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Glucocorticoid-remediable aldosteronism
Glucocorticoid-remediable aldosteronism

... in GRA, they have been found in rodents to have only weak mineralocorticoid activity [8]. However, it is possible that these hybrid compounds possesssignificant mineralocorticoid activity in humans. The molecular basis of GRA was discovered by applying a candidategene approachin a pedigree where aff ...
Keystone2011poster
Keystone2011poster

... The sequencing and phylogenetic analysis of rRNA molecules demonstrated that all organisms could be placed on a single tree of life. Highly conserved, homologous 16S rRNA genes' presence in all organismal lineages makes them the only universal marker that has been adopted by biologist. Unfortunately ...
Pleurochrysome: A Web Database of
Pleurochrysome: A Web Database of

... (nr) using each UNIGENE sequence as a query. Applying 1E10 as a threshold e-value, 3,215 UNIGENEs were annotated with at least one similar sequence in the databases. Conserved domain information and Gene Ontology (GO) information were retrieved by InterProScan. Conserved domains were detected in 5,7 ...
University of Groningen Regulation of hepatobiliary transport
University of Groningen Regulation of hepatobiliary transport

... mobility shift assays and luciferase studies in vitro and was shown to be functional and to bind the PPARα/RXR complex. We propose that MDR3 regulation occurs at the transcriptional level by binding of PPARα/RXR to a DR1 response element located at -4926 to -4913 in the promoter region of the MDR3 g ...
Gene Section PAX8 (paired box 8) Atlas of Genetics and Cytogenetics
Gene Section PAX8 (paired box 8) Atlas of Genetics and Cytogenetics

... In fact, PPFP oncogenic effects could relate to constitutive overexpression of the full length PPARgamma1 domain, interference with wild-type PPARgamma1 or PAX8 function, novel intrinsic properties of PPFP, or a combination of the above. PPARgamma1 is thought to be the principal target of a class of ...
Study of the Effects of High-Energy Proton Beams
Study of the Effects of High-Energy Proton Beams

... Escherichia coli (E. coli) is an important biological model to obtain metabolic and genetic information for studying toxicity and antimicrobial activity of pathogenic bacteria [6]. Most studies on the effect of ionizing radiation on E. coli have done with gamma irradiation, UV light and X-ray radiat ...
Vectors - Rajshahi University
Vectors - Rajshahi University

... advantage of the phage vector is its high transformation efficiency, about 1000 times more efficient than the plasmid vector. ...
Plant Molecular Biology
Plant Molecular Biology

... host plants. The inducing compounds found in these exudates have been identified as flavones, flavanones or closely related compounds [24, 25, 9, 37, 40]. A strongly conserved regulatory domain, designated the nodbox, is present upstream for all inducible nod operons and appears to be essential for ...
DNA Recombination Mechanisms
DNA Recombination Mechanisms

... Recombination generates genetic diversity ...
PSL302Y Classic Endocrine Glands
PSL302Y Classic Endocrine Glands

... factor into a specialized cardiovascular system, where they travel to the anterior pituitary where they can inhibit or stimulate other the release of other hormones. Vasopressin travels through the blood stream and binds to its receptor on the membrane of the collecting duct cells, which activates a ...
Cystic fibrosis - patient information
Cystic fibrosis - patient information

... CF. With a one in four chance, the odds are three to one in their favour. Some choose not to have any (more) children. Many choose to have prenatal testing that will tell them if the baby has inherited two cystic fibrosis genes and will therefore have cystic fibrosis. There are choices in prenatal t ...
UP-CPMT - 2007 Paper-1
UP-CPMT - 2007 Paper-1

... 3) bile matrix 4) all of them 29. Which of the following is not the character of Taenia solium? 1) Apolysis 2) Proglottid 3) Metamerism 4) Strobila 30. In housefly pseudotracheae is found in 1) haustellum 2) rostrum 3) labellum 4) none of these 31. Process of vernalization can be induced by 1) cytok ...
Slide 1
Slide 1

... Hartikka et al. (2004) reported: ...
PCDH19-related Infantile Epileptic Encephalopathy - HAL
PCDH19-related Infantile Epileptic Encephalopathy - HAL

