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Diapositive 1 - Institut Pasteur
Diapositive 1 - Institut Pasteur

... ●Expansion of PE/PPE proteins in pathogenic mycobacteria seem to have been accompanied with functional divergence ● Although several members are homologous, there does not seem to be any compensatory effect. Thus, a high level of functional specialization could have been reached during evolution ...
GFP plasmid - Kiwi.mendelu.cz
GFP plasmid - Kiwi.mendelu.cz

... Plasmids are fragments of doublestranded DNA that can replicate independently of chromosomal DNA, and carry genes Their size is between 1,000-20,000 base pairs and they are stable long-term Origin of Replication (ORI) ...
Poster
Poster

... RNAP is an essential multi-subunit enzyme of living organisms that carries out the process of transcription. RNAP operates as a molecular machine with many distinct components contributing specific functions. Much of the amino acid sequence of the β’ subunit is highly conserved between different ...
MCB 371/372 - Gogarten Lab | UConn
MCB 371/372 - Gogarten Lab | UConn

... The output is written into a file called Hv1.sites.codeml_out (as directed by the control file). Point out log likelihoods and estimated parameter line (kappa and omegas) Additional useful information is in the rst file generated by the codeml ...
Unit 5: Cell Cycles and Genetics Self
Unit 5: Cell Cycles and Genetics Self

... C) Understand the role of repressor proteins and inducers. D) Describe how the lac operon works in bacteria. F) Describe what Hox genes are and why they occur in a wide variety of animals. ...
Self-Organizing Bio-structures
Self-Organizing Bio-structures

... • RNA chain directionality: 5'3' • Backbone carries charge (-e) on each nucleotide • Formation of an RNA structure requires cations ...
Introduction to Transcriptional Machinery
Introduction to Transcriptional Machinery

... Promoter Elements in E. Coli ...
Glossary - OpenStax CNX
Glossary - OpenStax CNX

... Two bases which form a "rung of the DNA (Denition: "DNA", p. 4) ladder." A DNA nucleotide (Denition: "NUCLEOTIDE", p. 7) is made of a molecule of sugar, a molecule of phosphoric acid, and a molecule called a base. The bases are the "letters" that spell out the genetic code. In DNA, the code letter ...
Chapter 9
Chapter 9

... The fragments are separated according to size by gel electrophoresis. Each band contains many copies of a particular DNA fragment. The bands are invisible but can be made visible by staining. ...
Phylogeny and Host Specificity of Psoroptic Mange Mites (Acarina
Phylogeny and Host Specificity of Psoroptic Mange Mites (Acarina

... sequences within individuals ticks. Paralogous ITS sequences can exist because ribosomal RNA genes (including ITS1) are found in multiple, tandemly repeated copies per haploid genome. Most researchers who use ribosomal RNA in systematic studies assume that these repeats are homogenized through the p ...
Trans-HHS Workshop: Diet, DNA Methylation
Trans-HHS Workshop: Diet, DNA Methylation

... Reduced dietary intake or low tissue/plasma levels of several nutrients have been associated with higher risk for developing cancer. Interestingly, many micronutrients and vitamins are indispensable in DNA metabolic pathways (1,11). Although most studies have been conducted in vitro and in animal mo ...
RNA and Protein Synthesis
RNA and Protein Synthesis

... produced by copying part of the nucleotide sequence of DNA into a complementary sequence in RNA Transcription requires the enzyme RNA polymerase—binds to DNA and separates the DNA strands. Then uses one strand of DNA as a template from which nucleotides are assembled into a strand of RNA ...
Transcription lecture notes
Transcription lecture notes

... In bacteria, frequently have groups of genes that are transcribed together on single mRNA (a polygenic or polycistronic mRNA. Such groups of genes called operons. An operon will be transcribe from a single promoter (a DNA sequence that denotes a transcription start site). ...
Alpaca Color Genetics - Able Oaks Ranch Alpacas
Alpaca Color Genetics - Able Oaks Ranch Alpacas

