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... processes responsible for the replication and expression of genetic information. Furthermore, the ability to isolate a specific segment of DNA, modify it in a test tube, and transfer it back into the same or a different cell to create a genetically modified organism represents perhaps the most signi ...
Fifteen years of genomewide scans for selection: trends, lessons
Fifteen years of genomewide scans for selection: trends, lessons

... profound about evolution, as this would suggest a subset of the genome’s diversity is the primary source of evolutionary change at both micro- and macroscales. Indeed, previous authors have found some interspecific evidence that supports disproportionate targeting of certain DNA regions. For example ...
Chapt. 14 Eukaryotic mRNA processing I: splicing 14.1 Genes are in
Chapt. 14 Eukaryotic mRNA processing I: splicing 14.1 Genes are in

... • Most ‘higher eukaryotic’ genes coding for mRNA and tRNA (some rRNA) are interrupted by introns • Exons surround introns: contain sequences that finally appear in the mature RNA product – Genes for mRNAs have 0 to 362 exons (titin) – tRNA genes have either 0 or 1 exon Introns present in genes, not ...
Bioethics Thesaurus for Genetics
Bioethics Thesaurus for Genetics

... SN The study of or belief in the possibility of improving the qualities of the human species or a human population, esp. by such means as discouraging reproduction by persons having genetic defects or presumed to have inheritable undesirable traits (negative eugenics) or encouraging reproduction by ...
What is Sequence Alignment?
What is Sequence Alignment?

Mitochondrial Transcript Processing and Restoration of Male Fertility
Mitochondrial Transcript Processing and Restoration of Male Fertility

... hybrid seed in a number of crops. The Texas or T-cytoplasmic male-sterile (cms-T) system was used extensively in the 1960s to eliminate the need for hand detasseling in hybrid maize production. As a consequence of the 1970 epidemic of southern corn leaf blight, cms-T is no longer widely used commerc ...
Methylation of the Factor IX Gene is the Main Source of Mutations
Methylation of the Factor IX Gene is the Main Source of Mutations

Fig 16.12a - McGraw Hill Higher Education
Fig 16.12a - McGraw Hill Higher Education

... Each gene can have many regulatory proteins • In humans, ~2000 genes encode transcriptional regulatory proteins • Each regulatory protein can act on many genes ...
Representation and High-Quality Annotation of
Representation and High-Quality Annotation of

... DOI 10.1055/s-2005-837578 ´ Published online April 15, 2005 ISSN 1435-8603 ...
CH Zinc Fingers As DNA Binding Domains
CH Zinc Fingers As DNA Binding Domains

... Louis. *The number is f o r proteins containing two C2C2 fingers. finger proteins can be divided into four classes (Fig. 2), (A) single C2H2, (B) triple C2H2, (C) multiple-adjacent C2H2, and (D) separated-paired C2H2 zinc finger proteins. ^^ This classification is usefiil to predict how the zinc fin ...
MicroRNAs: key participants in gene regulatory networks
MicroRNAs: key participants in gene regulatory networks

... Mutations in genes required for miRNA biosynthesis lead to genetic developmental defects; these dramatic consequences are derived, at least in part, from the role of generating miRNAs [22]. Although the details are still obscure, the outline of the miRNA biosynthesis pathway is beginning to emerge. ...
Obligate phototrophy in cyanobacteria: more than a lack of sugar
Obligate phototrophy in cyanobacteria: more than a lack of sugar

... distinct characteristics. In P. boryanum uptake is inducible by glucose, and the glucose analogue Kmethyl-glucoside shows high competitive e¡ect rather than OMG in Synechocystis [6^8]. The transport system has no a¤nity for fructose, which is transported via a distinct system and also used as a subs ...
Mutations of APC, K-ras, and p53 Are Associated
Mutations of APC, K-ras, and p53 Are Associated

