Optimizing selection for quantitative traits with information on an
... can maximize genetic progress in the short term (i.e. in the current generation), they may not maximize response to selection in the longer term. In fact, Gibson (1994) found that traditional selection, based on phenotypic information alone, resulted in greater genetic improvement in the longer term ...
... can maximize genetic progress in the short term (i.e. in the current generation), they may not maximize response to selection in the longer term. In fact, Gibson (1994) found that traditional selection, based on phenotypic information alone, resulted in greater genetic improvement in the longer term ...
Leukaemia Section 3q rearrangements in myeloid malignancies Atlas of Genetics and Cytogenetics
... associated with ectopic EVI1 expression share the same prognostic features, however, has not been addressed. ...
... associated with ectopic EVI1 expression share the same prognostic features, however, has not been addressed. ...
Induction of the hair growth phase in postnatal mice by localized
... Induction of hair follicle growth and melanogenesis after intradermal administration of AdShh. AdShh, AdNull, or PBS was administered to the dorsal skin of postnatal day 19 C57BL/6 mice as in Figure 1c, and analyses were performed on postnatal day 26. (a) Histologic evaluation 7 days after vector ad ...
... Induction of hair follicle growth and melanogenesis after intradermal administration of AdShh. AdShh, AdNull, or PBS was administered to the dorsal skin of postnatal day 19 C57BL/6 mice as in Figure 1c, and analyses were performed on postnatal day 26. (a) Histologic evaluation 7 days after vector ad ...
Early Onset of Severe Familial Amyotrophic Lateral Sclerosis with a
... Motoneuron disease in mice with combined CNTF and SOD-1 gene defects. A, CNTF genotyping of mice. Ethidium bromide–stained 2% agarose gel reveals bands of 97 bp for the wild-type allele (CNTF⫹/⫹) and 1.197 bp for the mutated allele (CNTF⫺/⫺). Heterozygous mice (CNTF⫹/⫺) show both bands. “M” denotes ...
... Motoneuron disease in mice with combined CNTF and SOD-1 gene defects. A, CNTF genotyping of mice. Ethidium bromide–stained 2% agarose gel reveals bands of 97 bp for the wild-type allele (CNTF⫹/⫹) and 1.197 bp for the mutated allele (CNTF⫺/⫺). Heterozygous mice (CNTF⫹/⫺) show both bands. “M” denotes ...
The Interaction between Dietary Protein and Bone Health
... We did a search of PubMed looking at all articles generated by searching dietary protein, soy protein and milk protein respectively and either bone, bone density or fractures. All papers generally dealing with human subjects and the interaction between dietary protein and bone density, bone markers ...
... We did a search of PubMed looking at all articles generated by searching dietary protein, soy protein and milk protein respectively and either bone, bone density or fractures. All papers generally dealing with human subjects and the interaction between dietary protein and bone density, bone markers ...
Safety Assessment of Soy Proteins and Peptides as Used in
... 71 kDa) and β (ca 50 kDa). The 11S globulin is a hexamer, and is made up of five different subunits, each of which consists of an acidic subunit A (ca 35 kDa) and a basic subunit B (ca 20 kDa), linked by a disulfide bond. The 11S globulin was found to dissociate into 2S, 3S or 7S forms in solutions ...
... 71 kDa) and β (ca 50 kDa). The 11S globulin is a hexamer, and is made up of five different subunits, each of which consists of an acidic subunit A (ca 35 kDa) and a basic subunit B (ca 20 kDa), linked by a disulfide bond. The 11S globulin was found to dissociate into 2S, 3S or 7S forms in solutions ...
122602 Hydrophobic Surfactant Proteins in Lung Function
... ratory failure have been identified.17 Most infants with such a mutation present with progressive respiratory failure in the first 24 to 48 hours of life. Pulmonaryfunction studies and radiographic findings in these infants are consistent with surfactant deficiency. The disorder is usually inherited ...
