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SUPPLEMENTARY MATERIAL
SUPPLEMENTARY MATERIAL

... in IUGR (FOXA1 and FOXA2 reduced 2.72 and 2.73 fold, similar to the kidney and lungs respectively, while FOXA3 was not modified in heart but induced in the kidney), suggesting that the shortage in aminoacids in the heart is efficiently counterbalanced to preserve its normal function. These alteratio ...
Gene Section MYST4 (MYST histone acetyltransferase (monocytic leukemia) 4)
Gene Section MYST4 (MYST histone acetyltransferase (monocytic leukemia) 4)

... Schematic representation of MYST4 protein. H15 domain: domain in histone families 1 and 5; PHD zinc fingers: plant homeodomain (PHD) with a C4HC3-type motif, this domain is widely distributed in eukaryotes and it has been found in many chromatin regulatory factors; MOZ-SAS family region: this region ...
Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)
Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)

Introduction to Genetics
Introduction to Genetics

...  An organism with a recessive allele for a will exhibit that form only when the dominant allele for the trait is not present. ...
Non-coding RNA
Non-coding RNA

... However, their functions are generally unknown, with the exception of a few. ...
1 Comp. Funct. Genom. Copyright © (2002) John Wiley & Sons, Ltd.
1 Comp. Funct. Genom. Copyright © (2002) John Wiley & Sons, Ltd.

... genes and proteins based on shared biology. It will also aid the interpretation of large datasets created by functional genomics projects [6]. The majority of eukaryotic genome projects already use the GO annotation system, and GO annotations are being incorporated into SWISSPROT and GeneDB (see sec ...
The promoter of the Arabidopsis nuclear gene COX5b
The promoter of the Arabidopsis nuclear gene COX5b

... observed that the treatment of plants with the cytokinin BAP produces an increase in COX5b-1 transcript levels (not shown). Accordingly, GUS activity was also measured after BAP treatment in plants carrying the COX5b-1 promoter–gus fusion. As shown in Fig. 2B, this treatment produced a significant i ...
Chapter 1: The Genetic Approach to Biology Questions for Chapter 1
Chapter 1: The Genetic Approach to Biology Questions for Chapter 1

... 1. Ability to replicate faithfully (inheritance) 2. Provide an extraordinary diversity of information that can be 3. translated (changed) into structure and function of cells 4. Ability to change over time (evolution) Mutation combined with natural selection allows change over time Humans and chimps ...
A novel gene encoding a 54 kDa polypeptide is
A novel gene encoding a 54 kDa polypeptide is

... bacteria, and selection, being a growth-dependent process, may miss out organisms which require different media or temperatures. Polyclonal and monoclonal antibodies have proved to be more reliable and easy to use for detection of target organisms. However, this method of detection depends on the pr ...
Cancer Prone Disease Section Fanconi anaemia Atlas of Genetics and Cytogenetics
Cancer Prone Disease Section Fanconi anaemia Atlas of Genetics and Cytogenetics

... - Hepatocarcinoma (androgen-therapy induced) in 10%; mean age at diagnosis: 16 yrs. - Other cancers in 2-5%: in particular squamous cell carcinoma. ...
- Murdoch Research Repository
- Murdoch Research Repository

... similar predicted amino acid sequences (Table 2). Exceptions were head protein Hvp13 (77.6% amino acid similarity) and tail protein Hvp101 (86.1% similarity). The product of orfA was also somewhat different (75.4% similarity). It is not known if all strains of B. hyodysenteriae can exchange genetic ...
L - Centre for Genomic Regulation
L - Centre for Genomic Regulation

... copies have descended side by side during the history of an organism, (for example, alpha and beta hemoglobin) the genes should be called paralogous (para = in parallel). Where the homology is the result of speciation so that the history of the gene reflects the history of the species (for example a ...
Diffuse Nonepidermolytic Palmoplantar Keratoderma Caused by a
Diffuse Nonepidermolytic Palmoplantar Keratoderma Caused by a

... their pleiotropic functions, abnormal desmosomal cadherins have been linked to a growing number of inherited and acquired skin diseases.9 Desmoglein 1, a major component of the desmosome in the upper epidermal layers, is associated with the pathogenesis of at least 3 skin diseases: pemphigus foliace ...
Ultraconserved Elements in the Human Genome
Ultraconserved Elements in the Human Genome

