Neurotrophin Receptor Genes Are Expressed in Distinct Patterns in
... A fundamental advance in the understanding of how growth factors act in the developing nervous system has occurred with the identification of receptors that mediate the biological actions of the neurotrophin family of neuronal growth factors (Klein et al., 1989, 1990, 199 1; Martin-Zanca et al., 199 ...
... A fundamental advance in the understanding of how growth factors act in the developing nervous system has occurred with the identification of receptors that mediate the biological actions of the neurotrophin family of neuronal growth factors (Klein et al., 1989, 1990, 199 1; Martin-Zanca et al., 199 ...
PDF - Oxford Academic - Oxford University Press
... sequential replicas were used to investigate the phyllotaxis and geometry of shoot apices, and growth of the young stem surface. The expression pattern of CUC3 was analysed by examining its promoter activity. Key Results Phyllotaxis irregularity in the cuc2 cuc3 double mutant arises during the pos ...
... sequential replicas were used to investigate the phyllotaxis and geometry of shoot apices, and growth of the young stem surface. The expression pattern of CUC3 was analysed by examining its promoter activity. Key Results Phyllotaxis irregularity in the cuc2 cuc3 double mutant arises during the pos ...
Document
... In the airway In the blood Different genes Different mediators ……….…different disease ? ...
... In the airway In the blood Different genes Different mediators ……….…different disease ? ...
Trans-acting siRNA-mediated repression of ETTIN
... that abaxial trichome production is sensitive to the dose of ETT. In summary, these results indicate that ETT and ARF4 promote the expression of at least two juvenile traits – ‘circular/elliptical’ leaf morphology and the absence of abaxial trichomes – and are required for the effect of zip-2 on the ...
... that abaxial trichome production is sensitive to the dose of ETT. In summary, these results indicate that ETT and ARF4 promote the expression of at least two juvenile traits – ‘circular/elliptical’ leaf morphology and the absence of abaxial trichomes – and are required for the effect of zip-2 on the ...
Gene Ontology (GO) Tutorial
... over the available literature and has found that none of it is adequate to assign a term. A good example is Dab2ip. As shown by it’s annotation summary, there was literature to demonstrate that it bound a protein, but no literature to suggest what process it participated in or where in the cell it w ...
... over the available literature and has found that none of it is adequate to assign a term. A good example is Dab2ip. As shown by it’s annotation summary, there was literature to demonstrate that it bound a protein, but no literature to suggest what process it participated in or where in the cell it w ...
Pharmacogenetics of warfarin: current status and future
... Based on an inhibition assay, there is some evidence that the transport of warfarin across plasma membranes of cells, for example in the liver, may be mediated by P-glycoprotein (multidrug resistance protein 1), which is encoded by ABCB1 (MDR1; ATP-binding cassette transporter B1 gene).18 However, t ...
... Based on an inhibition assay, there is some evidence that the transport of warfarin across plasma membranes of cells, for example in the liver, may be mediated by P-glycoprotein (multidrug resistance protein 1), which is encoded by ABCB1 (MDR1; ATP-binding cassette transporter B1 gene).18 However, t ...
Attachment 2.2 Sequencing results
... tumour initiation and progression. [19-22] The TCDD-dependant release from contact inhibition seems to be a common phenomenon as it is observed in several cell lines. [23] In the human breast cancer epithelial cell line MCF-7 a down regulation of E-cadherin (a transmembrane protein playing an import ...
... tumour initiation and progression. [19-22] The TCDD-dependant release from contact inhibition seems to be a common phenomenon as it is observed in several cell lines. [23] In the human breast cancer epithelial cell line MCF-7 a down regulation of E-cadherin (a transmembrane protein playing an import ...
Mutations at the Darkener of apricot Locus Modulate Transcript
... to T 4 and produces a truncated mRNA. T h e resultant protein retains activity, and this allele is classified as a hypermorph, which is due to an overaccumulation of T 4 mRNA (CAMPUZANO et al. ...
... to T 4 and produces a truncated mRNA. T h e resultant protein retains activity, and this allele is classified as a hypermorph, which is due to an overaccumulation of T 4 mRNA (CAMPUZANO et al. ...
... Acetoin is a four carbon acetohydroxy compound that is synthesized in all simple bacteria, plants and animals, as the by-product of branched chain amino acid synthesis. Organisms such as Klebsiella and Bacillus synthesize acetoin during late exponential phase of the growth by alsSD operon. The alsSD ...
