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Transvection and pairing of a Drosophila Hox long noncoding RNA
Transvection and pairing of a Drosophila Hox long noncoding RNA

... with translocations or inversions with breakpoints mapping to the fushi tarazu– Antennapedia (ftz-Antp) interval result in mis-regulation of Scr in trans, on the wildtype (wt) chromosome (Southworth and Kennison 2002). Interestingly, these GOF mutations break within a region in the ftz-Antp interval ...
Transgenic approaches for optogenetics Tim Murphy UBC.
Transgenic approaches for optogenetics Tim Murphy UBC.

Aberrant DNA methylation in cancer: potential clinical
Aberrant DNA methylation in cancer: potential clinical

... affect the genetic code. The human genome exhibits a clear depletion of CpG dinucleotides, presumably due to the high rate of deamination of 5-methylcytosine to thymine (Ref. 1). However, the genome also contains small stretches, up to a few kilobases in length, that are comparatively rich in CpG di ...
Organization of chromosomes in the interphase cell - UvA-DARE
Organization of chromosomes in the interphase cell - UvA-DARE

... of Belmont observed chromatin fibers with diameters of on average 100 nm, so-called chromonema. In Gl nuclei, chromonema have predominantly a diameter of 100-130 nm, which decreases during progression in the cell cycle to predominantly 60-80 nm in early S-phase (Belmont and Bruce, 1994). The authors ...
Te gades
Te gades

... Why  Te#gades?   •  *Not  all  Te#gades  species  studied  has  this   double  lineage  of  Hodgkina   •  To  look  at  this  phenomena  phylogene0cally,   we  decided  to  sequence  the  cicadas  harboring   these  bacteria   •  Thus  we ...
Protein_synthesis__my_version_
Protein_synthesis__my_version_

... dictated by the next mRNA codon. It sits in the A site (site for new tRNA entrants). Enzymes in the large subunit of the ribosome cause the new amino acid to join to the already existing polypeptide (which was in the P site). The new tRNA that brought in the new amino acid now holds the entire polyp ...
VECTOR SYSTEMS XXVII.indd
VECTOR SYSTEMS XXVII.indd

Functional Genomics
Functional Genomics

... Several of the articles in this Insight discuss new technologies that are being developed to understand function on a genome-wide scale. Are these approaches conceptually different from what biologists have been doing for many years, or is it just the scale on which experiments can be done that is d ...
Evolution of the Actin Gene Family in Testate Lobose Amoebae
Evolution of the Actin Gene Family in Testate Lobose Amoebae

... We estimate that the actin gene family contains 40–50 paralogous members in each lineage. None of the three independent lineages share the same paralog with another, and divergence between actins reaches 29% in contrast to just 2% in SSU-rDNA. Analyses of effective number of codons (ENC), compositio ...
Bacterial genome replication at subzero temperatures in permafrost
Bacterial genome replication at subzero temperatures in permafrost

... representing B25% of the global soil organic matter. Although much of the observed subzero microbial activity may be due to basal metabolism or macromolecular repair, there is also ample evidence for cellular growth. Unfortunately, most metabolic measurements or culture-based laboratory experiments ...
The maize ID1 flowering time regulator is a zinc finger protein with
The maize ID1 flowering time regulator is a zinc finger protein with

... As a prelude to the identi®cation of target genes regulated by ID1 we present here a detailed study of the target binding site speci®city and the DNA binding activity of ID1. Using in vitro analysis techniques we show that the ID domain recognizes and speci®cally interacts with a contiguous 11 bp se ...
PPT - UCLA Health
PPT - UCLA Health

... of the expression of thousands of genes and may enable researchers to identify genetic changes rapidly and efficiently. Tissue from up to 1,000 histology blocks can be arrayed onto a newly created paraffin block at designated locations. Molecular markers can then be applied, with information assesse ...


... For measuring the similarity between sequences two approaches generally are used; global alignment and local alignment. In global similarity algorithms, the entire lengths of sequences are subject for representing the best alignment. This method will produce an alignment with large stretches of low ...
Phylogeny of elasmobranchs based on LSU and SSU ribosomal
Phylogeny of elasmobranchs based on LSU and SSU ribosomal

... weaknesses: Parametric bootstrapping is more statistically rigorous but it is heavily reliant on the accuracy of the evolutionary model it uses to simulate sequence data and thus is prone to Type 1 statistical errors, but the SH test makes so many simplifying assumptions that it is highly prone to T ...
chromosome disorders.
chromosome disorders.

... • It has been apparent for nearly 50 years that chromosome abnormalities—microscopically visible changes in the number or structure of chromosomes—could account for a number of clinical conditions that are thus referred to as chromosome ...
Microbiology
Microbiology

... Identification of DNA homologous to GRH2-14 and GRH2-50 mutant loci in Rhizobium Genomic DNA from various Rbixobiztm species was examined for homology to the mutant loci of GRH2-14 and GRH2-50 by Southern blot hybridization. DNA fragments homologous to the GRH2-50 DNA probe (Fig. la) were found in R ...
Surface polysaccharide mutants of Rhizobium sp. (Acacia) strain
Surface polysaccharide mutants of Rhizobium sp. (Acacia) strain

The Rat Gene Map
The Rat Gene Map

... conserved autosomal chromosome segments is only 33. Of the 20 singletons, 8 appear to be located inside existing segments. The maximal number of conserved segments indicated by the present data set is 61—about half the number of segments found when either species is compared with human. It should be ...
Synapsis-Mediated Fusion of Free DNA Ends Forms Inverted Dimer Plasmids in Yeast.
Synapsis-Mediated Fusion of Free DNA Ends Forms Inverted Dimer Plasmids in Yeast.

... The formation of inverteddimer plasmids may berelatedto some forms ofchromosomal rearrangement. These might include the fusion of broken sister chromatids in the bridge-breakagefusion cycle and the head-to-head duplication of genomic DNA at the sites of gene amplifications. ...
werribee secondary college vce unit planner ~ 2004
werribee secondary college vce unit planner ~ 2004

... nature and production of vaccines and antibody serums and their importance in maintaining immunity for a particular disease in the human population Thursday: contd. Friday: SAC 5: A poster in response to a stimulus on an issue related to immune system Homework: unit 3 past paper Monday: binary fissi ...
1 Single molecule sequencing of THCA synthase reveals
1 Single molecule sequencing of THCA synthase reveals

... of  inactive  THCAS  stochastically  amplifying  given  the  PCR  reactions  were  set  up   independently.  Gradient  PCR  at  lower  annealing  temperatures  with  the  Onofri  primers   may  unveil  additional  diverged  pseudogenes.  A  f ...
DNA cytosine methylation in plant development
DNA cytosine methylation in plant development

... (Bird, 2002). A striking difference in the cytosine methylation patterns in plants from those in animals is that although methylation is predominantly occurring at the CG dinucleotides in plants, it is not confined to these sites; instead, methylation also occurs at CHG (where H is A, C or T) and as ...
Test Info Sheet
Test Info Sheet

... The clinical sensitivity of sequencing and deletion/duplication analysis of the genes included in this panel depends in part on the patient’s clinical phenotype. Specific information about the diagnostic yield for each gene in selected populations is summarized in the following table. The technical ...
2q13 microdeletions
2q13 microdeletions

... other genes, environment and unique personality help to determine their future development, needs and achievements. It is very important to see your child as an individual and not to rely on direct comparisons with others who appear to have the same or a similar loss of DNA. ...
Chromosomal rearrangements and protein globularity changes in
Chromosomal rearrangements and protein globularity changes in

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Non-coding DNA

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