... some. Most traits are polygenic, meaning multiple genes in multiple places on chromosomes (even multiple chromosomes) are involved. In people, even eye color is influenced by more that one gene, (that is how we get hazel, green, etc). In alpacas, coat color is influenced by more than one gene at mo ...
Mutation in Gelsolin Gene in Finnish Hereditary Amyloidosis
Mutation in Gelsolin Gene in Finnish Hereditary Amyloidosis

... as familial amyloid polyneuropathy type IV (2), is an ageassociated systemic amyloidosis with lattice corneal dystrophy and progressive cranial neuropathy as the principal clinical manifestations (1, 3). It is found primarily in families residing in Southeastern Finland (4), but cases have also been ...
Ch. 10 Presentation
Ch. 10 Presentation

... does not code for any other amino acid, – nearly universal—the genetic code is shared by organisms from the simplest bacteria to the most complex plants and animals, and – without punctuation in that codons are adjacent to each ...
DNA Methylation Mechanisms and Analysis Methods to
DNA Methylation Mechanisms and Analysis Methods to

Activity 2.2.1: Gene Therapy Introduction
Activity 2.2.1: Gene Therapy Introduction

Chapter 10 Information Transfer in Cells Information Transfer in Cells
Chapter 10 Information Transfer in Cells Information Transfer in Cells

... • Several bases usually methylated • Each a.a. has at least one unique tRNA which carries the a.a. to the ribosome • 3'-terminal sequence is always CCA-a.a. • Aminoacyl tRNA molecules are the substrates of protein synthesis ...
Normalization between a pair of arrays
Normalization between a pair of arrays

... Some regulatory proteins play more general role in initiating transcription (for example the eukaryotic transcription factors of type II or the RNA polymerase itself that is essential for the transcription of all genes). It is considered that dedicated regulatory proteins are those that affect up to ...
The contribution of human DNA studies to the debate on Anglo
The contribution of human DNA studies to the debate on Anglo

... question of the scale of Anglo-Saxon migration. Ultimately, like any other form of archaeological evidence the data is open to different interpretations. Three of the four papers listed above, for example, use modern population samples only; the results they produce are statistical projections, theo ...
Chapter 10
Chapter 10

... molecules in prokaryotic versus eukaryotic cells. In prokaryotes, a single mRNA molecule may contain the information for the synthesis of several polypeptide chains within its nucleotide sequence. ...
Is there a code for protein–DNA recognition?
Is there a code for protein–DNA recognition?

... If the two distributions, P and Q, are similar in the high probability states then their relative entropy is close to zero. This formalisation makes clear the relation between the interaction energies and the specificity of a protein to certain DNA targets (‘‘DNA recognition’’). The lower the intera ...
Walk-thru of CAGE exercise
Walk-thru of CAGE exercise

... – Etc What if we want to compare two experiments? ...
Historical Development of the Concept of the Gene
Historical Development of the Concept of the Gene

... replaced the old one gene/one enzyme hypothesis. (An enzyme molecule can consist of a single polypeptide molecule, but usually it consists of several identical [homomultimer] or non-identical [heteromultimer] polypeptides). Thus, the problem was how the information encoded in DNA for the assembly of ...
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Helitron (biology)

A helitron is a transposon found in eukaryotes that is thought to replicate by a so-called ""rolling-circle"" mechanism. This category of transposons was discovered by Vladimir Kapitonov and Jerzy Jurka in 2001. The rolling-circle process begins with a break being made at the terminus of a single strand of the helitron DNA. Transposase then sits at this break and at another break where the helitron targets as a migration site. The strand is then displaced from its original location at the site of the break and attached to the target break, forming a circlular heteroduplex. This heteroduplex is then resolved into a flat piece of DNA via replication. During the rolling-circle process, DNA can be replicated beyond the initial helitron sequence, resulting in the flanking regions of DNA being ""captured"" by the helitron as it moves to a new location.
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