysis and gluconeogenesis. PPiPFK (EC 2.7.1.90) has a more limited distribution, but is also found in eukaryotes and bacteria (Bapteste et al., 2003). ATP-PFK and PPi-PFK share a common ancestry, but phylogenies show a very complex evolutionary pattern (Muller et al., 2001 ...
Microarrays
... detection reaction (LDR). This approach utilizes the discriminatory power of ligase that joins ends of two discriminatory probes, thus allowing single nucleotide differentiation. LDR probe pairs targeting 15 groups of bacterial pathogens frequently contaminating dairy products were developed and val ...
... detection reaction (LDR). This approach utilizes the discriminatory power of ligase that joins ends of two discriminatory probes, thus allowing single nucleotide differentiation. LDR probe pairs targeting 15 groups of bacterial pathogens frequently contaminating dairy products were developed and val ...
Nutritional Genomics
... Our findings provide evidence that maternal diet during mid-to-late gestation can modulate gene expression in fetal tissues in sheep Gene set enrichment analysis revealed many functional categories, including terms related to ...
... Our findings provide evidence that maternal diet during mid-to-late gestation can modulate gene expression in fetal tissues in sheep Gene set enrichment analysis revealed many functional categories, including terms related to ...
Divergent Evolutionary and Expression Patterns between Lineage
... chainPreNet, chainNet and netSyntenic to pick up the best and longest chain. We also used faSize to calculate the size of chromosomes or scaffolds involved the alignment. (5) We used faToTwoBit to switch the ‘fasta’ format of the chromosome or scaffold sequences into ‘2bit’ format. We transformed th ...
... chainPreNet, chainNet and netSyntenic to pick up the best and longest chain. We also used faSize to calculate the size of chromosomes or scaffolds involved the alignment. (5) We used faToTwoBit to switch the ‘fasta’ format of the chromosome or scaffold sequences into ‘2bit’ format. We transformed th ...
MycoplasMa Quality control
... These adverse effects can lead to the misinterpretation of results and compromise the validity of data generated for research and/or development projects. Importance of routine testing Because mycoplasma can affect the phenotypic and functional characteristics of cells in vitro, the implementation o ...
... These adverse effects can lead to the misinterpretation of results and compromise the validity of data generated for research and/or development projects. Importance of routine testing Because mycoplasma can affect the phenotypic and functional characteristics of cells in vitro, the implementation o ...
the Gene Ontology
... are over-represented or under-represented. Grouping gene products by biological function. Relating a protein’s location to its function. Focusing on particular biological pathways and functions (hypothesis-driven data interrogation). ...
... are over-represented or under-represented. Grouping gene products by biological function. Relating a protein’s location to its function. Focusing on particular biological pathways and functions (hypothesis-driven data interrogation). ...
RIBOSWITCHES - Creighton Chemistry Webserver
... the expression of metabolic genes metabolic product of a pathway inhibits expression of proteins required to produce the metabolite ...
... the expression of metabolic genes metabolic product of a pathway inhibits expression of proteins required to produce the metabolite ...
Article The Pseudoautosomal Regions of the U/V Sex
... due to their being genetically linked to the nonrecombining, sex-determining region. This phenomenon is expected to occur in both diploid (XY, ZW) and haploid (UV) sexual systems, with slightly different consequences for UV sexual systems because of the absence of masking during the haploid phase (w ...
... due to their being genetically linked to the nonrecombining, sex-determining region. This phenomenon is expected to occur in both diploid (XY, ZW) and haploid (UV) sexual systems, with slightly different consequences for UV sexual systems because of the absence of masking during the haploid phase (w ...
Transvection and pairing of a Drosophila Hox long noncoding RNA
... with translocations or inversions with breakpoints mapping to the fushi tarazu– Antennapedia (ftz-Antp) interval result in mis-regulation of Scr in trans, on the wildtype (wt) chromosome (Southworth and Kennison 2002). Interestingly, these GOF mutations break within a region in the ftz-Antp interval ...
... with translocations or inversions with breakpoints mapping to the fushi tarazu– Antennapedia (ftz-Antp) interval result in mis-regulation of Scr in trans, on the wildtype (wt) chromosome (Southworth and Kennison 2002). Interestingly, these GOF mutations break within a region in the ftz-Antp interval ...
A novel arginine substitution mutation in 1A domain and a novel 27
... region have been reported.26–29 The proband of family B carries a novel duplication insertion of 27 nucleotides (1222ins27). This type of mutation is unique for a number of different reasons. Firstly, in-frame insertion or deletion mutations are extremely rare in keratin diseases (table 2), and this ...
... region have been reported.26–29 The proband of family B carries a novel duplication insertion of 27 nucleotides (1222ins27). This type of mutation is unique for a number of different reasons. Firstly, in-frame insertion or deletion mutations are extremely rare in keratin diseases (table 2), and this ...
Genetic recombination in plants
... available for many plant species, for example Arabidopsis, maize, rice, tomato, soybean, wheat, and barley. In some cases, most notably Arabidopsis [l&15], tomato [16-191 and rice [ZO], these YAC and BAC clones are being organized into large contigs. These concigs represent a resource for investigat ...
... available for many plant species, for example Arabidopsis, maize, rice, tomato, soybean, wheat, and barley. In some cases, most notably Arabidopsis [l&15], tomato [16-191 and rice [ZO], these YAC and BAC clones are being organized into large contigs. These concigs represent a resource for investigat ...