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It’s not ‘just’ about BIGDATA from BIGDATA
It’s not ‘just’ about BIGDATA from BIGDATA

PDF - NDSU Agriculture
PDF - NDSU Agriculture

... identified, isolated and cloned. In the laboratory, the mRNA molecule from a gene being expressed can be isolated and used as a template to synthesize a complementary DNA (cDNA) strand. This isolated cDNA strand then can be cloned ...
The Disease(text in English)
The Disease(text in English)

... The cause In general, mutations in CDKL5 are considered the cause of the disease if the are present in the child but not in the healthy parents. Therefore, these mutations arise “de novo” at the moment of the conception. The diagnosis The initial diagnosis is a clinical one or, with other words, bas ...
Could there be a Protective Gene?
Could there be a Protective Gene?

... Hereditary dementia in Australian families: could there be a protective gene? William Brooks, Olivier Piguet, Hayley Bennett, G Anthony Broe Prince of Wales Medical Research Institute ...
PowerPoint Presentation - Ch.14 Mendel and the Gene Idea
PowerPoint Presentation - Ch.14 Mendel and the Gene Idea

... Codominance • Codominance - A and B are both dominant to O but not to each other, giving the AB blood type ...
Chapter 10: Retroelements in the Mouse
Chapter 10: Retroelements in the Mouse

... True or False? The germline content of ecotropic, xenotropic and polytropic MuLV has been shown to undergo gain or loss due to reinsertions or deletions in germ cells; loss of germline proviruses seems to occur more frequently than gain. Which of these statements regarding proviral reinsertion is fa ...
Carlson - Karola Stotz
Carlson - Karola Stotz

... to components of the cytoplasm made it harder to describe a gene as simply the maker of a product. Genes could be temporarily altered by methylation and their association with histones. The production of sperm or eggs differed in which genes were temporarily switched off. There were more proteins th ...
The Plant Resistance Gene Database (PRGdb): a Wiki
The Plant Resistance Gene Database (PRGdb): a Wiki

... conferring resistance to 122 different pathogens. Available classification is made up from a custom pipeline called Disease Resistance Analysis and Gene Orthology (DRAGO), based on reference R-gene curated sequence data and developed to search for plant resistance genes in public datasets such as Un ...
Kein Folientitel
Kein Folientitel

...  If possible, discard 3’-UTR beyond first polyA signal  Look for alternative splice events  Use remaining region of interest for similarity searches  Mask regions that could cross-hybridize  Use the remaining region for probe amplification or EST selection  When working with ESTs, use sequence ...
Genetically Modified Food
Genetically Modified Food

... Mechanism1 : Isolating/synthesizing the target gene  The ‘shotgun’ approach, using type II restriction enzyme(restriction endonuclease ) - the enzyme cuts at recognition sites, to obtain a desired gene - sticky ends or blunt ends produced (there are figures later)  Making a copy of the gene from ...
IntroducTon to Biological sequences
IntroducTon to Biological sequences

... DNA's Double Helix. DNA molecules are found inside the cell's nucleus, tightly packed into chromosomes. Scientists use the term "double helix" to describe DNA's winding, two-stranded chemical structure. Alternating sugar and phosphate groups form the helix's two parallel strands, which run in opposi ...
Defective de novo methylation of viral and cellular DNA sequences
Defective de novo methylation of viral and cellular DNA sequences

... satellite 2 repeats (on chromosomes 1 and 16) • The overall reduction in cellular 5-methylcytosine levels was about 7% • A number of genes on the inactive X chromosome have been found to be hypomethylated in ICF cells • Genes whose expression was aberrantly up- or downregulated in ICF do not have de ...
Bio1A Unit 1-2 Biological Molecules Notes File
Bio1A Unit 1-2 Biological Molecules Notes File

... (think of a street cars going opposite directions) Function – “backup” copy in case of damage ...
Costello Syndrome - South West Thames Regional Genetics Service
Costello Syndrome - South West Thames Regional Genetics Service

Protein synthesis
Protein synthesis

... taking the code of DNA to mRNA and eventually from mRNA to protein. • In other words, the flow of information in a cell goes from: DNA mRNA Protein ...
Douillard found that Flik
Douillard found that Flik

... Cy5 hp0906KO (C1) with Cy3 CCUG17874 (A3) → Hyb:32525 Cy3 CCUG17874 (A3)-23856 with Cy5 CCUG17874 (C1) → Hyb:32519 Cy5 hp0906KO (B1) with Cy3 CCUG17874 (A2) → Hyb:32524 Cy3 CCUG17874 (A1) with Cy5 hp0906KO (A1) → Hyb:32523 Cy5 CCUG17874 (B1) with Cy3 NCTC26695 (B1) → Hyb:32528 Cy3 CCUG17874 (A5) wit ...
Study_Guide_for_Exam_2
Study_Guide_for_Exam_2

... Different versions of the same gene are called… What is the name of the location of a gene ...
highly specific nucleases for gene targeting and
highly specific nucleases for gene targeting and

... The new properties eliminate known disadvantages of conven-tionally used chimeric nucleases and allow to specifically modify genomes e.g. for biotechnological or gene therapeutic applications. The high specificity and preference of the new chimeric nucleases is based on a fusion of TALE proteins as ...
Genetics Outcomes
Genetics Outcomes

... 39. Describe the application of DNA profiling to determine paternity and also in forensic investigations. 40. Analyze DNA profiles to draw conclusions about paternity or forensic investigations. To do this, complete the Murder Mystery by using DNA profiling. (Will be handed out) 41. Outline three ou ...
STATE UNIVERSITY OF NEW YORK COLLEGE OF TECHNOLOGY CANTON, NEW  YORK
STATE UNIVERSITY OF NEW YORK COLLEGE OF TECHNOLOGY CANTON, NEW YORK

... molecular structure of DNA, DNA replication, transcription, translation, mRNA splicing, and the control of gene expression. Describe in detail the processes of mitosis and meiosis and how genes “move” between generations. 2. Describe the categories of mutations, 2. Critical thinking how mutations ar ...
Unit 11.1 Gene Transfer
Unit 11.1 Gene Transfer

... (Briefly describe the topics, methods, technology integration, etc.) ...
DNA
DNA

... called histones forming beads • These beads pack together, forming nucleosomes. • These coil to make chromatin • When the chromatin (stringy DNA) coils it make a chromosome ...
A Novel Interacting Protein With The DNA Mismatch Repair Gene
A Novel Interacting Protein With The DNA Mismatch Repair Gene

... dominant negative phenotype and microsatellite instability (MSI). Mutated PMS2 does not inhibit initial steps of MMR but interacts with and inhibits a downstream component of the MMR pathway. We hypothesize that the clone construct interacts with and is inhibited by DN-mutated PMS2 resulting in incr ...
Acute Promyelocytic Leukemia Molecular Testing
Acute Promyelocytic Leukemia Molecular Testing

... • RARA (retinoic acid receptor alpha) gene on chromosome 17q12.1 • Two fusion gene products result from this translocation, each of which encodes a functional chimeric protein ...
Chapter 14 Human Genetics
Chapter 14 Human Genetics

... • Genome = the full set of genetic information that an organism carries in its DNA • Karyotype = the complete diploid set of chromosomes grouped together ▫ Arranged in order of decreasing size ...
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RNA-Seq



RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.
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