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1st
1st

... DNA polymerase makes about 1 mistake per 105 bp. DNA polymerase has a “proof-reading” activity to correct its own mistakes (99%). After DNA replication there is a “mismatch repair” system to correct remaining mistakes (99.9%). This leaves an overall error rate of about 1 base in 1010. ...
Genes and Genetic Disease
Genes and Genetic Disease

... Principle of segregation– homologous genes separate, reproductive cells carry only one gene (meiosis) Principle of independent assortment – hereditary transmission of one gene does not affect the transmission of another. ...
Gene Section PDCD6 (programmed cell death 6) Atlas of Genetics and Cytogenetics
Gene Section PDCD6 (programmed cell death 6) Atlas of Genetics and Cytogenetics

... interact with PDCD6 in a calcium dependent fashion have been found. Most prominent are AIP1/Alix, an adaptor protein involved in apoptosis, endocytosis, adhesion and cytokinesis as well as TSG101, a tumor suppressor gene product, which is a component of the ESRT-1 (endosomal sorting complex required ...
DNA Webquest - sciencewithskinner
DNA Webquest - sciencewithskinner

... 3. How many nucleotides might be in a "real" mRNA molecule? _____________ 4. The "m" in mRNA stands for: ______________________________________ 5. Once constructed, the mRNA leaves the cell's nucleus and travels to the: a) cytoplasm b) nucleolus c) nucleus d) ribosomes 6. Find the single strand of m ...
Microbial Genetics Chromosomes Genes Related to Obesity in the
Microbial Genetics Chromosomes Genes Related to Obesity in the

... • micro RNAs, anti‐sense RNAs,  riboswitches, small interfering  RNAs ...
DNA Replication and recombination
DNA Replication and recombination

... III. History of solving the structure of DNA ...
Biology Review
Biology Review

... Ecology – study of the interaction of organisms and their environment Organism – one member of a species Population- every member of a single species in an area Community- all LIVING things in an area (BIOTA) Ecosystem –all living and non living components in an area (BIOTA and ABIOTA) Biosphere – ...
Transcription
Transcription

... It is like DNA replication in that a DNA strand is used to synthesize a strand of mRNA. Only one strand of DNA is copied. A single gene may be transcribed thousands of times. After transcription, the DNA strands rejoin. Steps involved in transcription RNA polymerase recognizes a specific base sequen ...
- PhagesDB
- PhagesDB

... Interestingly, both gp15 & gp17 give good hits as encoding a major tail subunit protein. We not that the closely related AM cluster Circum genome homologs have been annotated as capsid genes. We feel these two related homolog are in fact MCP genes. Gp96 gives really good blast hits to homologs of ta ...
Choose your target
Choose your target

... The extension of gene targeting to Drosophila and sheep will have different impacts on life as we know it. Gene targeting in Drosophila, as in mice, will be used primarily as a basic research tool. It will be used to generate mutant alleles that cannot readily be obtained by genetic screens or by P- ...
Repair of Damaged DNA
Repair of Damaged DNA

... DNA with closely related sequences 2. Site-specific 3. Transposition - occurs between unrelated sequences (e.g. Transposons; jumping genes ) Homologous Recombination Three purposes: 1. Recombinational DNA repair 2. DNA organization during meiosis (eukaryotes) 3. Genetic diversity (exchanging alleles ...
Pipe cleaner DNA
Pipe cleaner DNA

... DNA replication, the first step is to unzip the DNA strand. From the pool of available bases, students create a two-codon messenger RNA (mRNA) molecule corresponding to one of the DNA strands. The mRNA will be identical to the other DNA strand, except that uracil (white) is used instead of thymine ( ...
glossary - Diabetes Care
glossary - Diabetes Care

... the ccr gene complex (ccr) consisting of ccr genes that are responsible for the mobility of the element and its surrounding sequences; third, they have characteristic directly repeated nucleotide sequences and inverted complementary sequences at both ends; and last, they integrate into the 3' end of ...
Intrinsic and Extrinsic Factors
Intrinsic and Extrinsic Factors

