PowerPoint - 埼玉医科大学総合医療センター 内分泌・糖尿病内科
... increase in basal HGP, which was accompanied by significant increases in the expression of the gluconeogenic genes Fbp1, Pck1 and G6pc. Overexpression of Tcf7l2 reversed this phenotype and significantly reduced HGP. TCF7L2 silencing did not affect the half-maximal inhibitory concentration of insulin ...
... increase in basal HGP, which was accompanied by significant increases in the expression of the gluconeogenic genes Fbp1, Pck1 and G6pc. Overexpression of Tcf7l2 reversed this phenotype and significantly reduced HGP. TCF7L2 silencing did not affect the half-maximal inhibitory concentration of insulin ...
to view the Abstract Guidelines
... Nuclear Signalling Laboratory, Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia; 2Department of Genetics, La Trobe University, Bundoora, Victoria, Australia Viral based gene delivery constructs provide highly efficient gene transfer but have significa ...
... Nuclear Signalling Laboratory, Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia; 2Department of Genetics, La Trobe University, Bundoora, Victoria, Australia Viral based gene delivery constructs provide highly efficient gene transfer but have significa ...
BIO 10 Lecture 2
... same allele for a gene is homozygous. An individual that carries two different alleles for a gene is heterozygous. – In a heteroygote, only one allele is physically expressed; this allele is dominant (A) over the unexpressed, recessive (a) allele. ...
... same allele for a gene is homozygous. An individual that carries two different alleles for a gene is heterozygous. – In a heteroygote, only one allele is physically expressed; this allele is dominant (A) over the unexpressed, recessive (a) allele. ...
A PCA Based Method of Gene Expression Visual Analysis
... (GO). Looking these results, users can set an axis that divides the contributed genes (791) releelements freely (black axis of Fig. 2 and Fig. 3). Contributed com- vant to divide ALL prognoses ponents of this axis are calculated using principal components. For (Fig. 2). example, in case of Fig. 2, g ...
... (GO). Looking these results, users can set an axis that divides the contributed genes (791) releelements freely (black axis of Fig. 2 and Fig. 3). Contributed com- vant to divide ALL prognoses ponents of this axis are calculated using principal components. For (Fig. 2). example, in case of Fig. 2, g ...
DNA Fingerprinting: The Code to Identification
... bones found in a shared grave in Russia. The victims turned out to be members of the royal family, the Romanovs, who had been executed in 1918. Because the Y chromosome, part of the nuclear genome, is passed largely intact from father to son for many generations, DNA fingerprinting of the Y chromoso ...
... bones found in a shared grave in Russia. The victims turned out to be members of the royal family, the Romanovs, who had been executed in 1918. Because the Y chromosome, part of the nuclear genome, is passed largely intact from father to son for many generations, DNA fingerprinting of the Y chromoso ...
We have determined the nucleotide sequence
... been suggested that messenger stability and degradation of rp proteins may play an Important role In this control process (7, 8, 9, 1 0 ) . A computer homology search of the promoter regions of the ribosomal protein genes from Saccharomyces cerevisiae has identified two common sequences, called Homo ...
... been suggested that messenger stability and degradation of rp proteins may play an Important role In this control process (7, 8, 9, 1 0 ) . A computer homology search of the promoter regions of the ribosomal protein genes from Saccharomyces cerevisiae has identified two common sequences, called Homo ...
gene technology extra qs with mark scheme
... Some tumours grow so fast that they outgrow their blood supply and the oxygen concentration in their cells falls. Drugs are being developed that are only effective once they reach the low oxygen conditions inside a tumour cell. Here enzymes called reductase enzymes activate the drug which then kills ...
... Some tumours grow so fast that they outgrow their blood supply and the oxygen concentration in their cells falls. Drugs are being developed that are only effective once they reach the low oxygen conditions inside a tumour cell. Here enzymes called reductase enzymes activate the drug which then kills ...
Bacterial Genetics
... • Transformation: donor DNA molecule is taken up from the external environment and incorporated into the genome of the recipient cell • Conjugation: direct contact between bacterial cells; DNA from donor to recipient • Transduction: DNA goes from one bacteria to another via a phage ...