... been superseded by the advent of new molecular cytogenetic techniques, in particular, CGH (9). Studies of colorectal cancer using CGH have shown the frequent occurrence of chromosomal aberrations such as gain of 20q, 13q, 7p, and 8q and loss of 18q, 17p, and 8p (10 –14). Moreover, some chromosomal a ...
DNA Three Way Junction Core Decorated with Amino Acids
DNA Three Way Junction Core Decorated with Amino Acids

... a catalytic site made of these appended functionalities since DNA folding into various secondary structures can be easily predicted following the Watson-Crick rules. With the aim to use in vitro selection methods, the Hollenstein0 s group developed triphosphate deoxynucleosides bearing the amino aci ...
Two Genes with Similarity to Bacterial Response Regulators Are
Two Genes with Similarity to Bacterial Response Regulators Are

... amino acid sequence contains a 10-kD C-terminal extension that has a Ser/Pro–rich stretch (32 Ser/Pro of 52 total residues) followed by a short acidic domain (Figure 1B). This domain of IBC7 does not share high primary sequence homology to any other sequences in GenBank and is not present in IBC6. I ...
FLUORESCENT PROTEIN IN Escherichia coli
FLUORESCENT PROTEIN IN Escherichia coli

Regulation of the S100B gene by α1-adrenergic - AJP
Regulation of the S100B gene by α1-adrenergic - AJP

... 3,5,3⬘-triiodothyronine (T3), as described in MATERIALS AND METHODS. The results of a representative experiment are presented. GAPDH mRNA was used as an internal control for the RT-PCR reaction. The sizes of the RT-PCR products for rat S100B (500 bp), human S100B (210 bp), and GAPDH (720 bp) are ind ...
ELEM_CouvC_V1n3 copy
ELEM_CouvC_V1n3 copy

... corner-linked SiO4 tetrahedra bound to layers of edgelinked AlO6 octahedra (FIG. 1). These sheets bind to each other like “a deck of cards” by van der Waals forces and interlayer cations. The idealized chemical formula for montmorillonite clay is Al4Si8O20(OH)4, though the actual formula varies as a ...
Tendency for Local Repetitiveness in Amino Acid Usages in Modern
Tendency for Local Repetitiveness in Amino Acid Usages in Modern

... Systematic analyses of human proteins show that neural and immune system-speci®c, and therefore, relatively ``modern'' proteins have a tendency for repetitive use of amino acids at a local scale (1-20 residues), while ancient proteins (human homologues of Escherichia coli proteins) do not. Those pr ...
Article 1 Title: The pseudoautosomal regions of the U/V sex
Article 1 Title: The pseudoautosomal regions of the U/V sex

... recombining region is usually not lost completely and it is thought that most species retain a PAR because homologous recombination in this region plays a critical role in chromosomal pairing and segregation during meiosis [4,5]. Moreover, there are situations where sexually antagonistic forces may ...
Sequencing
Sequencing

Regulation of Bacterial Conjugation in Microaerobiosis by
Regulation of Bacterial Conjugation in Microaerobiosis by

... host-encoded regulators may control conjugal transfer in most (perhaps all) F-like plasmids while others may be plasmid specific. For instance, F transfer undergoes a drastic decrease in stationary phase (Frost and Manchak 1998), a behavior that is not observed in pSLT (Camacho et al. 2005b). Anothe ...
statistical issues in the analysis of microbial communities in soil
statistical issues in the analysis of microbial communities in soil

... the natural amplification of this molecule within the organism due to the large number of ribosomes in each cell, and the availability of the Ribosomal Database Project (RDPII) (Maidak et al., 2001), which contains over 16,000 different 168 rRNA sequences for comparison. Likewise, the regions of the ...
DNA Evidence: Probability, Population Genetics, and the Courts
DNA Evidence: Probability, Population Genetics, and the Courts

3D Plus transfection reagent
3D Plus transfection reagent

... serum-free medium during the first 12h of incubation. 2) The presence of antibiotics might affect cell health and transfection efficiency. 10- Incubation time and transfection volume. The optimal time range between transfection and assay varies with cells, promoter, expression product, etc. The tran ...
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Non-coding DNA

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