... development and shows a unique expression profile among protocadherins. In particular, protocadherin 19 is highly expressed in the developing brain, including the subventricular zone, the intermediate zone, the subplate, specific layers (layers II, IV, V and VI) of the cerebral cortex, the hippocam ...
MOLLECULAR BIOLOGY COURSE
MOLLECULAR BIOLOGY COURSE

... genes. The rest of the genes are repressed, or turned off. The process of turning genes on and off is known as gene ...
Document
Document

... this regulation can cause human disease (10). - CDKN1C and IGF2 are both expressed from the same chromosomal region on chromosome 11. They are imprinted, with opposing parent of origin expression. IGF2 is a growth factor, while CDKN1C is a cell cycle inhibitor. Imprinting of each regulates gene dosa ...
Lecture: “Gene interactions. Realization of genetic
Lecture: “Gene interactions. Realization of genetic

... In the hypothetical pathway above, molecule A is converted into molecule B by enzyme 1 and molecule B is then processed to become molecule C by enzyme 2. If either enzyme 1 or enzyme 2 is defective, molecule C cannot be manufactured, producing a mutant phenotype. Defects in enzyme 1 or 2 may show up ...
GhMYB25-like: a key regulator of early cotton fiber development.
GhMYB25-like: a key regulator of early cotton fiber development.

... GhMYB25 protein and then to the Antirrhinum majus MIXTA (AmMIXTA) and the MIXTA-related transcription factors MIXTA-like 1, 2 and 3 (AmMYBML1, 2 and 3), Petunia hybrida PhMYB1 and Arabidopsis AtMYB16 (Supplementary Figure S1). Phylogenetic analysis showed that GhMYB25, GhMYB25-like and two additiona ...
how function during Drosophila metamorphosis
how function during Drosophila metamorphosis

... eversion and leg extension, suggesting that how plays a role in interactions between imaginal epithelium, peripodial epithelium, and larval epidermal cells. The pleiotropic function of how may indicate that the related genes gld-1 and qk1 in worms and mice are more pleiotropic than suspected, and th ...
A highly fertile fluffy allele, fl^Y, which produces macroconidia. pg
A highly fertile fluffy allele, fl^Y, which produces macroconidia. pg

... Haploidization analysis located the gene for resistance to chromosome V; there were 10 resistant fac^+ and 20 sensitive fac^- haploids, with markers on all other chromosomes segregating independently. Colonies of HU-R2, 3 and 4 had a linear growth rate on CM less than that of wild type, and a modifi ...
Open Access
Open Access

... was recovered from the EMS treated wild-type background A. alpina Pajares (Paj) [42]. The other mutant was found in a mutagenized A. alpina (Paj) background carrying the pep1-1 mutation [42,47,48]. In the A. alpina (pep1-1) background the TTG1 gene contained a mutation that would lead to a T to M ex ...
PART II Introducció 53
PART II Introducció 53

... amb increments en bloc del nombre de gens al genoma. La presència de regions de paralogia al genoma humà és un reflexe d’aquest augment (Lundin et al., 2003). Un exemple descrit de grup paràleg està constituït per regions dels cromosomes 1, 6p, 9, 15 i 19p humans (Figura 5) (Lundin et al., 2003). En ...
FEATURE SELECTION = GENE SELECTION
FEATURE SELECTION = GENE SELECTION

... been developed in the machine learning and data mining fields, specific applications in bioinformatics have led to a wealth of newly proposed techniques. • The high dimensional nature of many modelling tasks in bioinformatics, going from sequence analysis over microarray analysis to spectral analyse ...
Immunogenetics
Immunogenetics

... The two DNA recombinational events required to assemble a functional heavy chain V region gene, are governed by the 7-9 and the 12-23 rules. Explain.  Discuss four mechanisms that contribute to antibody diversity.  Describe the differential splicing of RNA that progresses from membrane bound IgM ...
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NEDD9

Neural precursor cell expressed developmentally down-regulated protein 9 (NEDD-9) is a protein that in humans is encoded by the NEDD9 gene. NEDD-9 is also known as enhancer of filamentation 1 (EF1), CRK-associated substrate-related protein (CAS-L), and Cas scaffolding protein family member 2 (CASS2). An important paralog of this gene is BCAR1.
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