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gene_expression
gene_expression

... Biological process: A recognized series of events or molecular functions (e.g., cell cycle, development, metabolism) Molecular function: What does a gene’s product do? (e.g., binding, enzyme activity, receptor activity) Cellular component: Localization within the cell (e.g., membrane, nucleus, ubiqu ...
Solid Tumour Section Soft tissue tumors: Alveolar rhabdomyosarcoma in Oncology and Haematology
Solid Tumour Section Soft tissue tumors: Alveolar rhabdomyosarcoma in Oncology and Haematology

... In an analysis of patients from the IRS-IV study, patients with localized PAX3-FKHR and PAX7FKHR-positive ARMS had comparable outcomes. In contrast, among patients presenting with metastatic disease, those with PAX3-FKHR-positive tumors had a significantly poorer outcome than those with PAX7FKHR-pos ...
Roles of BRCA1 and BRCA2 in homologous recombination, DNA
Roles of BRCA1 and BRCA2 in homologous recombination, DNA

... Identification of the BRCA genes The genetic basis for familial breast cancer predisposition has become established over the past decade with the cloning of two major breast cancer susceptibility genes, BRCA1 and BRCA2 (Miki et al., 1994; Wooster et al., 1995). The BRCA1 gene was first cloned in 1994 ...
The molecular basis of cytoplasmic male sterility and
The molecular basis of cytoplasmic male sterility and

... Cytoplasmic male sterility (CMS) is a maternally inherited condition in which a plant is unable to produce functional pollen. It occurs in many plant species and is often associated with chimeric mitochondrial open reading frames. In a number of cases, transcripts originating from these altered open ...
ppt - University of Illinois at Urbana
ppt - University of Illinois at Urbana

... • Step 1: 1 6 2 3 4 5 • Step 2: 1 2 6 3 4 5 • Step 3: 1 2 3 6 4 5 ...
Frontiers in Bioscience S4, 1266-1274, June 1
Frontiers in Bioscience S4, 1266-1274, June 1

... Figure 1. This diagram illustrates how a deficiency in the given small RNA might affect spermatogenesis phenotypically. Each portion or “slice” represents potential abnormality of the cells in the seminiferous tubules undergoing spermatogenesis. The diagram correlates with the Table appended in the ...
10_30_10_Cousin_ARM
10_30_10_Cousin_ARM

... subset of an axis which shares a card with T, which shares the card, B, with I. 2CARs can be denoted using the generating (second cousin) set or the Tset antecedent. Second Cousin Association Rules once removed are those in which the antecedent Tset is generated by a subset of an axis which shares a ...
view pdf - University of Arizona
view pdf - University of Arizona

... types within the female gametophyte, determination of the exact patterns using cGFP reporters proved difficult due to low resolution of the cGFP signal. This was particularly the case for genes with reporter activity in the egg cell, the central cell, and/or the synergid cells. Using promoter:GFP ge ...
File - Mr. Doyle SUIS Science
File - Mr. Doyle SUIS Science

... • If the nucleotide sequence of a gene changes, it may result in an altered gene product, with harmful effects • Mutations • Small-scale changes in the nucleotide sequence of a cell’s DNA that alter the genetic code ...
Allele - Bryn Mawr School Faculty Web Pages
Allele - Bryn Mawr School Faculty Web Pages

... His law of particulate inheritance, states that: Each gene is controlled by two ‘factors’ With our present knowledge, we now state this idea as each gene having two alleles. Factors do not blend, but may be either dominant or recessive. Recessive factors (alleles) are masked by dominant ones. Recess ...
Gene Section SSX2 (synovial sarcoma, X breakpoint 2) in Oncology and Haematology
Gene Section SSX2 (synovial sarcoma, X breakpoint 2) in Oncology and Haematology

... (KRAB) and a C-terminal 33 amino acids domain (amino acids 155-188) with a potent transcription repressor activity (SSXRD). KRAB boxes are usually present in zinc finger proteins and are implicated in transcription repression. SSX2 lacks DNA binding motifs and is thought to function in gene regulati ...
Diagnostic Clinical Genome and Exome Sequencing
Diagnostic Clinical Genome and Exome Sequencing

... hereafter referred to as clinical genome and exome sequencing (CGES), has now entered medical practice.1 Several thousand CGES tests have already been ordered for patients, with the goal of establishing diagnoses for rare, clinically unrecognizable, or puzzling disorders that are suspected to be gen ...
Identification of genes expressed in the angiosperm female
Identification of genes expressed in the angiosperm female

