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A novel de novo frame-shift mutation of the EDA gene in a
A novel de novo frame-shift mutation of the EDA gene in a

... Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA ...
Reconstructing evolution: Gene transfer from plastids to the nucleus
Reconstructing evolution: Gene transfer from plastids to the nucleus

... projects/other/cp_list.html). Soon after this realization, elegant early experiments(1,2,3) paved the way for the current understanding of peptide import from the nucleo-cytoplasmic genetic compartment into the organelle.(4) An explanation of the observed nuclear control over the organelle within th ...
A Comparative Study on the Yield of DNA Extracted from Fresh
A Comparative Study on the Yield of DNA Extracted from Fresh

... DNA profiling is a highly conclusive, informative procedure in identification of biological specimens. In the current study, Quantification of DNA was done to detect the concentration of DNA in the samples. Quantity of DNA was calculated by taking the absorbance of samples at 260 nm by Spectrophotom ...
University of Groningen A Branched Biosynthetic Pathway Is
University of Groningen A Branched Biosynthetic Pathway Is

... Other than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons). Take-down policy If you believe that this d ...
Accuracy of DNA Repair During Replication in Saccharomyces
Accuracy of DNA Repair During Replication in Saccharomyces

... DNA bases. Mismatch repair proteins fix places along the doublestranded DNA and fix sequences or bases that are out of place. Mismatch repair proteins fix replication errors, much like the DNA polymerase repair proteins. These proteins differ from the DNA polymerases because MMR will repair breaks o ...
dna and it`s role in heredity
dna and it`s role in heredity

1305077113_457396
1305077113_457396

... information necessary for a cell to replicate and make proteins. The code of DNA is found within the sequence of nitrogenous bases. DNA sequences are unique to each individual (except an identical twin). The variations within noncoding parts of the DNA molecule are the basis for forensic identificat ...
Ch 07 Overview - Northwest ISD Moodle
Ch 07 Overview - Northwest ISD Moodle

... information necessary for a cell to replicate and make proteins. The code of DNA is found within the sequence of nitrogenous bases. DNA sequences are unique to each individual (except an identical twin). The variations within noncoding parts of the DNA molecule are the basis for forensic identificat ...
Analysis of the chondroitinase operon of Flavobacterium columnare
Analysis of the chondroitinase operon of Flavobacterium columnare

... – Recognize specific nucleotide sequences – Should create different sticky ends and analyze buffer compatibility ...
Proceedings Template - WORD
Proceedings Template - WORD

... Cytosine (C). The single strands of DNA pair up length wise in anti-parallel fashion to form a double strand. This double strand resembles the shape of a twisted ladder or a double helix (Figure 2). The process of combining two single strands into a double strand is known as ‘Annealing’. Similarly ...
Nucleotide Bias Causes a Genomewide Bias in the Amino Acid
Nucleotide Bias Causes a Genomewide Bias in the Amino Acid

... on individual genes in more detail, we decided to compare the two genomes with the most distinct nucleotide compositions available. We identified the genes in common between the genomes of the highly AT-rich genome of B. burgdorferi and the very GC-rich genome of M. tuberculosis in an analysis simil ...
PDF of article
PDF of article

... PvuRts1I family enzymes are classified as bacterial type IV modification-dependent restriction endonucleases and they are known to play an important role in defence against phage infection (Loenen & Raleigh, 2014). Several restriction endonucleases, such as McrBC, SauUSI and MspJI, have the ability ...
Novel Imprinted DLK1/GTL2 Domain on Human Chromosome 14
Novel Imprinted DLK1/GTL2 Domain on Human Chromosome 14

... constitute a novel imprinted domain on human chromosome 14. DLK1 encodes for a cell-surface transmembrane protein that contains EGF-like repeat motifs, whereas the GTL2 transcript lacks a significant open reading frame. Many imprinted genes have been shown to function in embryonic and fetal developm ...
Genome Databases and Open Access Resources
Genome Databases and Open Access Resources

... Contig ...
Bio II Ch 16 Molecular Basis of Inheritance
Bio II Ch 16 Molecular Basis of Inheritance

