More... - Stamm`s Lab
... anticipated. Since the transcriptome consists of at least 250,000 molecules, pre-mRNA processing events in humans contribute more significantly to human gene expression and regulation than previously thought. Recent array data show that more than 90% of all human genes are alternatively spliced. Cha ...
... anticipated. Since the transcriptome consists of at least 250,000 molecules, pre-mRNA processing events in humans contribute more significantly to human gene expression and regulation than previously thought. Recent array data show that more than 90% of all human genes are alternatively spliced. Cha ...
Carbonic Anhydrase I as a Novel Plasma Biomarker for Prostate
... diagnostic gray zone for finding prostate cancer, in which a biopsy would reveal no evidence of cancer in 75%. In order to discover a new biomarker with higher specificity for prostate cancer, we searched plasma proteins by our original proteomic technique. Materials and Methods: Plasma proteins fro ...
... diagnostic gray zone for finding prostate cancer, in which a biopsy would reveal no evidence of cancer in 75%. In order to discover a new biomarker with higher specificity for prostate cancer, we searched plasma proteins by our original proteomic technique. Materials and Methods: Plasma proteins fro ...
Mendelian Genetics
... • Linkage occurs when two genes are close to each other on the same chromosome. . • Genes far apart on the same chromosome assort independently: they are not linked. • Linkage is based on the frequency of crossing over between the two genes. Crossing over occurs in prophase of meiosis 1, where homol ...
... • Linkage occurs when two genes are close to each other on the same chromosome. . • Genes far apart on the same chromosome assort independently: they are not linked. • Linkage is based on the frequency of crossing over between the two genes. Crossing over occurs in prophase of meiosis 1, where homol ...
Mansi`s Powerpoint
... Previously, some developmental processes were thought to be conserved in the bilaterian ancestor ...
... Previously, some developmental processes were thought to be conserved in the bilaterian ancestor ...
Reproduction and Development
... • Each diploid organism has two units for each trait (one from mom and one from dad) • In parents different units assort independently into gametes (law of segregtion) – if dad is heterozygous you have 50% probability of getting one or the other allele ...
... • Each diploid organism has two units for each trait (one from mom and one from dad) • In parents different units assort independently into gametes (law of segregtion) – if dad is heterozygous you have 50% probability of getting one or the other allele ...
included data sources
... Life Sciences Sources – These are sources that life scientists directly consult some of which are widely known such as Pubmed, Uniprot, Chembl and many other biological sources. Semantic and Ontological Sources – These are sources like ontologies, structured vocabularies and thesauri that are oft ...
... Life Sciences Sources – These are sources that life scientists directly consult some of which are widely known such as Pubmed, Uniprot, Chembl and many other biological sources. Semantic and Ontological Sources – These are sources like ontologies, structured vocabularies and thesauri that are oft ...
anti-codon
... Protein Synthesis Building protein from DNA in cells Takes code on basepai Converts it to rs ...
... Protein Synthesis Building protein from DNA in cells Takes code on basepai Converts it to rs ...
Lect2 Genetics
... DNA polymerase can only extend 5’ to 3’. Leading strand is generated normally, lagging strand goes opposite way so is done in ‘Okazaki’ ...
... DNA polymerase can only extend 5’ to 3’. Leading strand is generated normally, lagging strand goes opposite way so is done in ‘Okazaki’ ...
ANIMAL GENETICS
... Every gene from the male is paired with the same type of gene from the female. – Example: The gene that controls the color of the animal’s coat is made up of a pair of “coat color” genes-1 from father and 1 ...
... Every gene from the male is paired with the same type of gene from the female. – Example: The gene that controls the color of the animal’s coat is made up of a pair of “coat color” genes-1 from father and 1 ...
Inheritance-Act-1-3
... 1. I will be able to define the terms fertilisation, species, variation and chromosome and gene. 2. I will be able to relate my understanding of the process of fertilisation to the passing on of ...