... • Clones are genetically identical animals, yet neurons in clones can show differences in neural connections. • Epigenetics is the study of factors that affect gene expression, without changing the nucleotide sequence of the genes. • An important epigenetic factor that affects brain development is m ...
Molecular Genetics
Molecular Genetics

... introduces new DNA to bacterial genome (virus picked up DNA from another bacteria) Transformation – bacteria absorb DNA from surroundings and incorporate into genome ...
Genetics 310 Practice exam III-1
Genetics 310 Practice exam III-1

... Genetics 310 Practice exam III-1 1. What are the two types of molecules found in eukaryotic chromosomes? 2. True or False? ____ Man has more DNA per genome than all other organisms. ____ The number of chromosomes is a direct reflection of the amount of DNA/genome in a species. ____ All of the DNA in ...
General Genetics General concepts Genetic information is
General Genetics General concepts Genetic information is

... diversity 2. recombination is also an important tool for creation of new strains useful in biotechnology B. Plasmids = small, circular DNA molecules that can exist independently of host chromosomes (extrachromosomal) 1. have their own replication origins 2. contain few genes (usually < 30) 3. not es ...
finalexamcrib201213NED 33.5 KB
finalexamcrib201213NED 33.5 KB

... Your final exam falls out into two categories, eukaryotic regulation (which we’ve been on for about 2 weeks), which is essentially a short unit test, and is worth 64%, and cumulative content, which is essentially a mini-final and is worth 36%. The total value is 100%, all multiple choice questions, ...
Slide 1
Slide 1

... different members in family studies. • Variations within exons (genes) – lead to observable changes (e.g. eye color) • Most variations occur within introns, have little or no effect on an organism, yet they are detectable at the DNA level and can be used as markers. ...
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

... 06. Laminar air flow cabinet consists of HEPA filter. 07. Knudson medium is used for orchid culture. 08. The opine synthesized by Nop. Ti plasmid is acetosyringone. 09. pBR 322 is constructed from pUC. 10. Sodium alginate is used as fusogent. III. Complete the following 11. Hot air oven is used for ...
Chromosomes
Chromosomes

... Vehicle of trait inheritance. Each chromosome in a pair is from one parent. Each pair = homologous chromosomes. ...
Extensions for LIC
Extensions for LIC

... NOTE: It is essential to amplify a genomic gene fragment that includes a unique restriction site in order to linearize the construct prior to transfection. A 1kb fragment is sufficient for targeting, but it may be necessary to amplify a longer fragment so that it contains a unique site. The site sho ...
Purdue Agricultures Learning a new language of Life By Susan A
Purdue Agricultures Learning a new language of Life By Susan A

... Briggs specifically looks at histone methyltransferases, a type of enzyme that has been implicated in cancers. Histones are proteins around which DNA is wrapped like thread on a spool so that an entire genome fits into cells’ nucleosomes. Some forms of cancer develop because a methyl group shuts off ...
In This Issue
In This Issue

... retired faculty are replaced by new fac ulty trained in the newer biotechnologies. The investigations range from the isolation and cloning of genes to improved animal reproduction, rapid propagation of plants, and the development of disease and stress resistant crops. These studies complement the lo ...
Genomes and sequence alignment
Genomes and sequence alignment

... Not used so much anymore – single pass, high quality sequences from RTed mRNAs Can be used to catalog portions of genomes that are actively transcribed Great for organisms without high quality sequenced genomes or annotations Poor-man's RNA-seq (I can say this now; couldn't five years ago!) RNA-seq ...
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Therapeutic gene modulation

Therapeutic gene modulation refers to the practice of altering the expression of a gene at one of various stages, with a view to alleviate some form of ailment. It differs from gene therapy in that gene modulation seeks to alter the expression of an endogenous gene (perhaps through the introduction of a gene encoding a novel modulatory protein) whereas gene therapy concerns the introduction of a gene whose product aids the recipient directly.Modulation of gene expression can be mediated at the level of transcription by DNA-binding agents (which may be artificial transcription factors), small molecules, or synthetic oligonucleotides. It may also be mediated post-transcriptionally through RNA interference.
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