Genomic overview of serine proteases
... from telomere to centromere and again, the distances between genes range from 4 to 9 kb (except between granzyme M and azurocidin 1 which is about 150 kb) (Fig. 3A). In order to study the extent of each locus, we examined all identified genes on either side of each cluster, for sequence similarity wi ...
... from telomere to centromere and again, the distances between genes range from 4 to 9 kb (except between granzyme M and azurocidin 1 which is about 150 kb) (Fig. 3A). In order to study the extent of each locus, we examined all identified genes on either side of each cluster, for sequence similarity wi ...
Further genetic evidence suggesting a role for the
... strength of the linkage observed. Indeed, this phenomenon could hold true for other regions of the genome linked with BMD in which no single gene with a large influence on BMD has been identified, a plausible theory considering the large number of genes thought to have a minor influence on the BMD phen ...
... strength of the linkage observed. Indeed, this phenomenon could hold true for other regions of the genome linked with BMD in which no single gene with a large influence on BMD has been identified, a plausible theory considering the large number of genes thought to have a minor influence on the BMD phen ...
Association Between Endothelial Nitric Oxide Synthase
... the risk of premature CAD in Taiwan. Our results were not totally unexpected, as other studies 27-34 yielded similar findings, including lack of association between eNOS polymorphisms and premature CAD in three studies 32-34. The inconsistent results in different populations may suggest an interacti ...
... the risk of premature CAD in Taiwan. Our results were not totally unexpected, as other studies 27-34 yielded similar findings, including lack of association between eNOS polymorphisms and premature CAD in three studies 32-34. The inconsistent results in different populations may suggest an interacti ...
The polymorphism in MUC1 gene in Nelore cattle
... variations in the Nelore cattle in which the alleles with 12 and 18 repeats have not been previously described in Bos taurus Piedmontese and Italian Friesian cattle (Rasero et al. 2002). The higher frequency of the alleles with minor sizes presented in this study is in contrast to the report of Sacc ...
... variations in the Nelore cattle in which the alleles with 12 and 18 repeats have not been previously described in Bos taurus Piedmontese and Italian Friesian cattle (Rasero et al. 2002). The higher frequency of the alleles with minor sizes presented in this study is in contrast to the report of Sacc ...
POSITION-EFFECT VARIEGATION AT SEVERAL
... was studied. In order to take these factors into account, the data were arranged in three ways. I n the first two columns, only flies showing some pigment were averaged. I n the next two columns, only flies showing smooth areas but no pigment were averaged, and in the next two columns, data on these ...
... was studied. In order to take these factors into account, the data were arranged in three ways. I n the first two columns, only flies showing some pigment were averaged. I n the next two columns, only flies showing smooth areas but no pigment were averaged, and in the next two columns, data on these ...
(1977) New Genes for Resistance to the Brown Planthopper in Rice
... with TN1 were crossed with IRl154-243, a selection with the recessive gene, bph 2 for resistance (7). Cultivars, whose F~ hybrids with TN1 were r~sistant, were crossed with IR1539-823, a dwarf selection that is homozygous for the dominant gene, Bph 1 for resistance (5). To determine the allelic rela ...
... with TN1 were crossed with IRl154-243, a selection with the recessive gene, bph 2 for resistance (7). Cultivars, whose F~ hybrids with TN1 were r~sistant, were crossed with IR1539-823, a dwarf selection that is homozygous for the dominant gene, Bph 1 for resistance (5). To determine the allelic rela ...
Linking Cognitive Neuroscience and Molecular Genetics: New Perspectives from Williams... Ursula Bellugi and Marie St. George (Eds.)
... Korenberg et al., 1996; Robinson et al., 1996). However, the number of expressed genes in these duplicated regions and their contribution to the WMS phenotype is unknown. The current report will illustrate the structure of the flanking duplications and suggest a possible relationship to the WMS brea ...
... Korenberg et al., 1996; Robinson et al., 1996). However, the number of expressed genes in these duplicated regions and their contribution to the WMS phenotype is unknown. The current report will illustrate the structure of the flanking duplications and suggest a possible relationship to the WMS brea ...
AUTISM AS A PARADIGMATIC COMPLEX GENETIC DISORDER
... with autism (28, 29). More research to characterize the serotonin system, particularly in the periphery, could yield important information about the abnormalities found in ASD. One example of this approach is an association mapping study of whole blood serotonin independent of psychiatric disorder, ...
... with autism (28, 29). More research to characterize the serotonin system, particularly in the periphery, could yield important information about the abnormalities found in ASD. One example of this approach is an association mapping study of whole blood serotonin independent of psychiatric disorder, ...
