Chromosomal translocations deregulated BCL6
... officially adopted, see McAlpine et al., 1994). Rearrangements of the BCL6 gene have also been shown in cases lacking recognizable abnormalities of band 3q27 at the cytogenetic level. Several surveys of non-Hodgkin's lymphoma (NHL) panels reported similar frequencies in various NHL subtypes, i.e. 30 ...
... officially adopted, see McAlpine et al., 1994). Rearrangements of the BCL6 gene have also been shown in cases lacking recognizable abnormalities of band 3q27 at the cytogenetic level. Several surveys of non-Hodgkin's lymphoma (NHL) panels reported similar frequencies in various NHL subtypes, i.e. 30 ...
Bridging the transgenerational gap with epigenetic memory
... originally thought. In parallel, a growing body of work has revealed that exposure of parents to environmental stimuli could affect the phenotype of several generations of descendants, suggesting that changes in epigenetic modifications induced by environmental stimuli might be passed on to descenda ...
... originally thought. In parallel, a growing body of work has revealed that exposure of parents to environmental stimuli could affect the phenotype of several generations of descendants, suggesting that changes in epigenetic modifications induced by environmental stimuli might be passed on to descenda ...
The Johns Hopkins University - American University of Beirut
... • You need to understand the data they have, and how it is organized • There are often many ways to get to an answer. • Route to get there is not always obvious, but you need to think of alternatives and traps. • Use some query language – each system has its own. • Retrieve data in a specified forma ...
... • You need to understand the data they have, and how it is organized • There are often many ways to get to an answer. • Route to get there is not always obvious, but you need to think of alternatives and traps. • Use some query language – each system has its own. • Retrieve data in a specified forma ...
Disclosure All authors have no competing financial relationships to
... TLR7 in PBMCs, resulting in a trend of decreased downstream production of type I IFNs; whereas inhibition of miR-3148 has an opposite effect. ...
... TLR7 in PBMCs, resulting in a trend of decreased downstream production of type I IFNs; whereas inhibition of miR-3148 has an opposite effect. ...
Report Number of Nuclear Divisions in the Drosophila Blastoderm
... expression of CyclinB. Although the altered levels of RNA polymerase II in X161 mutants probably affect expression of many genes during oogenesis, these changes seem not to matter in functional terms, given the overall normal morphology and specific mutant phenotype. It is conceivable that transcrip ...
... expression of CyclinB. Although the altered levels of RNA polymerase II in X161 mutants probably affect expression of many genes during oogenesis, these changes seem not to matter in functional terms, given the overall normal morphology and specific mutant phenotype. It is conceivable that transcrip ...
Bayesian Learning of MicroRNA Targets from Sequence
... Despite rapid advances in discovering and characterizing miRNAs, significant questions remain. One major challenge is determining the complete set of functional miRNA targets on a genome-wide scale. Previous work has focused primarily on the genome-wide computational discovery of miRNA genes [6, 17] ...
... Despite rapid advances in discovering and characterizing miRNAs, significant questions remain. One major challenge is determining the complete set of functional miRNA targets on a genome-wide scale. Previous work has focused primarily on the genome-wide computational discovery of miRNA genes [6, 17] ...
Knockdown of Parhyale Ultrabithorax - IMBB
... developed a strategy to knock down gene function during Parhayle development using injection of siRNAs, a technique effective in several diverse animal taxa. To demonstrate the efficacy of this technique in Parhyale, we chose the Dll gene as a positive control. Dll and its vertebrate homologs, the D ...
... developed a strategy to knock down gene function during Parhayle development using injection of siRNAs, a technique effective in several diverse animal taxa. To demonstrate the efficacy of this technique in Parhyale, we chose the Dll gene as a positive control. Dll and its vertebrate homologs, the D ...
PHANTASTICA Regulates Development of the Adaxial Mesophyll in
... show disruptions in adaxial/abaxial symmetry and differentiation of adaxial blade cell types in the abaxial domain (Lin et al., 2003). Further studies on PHAN in Antirrhinum revealed that it coded for a MYB-containing transcription factor involved not only in leaf polarity but also in elaboration of ...
... show disruptions in adaxial/abaxial symmetry and differentiation of adaxial blade cell types in the abaxial domain (Lin et al., 2003). Further studies on PHAN in Antirrhinum revealed that it coded for a MYB-containing transcription factor involved not only in leaf polarity but also in elaboration of ...
Powerpoint template for scientific posters (Swarthmore College)
... The systematic and comprehensive screen of 3L have confirmed 9 regions that are interacting with runt. In the future, we will do the specificity tests with NGT40+A system to increase the ectopic expression of runt. We will also do the in situ hybridization on the other interesting regions to see the ...
