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Convergent evolution of complex regulatory
Convergent evolution of complex regulatory

... HoxA locus [data from (12)]. (C) Interactions established by Hoxa13 (vertical orange bar) in both E12.5 digits (top) and E15.5 genitals (bottom). Most contacts are observed within a 1-Mb regulatory landscape, telomeric to the cluster (red shaded area) in a gene-containing region, matching one TAD. T ...
A Search for Genes Encoding Histidine
A Search for Genes Encoding Histidine

... The phylum Actinobacteria includes agents of socially important diseases (tuberculosis, paratuberculosis, leprosy, diphtheria, etc.), plant pathogens, producers of antibiotics, components of the normal human intestinal microflora, and free-living species suitable for sewage treatment including radia ...
http://sciencecases.lib.buffalo.edu/cs/files/pharmacogenetics.pdf
http://sciencecases.lib.buffalo.edu/cs/files/pharmacogenetics.pdf

... It’s called the children’s ward. For two teenagers who have been recently diagnosed with leukemia, it seems insulting to have their lives hijacked by doctors and nurses with stuffed animals clipped to their stethoscopes. Laura is a forward on her school soccer team and leads the league in scoring. F ...
Toxicity Mechanisms Identification via Gene Set
Toxicity Mechanisms Identification via Gene Set

... approach.1,2 The advances in high-throughput toxicogenomics technologies, which allow for globally concurrent monitoring of cellular responses of numerous transcripts, proteins, or metabolites upon exposure to chemical toxicants, presents promise for achieving this goal.2,3 High-dimensional toxicoge ...
Identification of three MADS‐box genes expressed in sunflower
Identification of three MADS‐box genes expressed in sunflower

... homeotic genes, encoding the A, B and C functions, act alone or in combination to give rise to sepals, petals, stamens and carpels. Genes in the AG group include the C function homeotic genes, involved in stamen, and carpel development. Genes in both the DEF and the GLO groups comprise the B functio ...
Microarray expression data
Microarray expression data

... * the SVM is used then to recognize and classify the genes in the data set to the established groups on the basis of their expression * the SVM can also identify genes in the training set that are outliers or that have been previously assigned to the incorrect class * an application of potentially g ...
Identification of eight novel coagulation factor XIII subunit A
Identification of eight novel coagulation factor XIII subunit A

... frequency 0.005), and two further Tyr167Cys and Arg540Gln variants, represent possible candidates for rare F13A gene polymorphisms since they apparently do not have a significant influence on FXIIIA protein structure. Future in vitro expression studies for these FXIII mutations are required to confi ...
Gametes and Fertilization: Maize as a Model System for
Gametes and Fertilization: Maize as a Model System for

Exam notes for bio250 semester one
Exam notes for bio250 semester one

... hydrogen. The folded protein is held together by hydrophobic interactions, non-covalent bonds and disulfide linkages. The Src protein has 4 different domains for specialized functions. Src signals pathways and it contains regulatory and catalytic domains. Hemoglobin is composed of 4 subunits, 2 alph ...
Fish Evolution LabAnswers
Fish Evolution LabAnswers

... Charles Darwin proposed the revolutionary idea that varieties of forms and species are derived from a common ancestor— “descent with modification.” When a population of similar, related individuals acquires new characteristics over many generations, we refer to that process of modification over time ...
Missing Value Estimation for Gene Expression Profile Data
Missing Value Estimation for Gene Expression Profile Data

... of the observed values over that gene[5] . Case deletion procedures may bias the results if the remaining cases are unrepresentative of the entire sample. Because the same value is used to replace MVs in a given gene, both zero and mean substitutions will reduce the variance of the variable in quest ...
Improved Efficacy of a Gene Optimised Adenovirus
Improved Efficacy of a Gene Optimised Adenovirus

Assembly of additional heterochromatin distinct from centromere
Assembly of additional heterochromatin distinct from centromere

... telomeric repeats placed at both ends of the molecule by I-SceI digestion, a bsr gene driven by the SV40 early promoter (including the enhancer element) on the right side of the alphoid array and a loxP sequence on the left side (Fig. 1A). Next, we obtained three derivative HAC vectors by the Cremed ...
Growth Hormone_________ JESSSSSSSSSSSSSSSSSSSSSSSICA
Growth Hormone_________ JESSSSSSSSSSSSSSSSSSSSSSSICA

