MyGene.info Documentation
... MyGene.info provides simple-to-use REST web services to query/retrieve gene annotation data. It’s designed with simplicity and performance emphasized. A typical use case is to use it to power a web application which requires querying genes and obtaining common gene annotations. For example, MyGene.i ...
... MyGene.info provides simple-to-use REST web services to query/retrieve gene annotation data. It’s designed with simplicity and performance emphasized. A typical use case is to use it to power a web application which requires querying genes and obtaining common gene annotations. For example, MyGene.i ...
A caudal mRNA gradient controls posterior development in the wasp
... Two to 3 hours after egg laying (hAEL) at 28°C, during pole cell formation, a zygotic gradient of Nvit cad expression forms in the syncytial embryo. Although the exact timing of midblastula transition in Nasonia is not known, it is likely that this expression is zygotic as it coincides with the onse ...
... Two to 3 hours after egg laying (hAEL) at 28°C, during pole cell formation, a zygotic gradient of Nvit cad expression forms in the syncytial embryo. Although the exact timing of midblastula transition in Nasonia is not known, it is likely that this expression is zygotic as it coincides with the onse ...
`Candidatus Phytoplasma mali`, `Candidatus Phytoplasma pyri` and
... generated previously. Additional work was carried out as follows. Sequence and RFLP analyses of ribosomal fragments were performed by using rDNA that was amplified with the primer pair P1/P7 (Deng & Hiruki, 1991; Schneider et al., 1995) and extended from the 59 end of the 16S rRNA gene to the 59 reg ...
... generated previously. Additional work was carried out as follows. Sequence and RFLP analyses of ribosomal fragments were performed by using rDNA that was amplified with the primer pair P1/P7 (Deng & Hiruki, 1991; Schneider et al., 1995) and extended from the 59 end of the 16S rRNA gene to the 59 reg ...
Product description P048-C1-0315 LMNA-MYOT - MRC
... The P048-C1 probemix contains probes for all 12 exons of the LMNA gene. Two probes are present for exon 1. This probemix furthermore contains probes for all exons of the ZMPSTE24, MYOT and CAV3 genes. Finally, 9 reference probes are included in this probemix, detecting several different autosomal ch ...
... The P048-C1 probemix contains probes for all 12 exons of the LMNA gene. Two probes are present for exon 1. This probemix furthermore contains probes for all exons of the ZMPSTE24, MYOT and CAV3 genes. Finally, 9 reference probes are included in this probemix, detecting several different autosomal ch ...
The amelogenin gene
... of human amelogenin protein including signal peptide of 16 residues on both X- and V-chromosomes were identified. The mature human amelogenin from the X-chromosome skipping exon 4 is a protein of 19.8 kDa with 175 amino acid residues and which trom Y is a 20 kDa protein with 176 amino acids. The met ...
... of human amelogenin protein including signal peptide of 16 residues on both X- and V-chromosomes were identified. The mature human amelogenin from the X-chromosome skipping exon 4 is a protein of 19.8 kDa with 175 amino acid residues and which trom Y is a 20 kDa protein with 176 amino acids. The met ...
Branching Processes in Biology - Rice Statistics
... • Amplification of genes coding for the enzyme dihydrofolate reductase (DHFR) has been associated with cellular resistance to the anticancer drug methotrexate (MTX). • A resistant population with an increased number of DHFR gene copies per cell can be obtained after a sensitive population is grown i ...
... • Amplification of genes coding for the enzyme dihydrofolate reductase (DHFR) has been associated with cellular resistance to the anticancer drug methotrexate (MTX). • A resistant population with an increased number of DHFR gene copies per cell can be obtained after a sensitive population is grown i ...
Unconventional initiator tRNAs sustain Escherichia coli
... three consecutive G-C base (3G-C) pairs in its anticodon stem at positions 29–41, 30–40, and 31–39 (Fig. 1). Although formylation is not found in archaea and eukaryotes, the 3G-C pairs remain universal; they are conserved across all domains of life. They have been shown to be essential for the P-sit ...
... three consecutive G-C base (3G-C) pairs in its anticodon stem at positions 29–41, 30–40, and 31–39 (Fig. 1). Although formylation is not found in archaea and eukaryotes, the 3G-C pairs remain universal; they are conserved across all domains of life. They have been shown to be essential for the P-sit ...
Development of a repressible mycobacterial
... them during experimental infection (7–9). Even though these tools proved to be quite useful, they have the disadvantage that Tc functions as an inducer of gene expression and has therefore to be removed to silence the gene under investigation. For this reason Guo et al. (13) developed a modified syst ...
... them during experimental infection (7–9). Even though these tools proved to be quite useful, they have the disadvantage that Tc functions as an inducer of gene expression and has therefore to be removed to silence the gene under investigation. For this reason Guo et al. (13) developed a modified syst ...
