Point mutations in BCL6 DNA-binding domain reveal distinct
... We show here by point mutation analysis that the six ZFs of BCL6 are not equivalent in DNA-binding activity. Similar findings were reported for the POK proteins ZF5 and Kaiso [12 and 13]. The described experiments differed from our work though, as the ZF region of these two proteins was not examined ...
... We show here by point mutation analysis that the six ZFs of BCL6 are not equivalent in DNA-binding activity. Similar findings were reported for the POK proteins ZF5 and Kaiso [12 and 13]. The described experiments differed from our work though, as the ZF region of these two proteins was not examined ...
- Wiley Online Library
... Enzymes: DXS, 1-deoxy-D-xylulose-5-phosphate synthase; DXR, 1-deoxy-D-xylulose-5-phosphate reductoisomerase; CMS, 4-diphosphocytidyl-2-C-methylD-erythritol synthase; CMK, 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; MCS, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; HDS, 1hydroxy-2-me ...
... Enzymes: DXS, 1-deoxy-D-xylulose-5-phosphate synthase; DXR, 1-deoxy-D-xylulose-5-phosphate reductoisomerase; CMS, 4-diphosphocytidyl-2-C-methylD-erythritol synthase; CMK, 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; MCS, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; HDS, 1hydroxy-2-me ...
Assaying … promoter activity
... In order to determine whether the transposome had really inserted at random into the genome, we examined the sequences in the genome into which the transposons had inserted. To do this, we first recovered each of the transposons along with a portion of the adjacent genomic DNA via a plasmid rescue p ...
... In order to determine whether the transposome had really inserted at random into the genome, we examined the sequences in the genome into which the transposons had inserted. To do this, we first recovered each of the transposons along with a portion of the adjacent genomic DNA via a plasmid rescue p ...
Spider Silk - Consortium for Mathematics and its Applications
... resistance to tearing, and toughness. Spider silk would be an ideal material for a large variety of medical and technical applications, and researchers are thus interested in learning the spiders’ secrets and imitating their technique.[1] This unit has a direct purpose and an indirect purpose. Its d ...
... resistance to tearing, and toughness. Spider silk would be an ideal material for a large variety of medical and technical applications, and researchers are thus interested in learning the spiders’ secrets and imitating their technique.[1] This unit has a direct purpose and an indirect purpose. Its d ...
Bacteroides mobilizable and conjugative genetic elements
... Stevens et al.13 have presented evidence suggesting that the control of production of these circular DNA forms resides in a region contained within the Tcr transfer element called ERL (confers Tcr and MLS resistance). Halula and Macrina14 have also reported the partial cloning of Tcr, MLSr element, ...
... Stevens et al.13 have presented evidence suggesting that the control of production of these circular DNA forms resides in a region contained within the Tcr transfer element called ERL (confers Tcr and MLS resistance). Halula and Macrina14 have also reported the partial cloning of Tcr, MLSr element, ...
Slide 1
... Effects of Mutations How do mutations affect genes? The effects of mutations on genes vary widely. Some have little or no effect; and some produce beneficial variations. Some negatively disrupt gene function. Mutations often produce proteins with new or altered functions that can be useful to organi ...
... Effects of Mutations How do mutations affect genes? The effects of mutations on genes vary widely. Some have little or no effect; and some produce beneficial variations. Some negatively disrupt gene function. Mutations often produce proteins with new or altered functions that can be useful to organi ...
Engineering of steroid biotransformation in rhodococcus van
... Four structural genes, i.e. kshA, kshB, kstD and kstD2, have been identified in R. erythropolis strain SQ1, encoding the enzymes involved in AD degradation. The genomic loci of these genes appear to be scattered over the genome of R. erythropolis SQ1. No operon (-like) organization was apparent and ...
