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Structure-Function Analysis of the Conserved Histone Chaperone
Structure-Function Analysis of the Conserved Histone Chaperone

... Chromatin  structure  is  crucial  to  regulate  access  to  the  genome  for  processes  such   as  transcription,  recombination,  DNA  repair,  and  DNA  replication.    Spt6,  a  key  factor   involved  in  regulating  chromatin  struct ...
Detection of genetically modified plants
Detection of genetically modified plants

... prepared outside the organism including micro-injection, macro-injection and microencapsulation; 3) Cell fusion (including protoplast fusion) or hybridisation techniques where live cells with new combinations of heritable genetic material are formed through the fusion of two or more cells by means o ...
Conformational Changes in HIV-1 Reverse Transcriptase Induced
Conformational Changes in HIV-1 Reverse Transcriptase Induced

... chains of Y181 and Y188, and the displacement of the β12β13-β14 sheet (discussed above). The long-range distortions involve a hinge-bending movement of the p66 thumb subdomain that results in the displacements of the p66 connection, the RNase H domain, and the p51 subunit relative to the polymerase ...
Preferential X-chromosome inactivation, DNA
Preferential X-chromosome inactivation, DNA

... interspecific crosses - mules and hybrids between foxes do not show preferential X-inactivation (Serov et al. I978a,b). In these latter examples of strain- and species-specific X chromosome imprinting, non-random X chromosome expression is not concerned with whether the X chromosome comes from the m ...
ORF distribution and statistics
ORF distribution and statistics

... Error  rates  of  NGS  sequencing  range  from  0.1%  to  0.6%,  depending   on  the  platform   and  the  depth  of  coverage. Wall  J D  et  al  (2014)  Estimating  genotype  error  rates  f rom  high-­coverage  next-­generation  s equence  data,  Genome   Res  24:1734-­9.   ...
Ribosomal frameshifting in decoding antizyme mRNAs from yeast
Ribosomal frameshifting in decoding antizyme mRNAs from yeast

... years. As pointed out previously we have been unable to amplify it from human genomic DNA (14). Based on these and other considerations, we now believe that this cDNA is a contaminant, most likely a mammalian antizyme 1 gene belonging to an unidentified rabbit or hare species. In our search for new a ...
thymine dimers - Glen Research
thymine dimers - Glen Research

... It has been clear to us for some time that of skin cancer. Polymerases encountering unrepaired researchers into DNA damage and repair would value CPD lesions are quite error-prone, presumably the ability to produce oligonucleotides containing leading to incorrect base insertions and subsequent cis-s ...
Sequence comparison of aflR from different Aspergillus species
Sequence comparison of aflR from different Aspergillus species

... Cys6 Zn2 DNA-binding domain and C-terminal transcription activation domain typical of GAL4-type fungal and yeast transcription factors. AflR binds to the partially palindromic consensus sequence 50 -TCGN5 CGR-30 found in promoters of most of the aflatoxin biosynthesis genes (Chang et al., 1995; Ehrlic ...
Lecture-Mic 623-Plasmids-Listeria - Home
Lecture-Mic 623-Plasmids-Listeria - Home

... often deadly disease. The CDC reports approximately 2,500 cases a year, 500 of which are fatal. This is more than Salmonella and Botulism. ...
Prokaryotic orthologues of mitochondrial alternative oxidase and plastid terminal oxidase
Prokaryotic orthologues of mitochondrial alternative oxidase and plastid terminal oxidase

... The alignment showed that all six putative ironbinding residues (E-183, E-222, H-225, E-273, E-324, H-327) are conserved in all PTOX and AOX proteins (Figure 2). Besides these, the following amino acids were also completely conserved: L-182, A-186, H198, N-221, A-276, Y-280, and D-323 (numbering acc ...
Compaction of Duplex Nucleic Acids upon Native
Compaction of Duplex Nucleic Acids upon Native

Genome-wide analysis by SNP Array
Genome-wide analysis by SNP Array

... CGH Array provides a pangenomic analysis of the human genome with a better resolution than that used in karyotyping analysis4,5. Currently, CGH Array is based on the competitive hybridisation of the DNA of the patient being tested (labelled by a green fluorochrome) and a normal DNA reference (labell ...
Taxonomic characterization of Ochrobactrum sp. isolates from soil
Taxonomic characterization of Ochrobactrum sp. isolates from soil

... scales of taxonomic resolution and for an evaluation of exogenous influences on microbial diversity in soil. It is, however, an essential prerequisite for such studies to unambiguously identify and characterize the investigated strains at and below the species level. The objective of the present stu ...
Introduction to Genetics
Introduction to Genetics

...  X-inactivation (also called lyonization) is a process by which one of the two copies of the X chromosome present in female mammals is inactivated  X-inactivation occurs so that the female, with two X chromosomes, does not have twice as many X chromosome gene products as the male, which only posse ...
A standard nomenclature for von Willebrand factor gene mutations
A standard nomenclature for von Willebrand factor gene mutations

De novo mutations in familial adenomatous polyposis (FAP)
De novo mutations in familial adenomatous polyposis (FAP)

... like Apert syndrome12 and multiple endocrine neoplasia type 2B.10 Paternal bias is frequently observed but the parental origin of different genetic disorders is complex and the present results resembles those found in von Hippel-Lindau disease.14 The failure to observe an underlying paternal bias am ...
Drosophila Muller F Elements Maintain a Distinct Set of Genomic
Drosophila Muller F Elements Maintain a Distinct Set of Genomic

... analyses only focused on the Muller elements A–E and the properties of the F element generally have not been examined carefully. In this study, we have built on these genomic resources by performing manual sequence improvement and gene annotation of the D. erecta, D. mojavensis, and D. grimshawi F e ...
DNA
DNA

... More Terminology • The genome is an organism’s complete set of DNA. ...
Primer on Molecular Biology
Primer on Molecular Biology

... More Terminology • The genome is an organism’s complete set of DNA. ...
Primer on Molecular Biology
Primer on Molecular Biology

... More Terminology • The genome is an organism’s complete set of DNA. ...
UCSD_PevznerMolecula.. - Purdue University :: Computer Science
UCSD_PevznerMolecula.. - Purdue University :: Computer Science

... More Terminology • The genome is an organism’s complete set of DNA. ...
operon
operon

... • Although attenuation was once considered to be an unusual type of regulation, it is relatively common • This is especially true for operons involved in amino acid biosynthesis • In some operons, attenuation complements regulation via the operator; in others it is the only means of regulation © 201 ...
Mechanisms of Transcription-Replication
Mechanisms of Transcription-Replication

... are virtually identical to those for the P7 promoter (compare Fig. 4B to Fig. 3D). Since very different promoters cause similar inhibitory effects on replication, it is likely that the act of transcription, rather than the nature of a promoter, is responsible for this effect. When the trc promoter w ...
Establishment of new mutations under divergence and genome
Establishment of new mutations under divergence and genome

... speciation, where gene flow constantly introduces the wrong combination of genes into a local population [17,22–24]. These considerations apply when speciation is initiated in the face of gene flow, as well as when some divergence initially occurs in allopatry and then a period of secondary contact ...
Report Organelles in Blastocystis that Blur the
Report Organelles in Blastocystis that Blur the

... same organelles is more suggestive of hydrogenosomal metabolism. To clarify the metabolic properties of the Blastocystis MLOs, we used 3330 clusters constructed from our EST data for a comparative BLAST search against the yeast and human mitochondrial proteomes [14, 15]. In addition, the KEGG Automa ...
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Non-coding DNA

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