Control of DNA excision efficiency in Paramecium
... micronuclei undergo meiosis, whereas the macronuclei degenerate. The fusion of two gametic nuclei produces a zygotic nucleus. This nucleus divides twice and the daughter nuclei then differentiate into a micronucleus or a macronucleus. In the second case, the whole genome is processed through chromos ...
... micronuclei undergo meiosis, whereas the macronuclei degenerate. The fusion of two gametic nuclei produces a zygotic nucleus. This nucleus divides twice and the daughter nuclei then differentiate into a micronucleus or a macronucleus. In the second case, the whole genome is processed through chromos ...
PH4 of Petunia Is an R2R3 MYB Protein That Activates
... of the pathway, in all pigmented tissues (Quattrocchio et al., 1993) and encode a basic-helix-loop-helix (BHLH) transcription factor and a WD40 protein, respectively (de Vetten et al., 1997; Spelt et al., 2000). AN2 encodes a MYB-type transcription factor whose function appears to be (partially) red ...
... of the pathway, in all pigmented tissues (Quattrocchio et al., 1993) and encode a basic-helix-loop-helix (BHLH) transcription factor and a WD40 protein, respectively (de Vetten et al., 1997; Spelt et al., 2000). AN2 encodes a MYB-type transcription factor whose function appears to be (partially) red ...
Genetic interactions between scribbler, Atrophin and
... Wehn and Campbell: Gro, Sbb and Atro and repression INTRODUCTION An essential feature of all eukaryotic cells is the ability to transcribe only a subset of the genes present in their genomes. Whether a gene is transcribed or not is largely dependent upon the presence and activity of specific regula ...
... Wehn and Campbell: Gro, Sbb and Atro and repression INTRODUCTION An essential feature of all eukaryotic cells is the ability to transcribe only a subset of the genes present in their genomes. Whether a gene is transcribed or not is largely dependent upon the presence and activity of specific regula ...
Affymetrix Software User Manuals
... Subject to the Affymetrix terms and conditions that govern your use of Affymetrix products, Affymetrix grants you a nonexclusive, non-transferable, non-sublicensable license to use this Affymetrix product only in accordance with the manual and written instructions provided by Affymetrix. You underst ...
... Subject to the Affymetrix terms and conditions that govern your use of Affymetrix products, Affymetrix grants you a nonexclusive, non-transferable, non-sublicensable license to use this Affymetrix product only in accordance with the manual and written instructions provided by Affymetrix. You underst ...
Notes for Chaper 4 of the Jones/Pevzer book
... • Nucleotides in motifs encode for a message in the “genetic” language. Symbols in “The Gold Bug” encode for a message in English • In order to solve the problem, we analyze the frequencies of patterns in DNA/Gold Bug message. • Knowledge of established regulatory motifs makes the Motif Finding prob ...
... • Nucleotides in motifs encode for a message in the “genetic” language. Symbols in “The Gold Bug” encode for a message in English • In order to solve the problem, we analyze the frequencies of patterns in DNA/Gold Bug message. • Knowledge of established regulatory motifs makes the Motif Finding prob ...
Endothelin signaling activates Mef2c expression in the neural crest
... transgenic mice were crossed into wild-type (B), Ednra-null (C), Ednrb-null (D) and Ednra; Ednrb double-null (E) backgrounds and were analyzed by X-gal staining at E9.5. (F,G) Bosentan, a dual Endothelin receptor antagonist, inhibited Mef2c-F1 enhancer activity in the neural crest of explanted E9.5 ...
... transgenic mice were crossed into wild-type (B), Ednra-null (C), Ednrb-null (D) and Ednra; Ednrb double-null (E) backgrounds and were analyzed by X-gal staining at E9.5. (F,G) Bosentan, a dual Endothelin receptor antagonist, inhibited Mef2c-F1 enhancer activity in the neural crest of explanted E9.5 ...
Leukaemia Section 3q rearrangements in myeloid malignancies Atlas of Genetics and Cytogenetics
... conflicting indicating that further experiments are needed to clarify the exact role of both evolutionary conserved transcripts. DNA/RNA EVI1 spans approximately 50 kb and contains 12 exons, 10 of which are coding. Translation starts in exon 3. MDS1/EVI1 results from intergenic splicing from MDS1 an ...
... conflicting indicating that further experiments are needed to clarify the exact role of both evolutionary conserved transcripts. DNA/RNA EVI1 spans approximately 50 kb and contains 12 exons, 10 of which are coding. Translation starts in exon 3. MDS1/EVI1 results from intergenic splicing from MDS1 an ...