Biology 30
... Hip dysplasia, a defect in the hip joints that can cripple a dog, occurs in 60% of golden retrievers. ...
... Hip dysplasia, a defect in the hip joints that can cripple a dog, occurs in 60% of golden retrievers. ...
Building Individualized Medicine: Prevention of Adverse Reactions
... the same set of functionally important polymorphisms, which in reality is rarely achieved. Whereas functional studies proved to be efficient in analysis of single genes, association studies hold great promise in identifying multiple alleles contributing to polygenic traits. A clinically important ex ...
... the same set of functionally important polymorphisms, which in reality is rarely achieved. Whereas functional studies proved to be efficient in analysis of single genes, association studies hold great promise in identifying multiple alleles contributing to polygenic traits. A clinically important ex ...
Life Sciences
... by means of the Krebs cycle while also providing some re-synthesis to glucose or glycogen. Increasing the supply of phosphate would be ineffective as the essential feature of muscular action is the use of energy-providing reactions in which the enrgy is ultimately derived from carbohydrate by anaero ...
... by means of the Krebs cycle while also providing some re-synthesis to glucose or glycogen. Increasing the supply of phosphate would be ineffective as the essential feature of muscular action is the use of energy-providing reactions in which the enrgy is ultimately derived from carbohydrate by anaero ...
redundancy and regulatory interactions between two
... FAR cDNA clones showed that four utilized the alternative splice site. The variation occurs within a region of the MADS-box protein known as the I-domain (Ma et al., 1991), the length and sequence composition of which have been postulated to affect the heterodimerization specificity amongst MADS-box ...
... FAR cDNA clones showed that four utilized the alternative splice site. The variation occurs within a region of the MADS-box protein known as the I-domain (Ma et al., 1991), the length and sequence composition of which have been postulated to affect the heterodimerization specificity amongst MADS-box ...
Complex Heterozygosity Screening with Actin Alanine Scan Alleles
... et al. 2008); however, identification of the genetic determinants in genetically complex disorders has been elusive, a problem referred to as “missing heritability” (Queitsch et al. 2012) or “phantom heritability” (Zuk et al. 2012). We believe that studies in model systems can illuminate aspects of m ...
... et al. 2008); however, identification of the genetic determinants in genetically complex disorders has been elusive, a problem referred to as “missing heritability” (Queitsch et al. 2012) or “phantom heritability” (Zuk et al. 2012). We believe that studies in model systems can illuminate aspects of m ...
Help Me Understand Genetics
... This process uses oxygen and simple sugars to create adenosine triphosphate (ATP), the cell’s main energy source. A set of enzyme complexes, designated as complexes I-V, carry out oxidative phosphorylation within mitochondria. In addition to energy production, mitochondria play a role in several oth ...
... This process uses oxygen and simple sugars to create adenosine triphosphate (ATP), the cell’s main energy source. A set of enzyme complexes, designated as complexes I-V, carry out oxidative phosphorylation within mitochondria. In addition to energy production, mitochondria play a role in several oth ...
The Nicotiana tabacum genome encodes two cytoplasmic
... DNA digested with EcoRI indicates that there is approximately one gene copy per haploid genome. The band patterns and intensity of hybridization can be consistently interpreted to give a total per genome of two genes which are homologous to thioredoxin h,. Isolation and characterization of a genomic ...
... DNA digested with EcoRI indicates that there is approximately one gene copy per haploid genome. The band patterns and intensity of hybridization can be consistently interpreted to give a total per genome of two genes which are homologous to thioredoxin h,. Isolation and characterization of a genomic ...
Imprinting in the endosperm: a possible role in preventing wide
... tissue with an unequal parental genomic contribution, which, like the placenta of mammals, provides reserves to the developing embryo. Interestingly, many aspects of endosperm development, again like the placenta, are regulated by a range of epigenetic mechanisms that are globally termed imprinting. ...
... tissue with an unequal parental genomic contribution, which, like the placenta of mammals, provides reserves to the developing embryo. Interestingly, many aspects of endosperm development, again like the placenta, are regulated by a range of epigenetic mechanisms that are globally termed imprinting. ...