... The systematic and comprehensive screen of 3L have confirmed 9 regions that are interacting with runt. In the future, we will do the specificity tests with NGT40+A system to increase the ectopic expression of runt. We will also do the in situ hybridization on the other interesting regions to see the ...
WEREWOLF, a Regulator of Root Hair Pattern
... sufficient for flowering, the FT level is strictly regulated by diverse genes. In this study, we show that WEREWOLF (WER), a MYB transcription factor regulating root hair pattern, is another regulator of FT. The mutant wer flowers late in long days but normal in short days and shows a weak sensitivi ...
... sufficient for flowering, the FT level is strictly regulated by diverse genes. In this study, we show that WEREWOLF (WER), a MYB transcription factor regulating root hair pattern, is another regulator of FT. The mutant wer flowers late in long days but normal in short days and shows a weak sensitivi ...
The full-length HIV-1 molecular clone pLAI 61 was used to produce
... 1. Peden K, Emerman M, Montagnier L. Changes in growth properties on passage in tissue culture of viruses derived from infectious molecular clones of HIV-1LAI, HIV-1MAL, and HIV-1ELI. Virol 1991; 185: 661-672. 2. Klaver B, Berkhout B. Comparison of 5' and 3' long terminal repeat promoter function in ...
... 1. Peden K, Emerman M, Montagnier L. Changes in growth properties on passage in tissue culture of viruses derived from infectious molecular clones of HIV-1LAI, HIV-1MAL, and HIV-1ELI. Virol 1991; 185: 661-672. 2. Klaver B, Berkhout B. Comparison of 5' and 3' long terminal repeat promoter function in ...
Epigenetics & Chromatin Xist through transcriptional control of Dnmt3a
... X chromosome inactivation is the mechanism used in mammals to achieve dosage compensation of X-linked genes in XX females relative to XY males. Early in development all cells in female embryos inactivate most genes on one of the two X chromosomes. In embryonic lineages X inactivation is normally ran ...
... X chromosome inactivation is the mechanism used in mammals to achieve dosage compensation of X-linked genes in XX females relative to XY males. Early in development all cells in female embryos inactivate most genes on one of the two X chromosomes. In embryonic lineages X inactivation is normally ran ...
Expression of Allene Oxide Synthase Determines - Bio
... concurrence with the presence of internal restriction sites for these enzymes within the cDNA sequence. The expression of the gene was highest in flowers, with low amounts of transcript being present in stem and root (Fig. 2b). In leaves and fruits, AOS mRNA was not detectable under non-inducing con ...
... concurrence with the presence of internal restriction sites for these enzymes within the cDNA sequence. The expression of the gene was highest in flowers, with low amounts of transcript being present in stem and root (Fig. 2b). In leaves and fruits, AOS mRNA was not detectable under non-inducing con ...
Regulation of Na/K-ATPase β1 -subunit gene
... beneficial adaptive response to increased workload, but also an independent risk factor for the development of heart failure [17]. Hence, it is important to study the potential hypertrophic effects of drugs that are widely used in the treatment of heart failure. Since the enzyme serves as a receptor ...
... beneficial adaptive response to increased workload, but also an independent risk factor for the development of heart failure [17]. Hence, it is important to study the potential hypertrophic effects of drugs that are widely used in the treatment of heart failure. Since the enzyme serves as a receptor ...
Chapter 13 - Microbial Genetics
... D) The lac operon will be induced only when both glucose and lactose are present E) The lac operon will be induced only when glucose is present and lactose is absent ...
... D) The lac operon will be induced only when both glucose and lactose are present E) The lac operon will be induced only when glucose is present and lactose is absent ...
... The Atlas of Genetics and Cytogenetics in Oncology and Haematology is a peer reviewed on-line journal in open access, devoted to genes, cytogenetics, and clinical entities in cancer, and cancer-prone diseases. It presents structured review articles (“cards”) on genes, leukaemias, solid tumours, canc ...
Natural variation in nucleolar dominance reveals
... was derived from a plant of accession 90-10-085-10 (originating in Finland). Laboratory strain 94-53 was derived from a plant of accession 94-53-30-94-00 (collected in a botanical garden in Goettingen, Germany; the original location of the wild population is unknown). Plants of accessions 90-10-085- ...
... was derived from a plant of accession 90-10-085-10 (originating in Finland). Laboratory strain 94-53 was derived from a plant of accession 94-53-30-94-00 (collected in a botanical garden in Goettingen, Germany; the original location of the wild population is unknown). Plants of accessions 90-10-085- ...
Respiratory terminal oxidases in the facultative chemoheterotrophic
... microns, Sigma-Aldrich) for 4 min. Two-step RT-PCR was performed using the enhanced avian RT-PCR kit (SigmaAldrich). Total RNA was denatured together with the specific primer for 10 min at 85 8C and the reverse transcriptase reaction was performed for 40 min at 48 8C followed by 20 min at 60 8C. PCR ...
