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Document
Document

... • What are the structural genes in the lac operon? – z gene - encodes B-galactosidase – y gene - encodes galactoside permease; promotes lactose entry into cell – a gene - encodes thiogalactoside acetyltransferase; role is unclear ...
File
File

... The most common type is Red/Green Colorblindness. (Red and Green appear gray.) Hemophilia (Means “love of bleeding”) These individuals CANNOT make (recessive) Anti-hemolytic Factor. (AHF for short.) They may experience problems with possible bleeding to death. This was a disorder associated with the ...
I. Mutations: primary tools of genetic analysis
I. Mutations: primary tools of genetic analysis

... What mutations tell us about gene structure: a. Mutations within the same gene usually fail to complement each other. The concept of a complementation group thus defines the gene as a unit of function. b. A gene is composed of a linear sequence of nucleotides in a discrete, localized region of a chr ...
Coordinated repression and activation of two
Coordinated repression and activation of two

... somatic and visceral muscles (Giesen et al., 1997; Murawsky et al., 2001). We confirmed this observation and, in addition, found that Futsch is also misexpressed in the cardiac mesoderm (supplementary material Fig. S2), suggesting that ttk might be expressed at subdetectable levels in the heart and/ ...
Slides
Slides

... Functionally, a eukaryotic gene can be defined as being composed of a transcribed region (coding region) and of regions (regulatory region) that cis-regulate the gene expression, such as the promoter region which controls both the site and the extent of transcription. The currently existing gene pre ...
Stored fat fights against the body`s attempts to lose
Stored fat fights against the body`s attempts to lose

... Most of the fat cells in the body act to store excess energy and release it when needed but some types of fat cells, known as brown adipocytes, function primarily for a process known as thermogenesis, which generates heat to keep us warm. However, an international team of researchers from the Wellco ...
Ch8MicrobialGenetics
Ch8MicrobialGenetics

... Define genetics, genome, chromosome, gene, genetic code, genotype, phenotype, and genomics. Describe the process of DNA replication. Describe protein synthesis, including transcription, RNA processing, and translation. Classify mutations by type, and describe how mutations are prevented and repaired ...
Cell Biology and Genetics
Cell Biology and Genetics

... This disorder is caused by having an extra chromosome #21 and results in mental retardation, short stature and a shortened life ...
Ensembl. Going beyond A,T, G and C
Ensembl. Going beyond A,T, G and C

... • There are 4,418 TSS with multiple lines of evidence supporting them • This is ~10 fold more than the number of Genes • Only 38% would be traditionally classified as TSS (less if one took Ensembl or RefSeq) ...
PowerPoint file
PowerPoint file

... Define genetics, genome, chromosome, gene, genetic code, genotype, phenotype, and genomics. Describe the process of DNA replication. Describe protein synthesis, including transcription, RNA processing, and translation. Classify mutations by type, and describe how mutations are prevented and repaired ...
Jeopardy worksheet
Jeopardy worksheet

... 5 points: In rabbits, the allele for a spotted coat is ____________________ over the allele for a solid colored coat. A spotted rabbit was crossed with a solid color rabbit. The offspring all had spotted coats. What were the ________________ of the parents? Explain. Answer: ...
Homework Assignment #1
Homework Assignment #1

... polymerase II and a collection of basal transcription factors (e.g., TFIID, TFIIB). However, the basal activity of the promoter by itself is very low and is invariably influenced by other specific transcription factors that bind either to the adjacent upstream promoter region (-120 to -30) or to mor ...
No Slide Title
No Slide Title

... Nuclear HAT As are coactivators • Gcn5p is a transcriptional activator of many genes in yeast. It is also a HAT. • PCAF (P300/CBP associated factor) is a HAT and is homologous to yeast Gcn5p. • P300 and CBP are similar proteins that interact with many transcription factors (e.g. CREB, AP1 and MyoD) ...
1) From DNA to protein 2) Gene mutation
1) From DNA to protein 2) Gene mutation