... • Transformation: donor DNA molecule is taken up from the external environment and incorporated into the genome of the recipient cell • Conjugation: direct contact between bacterial cells; DNA from donor to recipient • Transduction: DNA goes from one bacteria to another via a phage ...
You Light Up My Life
... To increase the efficiency of the translation process, several ribosomes can be aligned on one mRNA (polysome), allowing synthesis of more than one polypeptide at a time. After new polypeptide chains are complete, they may join the pool of proteins in the cytoplasm or may enter the ER for modificati ...
... To increase the efficiency of the translation process, several ribosomes can be aligned on one mRNA (polysome), allowing synthesis of more than one polypeptide at a time. After new polypeptide chains are complete, they may join the pool of proteins in the cytoplasm or may enter the ER for modificati ...
Supplementary Documents (doc 60K)
... Analysis (ChEA).1 ChEA uses a database of experimentally validated ChIP-chip, ChIPseq and ChIP-PET sites for TFs to examine the enrichment of TF binding sites at a given set of genes as compared to the whole genome. The enriched TFs were ranked by pvalue, and the top 10 TFs from each dataset were co ...
... Analysis (ChEA).1 ChEA uses a database of experimentally validated ChIP-chip, ChIPseq and ChIP-PET sites for TFs to examine the enrichment of TF binding sites at a given set of genes as compared to the whole genome. The enriched TFs were ranked by pvalue, and the top 10 TFs from each dataset were co ...
1 - Cordis
... Concerning the integron study in WP1, we have made progress in the understanding of the recombination reactions involving the cassettes. We have been able to determine which structural features in the attC sites under single stranded form conditioned the strand choice toward the bottom strand exclus ...
... Concerning the integron study in WP1, we have made progress in the understanding of the recombination reactions involving the cassettes. We have been able to determine which structural features in the attC sites under single stranded form conditioned the strand choice toward the bottom strand exclus ...
Additional file 3
... in DMSO) was spread onto the plates one to two hours before use. Blue colonies, indicating the presence of an active glucuronidase activity, were selected and re-suspended in LB medium, and plasmid DNA was purified directly from the cell suspension without further growth. Further rounds of mutagenes ...
... in DMSO) was spread onto the plates one to two hours before use. Blue colonies, indicating the presence of an active glucuronidase activity, were selected and re-suspended in LB medium, and plasmid DNA was purified directly from the cell suspension without further growth. Further rounds of mutagenes ...
Lec. 2 - DNA replication 1
... Then, Pol I degrades the RNA part with its 5’-3’ exonuclease activity, and replaces it with DNA. Pol I is not highly processive, so stops before going far. ...
... Then, Pol I degrades the RNA part with its 5’-3’ exonuclease activity, and replaces it with DNA. Pol I is not highly processive, so stops before going far. ...
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... In norma\ individuals,the trinucieotide repeat number in a specific gene may vary within this normal ranges-’and the numberof repeats is stably transmittedto future generations.In individualsaffected by, or carriers of, triplet repeat diseases,the repeat numbersare unstable and expand beyond this no ...
... In norma\ individuals,the trinucieotide repeat number in a specific gene may vary within this normal ranges-’and the numberof repeats is stably transmittedto future generations.In individualsaffected by, or carriers of, triplet repeat diseases,the repeat numbersare unstable and expand beyond this no ...
Chapter 22. Nucleic Acids
... actually "read" during the synthesis of polypeptides during translation. But each mRNA molecule acquires its sequence of nucleotides by transcription from the corresponding gene. Because DNA sequencing has become so rapid and because most genes are now being discovered at the level of DNA before the ...
... actually "read" during the synthesis of polypeptides during translation. But each mRNA molecule acquires its sequence of nucleotides by transcription from the corresponding gene. Because DNA sequencing has become so rapid and because most genes are now being discovered at the level of DNA before the ...