The Genetics of Spinal Muscular Atrophy
... Figure 6. This figure illustrates the three types of SMN1 mutations: deletions, gene conversion of SMN1 to SMN2, and single nucleotide point mutations. (a) Xs indicate a deletion. A deletion removes part or all of the SMN1 gene. (b) In the case of gene conversion, the SMN1 gene has been converted to ...
... Figure 6. This figure illustrates the three types of SMN1 mutations: deletions, gene conversion of SMN1 to SMN2, and single nucleotide point mutations. (a) Xs indicate a deletion. A deletion removes part or all of the SMN1 gene. (b) In the case of gene conversion, the SMN1 gene has been converted to ...
SNPs and Haplotypes
... ("snip") is a single base mutation in DNA. • SNPs are ‘conserved’ across the genome, often in patterns called ‘haplotype blocks’ • SNPs are the most simple form and most common source of genetic polymorphism in the human genome (90% of all human DNA polymorphisms are associated with SNPs). ...
... ("snip") is a single base mutation in DNA. • SNPs are ‘conserved’ across the genome, often in patterns called ‘haplotype blocks’ • SNPs are the most simple form and most common source of genetic polymorphism in the human genome (90% of all human DNA polymorphisms are associated with SNPs). ...
Interactions Between Genes Controlling Pathogenicity in the Flax
... In flax (Linum usitatissimum L.) 29 genes that confer resistance to flax rust caused by Melampsora lini (Ehrenb.) L6v. have been identified. These occur in five series of closely linked or allelic genes, designated K, L, M, N, and P, which contain 1, 13, 7, 3, and 5 genes, respectively (6,11,19,20). ...
... In flax (Linum usitatissimum L.) 29 genes that confer resistance to flax rust caused by Melampsora lini (Ehrenb.) L6v. have been identified. These occur in five series of closely linked or allelic genes, designated K, L, M, N, and P, which contain 1, 13, 7, 3, and 5 genes, respectively (6,11,19,20). ...
Occurrence of phosphate acquisition genes in Prochlorococcus cells
... suggest that lateral gene transfer is a relatively rare event. Alternatively, if phosphate acquisition genes are commonly transferred laterally between Prochlorococcus cells, there should be no linkage between the phylotype (and thereby the core genome of Prochlorococcus) and the presence or absence ...
... suggest that lateral gene transfer is a relatively rare event. Alternatively, if phosphate acquisition genes are commonly transferred laterally between Prochlorococcus cells, there should be no linkage between the phylotype (and thereby the core genome of Prochlorococcus) and the presence or absence ...
early RNs, crossing over initiates, then synapsis begins Chiasmata
... breakpoints using a high density of markers. To identify the di fferent sequence elements in the region, they sequenced the entire 140 kb region from both parents. ...
... breakpoints using a high density of markers. To identify the di fferent sequence elements in the region, they sequenced the entire 140 kb region from both parents. ...
Adaptation of Sucrose Metabolism in the Escherichia coli Wild
... addition to Salmonella enterica serovar Typhimurium LT2 revealed that the csc genes are located in a hot spot region for chromosomal rearrangements in enteric bacteria. The comparison further indicated that the csc genes might have been transferred relatively recently to the E. coli wild-type EC3132 ...
... addition to Salmonella enterica serovar Typhimurium LT2 revealed that the csc genes are located in a hot spot region for chromosomal rearrangements in enteric bacteria. The comparison further indicated that the csc genes might have been transferred relatively recently to the E. coli wild-type EC3132 ...
Molecualr Biology and Evolution
... made, but the NifD phylogeny lacked resolution. Here nifgene phylogeny is addressed with a phylogenetic analysis of a third and longer nifgene, nzyK. As part of the study, the nifK gene of the key taxon Frankia was sequenced. Parsimony and some distance analyses of the nifK amino acid sequences prov ...
... made, but the NifD phylogeny lacked resolution. Here nifgene phylogeny is addressed with a phylogenetic analysis of a third and longer nifgene, nzyK. As part of the study, the nifK gene of the key taxon Frankia was sequenced. Parsimony and some distance analyses of the nifK amino acid sequences prov ...
Principal Components Analysis
... matrix. Eigenvectors can be thought of as “preferential directions” of a data set, or in other words, main patterns in the data. For PCA on genes, an eigenvector would be represented as an expression profile that is most representative of the data (see Fig.9). For PCA on conditions, an eigenvector c ...
... matrix. Eigenvectors can be thought of as “preferential directions” of a data set, or in other words, main patterns in the data. For PCA on genes, an eigenvector would be represented as an expression profile that is most representative of the data (see Fig.9). For PCA on conditions, an eigenvector c ...
Nonconventional Initiation Complex Assembly by STAT and NF
... A. Macrophages with IFN-I + hkL -> increase of histone acetylation at both the proximal and distal promoter locations B. Treatment with IFN-I -> increase of H4 acetylation at the distal IFN response region C. hkL treatment -> increase in H4 acetylation at the proximal NF-κB element ISGF3 and NF-κB ...