... At the molecular level, mutations or alterations in the nucleotide sequence are in two categories: • A point mutation—results from the gain, loss, or substitution of a single nucleotide • Chromosomal mutations are more extensive—may change the position or cause a DNA segment to be duplicated or lost ...
Microarrays - Computational Bioscience Program
Microarrays - Computational Bioscience Program

... Tzu Lip Phang, Ph.D. Lawrence Hunter, Ph.D. Associate Professor of Bioinformatics ...
Unit 1 Topic Guide Topic Key Content Key Words Healthy diet
Unit 1 Topic Guide Topic Key Content Key Words Healthy diet

...  What is evolution?  What is natural selection?  How does natural selection happen?  How was Lamarck’s theory different from Darwin’s?  Why was Darwin’s theory slow to be accepted? Classification  What is classification?  How are organisms classified?  How can you tell how closely related to ...
What constitutes an `alternative TSS`? Example 1: Alternative TSS at
What constitutes an `alternative TSS`? Example 1: Alternative TSS at

... What if the event involves a terminal exon? 1. Long (‘on’) exon? No – APA! ...
Mendel Vocab
Mendel Vocab

... Each different form of a characteristic, such as stem height or seed color, that an organism can pass on to its offspring through its genes. ...
Genetics Wow!
Genetics Wow!

... •Good communication skills such as listening, empathy and attending to the patient’s agenda will maximise the interaction •Giving a diagnosis of a genetic susceptibility or condition can have the same impact as giving any other ‘bad news’ to an individual •It is important to understand issues of con ...
Genetics Packet 2017
Genetics Packet 2017

... These are some of the basic questions asked by students as we start to talk about cloning. A basic understanding of the different types of cloning is key to making an informed stance on the current issues surrounding cloning. The following are three of the types of cloning being most discussed in th ...
Chapter 18 – The Genetics of Viruses and Bacteria
Chapter 18 – The Genetics of Viruses and Bacteria

... The host provides nucleotides, ribosomes, tRNAs, amino acids, ATP, and other components for making the viral components dictated by viral genes. ...
Biology - Study in Japan
Biology - Study in Japan

... I. Read the following passage and answer the subsequent questions using the answer sheet below. The first organism on the earth is thought to have been a single-cell microorganism such as a bacteria. When life on earth began, the atmospheric composition was very different from today and contained li ...
Sickle cell disease: A multigenic perspective of a single gene disorder
Sickle cell disease: A multigenic perspective of a single gene disorder

... strongest association with Hb F levels was found with SNPs in the 6q 22.3 /23.2 region. Detailed analyses of this region, identified 12 SNPs in the introns of four genes, associated with a 20/30% variation in Hb F [9]. The genes in question were phosphodiesterase 7 (PDE7), microtubule-associated p ...
DISEASE GENETICS DEFICIENCY EPIDEMIOLOGY SYMPTOMS TREATMENT Sickle
DISEASE GENETICS DEFICIENCY EPIDEMIOLOGY SYMPTOMS TREATMENT Sickle

... repeat located in 5’ untranslated region of gene FMR1-normal repeat =60 > 1000 repeats seen in patients (excessive methylation interferes with chromatin condensation or DNA replication or bothtriplet repeats of 60-200 premutation – unstable in mother  child transmission. ...
New Ideas About Far Reaching Effects of an Extra Chromosome 21
New Ideas About Far Reaching Effects of an Extra Chromosome 21

... effective treatments that will improve overall health, cognition and quality of life for children and adults  with Down syndrome. This will build upon and enhance research already ongoing and may also help in  understanding the effects of other trisomies, such as trisomy 18 and trisomy 13.  Personal ...
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NEDD9

Neural precursor cell expressed developmentally down-regulated protein 9 (NEDD-9) is a protein that in humans is encoded by the NEDD9 gene. NEDD-9 is also known as enhancer of filamentation 1 (EF1), CRK-associated substrate-related protein (CAS-L), and Cas scaffolding protein family member 2 (CASS2). An important paralog of this gene is BCAR1.
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