Alterations to the remote control of Shh gene expression cause
... Figure 1. Complex long-range regulators control Shh expression during development. The mouse Shh gene is depicted (not to scale) showing the coding region and the relative location of the known Shh enhancers (blue ovals). Brain (SBE1 – 4) and floorplate enhancers (SFPE1,2) reside inside the gene and ...
... Figure 1. Complex long-range regulators control Shh expression during development. The mouse Shh gene is depicted (not to scale) showing the coding region and the relative location of the known Shh enhancers (blue ovals). Brain (SBE1 – 4) and floorplate enhancers (SFPE1,2) reside inside the gene and ...
Presence of multiple group I introns closely 23S rRNAs of lichen-forming
... More importantly, all of these putative proteins contained one LAGLIDADG motif, identified by using Pfam v21.10 [17], characteristic of the HE involved in intron mobility. The LAGLIDADG family of HE comprises more than 200 proteins and is the most diverse of the HE families since its members are pre ...
... More importantly, all of these putative proteins contained one LAGLIDADG motif, identified by using Pfam v21.10 [17], characteristic of the HE involved in intron mobility. The LAGLIDADG family of HE comprises more than 200 proteins and is the most diverse of the HE families since its members are pre ...
DNA Evolution 3.1 Troubleshooting and Debugging Guide
... Each of the processes described below writes logs which are described in each section below. Look for CRITICAL messages in the log files to determine the key issues. PLEASE NOTE: Keep in mind that enabling the trace level to 5 should not be left on machines with automated jobs for a long period of t ...
... Each of the processes described below writes logs which are described in each section below. Look for CRITICAL messages in the log files to determine the key issues. PLEASE NOTE: Keep in mind that enabling the trace level to 5 should not be left on machines with automated jobs for a long period of t ...
Genomic Insights into Methanotrophy: The Complete Genome Sequence of Methylococcus capsulatus (Bath)
... genomes, many of these elements share higher intra- than intergenome similarity. This suggests several possible mechanisms: expansion of these elements since their introduction into the M. capsulatus (Bath) genome, repeated cycles of duplication and subsequent deletion, or gene conversion. Twenty el ...
... genomes, many of these elements share higher intra- than intergenome similarity. This suggests several possible mechanisms: expansion of these elements since their introduction into the M. capsulatus (Bath) genome, repeated cycles of duplication and subsequent deletion, or gene conversion. Twenty el ...
Skeletal muscle actin mRNA. Characterization of the 3
... was made by comparing their nucleotide sequences (Fig. 2). The insert of plasmid plO6 was completely sequenced (Fig. 2). The insert starts with a nucleotide t r i p l e t coding for phenylalanine (actin C-terminal residue), followed by a translation termination codon (TAG). I t contains 240 nucleoti ...
... was made by comparing their nucleotide sequences (Fig. 2). The insert of plasmid plO6 was completely sequenced (Fig. 2). The insert starts with a nucleotide t r i p l e t coding for phenylalanine (actin C-terminal residue), followed by a translation termination codon (TAG). I t contains 240 nucleoti ...
Interdependence, Reflexivity, Fidelity, Impedance Matching
... It is important, therefore, to assess the experimental data on which the hypothesis rests and to separate data that genuinely support the hypothesis from those that only appear to do so. Selecting ever more proficient RNA aptamers from large combinatorial libraries based originally on selfsplicin ...
... It is important, therefore, to assess the experimental data on which the hypothesis rests and to separate data that genuinely support the hypothesis from those that only appear to do so. Selecting ever more proficient RNA aptamers from large combinatorial libraries based originally on selfsplicin ...
Pourcel et al., Microbiology 2005
... same at all three sites, except for the very first repeat, which lacks a few base-pairs. (b) On one side of the CRISPR structure, a conserved region of less than 200 bp called the leader sequence is observed. The leader sequences from the three sites are aligned; asterisks indicate identity in all t ...
... same at all three sites, except for the very first repeat, which lacks a few base-pairs. (b) On one side of the CRISPR structure, a conserved region of less than 200 bp called the leader sequence is observed. The leader sequences from the three sites are aligned; asterisks indicate identity in all t ...
USMLE Step 1 - Becker Professional Education
... of State Medical Boards (FSMB) and National Board of Medical Examiners® (NBME®). United States Medical Licensing Examination, USMLE, National Board of Medical Examiners, and NBME are registered trademarks of the National Board of Medical Examiners. The National Board of Medical Examiners does not sp ...
... of State Medical Boards (FSMB) and National Board of Medical Examiners® (NBME®). United States Medical Licensing Examination, USMLE, National Board of Medical Examiners, and NBME are registered trademarks of the National Board of Medical Examiners. The National Board of Medical Examiners does not sp ...
Interdependence, Reflexivity, Fidelity, Impedance Matching
... It is important, therefore, to assess the experimental data on which the hypothesis rests and to separate data that genuinely support the hypothesis from those that only appear to do so. Selecting ever more proficient RNA aptamers from large combinatorial libraries based originally on selfsplicin ...
... It is important, therefore, to assess the experimental data on which the hypothesis rests and to separate data that genuinely support the hypothesis from those that only appear to do so. Selecting ever more proficient RNA aptamers from large combinatorial libraries based originally on selfsplicin ...
Report - TrSys - Jacobs University
... dimensions (2-D). The 2-D plots of ECM show that most mutations occur between codons that encode the same amino acid, i.e., the changes from one codon to another will not change the amino acid to be produced. Furthermore, most of the highly probable inter-amino acid mutations will not result in a dr ...
