Final from 2012
									
... The hemichordate worm is in the same phylum as we are, so might be expected to share some developmental mechanisms. However, in contrast to us, the worm develops a distributed nerve net, with neurons distributed throughout the skin. In some ways this is more like neurogenesis in Drosophila than vert ...
                        	... The hemichordate worm is in the same phylum as we are, so might be expected to share some developmental mechanisms. However, in contrast to us, the worm develops a distributed nerve net, with neurons distributed throughout the skin. In some ways this is more like neurogenesis in Drosophila than vert ...
									Document
									
... must be homozygous dominant, “BB”, a blond Prince Charmin must be homozygous recessive, “bb”. B ...
                        	... must be homozygous dominant, “BB”, a blond Prince Charmin must be homozygous recessive, “bb”. B ...
									Open Research Online Stacked regression ensemble for cancer
									
... which used SVM with different kemels including Linear, Polynomial and Radial Basis Function (RBF) and Generalized Regression Neural Network (GRNN) as base classifiers. The motivation to use SVM- and GRNN was their promising results in a variety of biological classification tasks, including gene expr ...
                        	... which used SVM with different kemels including Linear, Polynomial and Radial Basis Function (RBF) and Generalized Regression Neural Network (GRNN) as base classifiers. The motivation to use SVM- and GRNN was their promising results in a variety of biological classification tasks, including gene expr ...
									Chromatin dynamics during cellular differentiation in the female
									
... important rewiring of the transcriptional program. The surrounding somatic cells play a central role in either promoting or restricting the developmental competence of the SMC and gametophyte (for comprehensive reviews, see Feng et al., 2013; Schmidt et al., 2015). The molecular pathways involved in ...
                        	... important rewiring of the transcriptional program. The surrounding somatic cells play a central role in either promoting or restricting the developmental competence of the SMC and gametophyte (for comprehensive reviews, see Feng et al., 2013; Schmidt et al., 2015). The molecular pathways involved in ...
									Hemophilia B (F9) Sequencing and Deletion/Duplication
									
... • Diagnosis of hemophilia B is established by deficiency of factor IX coagulation activity o Lower activity levels correspond with earlier age of diagnosis and higher frequency of bleeding episodes • First-line testing in most individuals is not molecular o Molecular genetic testing may be helpful i ...
                        	... • Diagnosis of hemophilia B is established by deficiency of factor IX coagulation activity o Lower activity levels correspond with earlier age of diagnosis and higher frequency of bleeding episodes • First-line testing in most individuals is not molecular o Molecular genetic testing may be helpful i ...
									The nuclear envelope in genome organization, expression and
									
... in larger eukaryotes such as rats and flies18,49. This suggests that pools of NPC proteins may have different functions depending on their subnuclear localization. Indeed, it was recently proposed that nucleoplasmic NPC components can activate the expression of internally localized genes, whereas DN ...
                        	... in larger eukaryotes such as rats and flies18,49. This suggests that pools of NPC proteins may have different functions depending on their subnuclear localization. Indeed, it was recently proposed that nucleoplasmic NPC components can activate the expression of internally localized genes, whereas DN ...
									Interpreting the prevalence of regulatory Snps in cancers and protein coding SNPs among non-cancer diseases using GWAS Association Studies
									
... mutation on a gene that explains all the disease cases, however, complex diseases do not associate strongly with a single gene mutation, and rather they are caused by variant forms of several genes which can be the direct result of several single nucleotide polymorphisms targeting these genes. Among ...
                        	... mutation on a gene that explains all the disease cases, however, complex diseases do not associate strongly with a single gene mutation, and rather they are caused by variant forms of several genes which can be the direct result of several single nucleotide polymorphisms targeting these genes. Among ...
									(FISH) or Immunohistochemistry (IHC)
									
