The Jumping SHOX Gene—Crossover in the Pseudoautosomal
... disease is the SHOX gene (10). Inheritance of LWD is pseudoautosomal. The SHOX gene in the normal situation is present in two functional copies. In fact, one might consider PAR1 as a very small extra pair of autosomes (11), except that segregation in autosomes is independent of sex. Here we describe ...
... disease is the SHOX gene (10). Inheritance of LWD is pseudoautosomal. The SHOX gene in the normal situation is present in two functional copies. In fact, one might consider PAR1 as a very small extra pair of autosomes (11), except that segregation in autosomes is independent of sex. Here we describe ...
Journal of Autoimmunity - The Lu
... rearranged V, D (-chain only), J, and C gene segments. The recognition of antigens by -TCRs is mediated, in part, by complementarity determining regions (CDR3) spanning the V(D)J junctions of rearranged TCR genes [42]. CDR3 sequence diversity is enhanced further by the addition and deletion of ra ...
... rearranged V, D (-chain only), J, and C gene segments. The recognition of antigens by -TCRs is mediated, in part, by complementarity determining regions (CDR3) spanning the V(D)J junctions of rearranged TCR genes [42]. CDR3 sequence diversity is enhanced further by the addition and deletion of ra ...
On the maintenance of allozyme and inversion polymorphisms in
... allozynreloci were polynrorphic.On the other hand, each allozyme polymorphisÍnwas studiedin the presenceor absenceofvariation at the otherallozymelocusandin thepresence of inversionpolynoryhism.This allorvcdthe analysisof multigenicreactions ...
... allozynreloci were polynrorphic.On the other hand, each allozyme polymorphisÍnwas studiedin the presenceor absenceofvariation at the otherallozymelocusandin thepresence of inversionpolynoryhism.This allorvcdthe analysisof multigenicreactions ...
Pituitary Dwarfism In The German Shepherd Dog Part
... External or obvious characteristics aren’t the only things different about pituitary dwarfs. Blood chemistry tests show that hormones that are supposed to be circulating may be absent or at very low levels. The methods are too involved to go into here, but briefly stated, there are ways to assay the ...
... External or obvious characteristics aren’t the only things different about pituitary dwarfs. Blood chemistry tests show that hormones that are supposed to be circulating may be absent or at very low levels. The methods are too involved to go into here, but briefly stated, there are ways to assay the ...
Leukaemia Section 12p abnormalities in myeloid malignancies Atlas of Genetics and Cytogenetics
... better prognosis than patients with 12p abnormalities in general and a lower tendency to additional chromosomal rearrangements; submicroscopic deletions of 12p are much more common in lymphoid than in myeloid malignancies; a minimal interstitial deletion region is described, involving ETV6 and CDKN1 ...
... better prognosis than patients with 12p abnormalities in general and a lower tendency to additional chromosomal rearrangements; submicroscopic deletions of 12p are much more common in lymphoid than in myeloid malignancies; a minimal interstitial deletion region is described, involving ETV6 and CDKN1 ...
Genetic Control of Meat Quality Traits
... Progeny testing and artificial reproductive approaches have been used extensively in dairy cattle breeding, where AI is now used ubiquitously, and as a result milk yields of the Holstein breed have more than trebled over the past 25 years. However, this highly focused selection strategy has lead to ...
... Progeny testing and artificial reproductive approaches have been used extensively in dairy cattle breeding, where AI is now used ubiquitously, and as a result milk yields of the Holstein breed have more than trebled over the past 25 years. However, this highly focused selection strategy has lead to ...
LECTURE 1 Human Chromosomes Human Karyotype
... By the end of this lecture, the students should be able to: Describe the number, structure, and classification of human chromosomes. Explain what a Karyotype is and how it is obtained. Describe chromosomal banding and explain its use. Describe the process of in situ hybridization and the infor ...
... By the end of this lecture, the students should be able to: Describe the number, structure, and classification of human chromosomes. Explain what a Karyotype is and how it is obtained. Describe chromosomal banding and explain its use. Describe the process of in situ hybridization and the infor ...
Session 3: Gametogenesis - College of Agriculture and Life Sciences
... hampering both forward and reverse genetic analysis. PIRLs are leucine-rich repeat proteins related to Ras-group LRRs that take part in transcriptional regulation and developmental cell signaling in animals. Systematic knockout analysis of the Arabidopsis thaliana PIRL family has implicated four of ...
... hampering both forward and reverse genetic analysis. PIRLs are leucine-rich repeat proteins related to Ras-group LRRs that take part in transcriptional regulation and developmental cell signaling in animals. Systematic knockout analysis of the Arabidopsis thaliana PIRL family has implicated four of ...