Recruitment of CRABS CLAW to promote nectary development
... perianth positions in basal taxa to central positions associated with reproductive organs in more derived taxa. In addition, extrafloral nectaries are currently known in 68 angiosperm families (Elias, 1983). Their structures and locations are also diverse across the families, although they occur mos ...
... perianth positions in basal taxa to central positions associated with reproductive organs in more derived taxa. In addition, extrafloral nectaries are currently known in 68 angiosperm families (Elias, 1983). Their structures and locations are also diverse across the families, although they occur mos ...
Expert Reviews in Molecular Medicine Androgenetic alopecia
... receptor, a member of the steroid-thyroid hormone nuclear receptor superfamily. The structure of the androgen receptor includes a ligand-binding domain and a DNA-binding domain. Both testosterone and DHT can bind to the ligand domain, which activates the DNAbinding domain. The receptor–ligand comple ...
... receptor, a member of the steroid-thyroid hormone nuclear receptor superfamily. The structure of the androgen receptor includes a ligand-binding domain and a DNA-binding domain. Both testosterone and DHT can bind to the ligand domain, which activates the DNAbinding domain. The receptor–ligand comple ...
DNA supercoiling factor contributes to dosage
... dramatic reduction in the viability of males carrying both GAL4 and UAS-IRscf (Fig. 1B). Most of these males died during the pupal stage, and the few individuals that did survive to adulthood died shortly after eclosion. The effects on male viability do not appear to be due to position effects, as t ...
... dramatic reduction in the viability of males carrying both GAL4 and UAS-IRscf (Fig. 1B). Most of these males died during the pupal stage, and the few individuals that did survive to adulthood died shortly after eclosion. The effects on male viability do not appear to be due to position effects, as t ...
DETERMINATION AND POLARITY
... required for oocyte determination. First, the Egl and BicD proteins colocalize within the egg and this localization requires the function of both genes. Second, the penetrance of BicD dominant mutations can be altered by changing the egl gene dosage, showing a genetic interaction between the loci. T ...
... required for oocyte determination. First, the Egl and BicD proteins colocalize within the egg and this localization requires the function of both genes. Second, the penetrance of BicD dominant mutations can be altered by changing the egl gene dosage, showing a genetic interaction between the loci. T ...
The development and evolutionary origin of barbels in
... members of the Bone morphogenetic protein (Bmp), Distal-less (Dlx), Fibroblast growth factor (Fgf), Hedgehog (Hh), Tumor necrosis factor (Tnf), and Tnf receptor families. Other genes with roles in appendage development were absent from barbels, however, including members of the Dachshund (Dach) and ...
... members of the Bone morphogenetic protein (Bmp), Distal-less (Dlx), Fibroblast growth factor (Fgf), Hedgehog (Hh), Tumor necrosis factor (Tnf), and Tnf receptor families. Other genes with roles in appendage development were absent from barbels, however, including members of the Dachshund (Dach) and ...
Analysis of large and small colony L5178Y tk−/− mouse lymphoma
... idiogram is shown aligned with the linkage map for orientation, although the correlation of physical and genetic maps in mouse is inexact. The number of large and small colony mutants in each LOH category examined are shown arrayed along chromosome 11 to provide an illustration of the distribution o ...
... idiogram is shown aligned with the linkage map for orientation, although the correlation of physical and genetic maps in mouse is inexact. The number of large and small colony mutants in each LOH category examined are shown arrayed along chromosome 11 to provide an illustration of the distribution o ...
mic.sgmjournals.org
... common modification in biologically active natural peptides and is thought to improve stability against proteolytic degradation (Finking & Marahiel, 2004; Sieber & Marahiel, ...
... common modification in biologically active natural peptides and is thought to improve stability against proteolytic degradation (Finking & Marahiel, 2004; Sieber & Marahiel, ...
Retrotransposon-Mediated Fgf5go-Utr Mutant Mice
... FGF5 is an important factor in regulation of the hair follicle cycle, it is not clear whether or not FGF5 is involved in human diseases. Recently, a genome-wide association study, using very large study samples of European ancestry from the Global Blood Pressure Genetics consortium, identified FGF5 ...
... FGF5 is an important factor in regulation of the hair follicle cycle, it is not clear whether or not FGF5 is involved in human diseases. Recently, a genome-wide association study, using very large study samples of European ancestry from the Global Blood Pressure Genetics consortium, identified FGF5 ...