... DESCRIPTION: The human epidermal growth factor receptor 2 (HER-2/neu) oncogene is found in high concentrations on the cell surfaces of various cancers. Each cell should have only two copies of the HER-2/neu gene. If it has more than two copies, the cell produces too much of the HER-2/protein. Excess ...
                        	... DESCRIPTION: The human epidermal growth factor receptor 2 (HER-2/neu) oncogene is found in high concentrations on the cell surfaces of various cancers. Each cell should have only two copies of the HER-2/neu gene. If it has more than two copies, the cell produces too much of the HER-2/protein. Excess ...
									NAR Breakthrough Article Identification of a mismatch
									
... have been performed, and these functions are basically conserved from prokaryotes to eukaryotes (1–8). In spite of our increasing knowledge about DNA repair, the pathways and proteins involved in DNA repair in Archaea, the third domain of life, are still poorly understood (9–12). Homology searches o ...
                        	... have been performed, and these functions are basically conserved from prokaryotes to eukaryotes (1–8). In spite of our increasing knowledge about DNA repair, the pathways and proteins involved in DNA repair in Archaea, the third domain of life, are still poorly understood (9–12). Homology searches o ...
									Genoplante 2007, ANR-07-GPLA-002
									
... In the Buchnera symbiosis of aphids, plasmidic genes for leucine biosynthesis were shown for the first time to have a high and dynamically regulated transcriptional response, scaling biosynthesis to the external leucine excess or depletion, showing that the adaptive regulation of gene expression is ...
                        	... In the Buchnera symbiosis of aphids, plasmidic genes for leucine biosynthesis were shown for the first time to have a high and dynamically regulated transcriptional response, scaling biosynthesis to the external leucine excess or depletion, showing that the adaptive regulation of gene expression is ...
									CHAPTER 13 MEIOSIS AND SEXUAL LIFE CYCLES
									
... Let’s discuss the role of meiosis in the human life cycle.  The human life cycle begins when a haploid sperm cell fuses with a haploid ovum.  These cells fuse (syngamy), resulting in fertilization.  The fertilized egg (zygote) is diploid because it contains two haploid sets of chromosomes bearin ...
                        	... Let’s discuss the role of meiosis in the human life cycle.  The human life cycle begins when a haploid sperm cell fuses with a haploid ovum.  These cells fuse (syngamy), resulting in fertilization.  The fertilized egg (zygote) is diploid because it contains two haploid sets of chromosomes bearin ...
									Test Information Sheet
									
... Combined 17α-hydroxylase/17,20-lyase deficiency is a disorder of steroidogenesis associated with a broad range of clinical presentations. The steroid abnormalities result in a rare form of congenital adrenal hyperplasia (CAH) that accounts for about 1% of cases of CAH overall. The 17α-hydroxylase de ...
                        	... Combined 17α-hydroxylase/17,20-lyase deficiency is a disorder of steroidogenesis associated with a broad range of clinical presentations. The steroid abnormalities result in a rare form of congenital adrenal hyperplasia (CAH) that accounts for about 1% of cases of CAH overall. The 17α-hydroxylase de ...
									chapter 13 meiosis and sexual life cycles
									
... Let’s discuss the role of meiosis in the human life cycle.  The human life cycle begins when a haploid sperm cell fuses with a haploid ovum.  These cells fuse (syngamy), resulting in fertilization.  The fertilized egg (zygote) is diploid because it contains two haploid sets of chromosomes bearin ...
                        	... Let’s discuss the role of meiosis in the human life cycle.  The human life cycle begins when a haploid sperm cell fuses with a haploid ovum.  These cells fuse (syngamy), resulting in fertilization.  The fertilized egg (zygote) is diploid because it contains two haploid sets of chromosomes bearin ...
									CP Case Conference - the UCLA Department of Pathology
									
...  Anti-Jsb is usually seen in black patients (Jsb antigen is negative in 20% of blacks and <1% of whites)  It is usually seen in sickle cell disease patient with multiple alloantibodies  Need to search Red Cross national vare blood type database to find compatible RBCs and usually frozen units  D ...
                        	...  Anti-Jsb is usually seen in black patients (Jsb antigen is negative in 20% of blacks and <1% of whites)  It is usually seen in sickle cell disease patient with multiple alloantibodies  Need to search Red Cross national vare blood type database to find compatible RBCs and usually frozen units  D ...
									Interaction of Sesbania Mosaic Virus Movement Protein
									