Notes
... • The problem we have dealt with so far only have dealt with 2 alleles the dominant allele and the recessive allele. The dominant allele controlled the trait. • Multiple Alleles when more than 2 different alleles exist for a trait. Ex) the fruit fly Drosophilz many different eye colors are pos ...
... • The problem we have dealt with so far only have dealt with 2 alleles the dominant allele and the recessive allele. The dominant allele controlled the trait. • Multiple Alleles when more than 2 different alleles exist for a trait. Ex) the fruit fly Drosophilz many different eye colors are pos ...
Genetic and Epigenetic Regulation in Age
... lipid metabolism are also developed.33,36 Deletion/knockdown of oxidative stressYassociated genes Sod1 and Sod2, transgenic overexpression of lipid metabolism genes ApoE?4 and ApoB100, mutation of cathepsin D (Catd), and immunization with carboxyethylpyrrole all lead to varied retinal phenotype simi ...
... lipid metabolism are also developed.33,36 Deletion/knockdown of oxidative stressYassociated genes Sod1 and Sod2, transgenic overexpression of lipid metabolism genes ApoE?4 and ApoB100, mutation of cathepsin D (Catd), and immunization with carboxyethylpyrrole all lead to varied retinal phenotype simi ...
Exporter la page en pdf
... In higher eukaryotes, the absence of specific sequence motifs, marking the origins of replication has been a serious hindrance to the understanding of (i) the mechanisms that regulate the spatio-temporal replication program, and (ii) the links between origins activation, chromatin structure and trans ...
... In higher eukaryotes, the absence of specific sequence motifs, marking the origins of replication has been a serious hindrance to the understanding of (i) the mechanisms that regulate the spatio-temporal replication program, and (ii) the links between origins activation, chromatin structure and trans ...
Ethylene and Sub1
... • Ubiquitin tagged proteins are targeted for proteolysis • The proteasome constitutes 1% of total protein • Proteins are degraded at the expense of ATP • This is another example how a lot a energy is ‘sacrificed’ to achieve a high level of control ...
... • Ubiquitin tagged proteins are targeted for proteolysis • The proteasome constitutes 1% of total protein • Proteins are degraded at the expense of ATP • This is another example how a lot a energy is ‘sacrificed’ to achieve a high level of control ...
Pfx50™ DNA Polymerase - Thermo Fisher Scientific
... The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The buyer cannot sell or otherwise transfer (a) this produ ...
... The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The buyer cannot sell or otherwise transfer (a) this produ ...
Active and Inactive Genes Locafize Preferentially in the Periphery of
... sites in the nuclear periphery led to the conclusion that active genes transcribed by RNA-polymerase II are preferentially localized in these regions (Hutchison and Weintraub, 1985), this observation could not be confirmed by others (Manuelidis and Borden, 1988). Furthermore, the direct visualizatio ...
... sites in the nuclear periphery led to the conclusion that active genes transcribed by RNA-polymerase II are preferentially localized in these regions (Hutchison and Weintraub, 1985), this observation could not be confirmed by others (Manuelidis and Borden, 1988). Furthermore, the direct visualizatio ...
AnsteadSeniorHonorsThesis
... of that range is entered into Flybase in order to generate the Gbrowser displaying the genes specific to that region. Each gene is then sorted through, and genes of interest are identified by their molecular function and biological process performed. Genes associated with functions such as: DNA bind ...
... of that range is entered into Flybase in order to generate the Gbrowser displaying the genes specific to that region. Each gene is then sorted through, and genes of interest are identified by their molecular function and biological process performed. Genes associated with functions such as: DNA bind ...
Hypergraph and protein function prediction with gene expression data
... Protein function prediction plays a very important role in modern biology. Detecting the function of proteins by biological experiments is very time-consuming and difficult. Hence a lot of computational methods have been proposed to infer the functions of the proteins by using various types of infor ...
... Protein function prediction plays a very important role in modern biology. Detecting the function of proteins by biological experiments is very time-consuming and difficult. Hence a lot of computational methods have been proposed to infer the functions of the proteins by using various types of infor ...
Document
... Utilise known structure/function information to infer facts related to the predicted protein sequence Provide users with results from a number of standard algorithms/searches Provide users with cross-references (dbxrefs) to other resources Assign a simple one line description for each gene product ...
... Utilise known structure/function information to infer facts related to the predicted protein sequence Provide users with results from a number of standard algorithms/searches Provide users with cross-references (dbxrefs) to other resources Assign a simple one line description for each gene product ...