... microns, Sigma-Aldrich) for 4 min. Two-step RT-PCR was performed using the enhanced avian RT-PCR kit (SigmaAldrich). Total RNA was denatured together with the specific primer for 10 min at 85 8C and the reverse transcriptase reaction was performed for 40 min at 48 8C followed by 20 min at 60 8C. PCR ...
Consulta: subjectFacets:"Oviduct" Registros recuperados: 17 Data
... Intra-oviductal administration of RNA obtained from oviducts of estradiol-treated rats resulted in accelerated egg transport (<A HREF="#rios97">Ríos et al., 1997</A>). It is probable that estradiol-induced messenger RNA (mRNA) entered oviductal cells and was translated into the proteins ...
... Intra-oviductal administration of RNA obtained from oviducts of estradiol-treated rats resulted in accelerated egg transport (<A HREF="#rios97">Ríos et al., 1997</A>). It is probable that estradiol-induced messenger RNA (mRNA) entered oviductal cells and was translated into the proteins ...
Table of Contents - Scholars` Bank
... amino acids that could somehow use the template of the nucleotide encoded within mRNA to distinguish which amino acid was required to construct the desired protein. However, before the “adaptor” could be found, the specifics of the genetic code became known. F. H. C. Crick, J. S. Griffith and L. E. ...
... amino acids that could somehow use the template of the nucleotide encoded within mRNA to distinguish which amino acid was required to construct the desired protein. However, before the “adaptor” could be found, the specifics of the genetic code became known. F. H. C. Crick, J. S. Griffith and L. E. ...
Control of Lysogenization by Phage P22. II. Mutations (clyA) in the c1 Gene that Cause Increased Lysogenization
... FIG:. I. Fine structure map of the P22 cl gene. All mutations were mapped by 4-factor reciprocal crosses (see text). The genes O-O, cl and 1X are expressed rightward from the p, promoter, as are the genes I;! and 24 (not shown, see Susskind AZBotstein. 1978). The r2 gene is normally expressed leftwa ...
... FIG:. I. Fine structure map of the P22 cl gene. All mutations were mapped by 4-factor reciprocal crosses (see text). The genes O-O, cl and 1X are expressed rightward from the p, promoter, as are the genes I;! and 24 (not shown, see Susskind AZBotstein. 1978). The r2 gene is normally expressed leftwa ...
PhytoREF: a reference database of the plastidial 16S
... rRNA gene has been successfully employed in several marine surveys since it contains sufficiently conserved regions to use generalist primers to target all plastid-bearing eukaryotes and can distinguish major eukaryotic lineages with a relatively good taxonomic resolution (Fuller et al. 2006; MacDon ...
... rRNA gene has been successfully employed in several marine surveys since it contains sufficiently conserved regions to use generalist primers to target all plastid-bearing eukaryotes and can distinguish major eukaryotic lineages with a relatively good taxonomic resolution (Fuller et al. 2006; MacDon ...
The Mycobacterium tuberculosis katG promoter region contains a
... restriction sites present in the insert. These are summarized in Table 1 and Fig. 2. The construct pANIIIW (a gift from Karen Kempsall, Glaxo-Wellcome), consisting of a 170 bp PCR fragment containing the PAN promoter cloned into the T-tailed EcoRV restriction site of the vector pT7Blue (Novagen), wa ...
... restriction sites present in the insert. These are summarized in Table 1 and Fig. 2. The construct pANIIIW (a gift from Karen Kempsall, Glaxo-Wellcome), consisting of a 170 bp PCR fragment containing the PAN promoter cloned into the T-tailed EcoRV restriction site of the vector pT7Blue (Novagen), wa ...
Non-coding RNA
A non-coding RNA (ncRNA) is an RNA molecule that is not translated into a protein. Less-frequently used synonyms are non-protein-coding RNA (npcRNA), non-messenger RNA (nmRNA) and functional RNA (fRNA). The DNA sequence from which a functional non-coding RNA is transcribed is often called an RNA gene.Non-coding RNA genes include highly abundant and functionally important RNAs such as transfer RNAs (tRNAs) and ribosomal RNAs (rRNAs), as well as RNAs such as snoRNAs, microRNAs, siRNAs, snRNAs, exRNAs, and piRNAs and the long ncRNAs that include examples such as Xist and HOTAIR (see here for a more complete list of ncRNAs). The number of ncRNAs encoded within the human genome is unknown; however, recent transcriptomic and bioinformatic studies suggest the existence of thousands of ncRNAs., but see Since many of the newly identified ncRNAs have not been validated for their function, it is possible that many are non-functional. It is also likely that many ncRNAs are non functional (sometimes referred to as Junk RNA), and are the product of spurious transcription.