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Topic 14: Protein Synthesis
Topic 14: Protein Synthesis

... specified by the gene sequence. How is this used to make protein? fig. 17.13- transfer RNA (tRNA); specialized RNA molecules that literally are involved in transferring the appropriate amino acid to the growing polypeptide chain 1. roughly 80 nucleotides long 2. at the 3’ end in a site where a parti ...
Metabolism—chapter 4
Metabolism—chapter 4

... Metabolic processes include the sum total of ALL chemical reactions that occur in a body. There are two kinds: Catabolism (breaking down of large molecules) and Anabolism (building up smaller molecules). Basically every time you eat something you digest it into small pieces that are they ‘recycled’ ...
Dna, Protein Synthesis, and gene expression
Dna, Protein Synthesis, and gene expression

... 500-4500 bases; depending on size of gene Every three bases are called a ___________ 75-80 bases that bind in cloverleaf shape One end bonds to a specific amino acid One end has a three base code called the _________ ...
Notes
Notes

... DNA code to the ribosome to direct the making of protein; occurs in nucleus • Translation - the process of building proteins, the sequence of bases of mRNA is “translated” into a sequence of amino acids; occurs in ribosome ...
Chapter 15
Chapter 15

... expect high or low levels of error in transcription as compared with DNA replication? Why do you think it is more important for DNA polymerase than for RNA polymerase to proofread? (Page 283) Answer: One would expect higher amounts of error in transcription over DNA replication. Proofreading is impo ...
DKN_5-8 TYPE
DKN_5-8 TYPE

... Converting DNA to RNA is called TRANSCRIPTION RNA polymerase makes messenger RNA (mRNA) -message can encode: protein, tRNA, rRNA, non-coding RNA DRAW CARTOON: 5 subunits  and  a  single  regulatory  subunit  known  as  sigma   (σ).    Different  sigma  factors  help  RN ...
Central Dogma Mini-Book Instructions
Central Dogma Mini-Book Instructions

... out. To solve this problem, copies of the DNA are made in a form called mRNA. The process of making mRNA from DNA is called transcription. After transcription, the mRNA copies leave the nucleus to be in the part of the cell outside the nucleus, otherwise known as the cytoplasm. mRNA can’t build a ce ...
Translation - Fog.ccsf.edu
Translation - Fog.ccsf.edu

... Each codon specifies either an amino acid or stop signal to translation There are only 20 amino acids and there are 64 possible codons The genetic code is degenerate - i.e. there are "synonyms" (multiple codons) for some amino acids Three codons (UAG, UGA, and UAA) encode translation "stop" signals ...
Assignment
Assignment

... In the following assignment you will characterize a mutation that is associated with a deficiency in the human immune system’s response to bacterial infection. In this hypothetical situation, a patient has an unexplained immune deficiency that causes them to be susceptible to typhoid fever (Salmonel ...
word - marric.us
word - marric.us

... What does this experiment indicate? a) The amino acid phenylalanine is composed of uracil. b) UUU codes for the amino acid phenylalanine. c) Protein synthesis malfunctions in test tubes. d) Most proteins contain only one type of amino acid. ...
Sample
Sample

... 26) Why is mRNA a good intermediate for translation? Answer: mRNA is a good intermediate because it must leave the nucleus and go to the cytoplasm to direct translation. DNA is the genetic code and cannot leave the nucleus and risk degradation. So, mRNA can carry the DNA information to the cytoplas ...
Powerpoint file
Powerpoint file

... are commonly designated by their “S values,” which refer to their rate of sedimentation in an ultracentrifuge. Despite the differences in the number and size of their rRNA and protein components, both prokaryotic and eukaryotic ribosomes have nearly the same structure and they function similarly. ...
Chapter 17- Transcription and Translation
Chapter 17- Transcription and Translation

... C) What is an activator protein (specific transcription factor)? D) What region of the DNA do the activator proteins bind to? E) How is the binding of transcription factors and activator proteins impacted by the how tightly DNA is bound to histones (level of DNA packing)? ...
How Genes Work
How Genes Work

