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chapter 13 meiosis and sexual life cycles
chapter 13 meiosis and sexual life cycles

... The number of combinations possible when chromosomes assort independently into gametes is 2n, where n is the haploid number of the organism.  If n = 3, there are 23 = 8 possible combinations.  For humans with n = 23, there are 223, or more than 8 million possible combinations of chromosomes. ...
Scale-free networks - Chair of Computational Biology
Scale-free networks - Chair of Computational Biology

... connectivity of the respective domains. Extensive shuffling of domains to increase combinatorial diversity might provide protein sets which are sufficient to preserve cellular procedures without dramatically expanding the absolute size of the protein complement.  greater proteome complexity of high ...
Recombinant_Project_Proposal_revised_(really)
Recombinant_Project_Proposal_revised_(really)

... of Gram negative, rod shaped bacteria ...
PDF+Links
PDF+Links

... (Selkoe, 1998). According to the “amyloid cascade hypothesis”, abnormalities of APP metabolism with subsequent b-amyloid (Ab) generation play a central role in the pathogenesis of AD (Hardy & Higgins, 1992). APP is processed by three proteases, named a-, b-, and g-secretases. A series of endoproteol ...
Summary/Reflection of Dan Freedman`s article, Science Education
Summary/Reflection of Dan Freedman`s article, Science Education

... Note that each pole will form a new nucleus that will have half the number of chromosomes, but each chromosome will contain two chromatids. b. Since daughter nuclei will have half the number of chromosomes, cells that eventually form will be haploid. 5. Beginning in telophase I, the cells of many sp ...
4 points: Chemistry, Science, Cells
4 points: Chemistry, Science, Cells

... process called where material moves from a LOW to HIGH concentration? ...
Hemoglobin
Hemoglobin

... Formation of a protrusion on the b-globin that fit into a complementary site on the a chain of another hemoglobin molecule in the cell. In low oxygen tension, deoxy HB S polymerize inside the red blood cell leading to stiffening & distorting of the cell ending in production of rigid misshapen RBCs. ...
Osteogenesis Imperfecta
Osteogenesis Imperfecta

... sufficient for completely normal bone structure. However, mutations that result in a mutant proα1 protein that is synthesized, but not functional, cause much more severe cases of osteogenesis (types II, III, and IV). In this case, 50% of proα1 protein will be abnormal, but because bone collagen is a ...
Summary - WordPress.com
Summary - WordPress.com

... Parkinson’s disease is caused by the loss of dopaminergic neurons within the substantia nigra of the brain linked to declines in mitochondrial function. Protection of mitochondrial integrity is ensured by the PINK1-Parkin pathway which is present in both, Drosophila and human. This pathway contains ...
Is HP1 an RNA detector that functions both in repression and
Is HP1 an RNA detector that functions both in repression and

... The reverse was observed 7 h after heat shock. The authors speculate that the inverse effects of each class of mutation at the different time points are a result of an autoregulatory feedback mechanism that is known to respond to heat shock protein levels in heat shock recovery. It is conceivable th ...
6.1 Chromosomes and Meiosis
6.1 Chromosomes and Meiosis

... 2. Do you think that Y chromosomes contain genes that are critical for an organism’s survival? Explain. • No, a Y chromosome is not necessary for survival. Females do not have a Y chromosome, and they are able to survive. ...
Thrombocytopenia
Thrombocytopenia

... – Regulates expression of many hematopoietic-specific genes • Inversely regulates MYL9 and MYH10 • Directly regulates MYH9 • Thus suggests megakaryopoiesis may be effected in part by deregulation of myosin IIA and IIb  defective proplatelet formation ...
Screening of a Specific Point Mutation in Tumor Suppressor p53
Screening of a Specific Point Mutation in Tumor Suppressor p53

... This result is quite different from the report on Chinese and South African patients that showed the point mutations at the same site with the frequency of 50% in hepatocellular carcinoma sample. Even though this particular point mutation was not found in Korean samples, there might be mutations at ...
Virus-mediated reprogramming of gene expression in plants John A
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... gene silencing [3]. This is an important feature for genomics applications, which makes it possible to obtain a gene-knockout phenotype even without having access to the entire gene sequence. It should also be possible to simultaneously silence multiple genes from a single viral vector by expressing ...
Transgenic and Gene Targeting Core
Transgenic and Gene Targeting Core

