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Research in Microbiology
Research in Microbiology

... 3.1. P. polymyxa Spo0A, Spo0B and Spo0F Signal transduction for sporulation is mediated by the phosphorelay system, which is highly conserved in sporeforming Bacillus species (Stephenson and Hoch, 2002). In the system, histidine kinase phosphorylates Spo0F, and the phosphate group from the Spo0F is ...
Processing the RefSeq and CCDS Annotation Datasets Using the SAS System: Creation of Gene Reference
Processing the RefSeq and CCDS Annotation Datasets Using the SAS System: Creation of Gene Reference

... of STRAND, either Lines 37-171 or Lines 174-331 are executed. The authors avoided using ELSE IF for two reasons: the computational require of two exclusive IF statements is negligible and indenting made the code more difficult to read on a smaller screen. In either set of IF-THEN-DO-END statements, ...
Complete comparative genomic analysis of two field isolates of
Complete comparative genomic analysis of two field isolates of

... variable region is located between hr1 and orf31 (bro-c) (v90/4, 15?0–27?1 kb; v90/2, 15?0–28?3 kb). In this 12?1 kb region (7?7 % of the genome), there are 261 of the 521 point mutations, accounting for 50 % of the total nucleotide changes. Of the 261 point mutations, 82 cause nonsynonymous changes ...
Autosomal and X-chromosome imprinting
Autosomal and X-chromosome imprinting

... reviews (Searle and Beechey, 1985; Cattanach, 1986; Cattanach and Beechey, 1990). Suffice to say here that by intercrossing heterozygotes for Robertsonian translocations that exhibit high rates of non-disjunction, animals can be produced which have two homologues of a selected chromosome from one pa ...
Role of two-component systems in the virulence of Streptococcus
Role of two-component systems in the virulence of Streptococcus

... membrane-associated sensor histidine kinase (HK) and a cytoplasmic cognate response regulator (RR). Upon receipt of a specific external stimulus the kinase domain of the HK sensor protein is activated to autophosphorylate a conserved histidine residue. HK proteins tend to be found as homodimers that ...
Affymetrix Software User Manuals
Affymetrix Software User Manuals

... Subject to the Affymetrix terms and conditions that govern your use of Affymetrix products, Affymetrix grants you a nonexclusive, non-transferable, non-sublicensable license to use this Affymetrix product only in accordance with the manual and written instructions provided by Affymetrix. You underst ...
Codon usage bias from tRNA`s point of view
Codon usage bias from tRNA`s point of view

... The selection-mutation-drift theory of codon usage plays a major role in the theory of molecular evolution by explaining the co-evolution of codon usage bias and tRNA content in the framework of translation optimization. Because most studies have focused only on codon usage, we analyzed the tRNA gen ...
PDF
PDF

... affects both H19 and Igf2 expression (Thorvaldsen et al., 1998). This sequence binds the insulator protein CTCF on the unmethylated maternal allele, thereby creating a boundary between the downstream enhancers and the Igf2 maternal allele (Hark et al., 2000). In order to decipher the role of the H19 ...
Optimizing selection for quantitative traits with information on an
Optimizing selection for quantitative traits with information on an

... Methods to formulate and maximize response to selection for a quantitative trait over multiple generations when information on a quantitative trait locus (major gene) is available were developed to investigate and optimize response to selection in mixed inheritance models. Deterministic models with ...
Inference of homologous recombination in bacteria using whole
Inference of homologous recombination in bacteria using whole

... This is a key property of our model, which does not hold in the Ancestral Recombination ...
Inheritance involved in the pathogenesis of idiopathic scoliosis
Inheritance involved in the pathogenesis of idiopathic scoliosis

... Radiation therapy, tumors and syrinx formation have also been implicated as etiologies of scoliosis (Richards and Vitale, 2008). To date, the genetics underlying idiopathic curvature have not been identified. This is most likely a consequence of several factors, including inconsistent pedigree const ...
Effect of the Polymorphisms of Keratin Associated Protein 8.2 Gene
Effect of the Polymorphisms of Keratin Associated Protein 8.2 Gene

