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History of DNA - Duplin County Schools
History of DNA - Duplin County Schools

... to the discovery of the DNA molecule structure. This discovery was made by American biologist, ...
Molecular_genetics_revision_checklist
Molecular_genetics_revision_checklist

... In eukaryotes - control of metabolic pathways by gene expression includes enhancers and transcription factors. Students should understand the role of control elements, including the promoter region, enhancer region, the transcription factors (proteins) that must bind to both regions before transcrip ...
2.5.15 Summary - Intermediate School Biology
2.5.15 Summary - Intermediate School Biology

... 1. Chop the onions into small pieces. 2. Add the chopped onion to the beaker with the salt and washing up liquid solution and stir. 3. Put the beaker in the water bath at 600C for exactly 15 minutes. 4. Cool the mixture by standing the beaker in the ice-water bath for 5 minutes. 5. Pour the mixture ...
Table S1: Description of the cohort used for the novel - HAL
Table S1: Description of the cohort used for the novel - HAL

... Genomic structure of the SHANK genes There are three human SHANK genes and the topology of the SHANK protein phylogenetic tree indicates that the gene duplication giving rise to SHANK2 and SHANK3 occurred after the SHANK1 split (Figure S1). The encoded proteins contain ankyrin domains (ANK), one SH ...
Fulltext PDF - Indian Academy of Sciences
Fulltext PDF - Indian Academy of Sciences

... eutherian mammals this requires a random switch and subsequent maintenance of the active and inactive states. Holliday and Pugh discussed these fundamental features in the wider context of development. Both publications proposed that the hemimethylated DNA after replication is a substrate for a main ...
DNA and its Structure
DNA and its Structure

... hydrogens bonds between the nitrogenous bases  They also said that DNA is shaped like a twisted ladder, or double helix ...
Molecular genetics of bacteria
Molecular genetics of bacteria

... – In repression, the genes normally in use are shut off when no longer needed. ...
Gene Regulation - Biomedical Informatics
Gene Regulation - Biomedical Informatics

... intervening non-coding introns. 47. In prokaryotic cells, translation of an mRNA into protein can begin from the 5’ end of the mRNA even while the 3’ end is still being copied from DNA. 48. In eukaryotic cells, the primary RNA transcript of a protein-coding gene must undergo several modifications, c ...
ACTA2 - Cincinnati Children`s Hospital Medical Center
ACTA2 - Cincinnati Children`s Hospital Medical Center

... All 9 exons of the ACTA2 gene, as well as the exon/intron boundaries and portion of untranslated regions of the gene are amplified by PCR. Genomic DNA sequences from both forward and reverse directions are obtained by automatic fluorescent detection using an ABI PRISM® 3730 DNA Analyzer. Sequence va ...
Molecular Biology Powerpoint
Molecular Biology Powerpoint

... Helicase breaks Hydrogen Bonds between chains Opens the zipper ...
GENERAL ZOOLOGY LECTURE EXAM 2
GENERAL ZOOLOGY LECTURE EXAM 2

... 10. During crossing-over, non-sister chromatids exchange DNA at locations called: a. chiasmata b. synapsis c. centromeres d. kinetochores e. equatorial plate 11. What was the most significant result Gregor Mendel drew from his experiments with pea plants? a. There is considerable genetic variation i ...
(part of a “developmental reprogramming”). The roots of evolutionary
(part of a “developmental reprogramming”). The roots of evolutionary

... Selector genes are genes that regulate (turning on or off) the expression of other genes. Thus selector genes act as "master switches" in development. Wings and all their associated structures are complicated pieces of machinery. Nonetheless, mutations in a single gene, were able to cause the repro ...
3. All of the parts of a cell are controlled by the
3. All of the parts of a cell are controlled by the

...  What happens during transcription?  What happens during translation? ...
Stem cells - Plain Local Schools
Stem cells - Plain Local Schools

... a. When the repressor changes shape it no longer binds to the operator b. The operator is open and RNA polymerase binds to the promoter c. The lactose processing genes are turned on d. When lactose is no longer present – the repressor can rebind to the operator D. Prokaryotes waste little energy on ...
plasmid to transform
plasmid to transform

