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SICB 2014 Annual Meeting Abstracts
SICB 2014 Annual Meeting Abstracts

... gene regulatory regions through a highly conserved DNA binding domain (DBD) composed of three C−terminal C2H2 zinc fingers (KLF−DBD). Members of the Klf gene family influence transcription via interactions with other transcription factors, cofactors, chromatin remodeling factors, and transcriptional ...
Mutations - Northeast High School
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BIOL 1107 - Chapter 17
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... A mad scientist, after watching too many fantasy movies, decides to breed mutant Drosophila in the model of dragons. Mutants with super powers have the dominant alleles for Flame Breath (F), Neon Skin (N), Red Eyes (R), and Dragon Wings (D). A homozygous dominant “Dragon Fly” (Drosophila drago) whic ...
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... who have one copy of the allele, which can come from just one parent. For a recessive allele to produce a recessive phenotype, the individual must have two copies, one from each parent. An individual with one dominant and one recessive allele for a gene will have the dominant phenotype. They are gen ...
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... system, TruSeqTM RNA sample preparation, which employs polyA selection for mRNA enrichment and Invitrogen’s RiboMinusTM kit which depletes rRNA. We considered the following criteria in evaluating the RNA-seq methods, some of which are described in literature (10): library complexity, the number of u ...
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... ribosomes (2), while the SS is encoded in nuclear genome and synthesized on cytoplasmic ribosomes as a precursor protein of MW 20,000 which is transported into chloroplast, processed to its mature size and then assembled with the LS protein (3). Recently the SS genes of wheat and soybean are shown t ...
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PNAS
PNAS

... 12407) describe the trade-offs between clustering sensors to reduce estimation noise and distributing clusters to capture incoming signals that vary in space and time. The authors found that optimal sensor configurations are dependent on sensor density and sampling time, and that phase transitions d ...
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Primary transcript



A primary transcript is the single-stranded ribonucleic acid (RNA) product synthesized by transcription of DNA, and processed to yield various mature RNA products such as mRNAs, tRNAs, and rRNAs. The primary transcripts designated to be mRNAs are modified in preparation for translation. For example, a precursor messenger RNA (pre-mRNA) is a type of primary transcript that becomes a messenger RNA (mRNA) after processing.There are several steps contributing to the production of primary transcripts. All these steps involve a series of interactions to initiate and complete the transcription of DNA in the nucleus of eukaryotes. Certain factors play key roles in the activation and inhibition of transcription, where they regulate primary transcript production. Transcription produces primary transcripts that are further modified by several processes. These processes include the 5' cap, 3'-polyadenylation, and alternative splicing. In particular, alternative splicing directly contributes to the diversity of mRNA found in cells. The modifications of primary transcripts have been further studied in research seeking greater knowledge of the role and significance of these transcripts. Experimental studies based on molecular changes to primary transcripts the processes before and after transcription have led to greater understanding of diseases involving primary transcripts.
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