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Stamm revision
Stamm revision

... The yeast Saccharomyces cerevisiae has been used extensively to investigate functions of RNA and protein components of the spliceosome. As many of the yeast core splicing factors are evolutionarily conserved with human counterparts, information gained in yeast can be directly applied to humans. The ...
Severe Combined Immunodeficiency Genetic Testing
Severe Combined Immunodeficiency Genetic Testing

... the way they should. Gene mutations may result in health problems, and they may be passed from parent to child (inherited). Mutations in the IL2RG, ADA, and IL7R genes are the most common causes of SCID In the US, but other gene mutations are also known to cause the disease.6 Each of these genes pla ...
The evolution of sex chromosomes: similarities and differences
The evolution of sex chromosomes: similarities and differences

... Haldane (1922, p. 107): “If sex were determined by a single factor, it is very difficult to see what advantage there could be in its being linked with other factors)” (Sex ratio and unisexual sterility in hybrid animals. J. Genetics 12:101-109) – Nei (1969, 1970): models for lack of recombination an ...
Modulation of CTCF Insulator Function by
Modulation of CTCF Insulator Function by

... of Molecular Cell reveals a novel mechanism in which noncoding RNA transcription and nucleosome repositioning evicts CTCF from a regulatory element to facilitate induction of a nearby gene. The zinc finger protein CTCF binds directly to specific DNA sequences and plays multiple roles in the regulati ...
In search of essentiality: Mollicute-specific genes
In search of essentiality: Mollicute-specific genes

... and biogenesis), as expected (Santos et al. and Borges et al., in the present issue), contains the highest number of genes (82) (Table 1). All COG categories involved in metabolism (E, F, G, H, I and P) were clustered (Arraes et al., Balaião et al., and Staats et al., in the present issue). The F0F1 ...
Evaluation of the Y-Chromosome Structure
Evaluation of the Y-Chromosome Structure

... Genomic studies undertaken by Skaletsky et al. (2003) provided evidence of an abundance of intrachromosomal recombination resulting in what was known as the non-recombining region, the NRY, being renamed to the male specific region, the MSY (Skaletsky et al. 2003). ...
On the monophyly of chromalveolates using a six
On the monophyly of chromalveolates using a six

... molecular phylogenetics. Currently, there are five hypothesized major lineages or ‘supergroups’ of eukaryotes. One of these, the chromalveolates, represents a large fraction of protist and algal diversity. The chromalveolate hypothesis was originally based on similarities between the photosynthetic ...
Evolution of Immunoglobulin Kappa Chain Variable Region
Evolution of Immunoglobulin Kappa Chain Variable Region

... can be grouped into three major monophyletic clusters, the cartilaginous fish, bony fish and amphibian, and mammalian clusters, and that the cartilaginous fish cluster first separated from the rest of the Vk genes and then the remaining two clusters diverged. The mammalian Vk genes can further be di ...
EFFECT OF FSH β-SUB UNIT AND FSHR GENES
EFFECT OF FSH β-SUB UNIT AND FSHR GENES

... species. Mostly B allele and C allele for FSH β-sub unit and FSHR respectively have a high number in Bos taurus species while those were in contrast in Bos indicus species. The highest heterozygosity was found in FH cattle (0.250) for FSH β-sub unit and Brahman (0.333) for FSHR. Significant effect w ...
Regulation of CO2 fixation via the Calvin cycle in the facultative
Regulation of CO2 fixation via the Calvin cycle in the facultative

... assays.CbbR binds to two inverted repeats (IR' and IRr) in the cbbR-cbbL intergenic region (Fig.la). Binding of CbbR to IR, and IR2 occurs in a cooperativemanner; binding of CbbR to IR, is a prerequisitefor CbbR binding to IR, (chapter VI). In accordancewith these in vitro studies is the observation ...
this PDF file
this PDF file

... When 5A7 was first isolated, it was identified as a “brown” non-photosynthetic mutant. Spectrophotometric and HPLC results have shown that 5A7 lacks detectable Chl (Fig. 3; Table 1). Collaborative work with Dr. Bernhard Grimm of Humboldt University (Berlin, Germany), has revealed that 5A7 over-accum ...
The role of xylulokinase in Saccharomyces cerevisiae xylulose
The role of xylulokinase in Saccharomyces cerevisiae xylulose

... The ratio between growth on glucose, doubling time 2 h, and growth on D-xylulose, doubling time 12 h, is now 6, which is closer to the ratio observed for other yeasts. However, despite over-expressing xylulokinase, the growth rate on xylulose is still several fold lower than on glucose. In S. pombe ...
Molecular mapping of the rust resistance gene R4 to a large NBS
Molecular mapping of the rust resistance gene R4 to a large NBS