... A. Macrophages with IFN-I + hkL -> increase of histone acetylation at both the proximal and distal promoter locations B. Treatment with IFN-I -> increase of H4 acetylation at the distal IFN response region C. hkL treatment -> increase in H4 acetylation at the proximal NF-κB element ISGF3 and NF-κB ...
Gene Regulation and Systems Biology GA
... the kinetic parameter space, it is more likely to converge toward the globally optimal tracking solution. The proposed GA-based design algorithm is inspired by the mechanics of natural selection to a population of binary strings encoding the parameter space. At each generation, it explores differen ...
... the kinetic parameter space, it is more likely to converge toward the globally optimal tracking solution. The proposed GA-based design algorithm is inspired by the mechanics of natural selection to a population of binary strings encoding the parameter space. At each generation, it explores differen ...
Antibiotic resistance genes and identification of staphylococci
... genes was commonly found in individual Gram-positive bacteria (Schwarz et al., 1998; Huys et al., 2005; Rizzotti et al., 2005). The high incidence of tet(K) and tet(M) genes in the isolated staphylococci, 89.4% and 74.2%, respectively, can be explained by their usual genetic locations. In fact, the ...
... genes was commonly found in individual Gram-positive bacteria (Schwarz et al., 1998; Huys et al., 2005; Rizzotti et al., 2005). The high incidence of tet(K) and tet(M) genes in the isolated staphylococci, 89.4% and 74.2%, respectively, can be explained by their usual genetic locations. In fact, the ...
Castric et al. (MBE 2010) - GEPV
... these two effects remains to be determined, both theoretically and empirically. A second distinctive feature of the molecular evolution of SI genes is the role played by recombination and/or gene conversion. Indeed, whether recombination occurs at all in the genomic region of the S-locus is still a ...
... these two effects remains to be determined, both theoretically and empirically. A second distinctive feature of the molecular evolution of SI genes is the role played by recombination and/or gene conversion. Indeed, whether recombination occurs at all in the genomic region of the S-locus is still a ...
A series of promoters for constitutive expression of heterologous
... expression of heterologous genes have been developed (Bellemare et al., 2001; Erler et al., 2006; Fujita et al., 2006; Iacovoni et al., 1999). These types of inducible promoters are very useful for the maintenance of cloned genes that have harmful effects on cell growth, and timely expression to inv ...
... expression of heterologous genes have been developed (Bellemare et al., 2001; Erler et al., 2006; Fujita et al., 2006; Iacovoni et al., 1999). These types of inducible promoters are very useful for the maintenance of cloned genes that have harmful effects on cell growth, and timely expression to inv ...
Two enhancer regions in the mouse En-2 locus
... CNS, En-2 is expressed in cells surrounding the developing pituitary (Davis et al., 1988, 1991). In addition, immunohistochemical analysis using a polyclonal antiserum (aEnhb-1) that detects both En-1 and En-2 protein has shown that one or both genes are expressed in presumptive myoblasts within the ...
... CNS, En-2 is expressed in cells surrounding the developing pituitary (Davis et al., 1988, 1991). In addition, immunohistochemical analysis using a polyclonal antiserum (aEnhb-1) that detects both En-1 and En-2 protein has shown that one or both genes are expressed in presumptive myoblasts within the ...
Chapter 4: Individual gene function
... Loss-of-function mutations can be constructed With a genome sequence, sometimes we may see potential gene products where we may wish to know the importance of this gene product on an organism. For example, perhaps there is a new protein that has been associated with a particular disease, but the mec ...
... Loss-of-function mutations can be constructed With a genome sequence, sometimes we may see potential gene products where we may wish to know the importance of this gene product on an organism. For example, perhaps there is a new protein that has been associated with a particular disease, but the mec ...
Handout - 6 - CM - Outline Genomic Model for HL7 V2
... Acyl-CoA dehydrogenase family, member 9, deficiency of ...
... Acyl-CoA dehydrogenase family, member 9, deficiency of ...
Mapping avirulence genes in the rice blast fungus Magnaporthe grisea
... genes. We have identified three genetically independent avirulence genes in M. grisea (AvrMedNoï-1, AvrIrat7-1, AvrKu86-1). Analysis of the segregation of avirulence towards a collection of rice cultivars suggests the occurrence of the same resistance gene in unrelated cultivars. In order to clone a ...
... genes. We have identified three genetically independent avirulence genes in M. grisea (AvrMedNoï-1, AvrIrat7-1, AvrKu86-1). Analysis of the segregation of avirulence towards a collection of rice cultivars suggests the occurrence of the same resistance gene in unrelated cultivars. In order to clone a ...