... tested by an enzyme-linked immunosorbent based assay (ELISA), as described previously with minor modifications [29,30,31,32]. The ELISA plate (F8 Nunc Maxisorp loose,Nunc, Kamstrupvej 90, Postbox 280, DK-4000, Roskilde, Denmark) wells were coated with 5.0 mg of purified VPg or P10 (100 ml /well) for ...
                        	... tested by an enzyme-linked immunosorbent based assay (ELISA), as described previously with minor modifications [29,30,31,32]. The ELISA plate (F8 Nunc Maxisorp loose,Nunc, Kamstrupvej 90, Postbox 280, DK-4000, Roskilde, Denmark) wells were coated with 5.0 mg of purified VPg or P10 (100 ml /well) for ...
									Expression of the Floral B-function Gene SLM2 in Female Flowers of
									
... inhibit male organogenesis. Secondly, a downstream target gene activated by SLM2 could link to the Y chromosome. The lack of downstream genes results in the failure of male organogenesis in infected females. Law et al. (2002) induced the maturation of anthers in female plants with the use of silver ...
                        	... inhibit male organogenesis. Secondly, a downstream target gene activated by SLM2 could link to the Y chromosome. The lack of downstream genes results in the failure of male organogenesis in infected females. Law et al. (2002) induced the maturation of anthers in female plants with the use of silver ...
... orthologs in other species be referred to only by their NCU numbers until such time as N. crassa experimental data provide the basis for a name. Therefore, we consider how to provide names and symbols for previously undescribed N. crassa genes that reflect the emerging practice arising from in silic ...
									Candidate gene prioritization with Endeavour
									
... with many human complex traits and Mendelian disorders remaining unexplained despite the availability of huge amounts of genome-scale data. In this situation, computational biology aims at reducing this gap by proposing in silico methods that analyze these data to derive hypotheses that can be valid ...
                        	... with many human complex traits and Mendelian disorders remaining unexplained despite the availability of huge amounts of genome-scale data. In this situation, computational biology aims at reducing this gap by proposing in silico methods that analyze these data to derive hypotheses that can be valid ...
									Profile of Edward M. De Robertis - Howard Hughes Medical Institute
									
... Hamburger, as well as one by embryologist Hans Spemann (7) who taught Hamburger, sparked discussion in the club about the possibility of isolating genes involved in embryonic induction. In 1924, Spemann and a colleague had shown that a region of the amphibian embryo was able to induce the formation ...
                        	... Hamburger, as well as one by embryologist Hans Spemann (7) who taught Hamburger, sparked discussion in the club about the possibility of isolating genes involved in embryonic induction. In 1924, Spemann and a colleague had shown that a region of the amphibian embryo was able to induce the formation ...
									The role of testis-specific gene expression in sex
									
... compensation occurs in the male germline of Anopheles, to help resolve which mechanisms contribution to this trend. Since Y chromosome degeneration appears to have evolved rapidly in Anopheles after its divergence from Aedes, further study is likely to yield important insight into how these processe ...
                        	... compensation occurs in the male germline of Anopheles, to help resolve which mechanisms contribution to this trend. Since Y chromosome degeneration appears to have evolved rapidly in Anopheles after its divergence from Aedes, further study is likely to yield important insight into how these processe ...
									BASIC Role of Genes – 07/02/2012
									
... A deletion of a T base results in a shorter than normal protein An extra base (A) causes altered expression of the protein In this case two base pairs are missing ...
                        	... A deletion of a T base results in a shorter than normal protein An extra base (A) causes altered expression of the protein In this case two base pairs are missing ...
									Gregor Mendel used pea plants to study
									
... Suppose the homologous chromosomes that make up a tetrad fail to separate during anaphase I of meiosis. Predict the results of this event. ...
                        	... Suppose the homologous chromosomes that make up a tetrad fail to separate during anaphase I of meiosis. Predict the results of this event. ...