... 1. I will be able to define the terms fertilisation, species, variation and chromosome and gene. 2. I will be able to relate my understanding of the process of fertilisation to the passing on of ...
nuclear structure (2): the nucleolus
... polymerase molecules. (3) The “branches” are the nascent 45S rRNA molecules. (4) At various locations along each “branch” (each nascent 45S rRNA molecule) are black dots. These are places where proteins have bound. (5) The nascent RNA molecules do not appear to be as long as the DNA template on whic ...
... polymerase molecules. (3) The “branches” are the nascent 45S rRNA molecules. (4) At various locations along each “branch” (each nascent 45S rRNA molecule) are black dots. These are places where proteins have bound. (5) The nascent RNA molecules do not appear to be as long as the DNA template on whic ...
The effect of isozymes on metabolic activity analysis
... Supplementary Table 1: Spearman rank correlation between flux level and mRNA/protein abundance, when isozymes are included. Values are based on flux levels from 1000 randomly sampled optimal flux distributions. ...
... Supplementary Table 1: Spearman rank correlation between flux level and mRNA/protein abundance, when isozymes are included. Values are based on flux levels from 1000 randomly sampled optimal flux distributions. ...
Divining Biological Pathway Knowledge from High
... • Show which genes belong to which gene sets • All genes shown are members of the MAPK signaling pathway ...
... • Show which genes belong to which gene sets • All genes shown are members of the MAPK signaling pathway ...
Ch 10: Genetic Change and Variation
... Blood groups are traced in families to act as gene markers. Correlation between certain blood groups alleles and the occurrence of a genetic disease can determine whether or not the gene for the disease is on the same chromosome as that for blood groups. If one genetic marker is not linked to the di ...
... Blood groups are traced in families to act as gene markers. Correlation between certain blood groups alleles and the occurrence of a genetic disease can determine whether or not the gene for the disease is on the same chromosome as that for blood groups. If one genetic marker is not linked to the di ...
TimeClust: a clustering tool for gene expression
... can be used in different conditions or for different purposes. HC can be used for a first exploratory analysis, also on a very large number of genes (even before gene selection). It is considered a sort of reference in gene expression data analysis and provides an output (the dendrogram) that is ext ...
... can be used in different conditions or for different purposes. HC can be used for a first exploratory analysis, also on a very large number of genes (even before gene selection). It is considered a sort of reference in gene expression data analysis and provides an output (the dendrogram) that is ext ...
Genes and RNA
... i.e., they are the same in most introns in most species. There is a GU at the 5’ splice site of the intron and an AG at the 3’ splice site in virtually all cases examined ("the GU-AG rule") Consensus sequences of 5’ and 3’ splice junctions in eukaryotic mRNAs. Almost all introns begin with GU and en ...
... i.e., they are the same in most introns in most species. There is a GU at the 5’ splice site of the intron and an AG at the 3’ splice site in virtually all cases examined ("the GU-AG rule") Consensus sequences of 5’ and 3’ splice junctions in eukaryotic mRNAs. Almost all introns begin with GU and en ...
Large-Scale High-Resolution Orthology Using Gene Trees
... • Why do we study gene-ancestry/gene-trees (phylogenies)? • Several approaches to find orthologous genes • High-resolution orthology • Steps involved • Things to think about (homework) ...
... • Why do we study gene-ancestry/gene-trees (phylogenies)? • Several approaches to find orthologous genes • High-resolution orthology • Steps involved • Things to think about (homework) ...
DNA, RNA, Protein synthesis, and Mutations
... Mutations that involve changes in one or a few nucleotides • occur at a single point in the DNA sequence • generally occur during replication. • If a gene in one cell is altered ...
... Mutations that involve changes in one or a few nucleotides • occur at a single point in the DNA sequence • generally occur during replication. • If a gene in one cell is altered ...