Early germline development in Caenorhabditis elegans
... end-1, a gene activated in part by SKN-1 and transcribed only in EMS descendants in wild type (Zhu et al., 1997; J. Rothman, personal communication), is also transcribed in P2 descendants in pie-1 mutants (Fig. 2; J. Rothman, personal communication; C. Tenenhaus and G. S., unpublished observations). ...
... end-1, a gene activated in part by SKN-1 and transcribed only in EMS descendants in wild type (Zhu et al., 1997; J. Rothman, personal communication), is also transcribed in P2 descendants in pie-1 mutants (Fig. 2; J. Rothman, personal communication; C. Tenenhaus and G. S., unpublished observations). ...
Statistical analysis of DNA microarray data
... maintenance and survival, but not in cell function and proliferation These genes will be similarly expressed in all samples. Difficult to identify – need to be confirmed Affymetrix GeneChip provides a set of house keeping genes based on a large set of tests on different tissues and were found ...
... maintenance and survival, but not in cell function and proliferation These genes will be similarly expressed in all samples. Difficult to identify – need to be confirmed Affymetrix GeneChip provides a set of house keeping genes based on a large set of tests on different tissues and were found ...
Evolutionary analysis of the female
... been utilized in Y chromosome-based molecular evolutionary studies in Drosophila1 and humans2, and has provided a paternal view of demography and migration in human populations3. Like mammalian and other Y chromosomes4,5, avian W chromosomes are in most cases highly heterochromatic and degenerated v ...
... been utilized in Y chromosome-based molecular evolutionary studies in Drosophila1 and humans2, and has provided a paternal view of demography and migration in human populations3. Like mammalian and other Y chromosomes4,5, avian W chromosomes are in most cases highly heterochromatic and degenerated v ...
Original Article Genetic and epigenetic association studies suggest
... Abstract: Given strong evidence implicating an important role of altered microRNA expression in cancer initiation and progression, the genes responsible for microRNA biogenesis may also play a role in tumorigenesis. Exportin-5 (XPO5) is responsible for exporting pre-miRNAs through the nuclear membra ...
... Abstract: Given strong evidence implicating an important role of altered microRNA expression in cancer initiation and progression, the genes responsible for microRNA biogenesis may also play a role in tumorigenesis. Exportin-5 (XPO5) is responsible for exporting pre-miRNAs through the nuclear membra ...
Site specific insertion of a type I rDNA dement into a unique
... insertion of the kind principally found within rDNA. The predominant type I rDNA insertion is 5kb in length, but there are also a co-terminal sub-set of shorter type I elements that share a common right hand junction with the rDNA. The insertion that we now describe is another member of this sub-set ...
... insertion of the kind principally found within rDNA. The predominant type I rDNA insertion is 5kb in length, but there are also a co-terminal sub-set of shorter type I elements that share a common right hand junction with the rDNA. The insertion that we now describe is another member of this sub-set ...
The Journal of Clinical Endocrinology
... The reason for the high frequency of the Q318X mutation is still unknown. However, a founder effect could be partly responsible for the observed distribution of this mutation in our population. Indeed, we have detected linkage desequilibrium between this mutation and a CYP21 gene polymorphism (601 C ...
... The reason for the high frequency of the Q318X mutation is still unknown. However, a founder effect could be partly responsible for the observed distribution of this mutation in our population. Indeed, we have detected linkage desequilibrium between this mutation and a CYP21 gene polymorphism (601 C ...
Specialized Transduction
... high-frequency transducing phage lysates upon lysogenic induction. The chromosomes of these phage (called λ doc, for defective, one cohesive end) are produced by an aberration of the normal packaging mechanism in which one of the DNA ends arises by cos cleavage and the other arises by a less specif ...
... high-frequency transducing phage lysates upon lysogenic induction. The chromosomes of these phage (called λ doc, for defective, one cohesive end) are produced by an aberration of the normal packaging mechanism in which one of the DNA ends arises by cos cleavage and the other arises by a less specif ...
University of Groningen Methionine
... In the current study, we elucidated the effect of methionine on the global gene expression of S. pneumoniae and demonstrated that the transcriptional regulator CmhR (SPD-0588) acts as a transcriptional activator for fhs, folD, metB-csd, metEF, metQ and spd-0431, involved in methionine uptake and uti ...
... In the current study, we elucidated the effect of methionine on the global gene expression of S. pneumoniae and demonstrated that the transcriptional regulator CmhR (SPD-0588) acts as a transcriptional activator for fhs, folD, metB-csd, metEF, metQ and spd-0431, involved in methionine uptake and uti ...