... ratory failure have been identified.17 Most infants with such a mutation present with progressive respiratory failure in the first 24 to 48 hours of life. Pulmonaryfunction studies and radiographic findings in these infants are consistent with surfactant deficiency. The disorder is usually inherited ...
An improved Escherichia coli donor strain for diparental mating
... and a carbon source that cannot be utilized by E. coli, for example minimal medium with 0.3% citrate (Hoang et al., 1998). One drawback of a minimal medium might be slower growth of the recipient strains, and it is clearly not applicable for auxotrophic recipient strains. Another possibility is the ...
... and a carbon source that cannot be utilized by E. coli, for example minimal medium with 0.3% citrate (Hoang et al., 1998). One drawback of a minimal medium might be slower growth of the recipient strains, and it is clearly not applicable for auxotrophic recipient strains. Another possibility is the ...
Large-scale Analysis of Pseudogenes in the Human Genome
... component of phagocyte NADPH oxidase complex, complicates the detection of chronic granulomatous disease [42,43]. ...
... component of phagocyte NADPH oxidase complex, complicates the detection of chronic granulomatous disease [42,43]. ...
Candidate gene scan for Single Nucleotide Polymorphisms involved
... significant associations with 34 intergenic and extragenic SNPs. The majority of associations ...
... significant associations with 34 intergenic and extragenic SNPs. The majority of associations ...
Effect of the Polymorphisms of Keratin Associated Protein 8.2 Gene
... forty-two animals were used to detect polymorphisms in the complete coding sequence of the hircine KAP8.2 gene by means of PCRSSCP. The results identified six genotypes, AA, BB, DD, AB, AD and BD, coded for by three different alleles A, B and D. Two SNPs in the coding region were confirmed by sequen ...
... forty-two animals were used to detect polymorphisms in the complete coding sequence of the hircine KAP8.2 gene by means of PCRSSCP. The results identified six genotypes, AA, BB, DD, AB, AD and BD, coded for by three different alleles A, B and D. Two SNPs in the coding region were confirmed by sequen ...
Useful Information for Lay People
... number of other experts. Thus a neurologist may be required to help in making the initial diagnosis and for periodic re views; an orthopaedic surgeon can sometimes help with operative intervention of appliances for foot and spinal deformities; an expert in physical medicine in the matter of exercise ...
... number of other experts. Thus a neurologist may be required to help in making the initial diagnosis and for periodic re views; an orthopaedic surgeon can sometimes help with operative intervention of appliances for foot and spinal deformities; an expert in physical medicine in the matter of exercise ...
Pharmacogenetics of warfarin: current status and future
... risk of bleeding are influenced by environmental factors such as the intake of vitamin K, illness, age, gender, concurrent medication and body surface area, and by genetic variation.1–8 To be able to improve the benefit–harm profile associated with warfarin therapy, all these factors need to be take ...
... risk of bleeding are influenced by environmental factors such as the intake of vitamin K, illness, age, gender, concurrent medication and body surface area, and by genetic variation.1–8 To be able to improve the benefit–harm profile associated with warfarin therapy, all these factors need to be take ...
Gene Section WWC1 (WW and C2 domain containing 1)
... The gene of WWC1 locates on chromosome 5q34, with 23 exons crossing 180244bp (including untranslated regions) on the plus strand. In total 137 single nucleotide polymorphisms are present in ≥ 1% of samples according to UCSC database. ...
... The gene of WWC1 locates on chromosome 5q34, with 23 exons crossing 180244bp (including untranslated regions) on the plus strand. In total 137 single nucleotide polymorphisms are present in ≥ 1% of samples according to UCSC database. ...
Chapter 1: What is PKU?
... 15,000 babies born in the United States1. A person with PKU does not produce enough of an enzyme in their liver called phenylalanine hydroxylase (PAH). This enzyme is needed to process the amino acid, phenylalanine (Phe), which is found in food items that contain protein2. Usually, when people eat p ...