... dimensions (2-D). The 2-D plots of ECM show that most mutations occur between codons that encode the same amino acid, i.e., the changes from one codon to another will not change the amino acid to be produced. Furthermore, most of the highly probable inter-amino acid mutations will not result in a dr ...
wsp Gene Sequences from the Wolbachia of Filarial Nematodes
... coded by multicopy genes [13, 14]. For example, Ehrlichia chaffensis has at least six copies (tandemly arranged with intergenic spacers) of the gene coding for the major outer membrane proteins [13]. The proteins coded by these genes show up to approximately 20% amino acid difference. Trees based on ...
... coded by multicopy genes [13, 14]. For example, Ehrlichia chaffensis has at least six copies (tandemly arranged with intergenic spacers) of the gene coding for the major outer membrane proteins [13]. The proteins coded by these genes show up to approximately 20% amino acid difference. Trees based on ...
Prediction and investigation of novel proteins in DNA double
... broken ends to close proximity and Dnl4/Lif1/Nej1 ligates the DNA ends. Protein-protein interaction (PPI) has been utilized in functional genomics studies to identify novel proteins involved in different pathways based on their PPI profiles. In this study we aim to screen for novel proteins involved ...
... broken ends to close proximity and Dnl4/Lif1/Nej1 ligates the DNA ends. Protein-protein interaction (PPI) has been utilized in functional genomics studies to identify novel proteins involved in different pathways based on their PPI profiles. In this study we aim to screen for novel proteins involved ...
Transposable elements in Escherichia coli antimicrobial resistance
... Since they have the intrinsic ability to multiply during the transposition process, they are automatically amplified, with a large copy number, restricted only by the carrying capacity of their environment (i.e. the genome) [1]. Transposons often persist in genomes over millions of years. This requi ...
... Since they have the intrinsic ability to multiply during the transposition process, they are automatically amplified, with a large copy number, restricted only by the carrying capacity of their environment (i.e. the genome) [1]. Transposons often persist in genomes over millions of years. This requi ...
... could still have some free binding sites for biotin, thus becoming more-sensitive detection reagents in pertinent applications. (d) Biotin is a small molecule (244.31 Da) that, when introduced into biologically active macromolecules, in most cases does not affect their biological activity, e.g., enz ...
Cloning and functional expression of invertebrate connexins from
... it should be noted that the reported sequence identity between these two families is very low [7]. Innexins display only 16% overall identity when their full-length amino acid sequences are compared to either connexins or pannexins, which may simply reflect that all three gene families encode four t ...
... it should be noted that the reported sequence identity between these two families is very low [7]. Innexins display only 16% overall identity when their full-length amino acid sequences are compared to either connexins or pannexins, which may simply reflect that all three gene families encode four t ...
Bio CET 2015 Key Answers
... Solution : Variable number of tandem repeats are the loci for DNA fingerprinting techniques, Introns and Exons are spliced to form a processed eukaryotic mRNA, Dystrophin is the largest gene measuring up to 2.4 Mb the Satellite DNA contains repeats that bulk the DNA content. Smack and Crack are prod ...
... Solution : Variable number of tandem repeats are the loci for DNA fingerprinting techniques, Introns and Exons are spliced to form a processed eukaryotic mRNA, Dystrophin is the largest gene measuring up to 2.4 Mb the Satellite DNA contains repeats that bulk the DNA content. Smack and Crack are prod ...
RNA Interference and Small Interfering RNAs
... Natural sources for aberrant RNAs or dsRNAs may be repetitive and mobile genetic elements such as transposons, or natural viruses. Integration of such elements nearby the promoters of endogenous genes is hypothesized to lead to unexpected antisense transcripts that at least partially anneal to the s ...
... Natural sources for aberrant RNAs or dsRNAs may be repetitive and mobile genetic elements such as transposons, or natural viruses. Integration of such elements nearby the promoters of endogenous genes is hypothesized to lead to unexpected antisense transcripts that at least partially anneal to the s ...
supporting information
... PLP epitope clusters: We selected the epitope clusters for PLP to reside within amino acids 38-52, 103-150, 177-203, 218-240 and 264-276: The PLP38-52 contains epitopes preferentially recognized by DR2 and D4 MS T-cells [13], one of the H-2d strains, BALB/cPt, is also moderately susceptible to EAE ...
... PLP epitope clusters: We selected the epitope clusters for PLP to reside within amino acids 38-52, 103-150, 177-203, 218-240 and 264-276: The PLP38-52 contains epitopes preferentially recognized by DR2 and D4 MS T-cells [13], one of the H-2d strains, BALB/cPt, is also moderately susceptible to EAE ...
Sequence and phylogenetic analysis of the gp200 protein of
... five known species-specific epitopes. The gp200 amino acid sequences of the Taiwanese genotype bore 94.4∼94.6 identities with those of the isolates from the United States and Brazil, and 93.7% homology with that of the Israeli isolate. Taken together, these results suggest that the Taiwanese genotyp ...
... five known species-specific epitopes. The gp200 amino acid sequences of the Taiwanese genotype bore 94.4∼94.6 identities with those of the isolates from the United States and Brazil, and 93.7% homology with that of the Israeli isolate. Taken together, these results suggest that the Taiwanese genotyp ...
A number of antibiotics produced by different - J
... which has been shown to be an inhibitor of yeast RNA polymerases in vitro6,7) and it has been suggested that prokaryotic RNA synthesis is also sensitive to this antibiotic8,9). However, we found that the RNA polymerases of the five organisms used in this study were unaffected by thiolutin in vitro ( ...
... which has been shown to be an inhibitor of yeast RNA polymerases in vitro6,7) and it has been suggested that prokaryotic RNA synthesis is also sensitive to this antibiotic8,9). However, we found that the RNA polymerases of the five organisms used in this study were unaffected by thiolutin in vitro ( ...