Neonatal Hyperbilirubinemia and Organic Anion Transporting
... NY), kernicterus still occurs; these cases highlight the need for continued study of the etiology of hyperbilirubinemia.19 Neither hyperbilirubinemia nor kernicterus are reportable diseases, and there are no reliable sources of information providing national annual estimates.19 The primary risk fact ...
... NY), kernicterus still occurs; these cases highlight the need for continued study of the etiology of hyperbilirubinemia.19 Neither hyperbilirubinemia nor kernicterus are reportable diseases, and there are no reliable sources of information providing national annual estimates.19 The primary risk fact ...
Chemically Mediated Site-Specific Proteolysis. Alteration of Protein
... To test the feasibility of this strategy at the level of a protein complex, the ecotin-trypsin complex was chosen as a model system. Ecotin, a homodimer protein present in E. coli, is a potent, competitive inhibitor of serine proteases (17). Ecotin is unique in its ability to inhibit a range of seri ...
... To test the feasibility of this strategy at the level of a protein complex, the ecotin-trypsin complex was chosen as a model system. Ecotin, a homodimer protein present in E. coli, is a potent, competitive inhibitor of serine proteases (17). Ecotin is unique in its ability to inhibit a range of seri ...
the art and design of genetic screens
... Geneticists use both forward and reverse selections. A forward selection allows the growth of mutants in which a particular gene function is lost. For example, the selection used by Luria and Delbruck3 for resistance to phage T1 is a forward selection that allows the growth of bacteria that have los ...
... Geneticists use both forward and reverse selections. A forward selection allows the growth of mutants in which a particular gene function is lost. For example, the selection used by Luria and Delbruck3 for resistance to phage T1 is a forward selection that allows the growth of bacteria that have los ...
Identification of a novel duplication in the APC gene using multiple
... Germline mutations in the adenomatous polyposis coli (APC ) gene cause familial adenomatous polyposis (FAP), an autosomal dominant disease characterized by hundreds to thousands of adenomatous polyps in the colon and rectum, with progression to colorectal cancer. The majority of APC mutations are nu ...
... Germline mutations in the adenomatous polyposis coli (APC ) gene cause familial adenomatous polyposis (FAP), an autosomal dominant disease characterized by hundreds to thousands of adenomatous polyps in the colon and rectum, with progression to colorectal cancer. The majority of APC mutations are nu ...
SEARCH_16S: A new algorithm for identifying 16S
... The start and end of the gene are found by searching a candidate segment for the boundary motifs C11F = GNTTGATCNTGNC and C1512R = AGTCNNAACAAGGTANCNNTA, allowing up to four mismatches and choosing the match with fewest differences. If matches to both motifs are found, and the sequence truncated to ...
... The start and end of the gene are found by searching a candidate segment for the boundary motifs C11F = GNTTGATCNTGNC and C1512R = AGTCNNAACAAGGTANCNNTA, allowing up to four mismatches and choosing the match with fewest differences. If matches to both motifs are found, and the sequence truncated to ...
Best Plant Protein
... Dietary protein is consumed from myriad food sources, and each contains a unique non-protein content that can have different health related effects aside from their respective contributions on muscle protein synthesis (MPS). 1,2,3 Little argument remains about whole animal, non-milk proteins (so-cal ...
... Dietary protein is consumed from myriad food sources, and each contains a unique non-protein content that can have different health related effects aside from their respective contributions on muscle protein synthesis (MPS). 1,2,3 Little argument remains about whole animal, non-milk proteins (so-cal ...
Review Molecular Biology in Arteriosclerosis Research
... sequencing of cell-free translation products. For most of the proteins listed in Table 3, however, amino acid sequence data is not available, and cDNA clones will be the most direct way to obtain this information when the protein can not easily be purified in amounts sufficient for classical analysi ...
... sequencing of cell-free translation products. For most of the proteins listed in Table 3, however, amino acid sequence data is not available, and cDNA clones will be the most direct way to obtain this information when the protein can not easily be purified in amounts sufficient for classical analysi ...
Genotype and Phenotype Powerpoint
... JOURNAL QUESTION Male alleles are both brown. Female alleles are brown and white. Show the possible outcomes for the offspring. ...