... standardized form and b) Investigator’s applicable IACUC protocol (“Experimental Protocol”) which provides for the utilization of the transgenic animals following their development by the TGTC (UC Denver CCMhoused animals only). Investigator hereby represents and warrants that the DNA construct(s) o ...
SUNLIBB Work Packages, Aims and Achievements
SUNLIBB Work Packages, Aims and Achievements

... Supporting activities included, among others; preparation of two Policy Briefs for the project’s website (www.sunlibb.eu); an exchange visit to Brazil for dialogue with partners in the sister CeProBio Project at the University of Sao Paulo; interviews with stakeholders on bilateral (EU-Brazil), as w ...
Type-2 fuzzy Approach for Disease-Associated Gene Identification on Microarrays  Yan-Fei Wang
Type-2 fuzzy Approach for Disease-Associated Gene Identification on Microarrays Yan-Fei Wang

... set theory into the research of disease-associated gene identification. Type-2 fuzzy sets can control the uncertainty information more effectively than conventional type-1 fuzzy sets because the membership functions of type-2 fuzzy sets are three-dimensional. It is the new third dimension of type-2 ...
Lecture 5
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... If chromosomes misalign, recombination leads to gain in genes on one chromosome and loss of genes on the other. Tandem arrays of genes ...
pGLO GFP purification manual 4006099
pGLO GFP purification manual 4006099

... Examine your two transformation plates under the ultraviolet (UV) lamp. On the LB/amp plate pick out a single colony of bacteria that is well separated from all the other colonies on the plate. Use a magic marker to circle it on the bottom of the plate. Do the same for a single green colony on the L ...
Misexpression of genes in Drosophila melanogaster
Misexpression of genes in Drosophila melanogaster

... A: The coding region – This is the part of the gene that contains the codons that are transcribed into mRNA and eventually translated into protein. This sounds familiar, right? B: The regulatory region – This is the part of the gene that contains the “instructions” that indicate exactly where (which ...
How many genes in Arabidopsis come from cyanobacteria? An
How many genes in Arabidopsis come from cyanobacteria? An

... corresponding Arabidopsis protein and BLAST table protein was discarded. Using the fall-off-point criterion, we identified 410 Arabidopsis proteins that have a ‘good’ Synechocystis homologue, thus warranting further investigation through phylogenetic analysis. In terms of gene families, these 410 en ...
Ectopic expression of the PttKN1 gene in Cardamine hirsuta
Ectopic expression of the PttKN1 gene in Cardamine hirsuta

... tein were: molecular weight=42.45 kDa; theoretical isoelectric point (pI)=6.03; estimated half-life=30 h; instability index=51.22, and it was classified as an unstable protein. The protein had no transmembrane and signal peptide, and was a soluble protein (SignalP, TMHMM and ProtScale programs). The ...
Document
Document

... • Usually aneuploids are not viable or severely affected due to changes in gene balance. In a euploid the ratio between genes is 1:1 **even in aberrant euploidy, -whereas in aneuploid this balance is variable ...
2009 - Wings Over Wall Street
2009 - Wings Over Wall Street

... Our scientists, for example, first explained one of the main reasons for cell death in ALS. That find formed the basis for a decade of drug discovery leading to Riluzole, the only FDA-approved drug for ALS. Scientific work at Packard is not about throwing darts at a board, hoping for a bulls-eye, bu ...
Prep1.1 has essential genetic functions in hindbrain development
Prep1.1 has essential genetic functions in hindbrain development

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NEDD9

Neural precursor cell expressed developmentally down-regulated protein 9 (NEDD-9) is a protein that in humans is encoded by the NEDD9 gene. NEDD-9 is also known as enhancer of filamentation 1 (EF1), CRK-associated substrate-related protein (CAS-L), and Cas scaffolding protein family member 2 (CASS2). An important paralog of this gene is BCAR1.
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