... Rust resistance gene R4 in the germplasm line HA-R3 was derived from the Argentinean open-pollinated variety ‘Charata INTA’ (Gulya 1985). The origin of its rust resistance gene can be traced to wild annual Helianthus species. Charata INTA was selected from the cross between Russian lines and wild su ...
Molecular cloning and characterization of cm3 gene, from t
Molecular cloning and characterization of cm3 gene, from t

... wild emmer wheat showed a wide range of diversity in WDAI, WMAI both between and within populations, he also found that alpha -amylase inhibitors are adaptively selected under different environments according to population and codon analysis. However in the present study no significant changes in CM ...
LOSS OF HETEROZYGOSITY DUE TO SHORT-TRACT AND LONG-TRACT SACCHAROMYCES CEREVISIAE Thomas Coates
LOSS OF HETEROZYGOSITY DUE TO SHORT-TRACT AND LONG-TRACT SACCHAROMYCES CEREVISIAE Thomas Coates

... al., 2006). Loss of FHIT can be indicative of the early stages of tumorigenesis (Ingvarsson, 2001). Overlapping in sequence with the FHIT gene is the large (~4Mb) CFS FRA3B, notable as being the most commonly broken in lymphocytes (the cell type traditionally used in CFS research) and first charact ...
Novel visual system homeobox 1 gene mutations in Turkish patients
Novel visual system homeobox 1 gene mutations in Turkish patients

... identified linkage regions can be helpful in understanding exome or genome sequencing data. The genetic heterogeneity of KC requires the identification and replication of novel genetic mutations; therefore, our results might help clarify the genetic basis of KC. The VSX1 variants reported in various ...
Correlations Between Gene Expression and Gene Conservation in
Correlations Between Gene Expression and Gene Conservation in

... (P < 10ⳮ21). Moreover, pombe-specific genes were underrepresented among genes repressed during sexual differentiation, contributing only 5.9% of those genes (P < 10ⳮ7). We defined “pombe-specific genes” as those not shared with the S. cerevisiae and C. elegans genomes. To confirm these results, we u ...
A pseudogene cluster in the leader region of the Euglena
A pseudogene cluster in the leader region of the Euglena

... base pairing 1n stem regions. These alternations rendered 1t unable to function normally, and thus this gene was identified as a pseudogene. Similar consideration might also be possible for the DNA segment corresponding to the tRNA Ala gene region, although, in this case, the tRNA A1a anticodon 1s a ...
Genetics - Faperta UGM
Genetics - Faperta UGM

...  Some expected phenotypes do not appear among offspring  Labrador retrievers one gene locus affects coat color by controlling how densely the pigment eumelanin is deposited in the fur.  A dominant allele (B) produces a black coat while the recessive allele (b) produces a brown coat  However, a s ...
Identification of a NodD repressible gene
Identification of a NodD repressible gene

... region that could correspond to a gene transcribed divergently from nodM [Fig. 1(B)]. The predicted translation site is only 41 bp from the end of the nodM nod box [Fig. 1(B)] suggesting that if this is an expressed gene, the px3 and nodM promoters would be likely to overlap. Database searches of tr ...
Exploring biochemistry using metabolic pathways
Exploring biochemistry using metabolic pathways

... think  is  happening  with  these  bacteria.       2. Advanced  question:    You  will  need  to  create  two  new  genome  groups,  one   with  all  the  complete  genomes  found  in  Brucella,  and  another  from  all  the   compl ...
B/B a/a - kcpe-kcse
B/B a/a - kcpe-kcse

... Sickle cell anemia may be the result of a genetic mutation that happened in malariaprone regions like Africa thousands of years ago. People with sickle cell trait may have been more likely to survive malaria epidemics and because they survived when others did not, this allowed the trait to be passe ...
The PTC Gene - Wilbur World of Science
The PTC Gene - Wilbur World of Science

... PTC sensitivity is often used as an example of a simple Mendelian trait with dominant inheritance. However, tasters vary greatly in their sensitivity to PTC. And while the PTC gene has about 85% of the total influence over whether someone is a taster or a non-taster, there are many other things that ...
Histone genes of Volvox carteri: DNA sequence and organization of
Histone genes of Volvox carteri: DNA sequence and organization of

... genes (9), differences in gene structure between replication type (H3.1 and H3.2) and replacement-type (H3.3) gene families are paralleled by specific differences in amino acid sequences, codon usage and mode of expression. Based on these data a heterodox evolutionary model in which the intron-beari ...
MayerFrankiPoster
MayerFrankiPoster

... pharmaceuticals, plastics, and biofuels. One approach to the production of bioproducts is to use cyanobacteria, which are microalgae that derive energy from sunlight and carbon from CO2. Our group had genetically modified the cyanobacterium Synechococcus sp. PCC 7002 to produce isoprene. However, fo ...
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