... 15,000 babies born in the United States1. A person with PKU does not produce enough of an enzyme in their liver called phenylalanine hydroxylase (PAH). This enzyme is needed to process the amino acid, phenylalanine (Phe), which is found in food items that contain protein2. Usually, when people eat p ...
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... Sex-Linked genes are genes on the Z chromosome. Roosters have two Z chromosomes and hens have only one Z chromosome, plus one W chromosome. As the hens only have one sex-linked allele for any given locus, both dominant and recessive sex-linked genes are expressed with just one gene (as hemizygous). ...
... Sex-Linked genes are genes on the Z chromosome. Roosters have two Z chromosomes and hens have only one Z chromosome, plus one W chromosome. As the hens only have one sex-linked allele for any given locus, both dominant and recessive sex-linked genes are expressed with just one gene (as hemizygous). ...
PhD Thesis Secondary metabolism and its regulation in
... compounds, insecticides, or herbicides. However, with the increasing bacterial resistance against routinely used antibiotics and the presence of still uncured diseases like cancer or AIDS, there is a very urgent need for new bioactive molecules. Important reservoirs of such bioactive compounds are t ...
... compounds, insecticides, or herbicides. However, with the increasing bacterial resistance against routinely used antibiotics and the presence of still uncured diseases like cancer or AIDS, there is a very urgent need for new bioactive molecules. Important reservoirs of such bioactive compounds are t ...
Single Nucleotide Polymorphism (SNP) of the Endothelial Nitric
... regionalized it to 7q35–q36. eNOS and nNOS are isoforms of constitutive NOS, and they are involved in cellular signaling pathways (Brenman et al, 1996). Both enzymes are calcium/calmodulin dependent, and they are rapidly activated by agonists that elevate intracellular free Ca2+ (Sessa et al, 1993). ...
... regionalized it to 7q35–q36. eNOS and nNOS are isoforms of constitutive NOS, and they are involved in cellular signaling pathways (Brenman et al, 1996). Both enzymes are calcium/calmodulin dependent, and they are rapidly activated by agonists that elevate intracellular free Ca2+ (Sessa et al, 1993). ...
Exam Questions from Exam 1 – Basic Genetic Tests
... Next you isolate a mutant strain of yeast that cannot grow on medium lacking leucine. This strain contains a single mutation you call leu1–. The leu1– mutation is near to drk1– on the same chromosome. When the leu1– mutant is mated to wild-type yeast, the resulting diploids cannot grow on medium lac ...
... Next you isolate a mutant strain of yeast that cannot grow on medium lacking leucine. This strain contains a single mutation you call leu1–. The leu1– mutation is near to drk1– on the same chromosome. When the leu1– mutant is mated to wild-type yeast, the resulting diploids cannot grow on medium lac ...
Tomé, S., Manley, K., Simard, J.P., Clark, G.W., Slean, M.M., Swami
... in human HD and DM1 stem cells [38]. MMR is a pathway dedicated to protecting against mutations arising from mispaired nucleotides and insertion/deletion loops [39]. There are two heterodimeric protein complexes that recognize unpaired DNAs: MutSa consists of MSH2-MSH6, and MutSb is formed by MSH2–M ...
... in human HD and DM1 stem cells [38]. MMR is a pathway dedicated to protecting against mutations arising from mispaired nucleotides and insertion/deletion loops [39]. There are two heterodimeric protein complexes that recognize unpaired DNAs: MutSa consists of MSH2-MSH6, and MutSb is formed by MSH2–M ...
A chitin-binding domain in a marine bacterial
... contrast, catalytic domains of cellulases do not appear to follow phylogeny, although cellulose-binding domains in cellulases from a single bacterium can be quite similar (Gilkes et al., 1991). T o gain a better understanding of bacterial chitinases and especially the chitin-binding domain, we exami ...
... contrast, catalytic domains of cellulases do not appear to follow phylogeny, although cellulose-binding domains in cellulases from a single bacterium can be quite similar (Gilkes et al., 1991). T o gain a better understanding of bacterial chitinases and especially the chitin-binding domain, we exami ...
