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Nucleotide Sequence Databases
Nucleotide Sequence Databases

... • much less efficient than prokaryotes; less than 5% of human genome codes for protein • genes transcribed after a promoter region; but process may be strongly influenced by sequence elements relatively far away ...
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What is a GENE? - West East University

... carried out of the nucleus into the cell's cytoplasm. The RNA combines with protein/nucleic acid organelles in the cytoplasm called ribosomes. Special molecules of RNA (called transfer RNA or tRNA) bring amino acides to the ribosome, which can then construct a long chain of amino acids by reading th ...
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Make an Alien Lab
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... • Explain what is meant by gene expression and why genes need to be expressed to have an effect on an organism’s characteristics Genes need to be expressed  mRNA  protein (or tRNA or rRNA). Genotype determines phenotype but to affect the phenotype, the proteins specified by the genes need to be s ...
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Primary transcript



A primary transcript is the single-stranded ribonucleic acid (RNA) product synthesized by transcription of DNA, and processed to yield various mature RNA products such as mRNAs, tRNAs, and rRNAs. The primary transcripts designated to be mRNAs are modified in preparation for translation. For example, a precursor messenger RNA (pre-mRNA) is a type of primary transcript that becomes a messenger RNA (mRNA) after processing.There are several steps contributing to the production of primary transcripts. All these steps involve a series of interactions to initiate and complete the transcription of DNA in the nucleus of eukaryotes. Certain factors play key roles in the activation and inhibition of transcription, where they regulate primary transcript production. Transcription produces primary transcripts that are further modified by several processes. These processes include the 5' cap, 3'-polyadenylation, and alternative splicing. In particular, alternative splicing directly contributes to the diversity of mRNA found in cells. The modifications of primary transcripts have been further studied in research seeking greater knowledge of the role and significance of these transcripts. Experimental studies based on molecular changes to primary transcripts the processes before and after transcription have led to greater understanding of diseases involving primary transcripts.
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