... JOURNAL QUESTION Male alleles are both brown. Female alleles are brown and white. Show the possible outcomes for the offspring. ...
Plant–nematode interactions
... plant-parasitic nematodes Broad investigations of the genomes and gene products of plant-parasitic nematodes are also underway. More than 200 000 nematode ESTs from 28 nematode species, excluding C. elegans but including 19 animal- and seven plant-parasitic nematode species, have been produced [42]. ...
... plant-parasitic nematodes Broad investigations of the genomes and gene products of plant-parasitic nematodes are also underway. More than 200 000 nematode ESTs from 28 nematode species, excluding C. elegans but including 19 animal- and seven plant-parasitic nematode species, have been produced [42]. ...
as Word 2000
... In Phase 1, if there is insufficient food for an amoeba, and it would otherwise starve, it may attempt to attack another amoeba in the same space. The attack costs 1 BP and is always successful unless the defending amoeba possesses Defense, Escape, or Armor. If the attack is successful unless the ot ...
... In Phase 1, if there is insufficient food for an amoeba, and it would otherwise starve, it may attempt to attack another amoeba in the same space. The attack costs 1 BP and is always successful unless the defending amoeba possesses Defense, Escape, or Armor. If the attack is successful unless the ot ...
MAMMALS THAT BREAK THE RULES:Genetics of Marsupials and
... identification of DNA markers in intersubspecific crosses will greatly facilitate linkage analysis (61). Even limited data were sufficient to establish that the marsupial genome follows its own rules of recombination. Linkage mapping in a dasyurid species showed that recombination rates are striking ...
... identification of DNA markers in intersubspecific crosses will greatly facilitate linkage analysis (61). Even limited data were sufficient to establish that the marsupial genome follows its own rules of recombination. Linkage mapping in a dasyurid species showed that recombination rates are striking ...
the Gene Ontology
... Bio-ontologies are used to capture biological information in a way that can be read by both humans and computers. necessary for high-throughput “omics” datasets allows data sharing across databases ...
... Bio-ontologies are used to capture biological information in a way that can be read by both humans and computers. necessary for high-throughput “omics” datasets allows data sharing across databases ...
Molecular Design of Expression Systems
... typically grown to high densities with minimal cloned gene expression followed by a production phase in which high expression results from induction or derepresSeveral different sion of cloned gene transcripti~n.'~?~~ promoter-operator systems, including lac, trp, and hPL, have been cloned and utili ...
... typically grown to high densities with minimal cloned gene expression followed by a production phase in which high expression results from induction or derepresSeveral different sion of cloned gene transcripti~n.'~?~~ promoter-operator systems, including lac, trp, and hPL, have been cloned and utili ...
EIN4 and ERS2 Are Members of the Putative Ethylene Receptor
... yeast osmolarity sensing pathway (Maeda et al., 1994). Alternately, the ethylene receptors could interact directly with CTR1 (Clark et al., 1998). EIN3 acts downstream of ETR1 and CTR1. It encodes a novel nuclear-localized protein and probably is involved in transcriptional regulation (Chao et al., ...
... yeast osmolarity sensing pathway (Maeda et al., 1994). Alternately, the ethylene receptors could interact directly with CTR1 (Clark et al., 1998). EIN3 acts downstream of ETR1 and CTR1. It encodes a novel nuclear-localized protein and probably is involved in transcriptional regulation (Chao et al., ...
A Bayesian Network Classification Methodology for Gene
... is labeled—associating with each training case the class to which it belongs—supports statistical methods for constructing a classifier. After training on a collection of labeled data, a classifier is constructed which, when presented with new query cases, predicts a class label from gene expression ...
... is labeled—associating with each training case the class to which it belongs—supports statistical methods for constructing a classifier. After training on a collection of labeled data, a classifier is constructed which, when presented with new query cases, predicts a class label from gene expression ...
Promoter Analysis of the Mouse Sterol Regulatory Element
... abolished the basal activity, demonstrating that this NF-Y site is essential for basal promoter activity of SREBP-1c. SREBP Activation of the Mouse SREBP-1c Gene Promoter— The SRE containing promoters analyzed to date in sterol-regulated genes contain NF-Y or Sp1 sites adjacent to SREs, and these co ...
