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ppt - Chair of Computational Biology
ppt - Chair of Computational Biology

... sequence length polymorphisms, SSLP, or microsatellites) are highly polymorphic loci present in DNA consisting of short 2-4 bp long sequence motifs repeating multiple times embedded in DNA with unique sequences. ...
final exam in kje-2004
final exam in kje-2004

... Question 4. Gene and promoter prediction (6 points) With the rapid generation of sequences generated from the “Next Generation Sequencing (NGS)”machines there is an increasing need to use bioinformatics approaches to accurately predict gene structure. a) (2p) Name and describe briefly the different ...
Phage Lab III - Generic Genome Browser of WUSTL Phages
Phage Lab III - Generic Genome Browser of WUSTL Phages

... 00002  prediction  around  450-­‐900  or  Glimmer  00003  in  the  region  from  800  –  1100.   Gene  2  is  easy,  Gene  3  a  little  more  challenging.  For  your  chosen  region  collect  the   relevant  information  by  filling ...
Duncan memorial lecture Medical genetics, the human genome
Duncan memorial lecture Medical genetics, the human genome

... competitiveness with collaboration to achieve results. More recently, industrial partners have shown increasing interest in this field. The purpose of the human genome project is to find genes and describe what they do. This is an important distinction from some of the previous approaches to genetic ...
MCB5472_Lecture_2_Feb-3-14
MCB5472_Lecture_2_Feb-3-14

... Founded in 1982 at the Los Alamos National Laboratory Initially managed at Stanford in conjunction with the BIOSCI/Bionet news groups 1989-92 transition to the NCBI on the east coast One precursor was Margaret Dayhoff’s Atlas of Protein Sequence and Structure In 1987 genbank fit onto a few 360 KB fl ...
Section 13-2
Section 13-2

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On Vacating the Conviction

... Westchester County Forensic Laboratory was the only course of action consistent with maintaining the fundamental tenets of justice and the integrity of the criminal justice system. Since 1999-2000, the Westchester County Forensic Lab routinely performs STR DNA analysis on evidence collected in homic ...
Name that Gene Project The National Center for Biotechnology
Name that Gene Project The National Center for Biotechnology

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... Damage may occur at any time in any cell. Errors during chromosome replication happen only about once in 100,000 bases. Given that the human genome has about 6 billion bases, this means each replication cycle will have 60,000 errors associated with it. Cells contain several complex systems to fix da ...
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Study Questions 2
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... DNA in cells deviates from the ideal B form by having increased overall pitch, with an average of approximately 10.5 base pairs per turn instead of 10 in the ideal B form. In addition, DNA in solution is irregular, including deviations at the level of the co-planarity of the base pairs (propeller tw ...
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... 2) Gargle and swish all the salty water (3 Tbsp water, 1 Tbsp salt) from the cup around your mouth. Do not swallow the water! Spit it back into the cup. 3) Dip the stir-stick in the dishwashing detergent and gently stir it in the cup. Less froth in the cup is better so stir only two or three times. ...
Exam3-1406_Fall2007ch9-10-11.doc
Exam3-1406_Fall2007ch9-10-11.doc

... 16) It became apparent to Watson and Crick after completion of their model that DNA molecule could carry a vast amount of hereditary information in its A) sequence of bases. B) phosphate-sugar backbone. C) complementary base pairing. D) side groups of nitrogenous bases. E) different five-carbon suga ...
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7.1 Techniques for Producing and Analyzing DNA

... the wells where they were first injected. ...
University of York Department of Biology B. Sc Stage 1 Degree
University of York Department of Biology B. Sc Stage 1 Degree

... BIO00007C c) Three sequences, each containing either a single base-substitution, single base-insertion or single base-deletion compared to the wild-type sequence given above, are listed below. For each sequence state whether the consequence will be a frame-shift mutation, a non-sense mutation, a mi ...
CONTENTS DNA, RNA AND PROTEIN SYNTHESIS DNA
CONTENTS DNA, RNA AND PROTEIN SYNTHESIS DNA

... The leading strand is synthesized continuously but the opposite strand is copied in short bursts of about 1000 bases, as the lagging strand template becomes available. The resulting short strands are called Okazaki fragments (after their discoverers, Reiji and Tsuneko Okazaki). Bacteria have at leas ...
2.How can we clone something?
2.How can we clone something?

... a clone an organism which is genetically identical to another ...
Dr. Hieter`s Lecture
Dr. Hieter`s Lecture

... • 425 open reading frames were identified that displayed cell-cycle dependent fluctuations in transcript levels. • 40% were of unknown function. • 30% are located next to other cell-cycle transcribed genes (possible enhancer effect). • Correlation with known and unknown promoter elements. ...
DNA, RNA, and the Flow of Genetic Information
DNA, RNA, and the Flow of Genetic Information

... The building blocks of nucleic acids and the precursors of these building blocks play many other roles throughout the cell—for instance, as energy currency and as molecular signals. Consequently, it is important to be familiar with the nomenclature of nucleotides and their precursors. A unit consist ...
Trends and barriers to lateral gene transfer in prokaryotes
Trends and barriers to lateral gene transfer in prokaryotes

... synthetase phylogeny [60]. High donor–recipient genome similarity in Gram-negative bacteria from the Neisseriales or Pasteurellales orders could be due to frequent gene acquisition by transformation (Figure 1) leading to a high frequency of uptake signal sequences (USSs) in the genomes of both donor ...
Lecture 7 - School of Science and Technology
Lecture 7 - School of Science and Technology

... • As size of genomes varies dramatically from 10,000 bp for simple viruses up to several billion bp in higher animals and plants, the number of sequences covering the whole genome also varies very significantly 10 – 106. • DNA fragments presented in DB have not only very different lengths but also d ...
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Helitron (biology)

A helitron is a transposon found in eukaryotes that is thought to replicate by a so-called ""rolling-circle"" mechanism. This category of transposons was discovered by Vladimir Kapitonov and Jerzy Jurka in 2001. The rolling-circle process begins with a break being made at the terminus of a single strand of the helitron DNA. Transposase then sits at this break and at another break where the helitron targets as a migration site. The strand is then displaced from its original location at the site of the break and attached to the target break, forming a circlular heteroduplex. This heteroduplex is then resolved into a flat piece of DNA via replication. During the rolling-circle process, DNA can be replicated beyond the initial helitron sequence, resulting in the flanking regions of DNA being ""captured"" by the helitron as it moves to a new location.
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