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Chapter 11: DNA and the Language of Life - Rebecca Waggett
Chapter 11: DNA and the Language of Life - Rebecca Waggett

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... down-regulation of the PTEN/PI3K/AKT/PKB signaling pathway. Lack of PTEN in a cell leads to accumulation of PIP3 that activates the AKT/ PKB signaling oncoprotein [37–39]. Active AKT modulates a number of downstream targets, which have important roles in the regulation of apoptosis and the cell cycl ...
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NEDD9

Neural precursor cell expressed developmentally down-regulated protein 9 (NEDD-9) is a protein that in humans is encoded by the NEDD9 gene. NEDD-9 is also known as enhancer of filamentation 1 (EF1), CRK-associated substrate-related protein (CAS-L), and Cas scaffolding protein family member 2 (CASS2). An important paralog of this gene is BCAR1.
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