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Generation time
Generation time

... • This lag in division is associated with a physiological adaptation to the new environment. • Cells may increase in size during this time, but simply do not divide (by binary fission). • Lag phase varies considerably in length depending upon the condition of the microorganisms and the nature of the ...
What was the illness?
What was the illness?

... 1. Groups of microorganisms have common characteristics, and these characteristics enable them to interact with other organisms in the environment. 2. Microorganisms can have both positive and negative effects on the environment. 3. The technological use of microorganisms raises many ethical issues. ...
Alyson Zwickera, Tess Robartsa, Purvi Trivedia, Rattina
Alyson Zwickera, Tess Robartsa, Purvi Trivedia, Rattina

... Glycosylation is the cellular process of enzymatic addition of sugars to protein, forming complex glycoproteins that are vital for cellular function. In the endoplasmic reticulum (ER), during the N-glycosylation process (see Figure 1), ALG9 also known as α1,2mannosyltransferase facilitates the addit ...
eCSI case discussion
eCSI case discussion

... • Flow cytometric immunophenotyping was performed on the bone marrow aspirate and the results from selected 8-color tubes are provided for review. ...
26 - Rutgers Chemistry
26 - Rutgers Chemistry

... also called a neoplasm, is any abnormal proliferation of cells which may be benign or malignant. A benign tumor stays confined to its original location; it neither invades neighboring normal tissue nor spreads to distant body sites. On the other hand, a malignant tumor is able to both invade neighbo ...
Identification of rare cancer driver mutations by network reconstruction
Identification of rare cancer driver mutations by network reconstruction

... • Previous efforts to detect rare driver mutations have focused on known pathways or known direct interactions between mutated genes, resulting in descriptions of tumorigenic processes in very general terms, and hence, lack specificity with respect to the role of specific mutations in the tumorigeni ...
ppt - Chair of Computational Biology
ppt - Chair of Computational Biology

... the activation and repression of transcription is required. This is ensured by regulation through post-translational modifications. ...
Statistical Applications in Biology and Genetics
Statistical Applications in Biology and Genetics

... Sample project II: BHTA algorithm for complex traits ...
Pair rule genes also encode TFs
Pair rule genes also encode TFs

... Expression Patterns Trithorax-group: Maintain homeotic genes in ON state. Maintain active chromatin structure. Polycomb-group: Maintain transcriptional SILENCE of homeotic genes. Maintain repressive chromatin structure. Both involve covalent modifications of histones. ...
Meiosis Quick Notes
Meiosis Quick Notes

... Name: _______________________________________ Period:_______________________________________ Date: _______________________________________ Notes: Two types of reproduction (making more of you): 1. Asexual reproduction → a single parent reproduces by itself – Parent and offspring (child) are genetica ...
Medical Symposium
Medical Symposium

... Consider:  We get all of our traits from all the generations before us.  Naturally, we each have our own probability of something in our body not working as it should the second we are born.  These include diseases we can get, to small things like poor sight. ...
Cloning a -cateninY654E-fl-neo targeting vector
Cloning a -cateninY654E-fl-neo targeting vector

... high fidelity DNA polymerase (Stratagene) was used to generate a 5.2 kb genomic fragment containing exons 7-11, and a 3.3 kb genomic fragment containing exons 12-15. Using site directed mutagenesis, the latter fragment was modified at amino acid residue 654 present within exon 13, to replace the ori ...
Whole Exome Sequencing
Whole Exome Sequencing

... child’s medical record. Therefore, these results will be available to your insurance company and may affect coverage and/or premiums (cost). Information about a person’s family history is used to interpret test results for genetic testing, including WES. If the family history is wrong or not accurat ...
The Third PowerPoint (DNA and Sex Determination)
The Third PowerPoint (DNA and Sex Determination)

... Alzheimer Disease • Individuals with Alzheimer disease lose the ability to create and keep memories. • This genetic disease is thought to be due to a combination of environmental and genetic effects. • Scientists do not know which genes affect Alzheimer Disease. • They hypothesize that a certain pr ...
Reporter constructs are a tool for studying gene regulation
Reporter constructs are a tool for studying gene regulation

... Large enhancer region of Drosophila string gene • Fourteenth cell cycle of the fruit fly embryo • A variety of enhancer regions ensure that string is turned on at the right time in each mitotic domain and tissue type ...
Final Review - Bishop Lynch High School
Final Review - Bishop Lynch High School

Supplementary Information - Molecular Cancer Therapeutics
Supplementary Information - Molecular Cancer Therapeutics

... indicated treatment conditions (n=2, mean±SD). 6-AA (1.25-10 nM) and vinblastine (10 nM) induced a significant increase in PHH3-positive cells when treated for after 8 h (orange bars). Longer treatment (24 h, purple bars) further increased the proportion of PHH3-positive cells. Removal of 6-AA and v ...
Reverse Engineering of Metazoan Gene Regulatory
Reverse Engineering of Metazoan Gene Regulatory

... Institute of Bioengineering, School of Life Sciences, EPFL, Switzerland Gene regulatory networks play a vital role in metazoan development and function. The protein-DNA interactions (PDIs) that form the basis of these networks have however been poorly characterized. The recent availability of the hu ...
Understanding how bacterial cells organise in
Understanding how bacterial cells organise in

... Such rod-shaped model organisms, which include Escherichia coli and Bacillus subtilis, have been used and studied extensively by a number of bacterial cell biologists, including Professor Bramkamp. A fundamental question that all cells need to deal with is the correct positioning of the cell divisio ...
Eukaryotes - Daniel Guetta
Eukaryotes - Daniel Guetta

... Some genes have associated SILENCERS First observed in the genome of SV40 - a sequence of ~100bp can significantly increase transcription from a basal promoter, even far upstream ...
Genetics - Our Lady Of The Wayside School
Genetics - Our Lady Of The Wayside School

... • Skin, hair, and eye color are based on many alleles ...
Gene Section HIP1 (huntingtin interactin protein 1) Atlas of Genetics and Cytogenetics
Gene Section HIP1 (huntingtin interactin protein 1) Atlas of Genetics and Cytogenetics

... Hybrid/Mutated Gene 5' HIP1- 3' PDGFRb. Abnormal Protein Nearly all of HIP1, including the leucine zipper and talin homology domains, is fused to the transmembrane and tyrosine kinase domain of the PDGFb. Oncogenesis Constitutive activation of PDGFb (by tyrosine autophosphorylation). ...
Solid Tumour Section Lung: non-small cell carcinoma with inv(2)(p21p23)
Solid Tumour Section Lung: non-small cell carcinoma with inv(2)(p21p23)

... In lung cancer cells, 5'-part of EML4 is fused to intron 19 of ALK, generating EML4-ALK. While intron 19 of ALK is involved in the rearrangement in most of the cases, breakpoints within EML4 may diverge, giving rise to various isoforms of EML4-ALK. Detailed information of known variants is shown bel ...
Slide 1
Slide 1

... carriers of the defective gene (two carriers have to mate to produce an affected individual). Why is the prevalence of this defect so high? ...
Genetics
Genetics

... • Here is what they look like when you see them through a microscope. ...
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NEDD9

Neural precursor cell expressed developmentally down-regulated protein 9 (NEDD-9) is a protein that in humans is encoded by the NEDD9 gene. NEDD-9 is also known as enhancer of filamentation 1 (EF1), CRK-associated substrate-related protein (CAS-L), and Cas scaffolding protein family member 2 (CASS2). An important paralog of this gene is BCAR1.
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