Advances in Genetics
... b. Animals are cloned, like Dolly the sheep, are made by taking an egg from one sheep and replacing its nucleus the nucleus from another sheep. The egg then grows into a copy of the sheep with that nucleus. 3. Genetic Engineering = A process where genes from one organism are transferred into the DNA ...
... b. Animals are cloned, like Dolly the sheep, are made by taking an egg from one sheep and replacing its nucleus the nucleus from another sheep. The egg then grows into a copy of the sheep with that nucleus. 3. Genetic Engineering = A process where genes from one organism are transferred into the DNA ...
Bioinformatics-GregoryMaurer
... Bioinformatics: Practical Application? A method of determining a set of codependent genes comprising: identifying a set of one or more genes having related gene expression data; and removing at least one gene from the set of one or more genes based on a surplus information relationship between the ...
... Bioinformatics: Practical Application? A method of determining a set of codependent genes comprising: identifying a set of one or more genes having related gene expression data; and removing at least one gene from the set of one or more genes based on a surplus information relationship between the ...
Biology Keystone Review.2016.Part 2
... 19. DNA fingerprinting – Cutting and separating DNA so repeats in the genetic code that are unique to individuals can be compared for the purpose of identification On the lines below, write T next to an example of a transgenic organism, and C next to an example of a clone. _____1. A goat that produc ...
... 19. DNA fingerprinting – Cutting and separating DNA so repeats in the genetic code that are unique to individuals can be compared for the purpose of identification On the lines below, write T next to an example of a transgenic organism, and C next to an example of a clone. _____1. A goat that produc ...
Name: Date: Period:_____ Midterm Review: Study Guide # 3
... 4. After you have finished, use this sheet as a study tool to quiz yourself. Quiz yourself by trying to answer all the questions aloud. This will probably take you a few times to feel comfortable. You are finished studying when and only when you can answer 100% of the objectives correctly without ha ...
... 4. After you have finished, use this sheet as a study tool to quiz yourself. Quiz yourself by trying to answer all the questions aloud. This will probably take you a few times to feel comfortable. You are finished studying when and only when you can answer 100% of the objectives correctly without ha ...
Genetic Diversity Of Freshwater Snails in The Peconic River Using
... Figure 3 Phylogenetic tree of the samples. It shows how the snails are related to other species. ...
... Figure 3 Phylogenetic tree of the samples. It shows how the snails are related to other species. ...
P-element-as-a-transgenesis
... 1. Inject P element plasmids containing your gene of interest and a marker (for this example, w+) into a w- 2-3 egg (this egg has already been fertilized and laid) a. 2-3: strain that contains on its third chromosome 1) Kinked (Ki) dominant visible marker and 2) P-element that encodes for a transp ...
... 1. Inject P element plasmids containing your gene of interest and a marker (for this example, w+) into a w- 2-3 egg (this egg has already been fertilized and laid) a. 2-3: strain that contains on its third chromosome 1) Kinked (Ki) dominant visible marker and 2) P-element that encodes for a transp ...
Supplemental File S9. Predisposition to Cancer
... Proto-oncogenes include positive regulator genes that produce factors that stimulate the cell cycle. Proto-oncogenes can be mutated to become oncogenes. Most proto-oncogenes found to date produce factors that stimulate the cell cycle too much. Whereas a proto-oncogene product is like a gas pedal tha ...
... Proto-oncogenes include positive regulator genes that produce factors that stimulate the cell cycle. Proto-oncogenes can be mutated to become oncogenes. Most proto-oncogenes found to date produce factors that stimulate the cell cycle too much. Whereas a proto-oncogene product is like a gas pedal tha ...
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
... 11. Outline the synthesis of a dipeptide. 12. What is Edman’s reagent? Describe its use in the determination of amino acid sequence in proteins. 13. Explain the Michaelis theory of enzyme catalysis. 14. Give the classification of lipids. Mention its biological importance. 15. Explain the types of pl ...
... 11. Outline the synthesis of a dipeptide. 12. What is Edman’s reagent? Describe its use in the determination of amino acid sequence in proteins. 13. Explain the Michaelis theory of enzyme catalysis. 14. Give the classification of lipids. Mention its biological importance. 15. Explain the types of pl ...