... Four structural genes, i.e. kshA, kshB, kstD and kstD2, have been identified in R. erythropolis strain SQ1, encoding the enzymes involved in AD degradation. The genomic loci of these genes appear to be scattered over the genome of R. erythropolis SQ1. No operon (-like) organization was apparent and ...
Evolutionary History of Free-Swimming and
... several authors, including Darwin (1871) and, more recently, Tokioka (1971), Jollie (1973), and Jefferies (1986). In contrast, Garstang (1928) proposed that the ancestral chordates had sessile adults and that the tadpole-like body plan evolved in the larval stage of these ancestors. Cephalochordates ...
... several authors, including Darwin (1871) and, more recently, Tokioka (1971), Jollie (1973), and Jefferies (1986). In contrast, Garstang (1928) proposed that the ancestral chordates had sessile adults and that the tadpole-like body plan evolved in the larval stage of these ancestors. Cephalochordates ...
Complete Thyroxine-Binding Globulin (TBG) Deficiency Produced
... To evaluate the effect of this mutation on the splicing pattern, it was necessary to determine the sequence of TBG mRNA. TBG mRNA is transcribed in liver and therefore is not readily accessible for sampling. We attempted illegitimate amplification of TBG mRNA from peripheral blood leukocytes, as pre ...
... To evaluate the effect of this mutation on the splicing pattern, it was necessary to determine the sequence of TBG mRNA. TBG mRNA is transcribed in liver and therefore is not readily accessible for sampling. We attempted illegitimate amplification of TBG mRNA from peripheral blood leukocytes, as pre ...
comparing quantitative trait loci and gene expression data
... QTL and microarray data is not completely straightforward. First, the estimated range of QTL positions is generally wide, containing thousands of putative genes. However, QTL analysis may also miss some interesting genes (Wayne and Mclntyre, 2002). Second, the high level of experimental error and li ...
... QTL and microarray data is not completely straightforward. First, the estimated range of QTL positions is generally wide, containing thousands of putative genes. However, QTL analysis may also miss some interesting genes (Wayne and Mclntyre, 2002). Second, the high level of experimental error and li ...
Nucleotide
... (2) RNA Transcription—a process of converting or “transcribing” the deoxyribonucleotide sequence within one strand of DNA into single-stranded RNAs such as the messenger RNA (or mRNA) (3) RNA Translation—a process whereby the genetic information carried by mRNA is “translated” into the synthesis of ...
... (2) RNA Transcription—a process of converting or “transcribing” the deoxyribonucleotide sequence within one strand of DNA into single-stranded RNAs such as the messenger RNA (or mRNA) (3) RNA Translation—a process whereby the genetic information carried by mRNA is “translated” into the synthesis of ...
Evolution of Metabolisms - Theoretical and Computational
... Ferredoxins, besides thioredoxin, avodoxin, and rubredoxin, are important coenzymes in metabolic pathways. They serve as electron acceptors and donors in many anabolic, catabolic, and electron transfer reactions. For example, ferredoxin is a redox partner in more than 50 known pathways. An example ...
... Ferredoxins, besides thioredoxin, avodoxin, and rubredoxin, are important coenzymes in metabolic pathways. They serve as electron acceptors and donors in many anabolic, catabolic, and electron transfer reactions. For example, ferredoxin is a redox partner in more than 50 known pathways. An example ...
CBSE XII BIO QS with key(2009-2015)
... Why do moss plants produce very large number of male gametes? Provide one reason. What are these gametes called?(2015) To compensate the loss of male gametes during their transport ( to the non-motile female gametes) through water/ to increase chances of fertilization, antherozoids=1+1 A liverwort p ...
... Why do moss plants produce very large number of male gametes? Provide one reason. What are these gametes called?(2015) To compensate the loss of male gametes during their transport ( to the non-motile female gametes) through water/ to increase chances of fertilization, antherozoids=1+1 A liverwort p ...