... determine associations between the genotype and fibre traits in Chinese Inner Mongolia cashmere goats. The fibre traits data investigated were cashmere fibre diameter, combed cashmere weight, cashmere fibre length and guard hair length. Five hundred and forty-two animals were used to detect polymorp ...
From DNA to diversity: molecular genetics and the evolution of
From DNA to diversity: molecular genetics and the evolution of

... anatomy of genetic switches, the genetic switches controling animal anatomy may be even more appealing. Not only do they control the striking patterns of gene expression within developing embryos, but as we shall see, they are also key to understanding how the wonderful, but presently dwindling, div ...
THE GENETICS AND REPRODUCTIVE ISOLATING MECHANISMS
THE GENETICS AND REPRODUCTIVE ISOLATING MECHANISMS

... of the environment of Zagreb, ranging eastwards to the line MariborZidani most approximately, where the last small populations of a light bryonix can be found. The most important genetic results were obtained from the cross "III" which could be brought up to the 14th generation without introduction ...
SNP Discovery and Genotyping Workshop (PowerPoint)
SNP Discovery and Genotyping Workshop (PowerPoint)

... Where do I find SNPs to use in my association studies? (e.g. databases, direct resequencing) 2. SNP Selection: How do I choose SNPs that are informative? (i.e. assessing SNP correlation - linkage disequilibrium) 3. SNP Associations: What analyses can I perform after genotyping these SNPs? (e.g. sing ...
Synonymous codon usage patterns in different parasitic
Synonymous codon usage patterns in different parasitic

... Most amino acids are encoded by multiple codons. In most cases, the synonymous codons are not used randomly in different genomes (Grantham et al., 1980; Lloyd and Sharp, 1992). Furthermore, the pattern of codon usage can vary considerably among organisms, and also among genes from the same genome. C ...
NCBI Molecular Biology Resources
NCBI Molecular Biology Resources

... All polymorphisms in the TPO gene DNA/RNA sequences similar to M17755 Graphical view of TPO gene annotation Human phenotypes involving TPO ...
Codon optimization of Col H gene encoding Clostridium
Codon optimization of Col H gene encoding Clostridium

... site obstructs translation initiation. On the other hand, GC-poor mRNAs cannot fold strongly and ...
The Wnt code: cnidarians signal the way
The Wnt code: cnidarians signal the way

CCA Summer 2004 Newsletter - Children`s Craniofacial Association
CCA Summer 2004 Newsletter - Children`s Craniofacial Association

... (spontaneous gene mutation), and 70 percent of people with CCD have an affected parent. The condition is highly variable from one affected person to another. A brief review of chromosomes and genes may be helpful at this point. Genes are the basic units of heredity, and they are present in almost ev ...
Document
Document

Shelef, Katie: A Critical Analysis of Degenerate Primer Design Programs
Shelef, Katie: A Critical Analysis of Degenerate Primer Design Programs

... minimization of hybridization effects between a primer and itself [6]. The distance between the two ...
Perspectives in Diabetes Glucokinase Gene Structure
Perspectives in Diabetes Glucokinase Gene Structure

... isoform generated in the liver ( L l ) differs from those gen- generate the glucokinase activity measured in insulin-proerated in insulin-producing cells (B1 and 82) by sequences ducing cells. It would be surprising if activity of the B1 isoform at the NH,-terminal. This difference accounts for no m ...
Tracing the Thread of Plastid Diversity through the Tapestry of Life
Tracing the Thread of Plastid Diversity through the Tapestry of Life

... the plastid genome are encoded in the nuclear genome and must be targeted to the plastid. Three mechanisms underlie this reduction of the plastid genome; gene loss, substitution, and transfer. First, in the case of gene loss, genes that no longer confer a selective advantage in the endosymbiotic env ...
Evolutionary dynamics of nematode operons
Evolutionary dynamics of nematode operons

... inferred only when all of its constituent genes were still present in the genome, because we are interested in the separation of constituent genes of an operon, rather than gene loss. However, there is a small probability that although all of the constituent genes are present, some of them have beco ...
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