... elements have a total of 106,767 bases • Only 6 bases have confirmed SNPs (dbSNP) • Expect 119 based on neutral evolution ...
Developmental Psychobiology: Chap5
Developmental Psychobiology: Chap5

... The research organisms chosen by scientists can have a strong influence on the types of findings that they achieve (Burian , 1992) . Had Morgan chosen sea urchins instead of Drosophila , he might not have moved so far from embryology , but his achievements in genetics would have been greatly slowed. ...
15 - Centre for Genetics Education
15 - Centre for Genetics Education

... gene expression in humans, it is an important one and provides interesting new insights into the mechanisms of gene expression. By examining genetic conditions in which problems with growth are a feature, it may be possible to uncover more imprinted genes, and in fact this approach has led to the co ...
NAC Family Genes AT1G01720 AT1G77450
NAC Family Genes AT1G01720 AT1G77450

... Mutation sequence locates to 5’UTR of gene ...
The Geographic Distribution of Monoamine Oxidase Haplotypes
The Geographic Distribution of Monoamine Oxidase Haplotypes

... isoenzymes responsible for the oxidative deamination of biogenic and xenobiotic amines. They differ in their substrate specificity and sensitivity to inhibitors (Shih et al. 1999). The genes encoding MAOA and MAOB are adjacent on the X-chromosome (Xp11.23–11.4) in a tailto-tail orientation, and they ...
Transient cold shock enhances zinc-finger nuclease
Transient cold shock enhances zinc-finger nuclease

... organisms as diverse as nematodes, flies, fish, rats and plants, as well as in rodent and human cells1–10. This flexibility is driven by the ability to engineer the zinc finger DNA–binding domain to target a ZFN to virtually any DNA sequence and the evolutionary conservation of the DNA repair pathwa ...
table of contents - The Critical Thinking Co.
table of contents - The Critical Thinking Co.

... the female cell during reproduction. 6When these cells join, they create a single cell that has two sets of chromosomes. 7Humans have 2 complete sets of 23 chromosomes (2 X 23 = 46), one set from each parent. ...
Plasticity and Resilience
Plasticity and Resilience

... which can be long or short. The length of these alleles is what is significant in the question of resilience. “People with at least one short 5-HTT allele are more prone to depression…Two long alleles, on the other hand, gave their carriers a good chance of bouncing back under negative circumstances ...
Reverse Genetic Analysis of Terminal Ear
Reverse Genetic Analysis of Terminal Ear

... support models in which these genes help maintain cells in a pluripotent state. For the first part of the thesis, analysis of lines carrying single knockouts of TEL1 and TEL2 and double knockout lines reveals a slightly accelerated rate of organogenesis, consistent with these genes normally acting t ...
PCB5065 Exam 2 - UF Plant Pathology
PCB5065 Exam 2 - UF Plant Pathology

... 6. (10 pts). Suppose you had a yeast integrative plasmid that carried two wild type yeast genes, ura-3 and leu-2. There is a restriction endonuclease cut site within both genes, EcoR1 within ura-3 and BamH1 within leu-2. There is also a HindIII site on your circular, integrative plasmid. Your yeast ...
network - bioinf leipzig
network - bioinf leipzig

... TFs are often hubs in the GRNs • TFs and their target genes TF TF TF ...
Towards safer vectors for the field release of recombinant bacteria
Towards safer vectors for the field release of recombinant bacteria

... XylS transcriptional activator is active on promoter Pm, permitting the production of the LacI repressor which then represses the lethal gef gene. (B) However, when 3-methybenzoate is absent, the lacI gene is not transcribed so that the lethal Gef protein is produced resulting in cell death. ...
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Therapeutic gene modulation

Therapeutic gene modulation refers to the practice of altering the expression of a gene at one of various stages, with a view to alleviate some form of ailment. It differs from gene therapy in that gene modulation seeks to alter the expression of an endogenous gene (perhaps through the introduction of a gene encoding a novel modulatory protein) whereas gene therapy concerns the introduction of a gene whose product aids the recipient directly.Modulation of gene expression can be mediated at the level of transcription by DNA-binding agents (which may be artificial transcription factors), small molecules, or synthetic oligonucleotides. It may also be mediated post-transcriptionally through RNA interference.
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