PDF reprint - Stanford Medicine
... visceral muscles develop. Jeb protein is produced in somatic muscle precursors and taken up by visceral muscle precursors. jeb reveals a signaling process in which somatic muscle precursors support the proper migration and differentiation of visceral muscle cells. Later in embryogenesis, jeb is tran ...
... visceral muscles develop. Jeb protein is produced in somatic muscle precursors and taken up by visceral muscle precursors. jeb reveals a signaling process in which somatic muscle precursors support the proper migration and differentiation of visceral muscle cells. Later in embryogenesis, jeb is tran ...
SPATULA, a bHLH carpel development gene
... Genetic analysis has revealed that SPT acts in parallel with two other genes to specify all components of the mature gynoecium (Alvarez and Smyth, 1999). The C-class gene AGAMOUS (AG) specifically promotes the characteristic cellular morphology of the carpel wall and the development of a stylar apic ...
... Genetic analysis has revealed that SPT acts in parallel with two other genes to specify all components of the mature gynoecium (Alvarez and Smyth, 1999). The C-class gene AGAMOUS (AG) specifically promotes the characteristic cellular morphology of the carpel wall and the development of a stylar apic ...
Molecular mechanics of the interactions of spermine with DNA: DNA
... Polyamines are simple, polycatioruc ligands present in prokaryotic and eukaryotic cells that are fundamentally important for cellular growth (reviewed in 1,2). The regulation of their synthesis and metabolism is intricate (3); after growth stimulation, the concentrations of intracellular polyamines ...
... Polyamines are simple, polycatioruc ligands present in prokaryotic and eukaryotic cells that are fundamentally important for cellular growth (reviewed in 1,2). The regulation of their synthesis and metabolism is intricate (3); after growth stimulation, the concentrations of intracellular polyamines ...
Are Restriction Enzymes Recognition Sites Underrepresented in the
... usually from Type IIS. These are designed to recognize and cleave large target DNA. They are not covered in the scope of this master’s thesis (7). DNA methylation in bacteria DNA methylation in bacterial cells consists of two mechanisms, endogenous DNA methylation and exogenous DNA methylation. Endo ...
... usually from Type IIS. These are designed to recognize and cleave large target DNA. They are not covered in the scope of this master’s thesis (7). DNA methylation in bacteria DNA methylation in bacterial cells consists of two mechanisms, endogenous DNA methylation and exogenous DNA methylation. Endo ...
A Physical Gene Map of the Bacteriophage P22 Late
... EcoRI cleavage at the first site counterclockwise from pat (Jackson et CL, 1978a). The smaller Sal1 fragment (Sal1 B) (see Fig. 1) is derived in an analogous fashion from a molecular end at pat plus a single Sal1 cleavage. Double digestion with EcoRI plus Sal1 generates two new fragments (3.6 and 5. ...
... EcoRI cleavage at the first site counterclockwise from pat (Jackson et CL, 1978a). The smaller Sal1 fragment (Sal1 B) (see Fig. 1) is derived in an analogous fashion from a molecular end at pat plus a single Sal1 cleavage. Double digestion with EcoRI plus Sal1 generates two new fragments (3.6 and 5. ...
Product description P003-D1 MLH1-MSH2-v01 - MRC
... Arranging probes according to chromosomal location facilitates interpretation of the results and may reveal more subtle changes such as those observed in mosaic cases. Analysis of parental samples may be necessary for correct interpretation of complex results. False positive results: Please note tha ...
... Arranging probes according to chromosomal location facilitates interpretation of the results and may reveal more subtle changes such as those observed in mosaic cases. Analysis of parental samples may be necessary for correct interpretation of complex results. False positive results: Please note tha ...
Primary transcript
A primary transcript is the single-stranded ribonucleic acid (RNA) product synthesized by transcription of DNA, and processed to yield various mature RNA products such as mRNAs, tRNAs, and rRNAs. The primary transcripts designated to be mRNAs are modified in preparation for translation. For example, a precursor messenger RNA (pre-mRNA) is a type of primary transcript that becomes a messenger RNA (mRNA) after processing.There are several steps contributing to the production of primary transcripts. All these steps involve a series of interactions to initiate and complete the transcription of DNA in the nucleus of eukaryotes. Certain factors play key roles in the activation and inhibition of transcription, where they regulate primary transcript production. Transcription produces primary transcripts that are further modified by several processes. These processes include the 5' cap, 3'-polyadenylation, and alternative splicing. In particular, alternative splicing directly contributes to the diversity of mRNA found in cells. The modifications of primary transcripts have been further studied in research seeking greater knowledge of the role and significance of these transcripts. Experimental studies based on molecular changes to primary transcripts the processes before and after transcription have led to greater understanding of diseases involving primary transcripts.