... abolished the basal activity, demonstrating that this NF-Y site is essential for basal promoter activity of SREBP-1c. SREBP Activation of the Mouse SREBP-1c Gene Promoter— The SRE containing promoters analyzed to date in sterol-regulated genes contain NF-Y or Sp1 sites adjacent to SREs, and these co ...
Mapping the Genetic Architecture of Gene Expression in Human Liver
... Genetic variants that are associated with common human diseases do not lead directly to disease, but instead act on intermediate, molecular phenotypes that in turn induce changes in higher-order disease traits. Therefore, identifying the molecular phenotypes that vary in response to changes in DNA a ...
... Genetic variants that are associated with common human diseases do not lead directly to disease, but instead act on intermediate, molecular phenotypes that in turn induce changes in higher-order disease traits. Therefore, identifying the molecular phenotypes that vary in response to changes in DNA a ...
3-23_Genetics
... we use to represent alleles? Alleles are different versions of the same gene/trait. We use CAPITAL and lowercase letters to represent them! ...
... we use to represent alleles? Alleles are different versions of the same gene/trait. We use CAPITAL and lowercase letters to represent them! ...
Molecular pathogenesis of feline leukemia virus
... polymerase chain reaction (PCR)-based genome walking have been applied to detect integration sites for kinds of retroviruses such as MuLV, ALV and human immunodeficiency virus (HIV) (Bushman et al., 2005; Uren et al., 2005). One of them, inverse PCR, has been established early. A lot of different in ...
... polymerase chain reaction (PCR)-based genome walking have been applied to detect integration sites for kinds of retroviruses such as MuLV, ALV and human immunodeficiency virus (HIV) (Bushman et al., 2005; Uren et al., 2005). One of them, inverse PCR, has been established early. A lot of different in ...
ANSWER KEY
... NO. This phage contains an amber mutation in a gene required for phage DNA replication, the first step of the lytic life cycle. Since the bacterial strain does not contain an amber suppressor tRNA, no phage replication--and thus no cell lysis—will occur during the infection. b) Predict whether all, ...
... NO. This phage contains an amber mutation in a gene required for phage DNA replication, the first step of the lytic life cycle. Since the bacterial strain does not contain an amber suppressor tRNA, no phage replication--and thus no cell lysis—will occur during the infection. b) Predict whether all, ...
Pol Is a Candidate for the Mouse Pulmonary
... United States (1). Although cigarette smoke is implicated in ⬃90% of male and 75– 80% of female lung cancer deaths, only ⬃15% of heavy smokers will ultimately develop lung cancer, which suggests that there is variation in individual susceptibility to lung cancer (2, 3). Inbred strains of mice vary m ...
... United States (1). Although cigarette smoke is implicated in ⬃90% of male and 75– 80% of female lung cancer deaths, only ⬃15% of heavy smokers will ultimately develop lung cancer, which suggests that there is variation in individual susceptibility to lung cancer (2, 3). Inbred strains of mice vary m ...
Statistical analysis of DNA microarray data
... Which genes to use for normalization Housekeeping genes Genes involved in essential activities of cell maintenance and survival, but not in cell function and proliferation These genes will be similarly expressed in all samples. Difficult to identify – need to be confirmed Affymetrix GeneC ...
... Which genes to use for normalization Housekeeping genes Genes involved in essential activities of cell maintenance and survival, but not in cell function and proliferation These genes will be similarly expressed in all samples. Difficult to identify – need to be confirmed Affymetrix GeneC ...
Introduction to GO Annotation
... encode a novel receptor-like kinase. We have shown that like other plant RLKs, the kinase domain of PERK1 has serine/threonine kinase activity, In addition, the location of a PERK1-GTP fusion protein to the plasma membrane supports the prediction that PERK1 is an integral membrane protein…these kina ...
... encode a novel receptor-like kinase. We have shown that like other plant RLKs, the kinase domain of PERK1 has serine/threonine kinase activity, In addition, the location of a PERK1-GTP fusion protein to the plasma membrane supports the prediction that PERK1 is an integral membrane protein…these kina ...