Genetics of Down Syndrome
... with an improvement of the investigation methods. The direct preparation of meristematic somatic cells was followed by long-term and shortterm cell cultures of differentiated somatic cells removed postpartum, by the culture of amniotic fluid specimen and biopsy of chorionic villi, as well as the ana ...
... with an improvement of the investigation methods. The direct preparation of meristematic somatic cells was followed by long-term and shortterm cell cultures of differentiated somatic cells removed postpartum, by the culture of amniotic fluid specimen and biopsy of chorionic villi, as well as the ana ...
Rearrangements in the Human T-Cell-Receptor Â
... Particularly close association of HTLV-I infection with leukemogenesis of ATL has often been reported by a number of serological and epidemiológica! studies (1,2). However, lack of oncogenes in the HTLV-I genome (3) and the occurrence of disease in a very small proportion (0.01-0.02%) of HTLV-Iinfe ...
... Particularly close association of HTLV-I infection with leukemogenesis of ATL has often been reported by a number of serological and epidemiológica! studies (1,2). However, lack of oncogenes in the HTLV-I genome (3) and the occurrence of disease in a very small proportion (0.01-0.02%) of HTLV-Iinfe ...
Dot Plot - APBioNET
... Homology: When two similar proteins come from a common ancestor. Homology is inferred from Similarity If two sequences are similar, then they are known as homologous sequences. Usually, at least 30% identity over 400 bp for DNA sequences and over 125 amino acids for proteins. ...
... Homology: When two similar proteins come from a common ancestor. Homology is inferred from Similarity If two sequences are similar, then they are known as homologous sequences. Usually, at least 30% identity over 400 bp for DNA sequences and over 125 amino acids for proteins. ...
Simplified Insertion of Transgenes Onto Balancer Chromosomes via
... ABSTRACT Balancer chromosomes are critical tools for Drosophila genetics. Many useful transgenes are inserted onto balancers using a random and inefficient process. Here we describe balancer chromosomes that can be directly targeted with transgenes of interest via recombinase-mediated cassette exchan ...
... ABSTRACT Balancer chromosomes are critical tools for Drosophila genetics. Many useful transgenes are inserted onto balancers using a random and inefficient process. Here we describe balancer chromosomes that can be directly targeted with transgenes of interest via recombinase-mediated cassette exchan ...
A Novel Multigene Family May Encode Odorant Receptors: A
... cDNAs defines a new multigene family that shares sequence and structural properties with the seven transmembrane domain superfamily of neurotransmitter and hormone receptors. This novel family, however, exhibits features different from any other member of the receptor superfamily thus far identified ...
... cDNAs defines a new multigene family that shares sequence and structural properties with the seven transmembrane domain superfamily of neurotransmitter and hormone receptors. This novel family, however, exhibits features different from any other member of the receptor superfamily thus far identified ...
Genomic overview of serine proteases
... ends of each of these clusters did not reveal any sequence similarity to serine proteases. We also mapped the four serine proteases that form a cluster on chromosome 14q11.2–q11.3 and found that all genes are transcribed from telomere to centromere. Genes of this cluster are generally smaller (2.7–3 ...
... ends of each of these clusters did not reveal any sequence similarity to serine proteases. We also mapped the four serine proteases that form a cluster on chromosome 14q11.2–q11.3 and found that all genes are transcribed from telomere to centromere. Genes of this cluster are generally smaller (2.7–3 ...
Conspiracy of silence among repeated transgenes
... genomes have mechanisms for recognizing potentially threatening sequence elements, like transposons, and silencing them. Cytosine methylation is believed to serve this purpose in most eukaryotic taxa.(26) RIGS seems to be another genome defense mechanism, one that operates both in organisms that hav ...
... genomes have mechanisms for recognizing potentially threatening sequence elements, like transposons, and silencing them. Cytosine methylation is believed to serve this purpose in most eukaryotic taxa.(26) RIGS seems to be another genome defense mechanism, one that operates both in organisms that hav ...