... Its complex unwinds DNA It copies bases using complimentary base pairing (U v.s. T) Moves down one strand Stops at terminator ...
Worksheet - DNA Code
Worksheet - DNA Code

... Name: ...
lec3
lec3

... Splicing is important (1) splicing allows variations of a gene and therefore gene product to be made (2) it has been suggested that exons correspond to functional motifs in proteins and thus the presence of genes that require slicing allows for evolutionary tinkering (3) many viruses have spliced mR ...
DNA RNA protein DNA REPLICATION
DNA RNA protein DNA REPLICATION

... Alternative splicing contributes to protein diversity − a single gene transcript (RNA) can have thousands of different splicing patterns, and will therefore code for thousands of different proteins: a diverse proteome is generated from a relatively limited genome. ! Splicing is important in genetic ...
Exporter la page en pdf
Exporter la page en pdf

... Factors such as warm ischemia and time at room temperature before tissue treatment may influence the results of mRNA expression analyses on tissue specimens obtained during surgery. We evaluated the effect of these factors on RNA integrity and mRNA expression levels by incubating freshly obtained mous ...
1) Where does glycolysis occur in the cell
1) Where does glycolysis occur in the cell

... 3) In a cell, most of the FADH2 production occurs ___________. a) on the surface of a ribosome. b) inside the nucleus. c) in the matrix of a mitochondrion. d) between the double membranes of a mitochondrion e) in the cytoplasm ...
Protein Synthesis
Protein Synthesis

... 2. RNA a. mRNA = messenger RNA ™ makes & takes copy of DNA to cytoplasm b. tRNA = transfer RNA ™Matches w/ mRNA on ribosome ™Carries AA to add to protein chain ?s 1-7 ...
Chapter 21 (part 1) - Nevada Agricultural Experiment
Chapter 21 (part 1) - Nevada Agricultural Experiment

... enzyme is a multimeric protein a2,b, b’, w • The b’ subunit is involved in DNA binding • The b subunit contains the polymerase active site • The a subunit acts as scaffold on which the other subunits assemble. • Also requires s-factor for initiation –forms holo enzyme complex ...
Genetics - StudyWise
Genetics - StudyWise

... Pieces of DNA which have a sequence where the same base is repeated many times are called ‘slippery’. When ‘slippery’ DNA is copied during replications, errors may occur in copying. Individual bases may be copied more than once. This may give rise to differences in the protein which is produced by t ...
Molecular Biology
Molecular Biology

... • Many enzymes contain more than one polypeptide chain and each polypeptide is usually encoded in one gene • These observations have lead to the one gene one polypeptide hypothesis: Most genes contain the information for making one polypeptide ...
Airgas template
Airgas template

... ___________________ is the type of RNA that functions to deliver the activated form of amino acids to protein molecules in the ribosomes. ...
10DNAtoProt
10DNAtoProt

... 2. Transcription is terminated when the RNA polymerase encounters a poly-U sequence. 3. Translation ends when a ‘release factor’ protein binds to a stop codon. 4. Initiation of translation in prokaryotes involves binding of the sigma factor to a promoter. 5. Only rRNAs are polyadenylated. 6. Because ...
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Messenger RNA



Messenger RNA (mRNA) is a large family of RNA molecules that convey genetic information from DNA to the ribosome, where they specify the amino acid sequence of the protein products of gene expression. Following transcription of primary transcript mRNA (known as pre-mRNA) by RNA polymerase, processed, mature mRNA is translated into a polymer of amino acids: a protein, as summarized in the central dogma of molecular biology.As in DNA, mRNA genetic information is in the sequence of nucleotides, which are arranged into codons consisting of three bases each. Each codon encodes for a specific amino acid, except the stop codons, which terminate protein synthesis. This process of translation of codons into amino acids requires two other types of RNA: Transfer RNA (tRNA), that mediates recognition of the codon and provides the corresponding amino acid, and ribosomal RNA (rRNA), that is the central component of the ribosome's protein-manufacturing machinery.The existence of mRNA was first suggested by Jacques Monod and François Jacob, and subsequently discovered by Jacob, Sydney Brenner and Matthew Meselson at the California Institute of Technology in 1961.
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