Identification and Chromosome Assignment of a Human Gene
... The 110-kDasubunit contains a C-terminal PI kinase domain, as well as a small domain of its N terminus that is sufficient for binding to the p85 subunit. The p85 subunit serves as an adapter and binds activated growth factor receptors and other tyrosine phosphorylated molecules through its two Src h ...
... The 110-kDasubunit contains a C-terminal PI kinase domain, as well as a small domain of its N terminus that is sufficient for binding to the p85 subunit. The p85 subunit serves as an adapter and binds activated growth factor receptors and other tyrosine phosphorylated molecules through its two Src h ...
Integrated genomic DNA/RNA profiling of
... 200 ng DNA undergoes whole-genome shotgun library construction. cDNA libraries are hybrid capture selected for 265 genes known to be rearranged in RNA and DNA libraries are hybrid capture selected for 405 genes known to be altered in DNA. Hybrid-capture selected libraries are sequenced to high depth ...
... 200 ng DNA undergoes whole-genome shotgun library construction. cDNA libraries are hybrid capture selected for 265 genes known to be rearranged in RNA and DNA libraries are hybrid capture selected for 405 genes known to be altered in DNA. Hybrid-capture selected libraries are sequenced to high depth ...
PSYC 2314 Chapter 3
... • X-linked Genes: genes that are on the X chromosome. – If an X-linked gene is recessive—as are the genes for most forms of color-blindness, many allergies, several diseases, and some learning disabilities—the fact that it is on the X chromosome is critical. ...
... • X-linked Genes: genes that are on the X chromosome. – If an X-linked gene is recessive—as are the genes for most forms of color-blindness, many allergies, several diseases, and some learning disabilities—the fact that it is on the X chromosome is critical. ...
Week 5
... Barr body: the form taken by one of the X chromosomes in each cell of females (XX). The chromosome appears as a clump in the nucleus. In this form it is inactive, thus providing dose compensation. CpG groups: portions of the DNA rich in the sequence Cytosine-Guanosine (as read from the 5’ end of the ...
... Barr body: the form taken by one of the X chromosomes in each cell of females (XX). The chromosome appears as a clump in the nucleus. In this form it is inactive, thus providing dose compensation. CpG groups: portions of the DNA rich in the sequence Cytosine-Guanosine (as read from the 5’ end of the ...
Genetics Vocabulary
... Definition: The genetic makeup of an organism. Often used to refer to a specific genetic allele which is responsible for specific observable trait (phenotype). A set of alleles which is responsible for a particular phenotype. Phenotype Definition: An observable, measurable characteristic of an organ ...
... Definition: The genetic makeup of an organism. Often used to refer to a specific genetic allele which is responsible for specific observable trait (phenotype). A set of alleles which is responsible for a particular phenotype. Phenotype Definition: An observable, measurable characteristic of an organ ...
10 gene expression: transcription
... consensus sequence is to follow these steps: 1. Consider each position of the sequences separately. 2. Count the number of different bases found at that position. 3. The base with the highest number is the one that will be included in the consensus sequence. For example, in position 1, there are 5 G ...
... consensus sequence is to follow these steps: 1. Consider each position of the sequences separately. 2. Count the number of different bases found at that position. 3. The base with the highest number is the one that will be included in the consensus sequence. For example, in position 1, there are 5 G ...
Saturday Study Session 2 Theme of the day: Information Transfer
... Discussion of the restriction enzyme creating matching sticky ends on each DNA strand. (1pt.) Discussion of the DNA pieces being combined using ligase to solidify the connects. (1 pt.) Discussion of the recombined plasmid being inserted back into the bacteria. (1pt.) ...
... Discussion of the restriction enzyme creating matching sticky ends on each DNA strand. (1pt.) Discussion of the DNA pieces being combined using ligase to solidify the connects. (1 pt.) Discussion of the recombined plasmid being inserted back into the bacteria. (1pt.) ...
RNA-Seq
RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.