... function of DNA polymerase is to add nucleotides to the end of a growing DNA strand and proof-read • The strands that make up DNA are antiparallel. This means that the 5' to 3' direction of one strand runs counter to the 5' to 3' direction of the other strand. • This creates a problem at the replica ...
GPMiner: an integrated system for mining combinatorial cis
GPMiner: an integrated system for mining combinatorial cis

... stability is a structural property of the DNA duplex fragment. The minimum free energy of the DNA duplex is calculated based on hydrogen bonding of A-T and C-G pairs. Kanhere et al. demonstrated that DNA stability of promoter regions provides a much better clue than other features when determining t ...
Cauliflower Mosaic Viral Promoter
Cauliflower Mosaic Viral Promoter

... 35S promoter, and was thought to be due primarily to template switching during reverse transcription. This kind of recombination depends on sequence homology between the recombining partners as well as the action of virally encoded reverse transcriptase, and is expected to have little impact on nonh ...
The Function of the Hereditary Materials: Biological
The Function of the Hereditary Materials: Biological

... being the end product of the pathway. They form the enzyme catalysts that determine what reactions occur in cells, as well as ensuring the necessary coordination between these reactions. RNA in this scheme is left with a subsidiary role, acting mainly as a "messenger boy" to carry out the instructio ...
Homework 1 BSC 1010 Fall 2011
Homework 1 BSC 1010 Fall 2011

... to any of the course resources including the text, lecture notes, and Connect. In order to receive credit for this homework assignment you must enter and submit your final answers online through Connect before the due date. ...
Gene Regulation
Gene Regulation

... Global view of the gene regulatory landscape • The module density varies widely across the genome, with an average of four modules per 100 kb and a maximum of 44 modules per 100-kb window, covering from 0% to 55% of such a region. • As illustrated in the previous figure, some regions are rich in mo ...
Gene Section MLL (myeloid/lymphoid or mixed lineage leukemia) Atlas of Genetics and Cytogenetics
Gene Section MLL (myeloid/lymphoid or mixed lineage leukemia) Atlas of Genetics and Cytogenetics

... M5/M4 de novo and therapy related ANLL. Prognosis The prognosis may not be as poor as in other 11q23 leukaemias in de novo cases; very poor prognosis in secondary ANLL cases. Cytogenetics May be overlooked; often as a sole anomaly. Hybrid/Mutated Gene Variable breakpoints on both genes. Abnormal Pro ...
SiRNA and Epigenetic
SiRNA and Epigenetic

... molecules that interfere with the expression of genes. It has 2-nt overhangs on either end, including a 5' phosphate group and a 3' hydroxy (-OH) group.  They are produced as part of the RNA interference (RNAi) pathway by the enzyme Dicer.  They can also be exogenously (artificially) introduced by ...
Recent retrotransposition events have not affected
Recent retrotransposition events have not affected

... Expression divergence was calculated for ~9000 genes based on expression in five tissues (data from Khaitovich et al, Science, 2005) Expression divergence is the Euclidean distance between expression levels in one or more tissues ...
Chapter 3: Molecular Biology Problems
Chapter 3: Molecular Biology Problems

... Molecular Biology Problems If you were a molecular biologist, you would focus on biological molecules like DNA, RNA, and proteins. Although generally true, your work would overlap with other areas like genetics and biochemistry. In this chapter, we have given you problems that will allow you to exp ...
Rich Probabilistic Models for Genomic Data
Rich Probabilistic Models for Genomic Data

... Find parameter estimates which make observed data most likely General approach, as long as tractable likelihood function exists Can use all available information ...
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Helitron (biology)

A helitron is a transposon found in eukaryotes that is thought to replicate by a so-called ""rolling-circle"" mechanism. This category of transposons was discovered by Vladimir Kapitonov and Jerzy Jurka in 2001. The rolling-circle process begins with a break being made at the terminus of a single strand of the helitron DNA. Transposase then sits at this break and at another break where the helitron targets as a migration site. The strand is then displaced from its original location at the site of the break and attached to the target break, forming a circlular heteroduplex. This heteroduplex is then resolved into a flat piece of DNA via replication. During the rolling-circle process, DNA can be replicated beyond the initial helitron sequence, resulting in the flanking regions of DNA being ""captured"" by the helitron as it moves to a new location.
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