... types within the female gametophyte, determination of the exact patterns using cGFP reporters proved difficult due to low resolution of the cGFP signal. This was particularly the case for genes with reporter activity in the egg cell, the central cell, and/or the synergid cells. Using promoter:GFP ge ...
Rabbit Gene Pool Natural Selection Lab 2016
Rabbit Gene Pool Natural Selection Lab 2016

... 1. You should assume that predators eat all of the white rabbits, and one half of the gray rabbits. To show this, remove the beans representing these “rabbits” from the current gene pool. Put the beans from these dead “rabbits” into the predator cup. 2. Place the remaining “surviving” rabbits into t ...
S Diagnostic Clinical Genome and Exome Sequencing review article
S Diagnostic Clinical Genome and Exome Sequencing review article

... hereafter referred to as clinical genome and exome sequencing (CGES), has now entered medical practice.1 Several thousand CGES tests have already been ordered for patients, with the goal of establishing diagnoses for rare, clinically unrecognizable, or puzzling disorders that are suspected to be gen ...
Reebops
Reebops

... Each cell in all living organisms contains hereditary information that is encoded by a chemical called DNA (deoxyribonucleic acid). DNA is an extremely long molecule. When this long, skinny DNA molecule is all coiled up and bunched together it is called a chromosome. Each chromosome is a separate pi ...
The Principle of Segregation
The Principle of Segregation

... SMALLEST size ...
A Mutation in the Eta Subunit of Pyruvate Dehydrogenase
A Mutation in the Eta Subunit of Pyruvate Dehydrogenase

... these samples were found to have the mutation, whereas concurrent cont rols prepared in the same manner had the wild type sequence. To exclude the possibility that activity in the fibroblasts was due to the presence of a normal allele, E,(X cDNA generated ...
Basic Phylogenetics and Tree Building
Basic Phylogenetics and Tree Building

... and each comparison is scored. Because low-scoring subsequences are removed from further processing, this greatly decreases the number of comparisons necessary to find an optimal alignment. • DP algorithms for sequence alignment run in O(N2) time for two sequences that have N amino acids or nucleoti ...
- Wiley Online Library
- Wiley Online Library

... This indicated that ComA could be directly responsible for the secretion of the competence-inducing molecule. ABC transporters are omnipresent in bacteria, where they function in the import and export of a wide range of different substrates (Davidson et al., 2008). In most cases, it is very difficul ...
Milestone3
Milestone3

... sequence of a motif, we would miss other (degenerate) instances of the motif. How then might we search for an instance of a gene’s TATA box, if the instance might differ from the consensus sequence? One approach would be to search for sequences of six nucleotides either that match the consensus sequ ...
CSE 181 Project guidelines
CSE 181 Project guidelines

... the bulk of the ribosome and provides structural scaffolding for the ribosome and catalyzes peptide bond formation. • tRNA (transfer RNA): The small L-shaped RNAs that deliver specific amino acids to ribosomes according to the sequence of a bound mRNA. ...
Etude Annotation
Etude Annotation

... Bxz3  for  now,  because  these  two  phages  have  annotations  in  GenBank  already—which   means  that  when  I  look  for  individual  genes  using  BLAST  on  the  NCBI  website,  I  should  see   these  genes,  and  they  will ...
MGF 110-13L/14L overlap
MGF 110-13L/14L overlap

... boxes to a given ortholog group is representative of how much of the ortholog is fused and which region. The fused ortholog groups are labelled along the deletion box connecting the fragments. The absence of a deletion box in a gene fusion indicates that the deletion that connects the two ORFs is on ...
Pelagia Research Library Exogenous gene transfer in Assam tea
Pelagia Research Library Exogenous gene transfer in Assam tea

... transformation methods, Agrobacterium-mediated gene transfer is the most advantageous because it produces defined incorporation of transgenes, low copy number, and preferential integration of transcriptionally vigorous chromosomal regions [7]. The natural ability of the phytopathogenic Agrobacterium ...
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Therapeutic gene modulation

Therapeutic gene modulation refers to the practice of altering the expression of a gene at one of various stages, with a view to alleviate some form of ailment. It differs from gene therapy in that gene modulation seeks to alter the expression of an endogenous gene (perhaps through the introduction of a gene encoding a novel modulatory protein) whereas gene therapy concerns the introduction of a gene whose product aids the recipient directly.Modulation of gene expression can be mediated at the level of transcription by DNA-binding agents (which may be artificial transcription factors), small molecules, or synthetic oligonucleotides. It may also be mediated post-transcriptionally through RNA interference.
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