... molecular weight of 22,124 daLTONS. The structure includes four helices necessary for functional interaction with the GH receptor. It appears that, in structure, GH is evolutionarily homologous to prolactin and chorionic somatomammotropin. Despite marked structural similarities between growth hormon ...
Retina International Congress 2014 Summary
Retina International Congress 2014 Summary

... with a study of candidate genes and a whole genome of reliable data. Dr Rozet concluded that it was up to a geneticist to determine the most appropriate strategy to find a result in accord with the findings of the molecular biologist but they may not be 100% correct. He emphasised that the provision ...
Body maps on the human genome | SpringerLink
Body maps on the human genome | SpringerLink

... [2], but it seems to have a global landscape, with largescale patterns encompassing all chromosomes together. One key to revealing this structure is chromosome territories, that is, their sites in the cell nucleus. Tissuespecific genes of the adult human body then appear to map somatotopically onto ...
What is systems biology? - McGraw Hill Higher Education
What is systems biology? - McGraw Hill Higher Education

... Formulate a hypothesis-driven query and test through genetic or environmental manipulations Integrate different types of graphical or mathematical data Perform iterative perturbations with a second round of genetic and environmental manipulations Evaluate whether the refined model can predict the be ...
Automatically Generating Gene Summaries from Biomedical Literature
Automatically Generating Gene Summaries from Biomedical Literature

... in the FlyBase report. This paragraph contains good example sentences for each aspect of a gene. A typical paragraph contains information related to gene product, sequence information, genetical interaction, etc. More importantly, verbs such as “encode”, “sequence” and “interact” in the text are ver ...
Osteoclasts
Osteoclasts

... remodeling, have been revealed as essential for the regulation of gene expression by transcription factors (11). In particular, reversibly regulated histone methylation is regarded as the most important storage of epigenetic information that defines cell fate and identity. An essential role for Jumo ...
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Hox-code in Thymus Identity Ana Sofia Salvador Santos
Hox-code in Thymus Identity Ana Sofia Salvador Santos

... evolutionary developmental biology. The transcription factors Homeobox (Hox) genes are responsible for positional identity during development and are ruled out by a spatially collinear of gene expression along the AP-axis of the embryo and by phenotypic suppression by posterior genes. In this study ...
Control of the meiotic cell division program in plants | SpringerLink
Control of the meiotic cell division program in plants | SpringerLink

... WIH peptides are the tetraspanin-type transmembrane protein TORNADO 2 (TRN2) and the leucine-rich repeat protein TRN1 (Lieber et al. 2011). However, WIH-TRN interactions still need to be confirmed, and it is also up to now not clear what the downstream targets of this putative signaling cascade are. ...
ch 13 test-patterns of inheritance
ch 13 test-patterns of inheritance

... -chromosomes are long molecules of DNA wrapped around protein -but only part of this DNA codes for proteins -the other part, noncoding DNA or introns, isn’t translated -about 1.5% of their DNA is translated as proteins -in prokaryotes: -bacteria have a single circular chromosome with little associat ...
Page 1 MEIOSIS AND VARIATION A2.8 QUESTIONSHEET 1
Page 1 MEIOSIS AND VARIATION A2.8 QUESTIONSHEET 1

... (a) A = chromatid; B = spindle fibre; C = centriole; D = centromere; E = chiasma; ...
Mouse models of obesity
Mouse models of obesity

... In humans, agouti is expressed in various tissues, including adipose tissue,[15 and 16] suggesting that it may be involved in the regulation of energy homeostasis. A recent study has found that transgenic mice overexpressing agouti in adipose tissue are significantly heavier than nontransgenic mice. ...
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NEDD9

Neural precursor cell expressed developmentally down-regulated protein 9 (NEDD-9) is a protein that in humans is encoded by the NEDD9 gene. NEDD-9 is also known as enhancer of filamentation 1 (EF1), CRK-associated substrate-related protein (CAS-L), and Cas scaffolding protein family member 2 (CASS2). An important paralog of this gene is BCAR1.
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