... Characteristics of a useful plasmid. i. Single recognition site • Plasmid only cuts in one place, so this ensures that the plasmid is reformed in the correct order. ii. Origin of replication • Allows plasmid to replicate and make copies for new cells. iii. Marker genes • Identifies cells that have b ...
Finding Genes
Finding Genes

... small potential coding sequences like this will occur frequently by chance, and therefore the longer they are the more likely they are to represent real coding regions, genes Problems Small genes may be missed The actual start codon may be internal to the ORF There may be overlapping genes ...
Pombe.mating.hm
Pombe.mating.hm

... strand is resected and then the resulting single-stranded DNA invades H1 region of mat2P or mat3M. Lab strains mat2Δ mat3Δ still have dsDNA break, but it is repaired probably by a nonhomologous end-joining (NHEJ), since the donor cassettes are missing. Question: What would happen if homologous recom ...
Biotechnology
Biotechnology

... Bacteria  Bacteria review one-celled prokaryotes  reproduce by mitosis ...
Mutations Activity
Mutations Activity

... Introduction: DNA is genetic material made of nucleotides. Last unit we saw how proteins were created through transcription (DNAmRNA) and translation (mRNAlinked amino acids). However, in this unit we want to see how those processes can “go wrong” and create mutations. In this activity you will in ...
Structure of the human DNA repair gene HAP1 and its localisation to
Structure of the human DNA repair gene HAP1 and its localisation to

... in the human genome with a size of —2.6 kb from the site of transcription initiation to the site of polyadenylation. This is principally because the gene contains only four introns of which three are less than 220 bp in length. One of these introns lies within the 5' non-coding region and thus the A ...
mc2 Genome_Organization
mc2 Genome_Organization

... generally resolves them into 3 sections: highly repeated DNA, moderately repeated DNA, and unique DNA. Each component has its own Cot1/2 value and represents a characteristic portion of the genome. – highly repeated DNA: average of 50,000 copies per genome, about 10% of total DNA – moderately repeat ...
Lab - TeacherWeb
Lab - TeacherWeb

...  Sort the DNA nucleotides into 4 separate piles according to their nitrogenous base and count them. Check the front of the envelope to be sure they are all there. Let your teacher know if you are missing any nucleotides. ...
Genetics-Essentials-Concepts-and-Connections
Genetics-Essentials-Concepts-and-Connections

... 18. The theory of pangenesis states that the inheritance of acquired characteristics during one’s lifetime cannot be passed on to offspring. (F) 19. Many human traits, such as skin and hair color, exhibit blending inheritance, in which genetic information is mixed and is not separated in future gene ...
Chapter Outline
Chapter Outline

... b. Methylation of DNA accounts for a phenomenon called genomic imprinting: gene expression is dependent on whether the chromosome carrying the gene is inherited from the mother or the father. c. Epigenetic inheritance explains unusual inheritance patterns, and may have implications in growth, aging, ...
25 M B I
25 M B I

... the chromosome has to decompact before transcription can begin. Transcription factors attach to DNA and turn on particular genes. In molecular terms, a gene is a segment of DNA, and a mutation is a change in the normal sequence of nucleotides of this segment. Frameshift mutations result when a base ...
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Helitron (biology)

A helitron is a transposon found in eukaryotes that is thought to replicate by a so-called ""rolling-circle"" mechanism. This category of transposons was discovered by Vladimir Kapitonov and Jerzy Jurka in 2001. The rolling-circle process begins with a break being made at the terminus of a single strand of the helitron DNA. Transposase then sits at this break and at another break where the helitron targets as a migration site. The strand is then displaced from its original location at the site of the break and attached to the target break, forming a circlular heteroduplex. This heteroduplex is then resolved into a flat piece of DNA via replication. During the rolling-circle process, DNA can be replicated beyond the initial helitron sequence, resulting in the flanking regions of DNA being ""captured"" by the helitron as it moves to a new location.
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